Selective use of the insulin tolerance test to diagnose hypopituitarism.

Abstract:

:The insulin tolerance test is considered the gold standard for assessing the hypothalamic-pituitary-adrenal and growth hormone (GH) axes, but its use varies considerably among different endocrine units. We recommend using the insulin tolerance test to assess the hypothalamic-pituitary-adrenal axis within 3 months of pituitary surgery, where adrenocorticotropic hormone 1-24 testing is equivocal, and to assess for GH deficiency where the patient is being considered for GH replacement therapy. We also discuss safety issues, how to ensure adequate hypoglycaemia and possible alternative tests, such as the overnight metyrapone test and glucagon test.

journal_name

Intern Med J

authors

Sarlos S,Inder WJ

doi

10.1111/imj.12011

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

89-93

issue

1

eissn

1444-0903

issn

1445-5994

journal_volume

43

pub_type

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