Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation.

abstract：BACKGROUND:Lung cancer accounts for significant morbidity and mortality worldwide. The effect of recent changes in demographics and management on outcomes in Australia has not been clearly defined. AIMS:To compare three consecutive lung cancer cohorts to evaluate emergent differences in diagnosis, management and morta...

journal_title：Internal medicine journal

authors： Denton EJ,Hart D,Wainer Z,Wright G,Russell PA,Conron M

更新日期：2016-08-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...

journal_title：Internal medicine journal

authors： Finlayson J,Grey D,Kavanagh L,Witt C

更新日期：2011-08-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) haplogroups are 'neutral polymorphisms' in the mtDNA genome, which have accumulated and persisted along maternal lineages as the human population has migrated worldwide. Three ethnically distinct lineages of human mtDNA populations have been identified: European, characterized by nine haplogr...

journal_title：Internal medicine journal

authors： Manwaring N,Jones MM,Wang JJ,Rochtchina E,Mitchell P,Sue CM

更新日期：2006-08-01 00:00:00

abstract：AIM:To carry out an audit of the appropriateness of fresh-frozen plasma (FFP) and platelets (Plt) transfusion with reference to the Australian National Health and Medical Research Council/Australian Society of Blood Transfusion Clinical Practice Guidelines, and to assess the impact of a self-educating transfusion reque...

journal_title：Internal medicine journal

authors： Hui CH,Williams I,Davis K

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:We presumed that identification of the factors associated with improvement of fatty livers disease (FLD) would support the therapeutic options for FLD. The goal of this study was to clarify what clinical characteristics are associated with biochemical and sonographic improvements in the non-alcoholic populat...

journal_title：Internal medicine journal

authors： Park SH,Kim BI,Kim HJ,Kim H,Kim SH,Park DI,Cho YK,Sung IK,Sohn CI,Jeon WK,Keum DK

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND/AIM:Although induction chemotherapy comprising high-dose cytarabine (HiDAC) in combination with idarubicin and etoposide or 'ICE' for adult acute myeloid leukaemia (AML) produces a complete remission rate of nearly 80%, gastrointestinal toxicity is significant. Omission of etoposide may produce similar clini...

journal_title：Internal medicine journal

authors： Low M,Lee D,Coutsouvelis J,Patil S,Opat S,Walker P,Schwarer A,Salem H,Avery S,Spencer A,Wei A

更新日期：2013-03-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：:Cardiac involvement is not regarded as a feature of Henoch-Schönlein purpura (HSP). We report a patient with HSP who developed significant cardiac symptoms, which resolved with immunosuppression. We review previous cases of HSP with cardiac features, none of which showed a response to treatment, and discuss evidence t...

journal_title：Internal medicine journal

authors： Polizzotto MN,Gibbs SD,Beswick W,Seymour JF

更新日期：2006-05-01 00:00:00

abstract：AIM:Bigge Park Centre (BPC) is a sexual health clinic located in a socially disadvantaged area in Southwest Sydney. This served as a retrospective clinical audit, documenting patient demographics, identifying factors associated with virological, immunological and discordant responses, evaluating the centre's ability in...

journal_title：Internal medicine journal

authors： Hsu DC,Quin JW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Guidelines recommend screening for strongyloidiasis prior to immunosuppression in those at epidemiological risk, as hyperinfection following immunosuppression is often fatal. The uptake of this recommendation is unknown, and we aimed to explore this in our setting. AIMS:Determine the proportion of adult pat...

journal_title：Internal medicine journal

authors： Muhi S,Ko DK,McGuinness SL,Biggs BA,Mahanty S,Delany C

更新日期：2020-07-20 00:00:00

abstract：:Prior randomised studies of immunoglobulin replacement therapy have studied mixed populations with or without a history of infections. Immunoglobulin therapy is expensive and in limited supply suggesting that optimising patient selection is of value. In this retrospective study, infection history identified high-risk ...

journal_title：Internal medicine journal

authors： Paxton L,Hawkins C,Crispin P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Peptide receptor radionuclide therapy with 177 Lu-DOTATATE is a promising treatment for inoperable or metastatic neuroendocrine tumours (NET). In 2015, the NSW Ministry of Health provided funding for 177 Lu-DOTATATE treatment of NET under an evaluation framework. AIMS:To examine the safety and outcomes of N...

journal_title：Internal medicine journal

authors： Lin E,Chen T,Little A,Holliday L,Roach P,Butler P,Hosking E,Bailey E,Elison B,Currow D

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The elderly obese are at increased risk of mortality and morbidity of many obesity-related chronic diseases, such as hypertension, diabetes and coronary heart disease. This study was designed to investigate the epidemiological features of overweight and obesity in older rural Chinese. METHODS:A cross-sectio...

journal_title：Internal medicine journal

authors： Zhang X,Sun Z,Zhang X,Zheng L,Liu S,Xu C,Li J,Zhao F,Li J,Hu D,Sun Y

更新日期：2008-07-01 00:00:00

abstract：AIMS:Low molecular weight heparins (LMWH) permit safe and effective treatment of uncomplicated deep venous thrombosis (DVT) at home. The aim of this study was to evaluate the cost minimization, cost shifting and patient satisfaction associated with at-home DVT treatment using the LMWH enoxaparin, compared to standard i...

journal_title：Internal medicine journal

authors： Smith BJ,Weekley JS,Pilotto L,Howe T,Beven R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:There is no mechanism in place for monitoring or quality improvement of cancer multidisciplinary meetings (MDM) in Australia. AIM:To develop a peer-review process for quality improvement of MDM. METHODS:This project involved three phases: (i) development of a draft peer-review framework, supporting documen...

