Evaluation of the off-label usage of rituximab in a large teaching hospital in New South Wales.

abstract：BACKGROUND:Circulating antibodies to glutamic acid decarboxylase (GADab) and tyrosine phosphatase-like molecule IA-2 (IA-2ab) are major indicators for auto-immune destruction of pancreatic islet cells. They identify a majority of Caucasians with type 1 diabetes and approximately 50% of Asians, providing evidence of an ...

journal_title：Internal medicine journal

authors： Todd AL,Ng WY,Lui KF,Thai AC

更新日期：2004-01-01 00:00:00

abstract：AIM:To evaluate New Zealand media articles on their coverage of key issues regarding health interventions and whether it is consistent with available evidence. METHODS:A retrospective analysis was carried out of all articles published in five New Zealand media sources over a 6-week period between 15 October and 26 Nov...

journal_title：Internal medicine journal

authors： Robinson C,Cutfield N,Mottershead J,Sharples K,Richards R,Kingan J,Ledgard C,Liyanage A,McLean J,Nahab F,Stewart F,Strachan S,Tucker K,Zhang Z

更新日期：2018-08-01 00:00:00

abstract：:A case of metformin encephalopathy is presented in a patient on haemodialysis for end-stage diabetic renal failure. The patient presented with frequent falls and clinical signs of Parkinsonism, on a background of recent anorexia and significant weight loss. Magnetic resonance imaging showed bilateral, symmetrical abno...

journal_title：Internal medicine journal

authors： McGarvey C,Franconi C,Prentice D,Bynevelt M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The association between the use of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) and mortality in end-stage renal disease (ESRD) patients lacks sufficient evidence. AIM:To investigate the efficacy of ACEI and ARB in ESRD patients. METHODS:This nationwide retrospect...

journal_title：Internal medicine journal

authors： Lee HF,See LC,Chan YH,Yeh YH,Wu LS,Liu JR,Tu HT,Wang CL,Kuo CT,Chang SH

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Neutropenic fever is a medical emergency, which poses a significant morbidity and mortality risk to cancer patients receiving chemotherapy. National guidelines recommend that patients presenting with suspected neutropenic fever receive appropriate intravenous antibiotics within 60 min of admission. AIM:We a...

journal_title：Internal medicine journal

authors： Skiba R,Sikotra N,Ball T,Arellano A,Gabbay E,Clay TD

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:A Resuscitation Plan is a medically authorised order to use or withhold resuscitation interventions. Absence of appropriate resuscitation orders exposes patients to the risk of invasive medical interventions that may be of questionable benefit depending on individual circumstances. AIMS:To describe among ju...

journal_title：Internal medicine journal

authors： Bryant J,Waller A,Pickles R,Hullick C,Price E,White B,Willmott L,Bowman MA,Knight A,Ryall MA,Sanson-Fisher R

更新日期：2020-07-20 00:00:00

abstract：:Mitochondrial DNA (mtDNA) haplogroups are 'neutral polymorphisms' in the mtDNA genome, which have accumulated and persisted along maternal lineages as the human population has migrated worldwide. Three ethnically distinct lineages of human mtDNA populations have been identified: European, characterized by nine haplogr...

journal_title：Internal medicine journal

authors： Manwaring N,Jones MM,Wang JJ,Rochtchina E,Mitchell P,Sue CM

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Patients with established coronary heart disease (CHD) are at the highest risk of further events. Despite proven therapies, secondary prevention is often suboptimal. General practitioners (GPs) are in an ideal position to improve secondary prevention. AIM:To contrast management of cardiovascular risk factor...

journal_title：Internal medicine journal

authors： Driscoll A,Beauchamp A,Lyubomirsky G,Demos L,McNeil J,Tonkin A

更新日期：2011-10-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：:Postvenereal reactive arthritis is an inflammatory form of arthritis that commonly develops after urogenital infection, predominantly in human leucocyte antigen-B27-positive men in the third decade of life. In our hospital, patients underwent synovectomy before a 4-month course of antibiotics (ciprofloxacin, tetracycl...

journal_title：Internal medicine journal

authors： Strelić N,Bojović J,Pavlica L,Cikota-Aleksić B,Miličić B,Magić Z

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The effects of empagliflozin on cardiac structure and function are not known. AIMS:To examine the changes in cardiac structure and function following the addition of empagliflozin in patients with type 2 (T2D) diabetes using cardiac magnetic resonance (CMR) imaging. METHODS:Twenty patients attending a spec...

