Antifungal prophylaxis in adult stem cell transplantation and haematological malignancy.

abstract：:Vancomycin remains a clinically useful antibiotic despite the advent of several alternative drugs. Optimising vancomycin therapy with therapeutic drug monitoring is widely recommended. The aim of therapeutic drug monitoring is to help the clinician to achieve target pharmacodynamic parameters in the case of vancomycin...

journal_title：Internal medicine journal

authors： Avent ML,Vaska VL,Rogers BA,Cheng AC,van Hal SJ,Holmes NE,Howden BP,Paterson DL

更新日期：2013-02-01 00:00:00

abstract：:There is accumulating evidence that point-of-care delivery of clinical information such as evidence-based medicine, practice guidelines and drug information can streamline clinical practice and reduce preventable errors. In Australia, hospital-based physicians have -generally been slow to fully use these resources to ...

journal_title：Internal medicine journal

authors： Wilcox RA,Whitham EM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:  According to the International Prognostic Scoring System (IPSS), sole +8 is categorized as intermediate cytogenetic subgroup. But as some myelodysplastic syndrome (MDS) patients with +8 perhaps progress quickly to acute leukaemia and have shorter survival, some reports have suggested that +8 should be cate...

journal_title：Internal medicine journal

authors： Ma Y,Wang X,Xu X,Lin G

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The rate of hospital admissions for cirrhosis increased 1.3-fold during 2008-2016 in Queensland. Alcohol misuse was a contributing factor for cirrhosis in 55% of admissions and 40% of patients had at least one comorbidity. AIM:This paper examines the temporal change in aetiology of liver disease and presenc...

journal_title：Internal medicine journal

authors： Valery PC,McPhail S,Stuart KA,Hartel G,Clark PJ,O'Beirne J,Skoien R,Rahman T,Moser C,Powell EE

更新日期：2020-02-25 00:00:00

abstract：:Clarithromycin is the most documented cytochrome P450 3A4 (CYP3A4) inhibitor to cause an adverse interaction with simvastatin. This particular case is of interest as rhabdomyolysis only occurred after an increase in the dose of clarithromycin. The patient developed raised cardiac biomarkers without any obvious cardiac...

journal_title：Internal medicine journal

authors： Page SR,Yee KC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND/AIM:Few studies have specifically investigated treatment of prednisolone-induced hyperglycaemia. AIM:To determine if a basal bolus insulin (BBI) protocol for inpatient hyperglycaemia is effective in patients prescribed acute prednisolone for an inflammatory disease. METHODS:In a cross-sectional study, 66 p...

journal_title：Internal medicine journal

authors： Burt MG,Drake SM,Aguilar-Loza NR,Esterman A,Stranks SN,Roberts GW

更新日期：2015-03-01 00:00:00

abstract：:Depression is the leading cause of non-fatal disease burden in Australia. Recently, increasing public recognition, together with the development of more integrated medical and psychological healthcare services has resulted in significant improvements. New pathophysiological models incorporate structural brain changes ...

journal_title：Internal medicine journal

authors： Hickie IB,Naismith SL,Norrie LM,Scott EM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:  Hepatic epithelioid haemangioendothelioma (HEH) is a rare, low grade malignant neoplasm of endothelial origin which is difficult to diagnose and has a variable outcome. We review five HEH cases from our centre with the aim of identifying clinical predictors of outcome and various therapeutic options. METH...

journal_title：Internal medicine journal

authors： Thin LW,Wong DD,De Boer BW,Ferguson JM,Adams L,Macquillan G,Delriviere L,Mitchell A,Jeffrey GP

更新日期：2010-10-01 00:00:00

abstract：:Haemophagocytic lymphohistiocytosis (HLH) is rare disorder characterised by immune activation leading to cytokine storm and end-organ failure. It is associated with poor prognosis. HLH is predominantly a disease of early childhood, where it often results from genetic defects that impair cytotoxic function of natural k...

journal_title：Internal medicine journal

authors： Lee WI,Talaulikar D,Cook MC

更新日期：2020-05-10 00:00:00

abstract：BACKGROUND:Anticipating the prospect of specific treatment, we studied a large group of Australians with Fabry's disease. AIMS:We aimed to: (i) document the clinical features of Fabry's disease in Australian patients, (ii) test the hypothesis that clinical features vary with specific mutation and blood group and (iii)...

journal_title：Internal medicine journal

authors： Galanos J,Nicholls K,Grigg L,Kiers L,Crawford A,Becker G

更新日期：2002-12-01 00:00:00

abstract：:A prospective study of non-invasive ventilation at The Prince Charles Hospital outside of the intensive care unit from March 2015 to March 2016 was performed. Overall 69 patients were included. Acute hypercapnic respiratory failure was the most common indication (n = 59; 85%). 49 (71%) had multifactorial respiratory f...

journal_title：Internal medicine journal

authors： Smith DB,Tay GTP,Hay K,Antony J,Bell B,Kinnear FB,Curtin DL,Douglas J

更新日期：2017-12-01 00:00:00

abstract：:Extramedullary haemopoiesis (EMH) is a complication commonly associated with beta-thalassaemia intermedia; it is frequently asymptomatic but can sometimes lead to symptomatic tumour-like masses. No guidelines or common consensus are available in literature regarding the different treatment strategies and only single c...

journal_title：Internal medicine journal

authors： Ruo Redda MG,Allis S,Reali A,Bartoncini S,Roggero S,Anglesio SM,Piga A

更新日期：2014-04-01 00:00:00

abstract：:Previously, management of hypertension has concentrated on lowering elevated blood pressure. However, the target has shifted to reducing absolute cardiovascular (CV) risk. It is estimated that two in three Australian adults have three or more CV risk factors at the same time. Moderate reductions in several risk factor...

