Bleeding peptic ulcer: characteristics and outcomes in Newcastle, NSW.

abstract：:Haemophagocytic lymphohistiocytosis (HLH) is rare disorder characterised by immune activation leading to cytokine storm and end-organ failure. It is associated with poor prognosis. HLH is predominantly a disease of early childhood, where it often results from genetic defects that impair cytotoxic function of natural k...

journal_title：Internal medicine journal

authors： Lee WI,Talaulikar D,Cook MC

更新日期：2020-05-10 00:00:00

abstract：BACKGROUND:Poor lung function is a predictor of future all-cause mortality. In Australia, respiratory diseases are particularly prevalent among the indigenous population, especially in remote communities. However, there are little published pulmonary function tests' (PFT) data of remote-based adult indigenous patients....

journal_title：Internal medicine journal

authors： Schubert J,Kruavit A,Mehra S,Wasgewatta S,Chang AB,Heraganahally SS

更新日期：2019-02-01 00:00:00

abstract：:The phenomenon of addiction is complex, although its expression clinically is relatively straightforward. There is a series of neurophysiological changes that mediate changes in the mesolimbic and mesocortical systems which in turn lead to disturbances in reward mechanisms. These then act to perpetuate the cycle of in...

journal_title：Internal medicine journal

authors： Foy A

更新日期：2007-05-01 00:00:00

abstract：:Almost everywhere in the body there are phospholipids, not only comprising the lipid bilayer of membranes, but also in the free state. What is seldom appreciated, except in respirology, is that these 'free' phospholipids are unusual in that many are highly surface active. Surface activity is a property of certain subs...

journal_title：Internal medicine journal

authors： Hills BA

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Circulating antibodies to glutamic acid decarboxylase (GADab) and tyrosine phosphatase-like molecule IA-2 (IA-2ab) are major indicators for auto-immune destruction of pancreatic islet cells. They identify a majority of Caucasians with type 1 diabetes and approximately 50% of Asians, providing evidence of an ...

journal_title：Internal medicine journal

authors： Todd AL,Ng WY,Lui KF,Thai AC

更新日期：2004-01-01 00:00:00

abstract：:Echocardiography is the mainstay of cardiovascular diagnostics, and is the most performed test for the evaluation of cardiac function. Critical and costly management decisions are based on quantification of left ventricular volumes and ejection fraction. Recent advances in echocardiography, such as microsphere contras...

journal_title：Internal medicine journal

authors： Hudaverdi M,Hamilton-Craig C,Platts D,Chan J,Burstow DJ

更新日期：2010-07-01 00:00:00

abstract：:Depression, ischaemic heart disease and cerebrovascular disease are important causes of morbidity and are among the leading contributors to global health burden. These conditions often occur in the same patient, resulting in considerably greater effect on health than combinations of chronic diseases without depression...

journal_title：Internal medicine journal

authors： Ziegelstein RC,Parakh K,Sakhuja A,Bhat U

更新日期：2009-01-01 00:00:00

abstract：:This paper examines the differences between clinical and public health ethics and provides several examples of contemporary public health challenges that pose ethical questions. The relations among ethics, rights and obligations are explored, because public health philosophers propose these as different ways for publi...

journal_title：Internal medicine journal

authors： Leeder SR

更新日期：2004-07-01 00:00:00

abstract：:An acute pulmonary embolism (aPE) is characterised by occlusion of one or more pulmonary arteries. Physiological disturbance may be minimal, but often cardiac output decreases as the right ventricle attempts to overcome increased afterload. Additionally, ventilation-perfusion mismatches can develop in affected vascula...

journal_title：Internal medicine journal

authors： Hepburn-Brown M,Darvall J,Hammerschlag G

更新日期：2019-01-01 00:00:00

abstract：:Radical market-oriented health reforms in New Zealand in the early 1990s failed to deliver key financial targets, resulted in unnecessary patient deaths, adversely affected public healthcare services, induced serious tensions between clinicians and managers and encouraged a predisposition to private healthcare. A more...

journal_title：Internal medicine journal

authors： Nicholls MG,Frampton CM,Bagshaw PF

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Bronchial thermoplasty (BT) is an approved bronchoscopic intervention for the treatment of severe asthma. However, limited published experience exists outside of clinical trials regarding patient selection and outcomes achieved. AIMS:To evaluate the effectiveness and safety of BT in patients with severe ast...

journal_title：Internal medicine journal

authors： Langton D,Sha J,Ing A,Fielding D,Wood E

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:There is a high risk of developing venous thromboembolism (VTE) following total knee arthroplasty (TKA). Conventional thromboprophylactic agents have limitations, such as route of administration, the need for monitoring, narrow therapeutic windows and interactions. Apixaban is a new oral anticoagulant with t...

journal_title：Internal medicine journal

authors： King DA,Pow RE,Dickison DM,Vale PR

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:High inflammatory bowel disease (IBD) rates have been reported in Australasia, but no state-wide studies have yet been performed. AIM:This study estimates the 1-year incidence and point prevalence of IBD in the state of Tasmania, Australia. It also reports clinical outcomes after 12 months of diagnosis in a...

journal_title：Internal medicine journal

authors： Bhatia R,Yeoh SW,Vaz K,Studd C,Wilson J,Bell S,Otahal P,Venn A

更新日期：2019-05-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...

journal_title：Internal medicine journal

authors： Finlayson J,Grey D,Kavanagh L,Witt C

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The 2001 National Health and Medical Research Council/Australasian Society of Blood Transfusion Clinical Practice Guidelines for cryoprecipitate are being updated, and cryoprecipitate has been incorporated into new Patient Blood Management modules. AIMS:This clinical audit sought to clarify current cryoprec...

