Dangerous liaisons: doctors-in-training and the pharmaceutical industry.

abstract：:As life expectancy for people living with human immunodeficiency virus (HIV) (PLWHIV) increases, management models for HIV infection are changing. To understand approaches to practice within this shifting climate and across different medical settings, in 2017 we conducted a baseline survey among the main medical pract...

journal_title：Internal medicine journal

authors： Smith DE,Woolley IJ,Russell DB,Bisshop F,Furner V

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:In 2004, the Pharmaceutical Benefits Scheme (PBS) listed infliximab as a subsidised treatment for ankylosing spondylitis (AS). Eligibility to receive this treatment for AS involved fulfilling several criteria. AIM:To examine the medical literature concerning response to tumor necrosis factor (TNF)-alpha inh...

journal_title：Internal medicine journal

authors： Smith MD,Ahern MJ

更新日期：2006-02-01 00:00:00

abstract：:The mortality rate post admission to hospital after successful resuscitation from out-of-hospital cardiac arrest is high, with significant variation between regions and individual institutions. While prehospital factors such as age, bystander cardiopulmonary resuscitation and total cardiac arrest time are known to inf...

journal_title：Internal medicine journal

authors： Stub D,Bernard S,Smith K,Bray JE,Cameron P,Duffy SJ,Kaye DM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Delirium is common in hospitalised patients but its epidemiology remains poorly characterised. AIMS:To test the hypothesis that patient demographics, clinical phenotype, management and outcomes of patient with delirium in hospital ward patients differ from intensive care unit (ICU) patients. METHODS:Retros...

journal_title：Internal medicine journal

authors： Canet E,Amjad S,Robbins R,Lewis J,Matalanis M,Jones D,Bellomo R

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The association between the use of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) and mortality in end-stage renal disease (ESRD) patients lacks sufficient evidence. AIM:To investigate the efficacy of ACEI and ARB in ESRD patients. METHODS:This nationwide retrospect...

journal_title：Internal medicine journal

authors： Lee HF,See LC,Chan YH,Yeh YH,Wu LS,Liu JR,Tu HT,Wang CL,Kuo CT,Chang SH

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Polyserositis (PS) is the inflammation, with effusion, of different serous membranes. It has been associated with different aetiologies, but the aetiology of PS remains unknown in a high percentage of patients. AIMS:The general objective of this retrospective study was to analyse the aetiology of PS cases s...

journal_title：Internal medicine journal

authors： Losada I,González-Moreno J,Roda N,Ventayol L,Borjas Y,Domínguez FJ,Fernández-Baca V,García-Gasalla M,Payeras A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is a common cause of incidental liver test abnormalities. General practitioners (GP) have a key role in identifying people with NAFLD at risk of significant liver disease. Recent specialist guidelines emphasise the use of fibrosis algorithms or serum biomarkers rathe...

journal_title：Internal medicine journal

authors： Patel PJ,Banh X,Horsfall LU,Hayward KL,Hossain F,Johnson T,Stuart KA,Brown NN,Saad N,Clouston A,Irvine KM,Russell AW,Valery PC,Williams S,Powell EE

更新日期：2018-02-01 00:00:00

abstract：AIM:To evaluate New Zealand media articles on their coverage of key issues regarding health interventions and whether it is consistent with available evidence. METHODS:A retrospective analysis was carried out of all articles published in five New Zealand media sources over a 6-week period between 15 October and 26 Nov...

journal_title：Internal medicine journal

authors： Robinson C,Cutfield N,Mottershead J,Sharples K,Richards R,Kingan J,Ledgard C,Liyanage A,McLean J,Nahab F,Stewart F,Strachan S,Tucker K,Zhang Z

更新日期：2018-08-01 00:00:00

abstract：:Mechanical ventilation as a resource is limited and may lead to poor outcomes in at-risk populations. Critical care supports may not be preferred by those at risk of deterioration in the COVID-19 setting. Patient-centred communication and shared decision-making should continue to remain central to clinical practice. ...

journal_title：Internal medicine journal

authors： Simpson N,Milnes S,Steinfort D

更新日期：2020-06-01 00:00:00

abstract：:The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...