journal_title：Internal medicine journal

authors： Johnson CE,Slavova-Azmanova N,Saunders C

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Physician trainees have elevated rates of psychological distress, mental disorders and suicide. Physician supervisors can support the mental health needs of trainees. AIM:To test the feasibility and acceptability of a tailored online mental health training program and ascertain the potential effectiveness o...

journal_title：Internal medicine journal

authors： Gayed A,Kugenthiran N,LaMontagne AD,Christensen H,Glozier N,Harvey SB

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:As direct-to-consumer personal genome testing (DTC-PGT) is increasingly available in Australia, knowledge of Australians' perceptions and attitudes towards this technology is needed in order to assess the (potential) impact it might have on the Australian public and healthcare system. AIMS:To explore the kn...

journal_title：Internal medicine journal

authors： Savard J,Mooney-Somers J,Newson AJ,Kerridge I

更新日期：2014-01-01 00:00:00

abstract：:The insulin tolerance test is considered the gold standard for assessing the hypothalamic-pituitary-adrenal and growth hormone (GH) axes, but its use varies considerably among different endocrine units. We recommend using the insulin tolerance test to assess the hypothalamic-pituitary-adrenal axis within 3 months of p...

journal_title：Internal medicine journal

authors： Sarlos S,Inder WJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Many patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have type 2 respiratory failure (T2RF). Often arterial blood gases are not performed and correlation with venous blood gases (VBG) is controversial. The venous pH and bicarbonate (HCO3 ) are useful, but VBG pCO2 (PvCO2 )...

journal_title：Internal medicine journal

authors： Wong EKC,Lee PCS,Ansary S,Asha S,Wong KKH,Yee BJ,Ng AT

更新日期：2019-07-01 00:00:00

abstract：:The differential diagnosis of Parkinsonian syndromes is challenging, especially in the elderly as they often have complex presentations. Nuclear imaging modalities can increase diagnostic accuracy. Single-photon emission tomography (SPECT) using the ligand (99m Tc)-TRODAT-1 is used overseas but is yet to be approved i...

journal_title：Internal medicine journal

authors： Wong D,Veitch P,Schembri G

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Inequalities in access to renal services and acute care for rural and remote populations in Australia have been described but not quantified. AIM:To describe: the coverage of renal disease management services in rural and remote Australia; and the characteristics of patients who had an aeromedical retrieval...

journal_title：Internal medicine journal

authors： Gardiner FW,Bishop L,Gale L,Harwood A,Teoh N,Lucas RM,Jones M,Laverty M

更新日期：2020-08-01 00:00:00

abstract：AIMS:The aim of this study was to provide the first population-based descriptions of typical sleep duration and the prevalence of chronic sleep restriction and chronic sleepiness in community-dwelling Australian adults. METHODS:Ten thousand subjects randomly selected from the New South Wales electoral roll, half aged ...

journal_title：Internal medicine journal

authors： Bartlett DJ,Marshall NS,Williams A,Grunstein RR

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:High baseline level of soluble suppression of tumourigenicity 2 (sST2) was an independent predictor of cardiovascular death and heart failure in ST-segment elevation myocardial infarction (STEMI). AIMS:To investigate the value of serum sST2 baseline levels in predicting myocardial reperfusion in patients wi...

journal_title：Internal medicine journal

authors： Bai S,Liu H,Wu H,Wang X,Li R,Li X,Li X,Zhang L,Chen T,Du R

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is a newly recognised condition that is apparently increasing in prevalence, and the aetiology is poorly understood. The role of aeroallergens in EoE is controversial, given the success of dietary therapy. Massive aeroallergen exposure leading to food bolus obstruction events (...

journal_title：Internal medicine journal

authors： Philpott HL,Nandurkar S,Thien F,Bloom S,Lin E,Goldberg R,Boyapati R,Finch A,Royce SG,Gibson PR

更新日期：2015-09-01 00:00:00

abstract：:Non-invasive ventilation refers to a number of respiratory support strategies commonly used in critical care settings. This paper describes the principles of non-invasive ventilation, the practicalities of its use and the evidence for its use in a number of common acute conditions. ...

journal_title：Internal medicine journal

authors： Cross AM

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemoradiation therapy (CRT) is standard of care treatment for locally advanced rectal cancer (LARC). A pathologic complete response (pCR) following CRT is an early indicator of treatment benefit and associated with excellent survival outcomes. As capecitabine replaces infusional 5-fluorouracil (...

journal_title：Internal medicine journal

authors： Loft M,Wong HL,Kosmider S,Lee M,Tie J,Wong R,Jones IT,Croxford M,Steel M,Faragher I,Guerrieri M,Christie M,Gibbs P

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND:Many studies support the role of bilirubin as a cytoprotector in chronic inflammatory diseases, such as stroke and atherosclerosis. AIM:To investigate the relationship between serum total bilirubin levels and functional dependence in older adults. METHODS:Data from the National Health and Nutrition Examina...

journal_title：Internal medicine journal

authors： Kao TW,Chou CH,Wang CC,Chou CC,Hu J,Chen WL

更新日期：2012-11-01 00:00:00

abstract：:The move by the Medical Board of Australia to commence a conversation with the medical profession about revalidation reflects that patient-centred care is at the heart of good medical practice. Patients judge their doctors' commitment to them based on whether their individual interactions with doctors meet their needs...

journal_title：Internal medicine journal

authors： Phelps G,Dalton S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Poor lung function is a predictor of future all-cause mortality. In Australia, respiratory diseases are particularly prevalent among the indigenous population, especially in remote communities. However, there are little published pulmonary function tests' (PFT) data of remote-based adult indigenous patients....

journal_title：Internal medicine journal

authors： Schubert J,Kruavit A,Mehra S,Wasgewatta S,Chang AB,Heraganahally SS

更新日期：2019-02-01 00:00:00