journal_title：Internal medicine journal

authors： Sindone A,Erlich J,Lee C,Newman H,Suranyi M,Roger SD

更新日期：2016-03-01 00:00:00

abstract：:Radical market-oriented health reforms in New Zealand in the early 1990s failed to deliver key financial targets, resulted in unnecessary patient deaths, adversely affected public healthcare services, induced serious tensions between clinicians and managers and encouraged a predisposition to private healthcare. A more...

journal_title：Internal medicine journal

authors： Nicholls MG,Frampton CM,Bagshaw PF

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Anticoagulants are recommended to prevent cardioembolic stroke in most patients with atrial fibrillation (AF). Management errors with anticoagulation and use of aspirin instead of anticoagulants have been documented worldwide, especially with vitamin K antagonists. We assessed the rate of anticoagul...

journal_title：Internal medicine journal

authors： Wong E,Aaqib M,Thijs V

更新日期：2020-12-21 00:00:00

abstract：:Mechanical ventilation as a resource is limited and may lead to poor outcomes in at-risk populations. Critical care supports may not be preferred by those at risk of deterioration in the COVID-19 setting. Patient-centred communication and shared decision-making should continue to remain central to clinical practice. ...

journal_title：Internal medicine journal

authors： Simpson N,Milnes S,Steinfort D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND/AIM:In patients discharged from an Older Person's Health hospital, we assessed (i) the prevalence of anticholinergic medications (ACM) in this study population and (ii) changes in anticholinergic drug burden during admission using the Anticholinergic Drug Scale (ADS). METHODS:Cases were identified between S...

journal_title：Internal medicine journal

authors： Lee MSS,Hanger HC

更新日期：2017-06-01 00:00:00

abstract：:Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...

journal_title：Internal medicine journal

authors： Chen BS,Wong SHC,Hawkins S,Huggins L

更新日期：2018-12-01 00:00:00

abstract：:This article reports the findings of a survey developed to assess the current use of antifungal prophylaxis among haematology and infectious disease clinicians across Australia and New Zealand, and their alignment with existing consensus guidelines for the use of antifungal agents in the haematology/oncology setting (...

journal_title：Internal medicine journal

authors： van Hal SJ,Gilroy NM,Morrissey CO,Worth LJ,Szer J,Tam CS,Chen SC,Thursky KA,Slavin MA

更新日期：2014-12-01 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：:Minimisation of radiation exposure with cardiac imaging reduces the potential of secondary side effects. Radiation exposure from myocardial perfusion scintigraphy and computed tomography coronary angiography (CTCA) was compared. Overall doses were low with both modalities. Doses were lower in the CTCA group, but by on...

journal_title：Internal medicine journal

authors： Tsay IM,Subiakto I,Asrar Ul Haq M,Castles AV,Allman K,Hayat U,Rudd N,Barlis P,van Gaal W

更新日期：2016-02-01 00:00:00

abstract：:It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...

journal_title：Internal medicine journal

authors： Tang ML,Mullins RJ

更新日期：2017-03-01 00:00:00

abstract：:Cardiac involvement is not regarded as a feature of Henoch-Schönlein purpura (HSP). We report a patient with HSP who developed significant cardiac symptoms, which resolved with immunosuppression. We review previous cases of HSP with cardiac features, none of which showed a response to treatment, and discuss evidence t...

journal_title：Internal medicine journal

authors： Polizzotto MN,Gibbs SD,Beswick W,Seymour JF

更新日期：2006-05-01 00:00:00

abstract：:The adverse fallout following the Royal Australasian College of Physician's (RACP) introduction to computer-based testing that was disrupted in the February 2018 examinations, aroused great sympathy for the candidates and perhaps rekindled worrying memories by the College fellowship. The RACP's entrance procedures hav...

journal_title：Internal medicine journal

authors： H Short B

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:There is little existing research on the role that secondary care letters have in ensuring patient understanding of chronic health conditions. AIM:To determine whether minimising the use of medical terminology in medical correspondence improved patient understanding and anxiety/depression scores. METHODS:A...

journal_title：Internal medicine journal

authors： Wernick M,Hale P,Anticich N,Busch S,Merriman L,King B,Pegg T

更新日期：2016-05-01 00:00:00

abstract：:The antibiotic optimisation imperative is now ubiquitous, with national policy frameworks in Organisation for Economic Co-operation and Development (OECD) countries incorporating the requirement for antimicrobial stewardship within healthcare services. Yet in practice, the optimisation agenda often raises complex ethi...

journal_title：Internal medicine journal

authors： Broom J,Broom A,Good P,Lwin Z

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHOD...

journal_title：Internal medicine journal

authors： Thomas MG,Morris AJ

更新日期：2005-06-01 00:00:00

abstract：AIMS:We sought to assess a broad array of possible precipitants of acute coronary syndromes (ACS) and evaluate their association with detectable inflammatory activation. METHODS AND RESULTS:Within a case-crossover design, using a standardised questionnaire, interviews among 348 ST-elevation myocardial infarction (44%)...

journal_title：Internal medicine journal

authors： Chew DP,Mattschoss S,Horsfall M,Astley C,Vaile JC,Joseph MX

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Patients who suffer from acute IgE-mediated allergy to a cephalosporin antibiotic are frequently assumed to be at high risk of allergy to other cephalosporins and penicillins. AIM:To define cross-reactivity patterns in patients with confirmed allergy to a cephalosporin. METHODS:Subjects presenting with a h...

journal_title：Internal medicine journal

authors： Yuson C,Kumar K,Le A,Ahmadie A,Banovic T,Heddle R,Kette F,Smith W,Hissaria P

更新日期：2019-08-01 00:00:00