Individualised medicine: why we need Bayesian dosing.

abstract：BACKGROUND:The aim of this study was to describe the activity of a lung cancer multidisciplinary clinic (MDC) and examine whether this model of clinical practice results in adherence to best-practice guidelines. METHODS:Prospective analysis of demographic and clinical data in 431 patients referred to a lung cancer MDC...

journal_title：Internal medicine journal

authors： Conron M,Phuah S,Steinfort D,Dabscheck E,Wright G,Hart D

更新日期：2007-01-01 00:00:00

abstract：:Ambulatory care is an important service for patients with the COVID-19 infection especially in a regional area where most of the patients underwent home isolation. Escalation of treatment and timely transition to inpatient care are critical when COVID-19 patients deteriorate. Equally important is ensuring transfer int...

journal_title：Internal medicine journal

authors： Lwin N,Burgess J,Johnston C,Johnson N,Chung S

更新日期：2020-10-01 00:00:00

abstract：:In this essay, I reflect on my experience as a multiple sclerosis patient in order to identify some of the unique challenges that chronic disability poses in the physician-patient relationship. I suggest that it is important to broaden the goals of the clinical encounter to incorporate personal (as opposed to simply b...

journal_title：Internal medicine journal

authors： Toombs SK

更新日期：2004-11-01 00:00:00

abstract：:Almost everywhere in the body there are phospholipids, not only comprising the lipid bilayer of membranes, but also in the free state. What is seldom appreciated, except in respirology, is that these 'free' phospholipids are unusual in that many are highly surface active. Surface activity is a property of certain subs...

journal_title：Internal medicine journal

authors： Hills BA

更新日期：2002-04-01 00:00:00

abstract：:There is accumulating evidence that point-of-care delivery of clinical information such as evidence-based medicine, practice guidelines and drug information can streamline clinical practice and reduce preventable errors. In Australia, hospital-based physicians have -generally been slow to fully use these resources to ...

journal_title：Internal medicine journal

authors： Wilcox RA,Whitham EM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Acute coronary syndromes (ACS) management is now well informed by guidelines extrapolated from clinical trials. However, most of these data have been acquired outside the local context. We sought to describe the current patterns of ACS care in Australia. METHODS:The Acute Coronary Syndrome Prospective Audit...

journal_title：Internal medicine journal

authors： Chew DP,Amerena J,Coverdale S,Rankin J,Astley C,Brieger D

更新日期：2007-11-01 00:00:00

abstract：:The adverse fallout following the Royal Australasian College of Physician's (RACP) introduction to computer-based testing that was disrupted in the February 2018 examinations, aroused great sympathy for the candidates and perhaps rekindled worrying memories by the College fellowship. The RACP's entrance procedures hav...

journal_title：Internal medicine journal

authors： H Short B

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Bronchodilator reversibility (BDR) and inhaled corticosteroid (ICS) use were assessed for volunteers who responded to an advertisement requesting current or ex-smokers who were experiencing breathlessness to attend for lung function testing. METHODS:One hundred and fifty-four volunteers responded. ...

journal_title：Internal medicine journal

authors： Reid DW,Soltani A,Johns DP,Bish R,Williams TJ,Burns GP,Walters EH

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Medical school and resident training programmes offer different learning opportunities and outcomes. The aim of the study was to assess medical student and intern experience in common clinical procedures. METHODS:Interns employed in a metropolitan teaching hospital from 2000 to 2004 completed a survey of ex...

journal_title：Internal medicine journal

authors： Boots RJ,Egerton W,McKeering H,Winter H

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:As direct-to-consumer personal genome testing (DTC-PGT) is increasingly available in Australia, knowledge of Australians' perceptions and attitudes towards this technology is needed in order to assess the (potential) impact it might have on the Australian public and healthcare system. AIMS:To explore the kn...