journal_title：Internal medicine journal

authors： Cohen ND,Gutman SJ,Briganti EM,Taylor AJ

更新日期：2019-08-01 00:00:00

abstract：:Extramedullary haemopoiesis (EMH) is a complication commonly associated with beta-thalassaemia intermedia; it is frequently asymptomatic but can sometimes lead to symptomatic tumour-like masses. No guidelines or common consensus are available in literature regarding the different treatment strategies and only single c...

journal_title：Internal medicine journal

authors： Ruo Redda MG,Allis S,Reali A,Bartoncini S,Roggero S,Anglesio SM,Piga A

更新日期：2014-04-01 00:00:00

abstract：:Staphylococcal infections are a common and significant clinical problem in medical practice. Most strains of Staphylococcus aureus are now resistant to penicillin, and methicillin-resistant strains of S. aureus (MRSA) are common in hospitals and are emerging in the community. Penicillinase-resistant penicillins (flucl...

journal_title：Internal medicine journal

authors： Rayner C,Munckhof WJ

更新日期：2005-12-01 00:00:00

abstract：:Abstract Hyperammonaemic encephalopathy has been infrequently reported after both standard and high-dose chemotherapy for solid and haematological malignancies. It is important to consider this diagnosis for patients with unexplained behaviour changes or encephalopathy and this case report emphasizes this condition an...

journal_title：Internal medicine journal

authors： Nott L,Price TJ,Pittman K,Patterson K,Young R,Fletcher J

更新日期：2008-10-01 00:00:00

abstract：:Climate change is unequivocal. The fourth assessment report of the Intergovermental Panel on Climate Change has recently projected that global average surface temperature will increase by 1.1 to 6.4 degrees C by 2100. Anthropogenic warming during the twenty-first century would be much greater than that observed in the...

journal_title：Internal medicine journal

authors： Tong S,Mackenzie J,Pitman AJ,FitzGerald G,Nicholls N,Selvey L

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Several epidemiological studies have suggested a positive association of coronary heart disease with both Helicobacter pylori and Chlamydia pneumoniae infection. The issue has been difficult to resolve because of the potential impact of several confounding factors, in particular, socioeconomic status for H. ...

journal_title：Internal medicine journal

authors： Fraser AG,Scragg RK,Cox B,Jackson RT

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Polyserositis (PS) is the inflammation, with effusion, of different serous membranes. It has been associated with different aetiologies, but the aetiology of PS remains unknown in a high percentage of patients. AIMS:The general objective of this retrospective study was to analyse the aetiology of PS cases s...

journal_title：Internal medicine journal

authors： Losada I,González-Moreno J,Roda N,Ventayol L,Borjas Y,Domínguez FJ,Fernández-Baca V,García-Gasalla M,Payeras A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) accuracy after neoadjuvant systemic therapy (NST) for breast cancer varies according to hormone receptor (HR), human epidermal growth factor receptor type-2 (HER2) subtype and Ki-67 proliferation index. Whether MRI accuracy varies by genomic signatures is unknown. We examined...

journal_title：Internal medicine journal

authors： Murphy C,Mukaro V,Tobler R,Asher R,Gibbs E,West L,Giuffre B,Baron-Hay S,Khasraw M

更新日期：2018-06-01 00:00:00

abstract：:The Australian Clinical Guidelines for Stroke Management 2010 represents an update of the Clinical Guidelines for Stroke Rehabilitation and Recovery (2005) and the Clinical Guidelines for Acute Stroke Management (2007). For the first time, they cover the whole spectrum of stroke, from public awareness and prehospital ...

journal_title：Internal medicine journal

authors： Wright L,Hill KM,Bernhardt J,Lindley R,Ada L,Bajorek BV,Barber PA,Beer C,Golledge J,Gustafsson L,Hersh D,Kenardy J,Perry L,Middleton S,Brauer SG,Nelson MR,National Stroke Foundation Stroke Guidelines Expert Working Group.