journal_title：Internal medicine journal

authors： Anderson MA,Glazebrook B,Cutts B,Stevenson L,Bielby L,Borosak M

更新日期：2013-08-01 00:00:00

abstract：:Postvenereal reactive arthritis is an inflammatory form of arthritis that commonly develops after urogenital infection, predominantly in human leucocyte antigen-B27-positive men in the third decade of life. In our hospital, patients underwent synovectomy before a 4-month course of antibiotics (ciprofloxacin, tetracycl...

journal_title：Internal medicine journal

authors： Strelić N,Bojović J,Pavlica L,Cikota-Aleksić B,Miličić B,Magić Z

更新日期：2014-12-01 00:00:00

abstract：:Growth hormone (GH) replacement therapy was recently recommended by the Pharmaceutical Benefits Advisory Committee (PBAC) for listing on the Pharmaceutical Benefits Scheme for adults with severe GH deficiency and impaired quality of life. This approval was significant for two reasons. First, the application was initia...

journal_title：Internal medicine journal

authors： Lipworth W,Ambler G,Burt MG,Fairchild J,Inder WJ,Werther G,Ho K

更新日期：2018-08-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a rare disease affecting women, classically involving the lungs. However, extrapulmonary manifestations also occur, including renal angiomyolipomas, retroperitoneal lymphangioleiomyomas and extrathoracic lymphadenopathy. The lung disease is hormone-responsive, but no information exist...

journal_title：Internal medicine journal

authors： Sandrini A,Silverstone E,Yates DH

更新日期：2011-12-01 00:00:00

abstract：:There is evidence of the increasing use of complementary and alternative medicine by Australians diagnosed with cancer. Given the increasing desire of cancer patients to use complementary and alternative medicine, it is important that clinicians have a good understanding of the evidence available in this field. This c...

journal_title：Internal medicine journal

authors： Joske DJ,Rao A,Kristjanson L

更新日期：2006-09-01 00:00:00

abstract：:Clinician-performed chest ultrasound is rapidly entering clinical practice in the fields of intensive care, respiratory medicine and acute medicine. Ultrasound is clearly useful in the diagnosis and characterisation of pleural diseases. It is also critical in improving the safety of pleural interventions. More recentl...

journal_title：Internal medicine journal

authors： Hew M,Heinze S

更新日期：2012-08-01 00:00:00

abstract：:Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...

journal_title：Internal medicine journal

authors： Kaazan P,Tan Z,Bednarz J,Hughes J,Grafton R,Andrews JM

更新日期：2020-09-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:  Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...

journal_title：Internal medicine journal

authors： Keogh A,Strange G,Kotlyar E,Williams T,Kilpatrick D,Macdonald P,Brown K,Pidoux A,Kermeen F,Steele P,Dalton B,Gabbay E

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Prothrombinex-VF (a three-factor prothrombin complex concentrate) contains little factor VII. Therefore, the Warfarin Reversal Consensus Guidelines from 2004 published by The Australasian Society of Haemostasis and Thrombosis recommend that it be administered with fresh frozen plasma to reverse warfarin anti...

journal_title：Internal medicine journal

authors： Tran H,Collecutt M,Whitehead S,Salem HH

更新日期：2011-04-01 00:00:00

abstract：AIM:To carry out an audit of the appropriateness of fresh-frozen plasma (FFP) and platelets (Plt) transfusion with reference to the Australian National Health and Medical Research Council/Australian Society of Blood Transfusion Clinical Practice Guidelines, and to assess the impact of a self-educating transfusion reque...

journal_title：Internal medicine journal

authors： Hui CH,Williams I,Davis K

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Poor sleep is common after stroke, and data regarding its effect on rehabilitation outcomes are limited. Controversial evidence was found concerning the effect of sedatives on improving sleep quality in poor sleepers after stroke. AIM:To assess the prevalence of poor sleep in post-stroke patients and its ef...

journal_title：Internal medicine journal

authors： Iddagoda MT,Inderjeeth CA,Chan K,Raymond WD

更新日期：2020-02-01 00:00:00

abstract：:There is accumulating evidence that point-of-care delivery of clinical information such as evidence-based medicine, practice guidelines and drug information can streamline clinical practice and reduce preventable errors. In Australia, hospital-based physicians have -generally been slow to fully use these resources to ...

journal_title：Internal medicine journal

authors： Wilcox RA,Whitham EM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...

journal_title：Internal medicine journal

authors： Bradstock KF,Hertzberg MS,Kerridge IH,Svennilson J,McGurgan M,Huang G,Antonenas V,Gottlieb DJ

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Increasing numbers of patients receiving new oral anticoagulants (NOAC) are undergoing elective surgery. The extent to which perioperative interruption of NOAC therapy and use of bridging heparin are concordant with best evidence is uncertain. AIMS:To determine: (i) concordance of NOAC and bridging heparin ...

journal_title：Internal medicine journal

authors： Wamala H,Scott IA,Caney X

更新日期：2017-12-01 00:00:00

abstract：:As the mortality rate from breast cancer decreases, the issues facing breast cancer survivors are becoming increasingly important. Survivors of all ages may face physical and psychosocial consequences of their diagnosis and treatments. However, the long-term fertility and menopause-related side-effects of adjuvant the...

journal_title：Internal medicine journal

authors： Friedlander M,Thewes B

更新日期：2003-08-01 00:00:00