journal_title：Internal medicine journal

authors： Bray JE,Coughlan K,Bladin C

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The effects of empagliflozin on cardiac structure and function are not known. AIMS:To examine the changes in cardiac structure and function following the addition of empagliflozin in patients with type 2 (T2D) diabetes using cardiac magnetic resonance (CMR) imaging. METHODS:Twenty patients attending a spec...

journal_title：Internal medicine journal

authors： Cohen ND,Gutman SJ,Briganti EM,Taylor AJ

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Pulmonary embolism (PE) is associated with significant morbidity and mortality. PE is a heterogeneous entity that causes a wide variety of clinical presentations, making it imperative to establish which clinical symptoms, signs and biomarkers can influence the pretest probability of PE to aid clinicians and ...

journal_title：Internal medicine journal

authors： Sethwala A,Wang X,Sturm EE,Collins KL,O'Donnabhain R,Friedman ND

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Bali, Indonesia, presents significant infectious and non-infectious health risks for Australian travellers. Understanding this spectrum of illnesses has the potential to assist clinicians in evaluating unwell returning travellers and guide provision of pre-travel advice. AIM:To describe the spectrum of illn...

journal_title：Internal medicine journal

authors： Sohail A,McGuinness SL,Lightowler R,Leder K,Jomon B,Bain CA,Peleg AY

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:There is a high risk of developing venous thromboembolism (VTE) following total knee arthroplasty (TKA). Conventional thromboprophylactic agents have limitations, such as route of administration, the need for monitoring, narrow therapeutic windows and interactions. Apixaban is a new oral anticoagulant with t...

journal_title：Internal medicine journal

authors： King DA,Pow RE,Dickison DM,Vale PR

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limits quality of life. The CHA2 DS2 VASc score (congestive heart failure/left ventricular dysfunction, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular d...

journal_title：Internal medicine journal

authors： Mlodawska E,Tomaszuk-Kazberuk A,Lopatowska P,Kaminski M,Musial WJ

更新日期：2017-03-01 00:00:00

abstract：:The phenomenon of addiction is complex, although its expression clinically is relatively straightforward. There is a series of neurophysiological changes that mediate changes in the mesolimbic and mesocortical systems which in turn lead to disturbances in reward mechanisms. These then act to perpetuate the cycle of in...

journal_title：Internal medicine journal

authors： Foy A

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Neutropenic fever is a medical emergency, which poses a significant morbidity and mortality risk to cancer patients receiving chemotherapy. National guidelines recommend that patients presenting with suspected neutropenic fever receive appropriate intravenous antibiotics within 60 min of admission. AIM:We a...

journal_title：Internal medicine journal

authors： Skiba R,Sikotra N,Ball T,Arellano A,Gabbay E,Clay TD

更新日期：2020-08-01 00:00:00

abstract：:It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...

journal_title：Internal medicine journal

authors： Tang ML,Mullins RJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is a newly recognised condition that is apparently increasing in prevalence, and the aetiology is poorly understood. The role of aeroallergens in EoE is controversial, given the success of dietary therapy. Massive aeroallergen exposure leading to food bolus obstruction events (...

journal_title：Internal medicine journal

authors： Philpott HL,Nandurkar S,Thien F,Bloom S,Lin E,Goldberg R,Boyapati R,Finch A,Royce SG,Gibson PR

更新日期：2015-09-01 00:00:00

abstract：:In Australia, mutations in epidermal growth factor mutations (EGFR) occur in 15% of patients diagnosed with non-small-cell lung cancer and are found with higher frequency in female, non-smokers of Asian ethnicity. Activating mutations in the EGFR gene are rarely described in SCLC. We present two cases of de novo EGFR ...

journal_title：Internal medicine journal

authors： Thai A,Chia PL,Russell PA,Do H,Dobrovic A,Mitchell P,John T

更新日期：2017-09-01 00:00:00

abstract：:Despite the increasing use and costs associated with external management consultancy for healthcare improvement, there is a paucity of formal evaluations examining impact. This paper aims to: (i) discuss the potential benefits and disadvantages of external consultancies in addressing complex healthcare challenges and ...