更新日期：2012-05-01 00:00:00

abstract：:Echocardiography is the mainstay of cardiovascular diagnostics, and is the most performed test for the evaluation of cardiac function. Critical and costly management decisions are based on quantification of left ventricular volumes and ejection fraction. Recent advances in echocardiography, such as microsphere contras...

journal_title：Internal medicine journal

authors： Hudaverdi M,Hamilton-Craig C,Platts D,Chan J,Burstow DJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukaemia (CLL) frequently responds to chemoimmunotherapy combining cytotoxic chemotherapy and monoclonal antibodies. However, CLL is associated with significant genetic heterogeneity, and some high-risk forms are known to be chemo-resistant and associated with early relapse. AIMS:To rev...

journal_title：Internal medicine journal

authors： Kuss BJ,Tam CS

更新日期：2017-12-01 00:00:00

abstract：:(Neo)adjuvant chemotherapy for early stage breast cancer is associated with side-effects, resulting in increased emergency department (ED) presentations. Treatment-related toxicity can affect quality of life, compromise chemotherapy delivery and treatment outcomes, and increase healthcare use. We performed a retrospec...

journal_title：Internal medicine journal

authors： Tang M,Horsley P,Lewis CR

更新日期：2018-05-01 00:00:00

abstract：:These consensus guidelines provide recommendations for the safe handling of monoclonal antibodies. Definitive recommendations are given for the minimum safe handling requirements to protect healthcare personnel. The seven recommendations cover: (i) appropriate determinants for evaluating occupational exposure risk; (i...

journal_title：Internal medicine journal

authors： Alexander M,King J,Bajel A,Doecke C,Fox P,Lingaratnam S,Mellor JD,Nicholson L,Roos I,Saunders T,Wilkes J,Zielinski R,Byrne J,MacMillan K,Mollo A,Kirsa S,Green M

更新日期：2014-10-01 00:00:00

abstract：:Many publications have highlighted a lack of practical competencies in recently qualified interns. Consultation between the University of Queensland and the Medical Education Unit at Redcliffe Hospital identified key areas where intervention could lead to greater work readiness, and the development of a complementary ...

journal_title：Internal medicine journal

authors： Costello J,Livett M,Stride PJ,West M,Premaratne M,Thacker D

更新日期：2010-10-01 00:00:00

abstract：:Heart failure remains an ultimately fatal condition that causes significant symptoms as it progresses. The involvement by palliative services in this patient group has been suboptimal despite many years of guidance from international cardiac societies who recommend a palliative focus for these patients. At Hutt hospit...

journal_title：Internal medicine journal

authors： Anscombe R,Middlemiss T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Peptic ulcer disease risk factors have changed, as has the impact of treatment on morbidity and mortality. Recent data on clinical presentation and outcome are sparse in Australia. AIM:To determine the characteristics and outcome of patients presenting with a bleeding peptic ulcer to a tertiary referral cen...

journal_title：Internal medicine journal

authors： Halland M,Young M,Fitzgerald MN,Inder K,Duggan JM,Duggan A

更新日期：2011-08-01 00:00:00

abstract：:Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are an increasingly prescribed class of medication for type 2 diabetes mellitus. Euglycaemic diabetic ketoacidosis (euDKA) has been reported in association with SGLT2i use. Clinicians need to understand how to recognise and treat this complication. We describe three ...

journal_title：Internal medicine journal

authors： Isaacs M,Tonks KT,Greenfield JR

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The clinical significance of extreme hyperferritinaemia has come under scrutiny with the increasing recognition of haemophagocytic lymphohistiocytosis (HLH) in adults. Most studies of hyperferritinaemia have focused on serum ferritin greater than 1000 μg/L, often in ambulatory patients. The conditions associ...

journal_title：Internal medicine journal

authors： Wormsbecker AJ,Sweet DD,Mann SL,Wang SY,Pudek MR,Chen LY

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The reported risk of depression in patients with hypomagnesaemia is controversial. AIM:The objective of this meta-analysis was to assess the association between depression and hypomagnesaemia. METHODS:A literature search was performed using MEDLINE, EMBASE, Cochrane Database and clinicaltrials.gov from inc...

journal_title：Internal medicine journal

authors： Cheungpasitporn W,Thongprayoon C,Mao MA,Srivali N,Ungprasert P,Varothai N,Sanguankeo A,Kittanamongkolchai W,Erickson SB

更新日期：2015-04-01 00:00:00

abstract：:The incidence of tuberculosis in the non-indigenous Australian population is low. However, in this paper we report on three cases of cavitating disease, which seem to be associated with a common illicit drug habit namely smoking marijuana using a makeshift pipe or bong. There was a total of 34 positive contacts of the...

journal_title：Internal medicine journal

authors： Thu K,Hayes M,Miles S,Tierney L,Foy A

更新日期：2013-04-01 00:00:00