What is new in lipid-lowering therapies in diabetes?

abstract：:We hereby present two case reports of moderate coronavirus disease patients, suffering from profound hypoxaemia, further deteriorating later on. A schedule pre-planned awake prone position manoeuvres were executed during their hospital stay. Following this, the patients' saturation improved, later to be weaned from ox...

journal_title：Internal medicine journal

authors： Cohen D,Wasserstrum Y,Segev A,Avaky C,Negru L,Turpashvili N,Anani S,Zilber E,Lasman N,Athamna A,Segal O,Shenhav-Saltzman G,Segal G

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Early involvement of palliative care and advance care planning improves quality of life outcomes and survival for patients with advanced lung cancer, however there are barriers to implementation. AIMS AND METHODS:A single-centre prospective audit reviewing "Goals of Care" (GOC) form completion and palliativ...

journal_title：Internal medicine journal

authors： Conduit C,Thompson M,Thomas R,Nott L,Wuttke M

更新日期：2020-03-23 00:00:00

abstract：:Imatinib mesylate (IM) is currently used as the first therapeutic choice against chronic myelogenous leukaemia (CML). Because IM poorly penetrates the blood-brain barrier, IM-treated CML patients may have a potential risk of central nervous system (CNS) involvement. Here we report a case with lymphoid blast crisis iso...

journal_title：Internal medicine journal

authors： Isobe Y,Sugimoto K,Masuda A,Hamano Y,Oshimi K

更新日期：2009-06-01 00:00:00

abstract：:It has been stated that academic medicine is in a worldwide crisis. Is this decline in hospital academic practice a predictable consequence of modern clinical practice with its emphasis on community and outpatient-based services as well as a corporate health-care ethos or does it relate to innate problems in the train...

journal_title：Internal medicine journal

authors： Wilson A

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The effects of empagliflozin on cardiac structure and function are not known. AIMS:To examine the changes in cardiac structure and function following the addition of empagliflozin in patients with type 2 (T2D) diabetes using cardiac magnetic resonance (CMR) imaging. METHODS:Twenty patients attending a spec...

journal_title：Internal medicine journal

authors： Cohen ND,Gutman SJ,Briganti EM,Taylor AJ

更新日期：2019-08-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...

journal_title：Internal medicine journal

authors： Thorne K,Jayathissa S,Dee S,Briggs N,Taylor J,Reid S,De Silva K,Dean J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Anticipating the prospect of specific treatment, we studied a large group of Australians with Fabry's disease. AIMS:We aimed to: (i) document the clinical features of Fabry's disease in Australian patients, (ii) test the hypothesis that clinical features vary with specific mutation and blood group and (iii)...

journal_title：Internal medicine journal

authors： Galanos J,Nicholls K,Grigg L,Kiers L,Crawford A,Becker G

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:In an era of growing subspecialisation there has been significant research into the role, determinants and outcomes of outpatient referrals but very little on inpatient specialty referrals from general medical units. AIMS:This study aims to describe and compare the rate of specialty referrals from inpatient...

journal_title：Internal medicine journal

authors： Brown MG,Campbell D,Maydom BW

更新日期：2014-09-01 00:00:00

abstract：:A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...

journal_title：Internal medicine journal

authors： Sharma R,Koller L,Barclay P,Liddle C

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Low socioeconomic status is associated with cardiovascular diseases, and an association with atrial fibrillation (AF) could guide screening. AIM:To investigate if indices of advantage/disadvantage (IAD), index of education/occupation (IEO) and index of economic resources were associated with incident AF, in...

journal_title：Internal medicine journal

authors： Ramkumar S,Ochi A,Yang H,Nerlekar N,D'Elia N,Potter EL,Murray IC,Nattraj N,Wang Y,Marwick TH

更新日期：2019-10-01 00:00:00

abstract：:This pilot study in a prospective cohort of 20 cryptogenic stroke patients showed that a significant proportion has paroxysmal atrial fibrillation undetected by 24-h Holter monitoring. However, longer monitoring with 28-day Holter was poorly tolerated and still insufficiently sensitive for paroxysmal atrial fibrillati...

journal_title：Internal medicine journal

authors： Tu HT,Spence S,Kalman JM,Davis SM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Management of adrenal incidentalomas (AI) is becoming more conservative, based on international data showing a low incidence of functional or malignant lesions. The clinical characteristics of AI in New Zealand are unknown. Therefore, whether the AI guidelines apply to the New Zealand population is also unkn...

journal_title：Internal medicine journal

authors： Goh Z,Phillips I,Hunt PJ,Soule S,Cawood TJ

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND/AIM:This study aimed to report the clinical characteristics and outcomes of Australian patients treated with eculizumab for atypical haemolytic uraemic syndrome (aHUS). METHODS:A retrospective cohort study was undertaken of all patients in Australia treated with eculizumab provided in a compassionate access...

journal_title：Internal medicine journal

authors： Mallett A,Hughes P,Szer J,Tuckfield A,Van Eps C,Cambell SB,Hawley C,Burke J,Kausman J,Hewitt I,Parnham A,Ford S,Isbel N

更新日期：2015-10-01 00:00:00

abstract：AIM:To develop a well-tolerated outpatient chemotherapy regimen for hormone-insensitive prostate cancer. METHOD:Forty patients received carboplatin 20 mg/m2 by continuous ambulatory infusion with oral etoposide 50 mg/day for 21 days repeated every 6 weeks. RESULTS:Four patients had a partial response and 16 patients ...

