Intravenous immunoglobulins as treatment of severe cutaneous polyarteritis nodosa.

Abstract:

:We describe three patients with severe refractory cutaneous polyarteritis nodosa, resulting in painful ulcers involving the lower limbs and causing toe necrosis. Due to the severity of the cutaneous manifestations, the three patients received intravenous immunoglobulins at a dose of 1 g/kg/day for 2 days monthly. After the second intravenous immunoglobulin infusion, skin signs dramatically improved and completely healed after the third intravenous immunoglobulin infusion. Our findings indicate that intravenous immunoglobulins can be included in a therapeutic strategy to treat refractory cutaneous polyarteritis nodosa.

journal_name

Intern Med J

authors

Marie I,Miranda S,Girszyn N,Soubrane JC,Vandhuick T,Levesque H

doi

10.1111/j.1445-5994.2012.02739.x

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

459-62

issue

4

eissn

1444-0903

issn

1445-5994

journal_volume

42

pub_type

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