journal_title：Internal medicine journal

authors： Skouteris H,Kirkpatrick I,Currie G,Braithwaite J,Teede H

更新日期：2019-11-01 00:00:00

abstract：:Individualised drug dosing has been shown to improve patient outcomes and reduce adverse drug events. One method of individualised medicine is the Bayesian approach, which uses prior information about how the population responds to therapy, to inform clinicians about how a specific individual is responding to their cu...

journal_title：Internal medicine journal

authors： Donagher J,Martin JH,Barras MA

更新日期：2017-05-01 00:00:00

abstract：:This paper examines the differences between clinical and public health ethics and provides several examples of contemporary public health challenges that pose ethical questions. The relations among ethics, rights and obligations are explored, because public health philosophers propose these as different ways for publi...

journal_title：Internal medicine journal

authors： Leeder SR

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND/AIM:Although induction chemotherapy comprising high-dose cytarabine (HiDAC) in combination with idarubicin and etoposide or 'ICE' for adult acute myeloid leukaemia (AML) produces a complete remission rate of nearly 80%, gastrointestinal toxicity is significant. Omission of etoposide may produce similar clini...

journal_title：Internal medicine journal

authors： Low M,Lee D,Coutsouvelis J,Patil S,Opat S,Walker P,Schwarer A,Salem H,Avery S,Spencer A,Wei A

更新日期：2013-03-01 00:00:00

abstract：:Diabetes can lead to a myriad of microvascular and macrovascular complications - with the leading cause of mortality in diabetes being cardiovascular disease. Low-density lipoprotein cholesterol, along with non-high-density lipoprotein cholesterol and triglycerides are proven, modifiable risk factors for cardiovascula...

journal_title：Internal medicine journal

authors： Cheung YM,O'Brien R,Ekinci EI

更新日期：2019-12-01 00:00:00

abstract：:Waldenström macroglobulinaemia (WM) is an indolent B-cell malignancy characterised by the presence of immunoglobulin M (IgM) paraprotein and bone marrow infiltration by clonal small B lymphocytes, plasmacytoid lymphocytes and plasma cells. The symptoms of WM are protean, often follow an asymptomatic phase and may incl...

journal_title：Internal medicine journal

authors： Talaulikar D,Tam CS,Joshua D,Ho JP,Szer J,Quach H,Spencer A,Harrison S,Mollee P,Roberts AW,Horvath N,Lee C,Zannettino A,Brown R,Augustson B,Jaksic W,Gibson J,Kalff A,Johnston A,Trotman J,Kalro A,Grigoriadis G,

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukaemia (CLL) frequently responds to chemoimmunotherapy combining cytotoxic chemotherapy and monoclonal antibodies. However, CLL is associated with significant genetic heterogeneity, and some high-risk forms are known to be chemo-resistant and associated with early relapse. AIMS:To rev...

journal_title：Internal medicine journal

authors： Kuss BJ,Tam CS

更新日期：2017-12-01 00:00:00

abstract：:This article reports the findings of a survey developed to assess the current use of antifungal prophylaxis among haematology and infectious disease clinicians across Australia and New Zealand, and their alignment with existing consensus guidelines for the use of antifungal agents in the haematology/oncology setting (...

journal_title：Internal medicine journal

authors： van Hal SJ,Gilroy NM,Morrissey CO,Worth LJ,Szer J,Tam CS,Chen SC,Thursky KA,Slavin MA

更新日期：2014-12-01 00:00:00

abstract：:The incidence of tuberculosis in the non-indigenous Australian population is low. However, in this paper we report on three cases of cavitating disease, which seem to be associated with a common illicit drug habit namely smoking marijuana using a makeshift pipe or bong. There was a total of 34 positive contacts of the...

journal_title：Internal medicine journal

authors： Thu K,Hayes M,Miles S,Tierney L,Foy A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:High inflammatory bowel disease (IBD) rates have been reported in Australasia, but no state-wide studies have yet been performed. AIM:This study estimates the 1-year incidence and point prevalence of IBD in the state of Tasmania, Australia. It also reports clinical outcomes after 12 months of diagnosis in a...

journal_title：Internal medicine journal

authors： Bhatia R,Yeoh SW,Vaz K,Studd C,Wilson J,Bell S,Otahal P,Venn A

更新日期：2019-05-01 00:00:00