Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group.

abstract：:Prior randomised studies of immunoglobulin replacement therapy have studied mixed populations with or without a history of infections. Immunoglobulin therapy is expensive and in limited supply suggesting that optimising patient selection is of value. In this retrospective study, infection history identified high-risk ...

journal_title：Internal medicine journal

authors： Paxton L,Hawkins C,Crispin P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemoradiation therapy (CRT) is standard of care treatment for locally advanced rectal cancer (LARC). A pathologic complete response (pCR) following CRT is an early indicator of treatment benefit and associated with excellent survival outcomes. As capecitabine replaces infusional 5-fluorouracil (...

journal_title：Internal medicine journal

authors： Loft M,Wong HL,Kosmider S,Lee M,Tie J,Wong R,Jones IT,Croxford M,Steel M,Faragher I,Guerrieri M,Christie M,Gibbs P

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND:The ACT Genetic Service at The Canberra Hospital evaluates the genetic risk of individuals for inherited diseases, and provides counselling and genetic testing where appropriate. AIM:To evaluate the current referral practice for patients with a personal and/or family history of breast and/or ovarian cancer,...

journal_title：Internal medicine journal

authors： Aitken L,Warwick L,Davis A

更新日期：2017-03-01 00:00:00

abstract：AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...

journal_title：Internal medicine journal

authors： Thorne K,Jayathissa S,Dee S,Briggs N,Taylor J,Reid S,De Silva K,Dean J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Poor sleep is common after stroke, and data regarding its effect on rehabilitation outcomes are limited. Controversial evidence was found concerning the effect of sedatives on improving sleep quality in poor sleepers after stroke. AIM:To assess the prevalence of poor sleep in post-stroke patients and its ef...

journal_title：Internal medicine journal

authors： Iddagoda MT,Inderjeeth CA,Chan K,Raymond WD

更新日期：2020-02-01 00:00:00

abstract：:The negative health effects of the 2003 invasion of Iraq should act as a watershed in the medical profession's approach to violent conflict. ...

journal_title：Internal medicine journal

authors： Huggan PJ

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Many studies support the role of bilirubin as a cytoprotector in chronic inflammatory diseases, such as stroke and atherosclerosis. AIM:To investigate the relationship between serum total bilirubin levels and functional dependence in older adults. METHODS:Data from the National Health and Nutrition Examina...

journal_title：Internal medicine journal

authors： Kao TW,Chou CH,Wang CC,Chou CC,Hu J,Chen WL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The thiopurines azathioprine and 6-mercaptopurine are recommended for maintenance of remission in inflammatory bowel disease (IBD). Measurement of concentrations of the metabolites 6-thioguanine nucleotide and 6-methylmercaptopurine helps delineate interindividual variation in metabolism that may underlie va...

journal_title：Internal medicine journal

authors： Kennedy NA,Asser TL,Mountifield RE,Doogue MP,Andrews JM,Bampton PA

更新日期：2013-03-01 00:00:00

abstract：:We describe three patients with severe refractory cutaneous polyarteritis nodosa, resulting in painful ulcers involving the lower limbs and causing toe necrosis. Due to the severity of the cutaneous manifestations, the three patients received intravenous immunoglobulins at a dose of 1 g/kg/day for 2 days monthly. Afte...

journal_title：Internal medicine journal

authors： Marie I,Miranda S,Girszyn N,Soubrane JC,Vandhuick T,Levesque H

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:In 2004, the Pharmaceutical Benefits Scheme (PBS) listed infliximab as a subsidised treatment for ankylosing spondylitis (AS). Eligibility to receive this treatment for AS involved fulfilling several criteria. AIM:To examine the medical literature concerning response to tumor necrosis factor (TNF)-alpha inh...

journal_title：Internal medicine journal

authors： Smith MD,Ahern MJ

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:The comparative effectiveness of biologic treatment regimens in a real world Australian population is unknown. AIM:To assess the effectiveness of biological disease-modifying anti-rheumatic drugs (bDMARD) as monotherapy or in combination with methotrexate and/or other conventional DMARD (cDMARD) for the tre...

