Abstract:
:We describe three patients with severe refractory cutaneous polyarteritis nodosa, resulting in painful ulcers involving the lower limbs and causing toe necrosis. Due to the severity of the cutaneous manifestations, the three patients received intravenous immunoglobulins at a dose of 1 g/kg/day for 2 days monthly. After the second intravenous immunoglobulin infusion, skin signs dramatically improved and completely healed after the third intravenous immunoglobulin infusion. Our findings indicate that intravenous immunoglobulins can be included in a therapeutic strategy to treat refractory cutaneous polyarteritis nodosa.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Marie I,Miranda S,Girszyn N,Soubrane JC,Vandhuick T,Levesque Hdoi
10.1111/j.1445-5994.2012.02739.xsubject
Has Abstractpub_date
2012-04-01 00:00:00pages
459-62issue
4eissn
1444-0903issn
1445-5994journal_volume
42pub_type
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journal_title:Internal medicine journal
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