Audit of anticholinergic medication changes in older hospitalised patients using the Anticholinergic Drug Scale.

abstract：:Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are an increasingly prescribed class of medication for type 2 diabetes mellitus. Euglycaemic diabetic ketoacidosis (euDKA) has been reported in association with SGLT2i use. Clinicians need to understand how to recognise and treat this complication. We describe three ...

journal_title：Internal medicine journal

authors： Isaacs M,Tonks KT,Greenfield JR

更新日期：2017-06-01 00:00:00

abstract：AIMS:To assess the level of evidence-based drug prescribing for acute coronary syndrome (ACS) at discharge from Western Australian (WA) hospitals and determine predictors of such prescribing in Aboriginal and non-Aboriginal patients. METHODS:All Aboriginal (2002-2004) and a random sample of non-Aboriginal (2003) hospi...

journal_title：Internal medicine journal

authors： Gausia K,Katzenellenbogen JM,Sanfilippo FM,Knuiman MW,Thompson PL,Hobbs MS,Thompson SC

更新日期：2014-04-01 00:00:00

abstract：AIM:To prospectively evaluate the efficacy and safety of Selective Internal Radiation (SIR) Spheres (Sirtex Medical, Sydney, NSW, Australia) in patients with unresectable primary or secondary hepatic malignancies. METHODS:We report our experience of SIR sphere therapy at three Australian centres. Patients with previou...

journal_title：Internal medicine journal

authors： Lim L,Gibbs P,Yip D,Shapiro JD,Dowling R,Smith D,Little A,Bailey W,Liechtenstein M

更新日期：2005-04-01 00:00:00

abstract：:Previously, management of hypertension has concentrated on lowering elevated blood pressure. However, the target has shifted to reducing absolute cardiovascular (CV) risk. It is estimated that two in three Australian adults have three or more CV risk factors at the same time. Moderate reductions in several risk factor...

journal_title：Internal medicine journal

authors： Sindone A,Erlich J,Lee C,Newman H,Suranyi M,Roger SD

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Peptide receptor radionuclide therapy with 177 Lu-DOTATATE is a promising treatment for inoperable or metastatic neuroendocrine tumours (NET). In 2015, the NSW Ministry of Health provided funding for 177 Lu-DOTATATE treatment of NET under an evaluation framework. AIMS:To examine the safety and outcomes of N...

journal_title：Internal medicine journal

authors： Lin E,Chen T,Little A,Holliday L,Roach P,Butler P,Hosking E,Bailey E,Elison B,Currow D

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Clopidogrel is an antiplatelet drug increasingly used in the secondary prevention of atherosclerotic vascular events. Compared with aspirin, clopidogrel has marginal additional efficacy and similar safety, but carries a substantial price premium. It remains unclear whether its use is cost-effective. AIMS:(i...

journal_title：Internal medicine journal

authors： Kubler PA,Pillans PI,Marrinan MC,Frogley M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The elderly obese are at increased risk of mortality and morbidity of many obesity-related chronic diseases, such as hypertension, diabetes and coronary heart disease. This study was designed to investigate the epidemiological features of overweight and obesity in older rural Chinese. METHODS:A cross-sectio...

journal_title：Internal medicine journal

authors： Zhang X,Sun Z,Zhang X,Zheng L,Liu S,Xu C,Li J,Zhao F,Li J,Hu D,Sun Y

更新日期：2008-07-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Teaching, mentoring and supervision (TMS) are fundamental skills with a specific commitment within the Royal Australasian College of Physicians (RACP) professional practice framework. The new basic training standards include 'use of appropriate educational techniques to facilitate the learning of peers, juni...

journal_title：Internal medicine journal

authors： Chapman L,Mysko C,Coombridge H

更新日期：2020-06-08 00:00:00

abstract：AIMS:To measure factors associated with underuse of beta-blocker therapy after myocardial infarction (MI). METHODS:The Newcastle and Perth collaborating centres of the World Health Organization (WHO) MONICA project (to MONItor trends and determinants of Cardiovascular disease) systematically evaluated all patients adm...

journal_title：Internal medicine journal

authors： Nicholls SJ,McElduff P,Dobson AJ,Jamrozik KD,Hobbs MS,Leitch JW

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Effective tuberculosis (TB) control relies on early diagnosis and prompt treatment commencement. AIM:To investigate delays in presentation and diagnosis of pulmonary TB (PTB) in a low incidence setting in Western Melbourne. METHODS:A single-centred retrospective observational cohort study of symptomatic pa...

journal_title：Internal medicine journal

authors： Williams E,Cheng AC,Lane GP,Guy SD

更新日期：2018-02-01 00:00:00

abstract：:Heart failure remains an ultimately fatal condition that causes significant symptoms as it progresses. The involvement by palliative services in this patient group has been suboptimal despite many years of guidance from international cardiac societies who recommend a palliative focus for these patients. At Hutt hospit...

journal_title：Internal medicine journal

authors： Anscombe R,Middlemiss T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:In Australia medical practitioners are often required to assume the responsibility for assessing fitness to drive. However the clinical practice, knowledge and attitudes of doctors with regards to this responsibility are unknown. The aim of this study was to determine the clinical practice, knowledge and att...

journal_title：Internal medicine journal

authors： Shanahan EM,Sladek RM,Phillips P

更新日期：2007-06-01 00:00:00

abstract：:5-aminosalicylates (5-ASA) remain an important strategy in the induction and maintenance of remission of inflammatory bowel diseases especially in ulcerative colitis. The prototypical drug of this class, sulfasalazine is generally well tolerated with severe hypersensitivity reactions and hepatotoxicity also described ...