journal_title：Internal medicine journal

authors： Nicholls D,Barrett R,Button P,Truman M,Bird P,Roberts L,Tymms K,Littlejohn G,Griffiths H

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The reported risk of depression in patients with hypomagnesaemia is controversial. AIM:The objective of this meta-analysis was to assess the association between depression and hypomagnesaemia. METHODS:A literature search was performed using MEDLINE, EMBASE, Cochrane Database and clinicaltrials.gov from inc...

journal_title：Internal medicine journal

authors： Cheungpasitporn W,Thongprayoon C,Mao MA,Srivali N,Ungprasert P,Varothai N,Sanguankeo A,Kittanamongkolchai W,Erickson SB

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:In Australia, antimicrobial stewardship programmes are a compulsory component of hospital accreditation. Good documentation around anti-microbial prescribing aids communication and can improve prescribing practice in environments with multiple decision makers. AIM:This study aims to develop and implement an...

journal_title：Internal medicine journal

authors： Chaves NJ,Ingram RJ,MacIsaac CM,Buising KL

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome occurs in one to six per 1000 pregnancies; maternal death has been reported in 1-24% of cases. Vague presentation is common; hypertension and proteinuria which characterise pre eclampsia are often absent when HELLP syndrome presents. Physi...

journal_title：Internal medicine journal

authors： Jayawardena L,Mcnamara E

更新日期：2020-03-01 00:00:00

abstract：:Many publications have highlighted a lack of practical competencies in recently qualified interns. Consultation between the University of Queensland and the Medical Education Unit at Redcliffe Hospital identified key areas where intervention could lead to greater work readiness, and the development of a complementary ...

journal_title：Internal medicine journal

authors： Costello J,Livett M,Stride PJ,West M,Premaratne M,Thacker D

更新日期：2010-10-01 00:00:00

abstract：:The aim of this study was to collate and evaluate studies investigating either the factors influencing work-related psychological distress in postgraduate year one (PGY1) doctors or the strategies designed to reduce it. This is a systematic review conducted in May 2014. The data sources were key databases (MEDLINE, Ps...

journal_title：Internal medicine journal

authors： Facey AD,Tallentire V,Selzer RM,Rotstein L

更新日期：2015-10-01 00:00:00

abstract：:Young onset dementia (YOD), where symptoms of dementia have an onset before the age of 65, has become more prominent due to the population increase from the Baby Boomer generation. This clinical perspective examines key issues in the assessment, diagnosis and management of YOD. Challenges in the assessment and diagnos...

journal_title：Internal medicine journal

authors： Draper B,Withall A

更新日期：2016-07-01 00:00:00

abstract：:It has been stated that academic medicine is in a worldwide crisis. Is this decline in hospital academic practice a predictable consequence of modern clinical practice with its emphasis on community and outpatient-based services as well as a corporate health-care ethos or does it relate to innate problems in the train...

journal_title：Internal medicine journal

authors： Wilson A

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Guidelines recommend screening for strongyloidiasis prior to immunosuppression in those at epidemiological risk, as hyperinfection following immunosuppression is often fatal. The uptake of this recommendation is unknown, and we aimed to explore this in our setting. AIMS:Determine the proportion of adult pat...

journal_title：Internal medicine journal

authors： Muhi S,Ko DK,McGuinness SL,Biggs BA,Mahanty S,Delany C

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Polyserositis (PS) is the inflammation, with effusion, of different serous membranes. It has been associated with different aetiologies, but the aetiology of PS remains unknown in a high percentage of patients. AIMS:The general objective of this retrospective study was to analyse the aetiology of PS cases s...

journal_title：Internal medicine journal

authors： Losada I,González-Moreno J,Roda N,Ventayol L,Borjas Y,Domínguez FJ,Fernández-Baca V,García-Gasalla M,Payeras A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Unrelated umbilical cord blood has emerged as an alternative stem cell source for allogeneic transplantation for patients with haematological malignancies, but in adults is limited by the low number of stem cells present in banked cord blood units. We report our experience with double cord blood transplants ...