journal_title：Internal medicine journal

authors： Savard J,Mooney-Somers J,Newson AJ,Kerridge I

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The elderly obese are at increased risk of mortality and morbidity of many obesity-related chronic diseases, such as hypertension, diabetes and coronary heart disease. This study was designed to investigate the epidemiological features of overweight and obesity in older rural Chinese. METHODS:A cross-sectio...

journal_title：Internal medicine journal

authors： Zhang X,Sun Z,Zhang X,Zheng L,Liu S,Xu C,Li J,Zhao F,Li J,Hu D,Sun Y

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Surveillance for colorectal neoplasia in inflammatory bowel disease (IBD) is widely practised despite a lack of convincing mortality reduction. The psychological impact of this approach is largely unexplored. AIM:To examine psychological well-being among IBD subjects undergoing colonoscopic surveillance for...

journal_title：Internal medicine journal

authors： Mountifield R,Bampton P,Prosser R,Mikocka-Walus A,Andrews JM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Tuberculous lymphadenitis is the commonest form of extrapulmonary tuberculosis. However, the optimal approach to diagnosis, employing biopsy by either fine needle aspiration (FNA) or surgical excision, remains uncertain. AIMS:To evaluate the diagnostic value of biopsy using each of the component diagnostic ...

journal_title：Internal medicine journal

authors： Knox J,Lane G,Wong JS,Trevan PG,Karunajeewa H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Guidelines recommend screening for strongyloidiasis prior to immunosuppression in those at epidemiological risk, as hyperinfection following immunosuppression is often fatal. The uptake of this recommendation is unknown, and we aimed to explore this in our setting. AIMS:Determine the proportion of adult pat...

journal_title：Internal medicine journal

authors： Muhi S,Ko DK,McGuinness SL,Biggs BA,Mahanty S,Delany C

更新日期：2020-07-20 00:00:00

abstract：:Sleep disturbance during menopause is a common and important complaint faced by many women. There are many factors that may play a role in this problem, including vasomotor symptoms and changing hormone levels, circadian rhythm abnormalities, exacerbation of primary insomnia, mood disorders, coexistent medical conditi...

journal_title：Internal medicine journal

authors： Ameratunga D,Goldin J,Hickey M

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:In an era of growing subspecialisation there has been significant research into the role, determinants and outcomes of outpatient referrals but very little on inpatient specialty referrals from general medical units. AIMS:This study aims to describe and compare the rate of specialty referrals from inpatient...

journal_title：Internal medicine journal

authors： Brown MG,Campbell D,Maydom BW

更新日期：2014-09-01 00:00:00

abstract：:To improve organ donation processes and outcomes, many Australian hospitals have introduced donation after cardiac death (DCD) following the 2010 publication of the National Protocol for DCD. As emergency clinicians play a significant role in identifying potential DCD donors, it is critical to assess their support and...

journal_title：Internal medicine journal

authors： Marck CH,Neate SL,Weiland TJ,Hickey BB,Jelinek GA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The effects of empagliflozin on cardiac structure and function are not known. AIMS:To examine the changes in cardiac structure and function following the addition of empagliflozin in patients with type 2 (T2D) diabetes using cardiac magnetic resonance (CMR) imaging. METHODS:Twenty patients attending a spec...

journal_title：Internal medicine journal

authors： Cohen ND,Gutman SJ,Briganti EM,Taylor AJ

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Infections and antibiotic resistance patterns in patients attending regional Australian cancer centres are poorly described. AIMS:To document patient characteristics, infection types, patterns of antibiotic resistance and outcomes in all patients with cancer requiring inpatient management for suspected infe...

journal_title：Internal medicine journal

authors： De Silva N,Jackson J,Steer C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Many patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have type 2 respiratory failure (T2RF). Often arterial blood gases are not performed and correlation with venous blood gases (VBG) is controversial. The venous pH and bicarbonate (HCO3 ) are useful, but VBG pCO2 (PvCO2 )...