journal_title：Internal medicine journal

authors： Olver I,Keefe D,Myers M

更新日期：2005-07-01 00:00:00

abstract：:In this essay, I reflect on my experience as a multiple sclerosis patient in order to identify some of the unique challenges that chronic disability poses in the physician-patient relationship. I suggest that it is important to broaden the goals of the clinical encounter to incorporate personal (as opposed to simply b...

journal_title：Internal medicine journal

authors： Toombs SK

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Since 1995 patients with relapsed aggressive non-Hodgkin lymphoma have been treated with high-dose chemotherapy (HDC) instead of standard dose chemotherapy (SC) because of superior survival shown in the 'Parma study'. As HDC involves hospital admission and intensive supportive care, the cost of HDC would be ...

journal_title：Internal medicine journal

authors： Prajogo J,Neil A,Duke J,Zhang H,Stokes B,Rowlings P

更新日期：2009-08-01 00:00:00

abstract：:Parathyroid hormone (PTH) is the predominant regulator of calcium/phosphate homeostasis in the human body. Beside this classical function, preclinical and clinical studies indicated a relevant role for PTH in mobilisation of bone marrow-derived cells into peripheral blood. In addition, recombinant PTH (teriparatide) w...

journal_title：Internal medicine journal

authors： Grabmaier U,Huber BC,Franz WM,Koch E,Brunner S

更新日期：2015-08-01 00:00:00

abstract：:Paradigms for managing acromegaly have undergone major changes in the past two decades. This has been brought about by combining surgical, pharmacological and radiotherapeutic approaches that provide tight biochemical control to reduce mortality to that of the general population. The biochemical targets for treatment ...

journal_title：Internal medicine journal

authors： Burt MG,Ho KK

更新日期：2006-07-01 00:00:00

abstract：:A case of metformin encephalopathy is presented in a patient on haemodialysis for end-stage diabetic renal failure. The patient presented with frequent falls and clinical signs of Parkinsonism, on a background of recent anorexia and significant weight loss. Magnetic resonance imaging showed bilateral, symmetrical abno...

journal_title：Internal medicine journal

authors： McGarvey C,Franconi C,Prentice D,Bynevelt M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The role of brentuximab peri-allogeneic transplantation in patients with relapsed and/or refractory CD30 positive lymphomas remains poorly defined. AIM:To assess the outcome of use of brentuximab as a bridge to allogeneic stem cell transplantation (SCT) in patient with relapsed/refractory CD30+ classic Hodg...

journal_title：Internal medicine journal

authors： Mediwake H,Morris K,Curley C,Butler J,Kennedy G

更新日期：2017-05-01 00:00:00

abstract：:The adverse fallout following the Royal Australasian College of Physician's (RACP) introduction to computer-based testing that was disrupted in the February 2018 examinations, aroused great sympathy for the candidates and perhaps rekindled worrying memories by the College fellowship. The RACP's entrance procedures hav...

journal_title：Internal medicine journal

authors： H Short B

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:There is limited information on the risk of metastatic breast cancer (MBC) to inform younger women, particularly those under 40 years. AIMS:We conducted a retrospective analysis of a population-based cohort study to describe the risk, site and prognosis of MBC in young women under 40 years with an initial d...

journal_title：Internal medicine journal

authors： Tjokrowidjaja A,Lee CK,Houssami N,Lord S

更新日期：2014-08-01 00:00:00

abstract：:Prior randomised studies of immunoglobulin replacement therapy have studied mixed populations with or without a history of infections. Immunoglobulin therapy is expensive and in limited supply suggesting that optimising patient selection is of value. In this retrospective study, infection history identified high-risk ...

journal_title：Internal medicine journal

authors： Paxton L,Hawkins C,Crispin P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Effective clinical handover has always been integral to delivering safe, high-quality care in medical wards. AIM:As handover activity increases in importance we wanted to explore the experience of physicians and trainee doctors. There is little research on internal medicine handover with even less based on ...

journal_title：Internal medicine journal

authors： Donnelly S,Dinesh D,Dew K,Stubbe M

更新日期：2019-05-01 00:00:00

abstract：:Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...

journal_title：Internal medicine journal

authors： Pokorny AM,Gittins CB

更新日期：2015-10-01 00:00:00

abstract：:The prevalence of Helicobacter pylori in Western societies has rapidly declined, as reflected by the consistent decline in peptic ulcer disease. Nevertheless, there remains a cohort of the elderly population with a high prevalence of H. pylori infection. While the benefits of H. pylori eradication for H. pylori-associ...

journal_title：Internal medicine journal

authors： Duggan A

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Population-based studies of the prevalence of all functional gastrointestinal disorders (FGID) using the Rome II criteria are lacking. It is also not certain whether subjects who meet the Rome II criteria for an FGID are different in terms of demographic and psychological characteristics from those subjects ...

journal_title：Internal medicine journal

authors： Boyce PM,Talley NJ,Burke C,Koloski NA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Extreme heat is a public health priority in Australia with the health effects of cold poorly studied. A record-breaking cold winter prompted an institutional investigation into the epidemiology and outcomes of hypothermic presentations. AIMS:To describe the clinical and epidemiological characteristics of hy...

journal_title：Internal medicine journal

authors： Forcey DS,FitzGerald MP,Burggraf MK,Nagalingam V,Ananda-Rajah MR

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) is a subgroup of oncogene addicted lung cancer that predicts response to tyrosine kinase inhibitors (TKI). However, there is variability in response and survival outcomes in patients with EGFR mutation treated with TKI. AIM:T...

journal_title：Internal medicine journal

authors： Ding PN,Roberts TL,Chua W,Becker TM,Descallar J,Yip PY,Bray V

更新日期：2017-12-01 00:00:00