journal_title：Internal medicine journal

authors： Kong LM,Fok KC,Tsui A,Qian C,Fisher L

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Immunohistochemistry for loss of expression of one or more of the mismatch repair proteins is performed on colorectal cancer tissue as a screening test for Lynch syndrome; however, its role in pre-malignant polyps remains controversial. AIM:To determine the effectiveness of mismatch repair immunohistochemis...

journal_title：Internal medicine journal

authors： Dow E,Buchanan DD,Winship IM

更新日期：2018-11-01 00:00:00

abstract：:Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...

journal_title：Internal medicine journal

authors： Chen BS,Wong SHC,Hawkins S,Huggins L

更新日期：2018-12-01 00:00:00

abstract：:Previous reports have noted an association between membranous nephropathy and focal segmental glomerulosclerosis with Guillain-Barre syndrome. We report a case of Campylobacter enteritis, which was complicated by both focal segmental glomerulosclerosis of the collapsing variety and Guillain-Barre syndrome, and propose...

journal_title：Internal medicine journal

authors： Lim A,Lydia A,Rim H,Dowling J,Kerr P

更新日期：2007-10-01 00:00:00

abstract：:This article reports the findings of a survey developed to assess the current use of antifungal prophylaxis among haematology and infectious disease clinicians across Australia and New Zealand, and their alignment with existing consensus guidelines for the use of antifungal agents in the haematology/oncology setting (...

journal_title：Internal medicine journal

authors： van Hal SJ,Gilroy NM,Morrissey CO,Worth LJ,Szer J,Tam CS,Chen SC,Thursky KA,Slavin MA

更新日期：2014-12-01 00:00:00

abstract：:Diabetes can lead to a myriad of microvascular and macrovascular complications - with the leading cause of mortality in diabetes being cardiovascular disease. Low-density lipoprotein cholesterol, along with non-high-density lipoprotein cholesterol and triglycerides are proven, modifiable risk factors for cardiovascula...

journal_title：Internal medicine journal

authors： Cheung YM,O'Brien R,Ekinci EI

更新日期：2019-12-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was ...

journal_title：Internal medicine journal

authors： Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie B

更新日期：2012-01-01 00:00:00

abstract：:Decompressive hemicraniectomy (DHC) has been shown to reduce mortality in malignant middle cerebral artery (MCA) infarction. Our primary objective was to compare 1-year mortality between patients receiving DHC for malignant MCA infarction at our institution based on hospital of origin. We retrospectively reviewed the ...

journal_title：Internal medicine journal

authors： Smyth D,Weatherall M,Rosemergy I,Woon K,Lanford J

更新日期：2018-10-01 00:00:00

abstract：:The annual Leonard Ball Orations illustrate changing perspectives in Australia over 30 years on medical and social effects of misuse of alcohol and other substances. The first oration, in 1968, examined causal factors in the context of 'agent', 'purveyor' and 'host' and provided themes for subsequent orators. In regar...

journal_title：Internal medicine journal

authors： Mackay IR

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Since Hinton first published his observations on the distress of patients dying on a medical ward in 1963, there has been increasing awareness of the palliative care needs in patients who have non malignant diseases. Patients with advanced chronic obstructive pulmonary disease (COPD) are known to have compar...

journal_title：Internal medicine journal

authors： Iupati SP,Ensor BR

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The highest healthcare expenditures occur towards the end of life. Costs relate to hospital admissions and investigations to diagnose, prognosticate and direct treatment. AIMS:AnAustralian study to compare the cost of investigations in the last 72 h of life between an inpatient palliative care unit (PCU) an...

journal_title：Internal medicine journal

authors： Gogna G,Broadbent A,Baade I

更新日期：2020-05-01 00:00:00

abstract：:Over the last 20 years, clinical medicine has witnessed rapid expansion in its underlying evidence base, greater demand for accountability in clinicians' use of limited resources and increasing societal expectation for health care that confers proven benefit at reasonable cost to all eligible recipients. Health servic...

journal_title：Internal medicine journal

authors： Scott I,Campbell D

更新日期：2002-03-01 00:00:00

abstract：AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...

journal_title：Internal medicine journal

authors： Thorne K,Jayathissa S,Dee S,Briggs N,Taylor J,Reid S,De Silva K,Dean J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome occurs in one to six per 1000 pregnancies; maternal death has been reported in 1-24% of cases. Vague presentation is common; hypertension and proteinuria which characterise pre eclampsia are often absent when HELLP syndrome presents. Physi...

journal_title：Internal medicine journal

authors： Jayawardena L,Mcnamara E

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:In patients with chronic idiopathic thrombocytopenic purpura (cITP), the platelet count tends to be quite variable and, in the majority of cases, specific therapy is not warranted on a regular basis. However, patients with low platelet count (<30 nL) or with bleeding complications would require therapy, su...

journal_title：Internal medicine journal

authors： Ramakrishna R,Rehman A,Ramakrishna S,Alexander W,Yeo WW

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Off-label use of rituximab in lupus nephritis is reported to be beneficial. While the optimal dose is unknown, the regimen of four intravenous doses of 375 mg/m(2) is commonly employed, despite expense and potential side-effects. AIM:To investigate the response to single-dose rituximab, added to standard co...

journal_title：Internal medicine journal

authors： Kotagiri P,Martin A,Hughes P,Becker G,Nicholls K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF), an important and treatable cause of ischaemic stroke, can occur as a sustained or a paroxysmal arrhythmia. Continuous cardiac rhythm monitoring (Holter monitoring) is often performed in stroke patients to identify paroxysmal AF, which is an indication for warfarin anti-coagulation i...

journal_title：Internal medicine journal

authors： Shafqat S,Kelly PJ,Furie KL

更新日期：2004-06-01 00:00:00