journal_title：Internal medicine journal

authors： Bradstock K,Hertzberg M,Kerridge I,Svennilson J,George B,McGurgan M,Huang G,Antonenas V,Gottlieb D

更新日期：2009-11-01 00:00:00

abstract：:Cardiac involvement is not regarded as a feature of Henoch-Schönlein purpura (HSP). We report a patient with HSP who developed significant cardiac symptoms, which resolved with immunosuppression. We review previous cases of HSP with cardiac features, none of which showed a response to treatment, and discuss evidence t...

journal_title：Internal medicine journal

authors： Polizzotto MN,Gibbs SD,Beswick W,Seymour JF

更新日期：2006-05-01 00:00:00

abstract：:Changes in medical research ethics in the past two decades have made the communication of risk to potential participants a legal imperative. Using ethnographic data from two different cultures, we examine the hazards associated with medical research in relation to the respective societal contexts that imbue them with ...

journal_title：Internal medicine journal

authors： Parker DB,Barrett RJ

更新日期：2003-09-01 00:00:00

abstract：:There is accumulating evidence that point-of-care delivery of clinical information such as evidence-based medicine, practice guidelines and drug information can streamline clinical practice and reduce preventable errors. In Australia, hospital-based physicians have -generally been slow to fully use these resources to ...

journal_title：Internal medicine journal

authors： Wilcox RA,Whitham EM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The current results on the diagnostic accuracy of multidetector computed tomography (MDCT) in the detection of left atrial/left atrial appendage (LA/LAA) thrombus are conflicting. AIM:The aim of the present study was to determine the diagnostic accuracy of MDCT in LA/LAA thrombus with meta-ana...

journal_title：Internal medicine journal

authors： Ning Z,Min ZG,Jiang HX,Hu BL

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The reported prevalence of cognitive impairment in patients with stable chronic obstructive pulmonary disease (COPD) ranges 36-77%. Few studies report the prevalence of cognitive impairment in acutely unwell COPD patients. AIMS:To determine the prevalence and time course of cognitive impairment in patients ...

journal_title：Internal medicine journal

authors： Poot B,Travers J,Weatherall M,McGinty M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) is a subgroup of oncogene addicted lung cancer that predicts response to tyrosine kinase inhibitors (TKI). However, there is variability in response and survival outcomes in patients with EGFR mutation treated with TKI. AIM:T...

journal_title：Internal medicine journal

authors： Ding PN,Roberts TL,Chua W,Becker TM,Descallar J,Yip PY,Bray V

更新日期：2017-12-01 00:00:00

abstract：:The Australian Clinical Guidelines for Stroke Management 2010 represents an update of the Clinical Guidelines for Stroke Rehabilitation and Recovery (2005) and the Clinical Guidelines for Acute Stroke Management (2007). For the first time, they cover the whole spectrum of stroke, from public awareness and prehospital ...

journal_title：Internal medicine journal

authors： Wright L,Hill KM,Bernhardt J,Lindley R,Ada L,Bajorek BV,Barber PA,Beer C,Golledge J,Gustafsson L,Hersh D,Kenardy J,Perry L,Middleton S,Brauer SG,Nelson MR,National Stroke Foundation Stroke Guidelines Expert Working Group.

更新日期：2012-05-01 00:00:00

abstract：:Heart failure remains an ultimately fatal condition that causes significant symptoms as it progresses. The involvement by palliative services in this patient group has been suboptimal despite many years of guidance from international cardiac societies who recommend a palliative focus for these patients. At Hutt hospit...

journal_title：Internal medicine journal

authors： Anscombe R,Middlemiss T

更新日期：2019-03-01 00:00:00

abstract：AIM:To determine diagnostic rate, complications and patient tolerability of endobronchial ultrasound-guide sheath (EBUS-GS) and computed tomography (CT)-guided percutaneous core biopsy for peripheral lung lesions. METHODS:Lesions >1 cm diameter on CT were randomised to either EBUS-GS or CT-guided biopsy. Excluded were...

journal_title：Internal medicine journal

authors： Fielding DI,Chia C,Nguyen P,Bashirzadeh F,Hundloe J,Brown IG,Steinke K

更新日期：2012-08-01 00:00:00