journal_title：Internal medicine journal

authors： Wong EKC,Lee PCS,Ansary S,Asha S,Wong KKH,Yee BJ,Ng AT

更新日期：2019-07-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：:Neuroimaging in dementia has focused on documenting any burden of vascular disease or excluding any reversible intracranial pathology. We review the use of computed tomography to examine for medial temporal lobe atrophy in dementia and compare this with a case series of such measurements from our memory clinic. Measur...

journal_title：Internal medicine journal

authors： Rose M,Scharf S

更新日期：2008-02-01 00:00:00

abstract：:Systemic AL amyloidosis is a plasma cell dyscrasia with a characteristic clinical phenotype caused by multi-organ deposition of an amyloidogenic monoclonal protein. This condition poses a unique management challenge due to the complexity of the clinical presentation and the narrow therapeutic window of available thera...

journal_title：Internal medicine journal

authors： Weber N,Mollee P,Augustson B,Brown R,Catley L,Gibson J,Harrison S,Ho PJ,Horvath N,Jaksic W,Joshua D,Quach H,Roberts AW,Spencer A,Szer J,Talaulikar D,To B,Zannettino A,Prince HM

更新日期：2015-04-01 00:00:00

abstract：:More than 177 000 potentially preventable healthcare-associated infections (HAIs) occur per annum in Australia with sizable attributable mortality. Organizational systems to protect against HAI in hospitals in Australia are relatively poorly developed. Awareness and practice of infection control by medical and other h...

journal_title：Internal medicine journal

authors： Ferguson JK

更新日期：2009-09-01 00:00:00

abstract：:Here we report the case of a 69-year-old Chinese Han woman who presented with liver cirrhosis, diabetes mellitus, skin hyperpigmentation, hyperferritinaemia and high transferrin saturation. Subsequent genetic analyses identified a novel heterozygous mutation (p.Cys326Phe) in the SLC40A1 gene. This is the first report ...

journal_title：Internal medicine journal

authors： Chen SR,Yang LQ,Chong YT,Jie YS,Wu YK,Yang J,Lin GL,Li XH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The consumption of Energy Drinks (Edks), has increased significantly in the last years, with a growing market that is estimated to reach $61 billion by 2021 worldwide. Several studies demonstrated the physiological and pathological effects of these substances contained in Edks. The most common ingredient con...

journal_title：Internal medicine journal

authors： Piccioni A,Covino M,Zanza C,Longhitano Y,Tullo G,Bonadia N,Rinninella E,Ojetti V,Gasbarrini A,Franceschi F

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Stroke neurologists, vascular surgeons, interventional neuroradiologists and interventional cardiologists have embraced carotid angioplasty and stenting (CAS) because of potential advantages over carotid endarterectomy (CEA). At Austin Health, a multidisciplinary neuro-interventional group was formed to stan...

journal_title：Internal medicine journal

authors： Mak CS,Chambers BR,Clark DJ,Molan M,Brooks M,Roberts N,Fell G,Roberts AK,New G,Donnan GA

更新日期：2011-11-01 00:00:00

abstract：:The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by...

journal_title：Internal medicine journal

authors： Lin MS,Dai YS,Pwu RF,Chen YH,Chang NC

更新日期：2005-03-01 00:00:00

abstract：:The phenomenon of addiction is complex, although its expression clinically is relatively straightforward. There is a series of neurophysiological changes that mediate changes in the mesolimbic and mesocortical systems which in turn lead to disturbances in reward mechanisms. These then act to perpetuate the cycle of in...

journal_title：Internal medicine journal

authors： Foy A

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiac myxoma is a rare but important cause of stroke, which affects young people. More recently the diagnosis has been enhanced by the use of echocardiograms. We aimed to review the neurological presentations, including stroke, of cardiac myxoma in this modern era of diagnosis and management. MET...

journal_title：Internal medicine journal

authors： Ekinci EI,Donnan GA

更新日期：2004-05-01 00:00:00