Mobilisation of haemopoietic stem cells in teriparatide-treated patients.

abstract：BACKGROUND:While medications may prolong life and prevent morbidity in older people, adverse effects of polypharmacy are increasingly recognised. As patients age and become frail, prescribing may be expected to focus more on symptom control and minimise potentially harmful preventive medication use that confer little b...

journal_title：Internal medicine journal

authors： Ilango S,Pillans P,Peel NM,Scott I,Gray LC,Hubbard RE

更新日期：2017-09-01 00:00:00

abstract：:Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...

journal_title：Internal medicine journal

authors： Kaazan P,Tan Z,Bednarz J,Hughes J,Grafton R,Andrews JM

更新日期：2020-09-01 00:00:00

abstract：AIM:To develop a well-tolerated outpatient chemotherapy regimen for hormone-insensitive prostate cancer. METHOD:Forty patients received carboplatin 20 mg/m2 by continuous ambulatory infusion with oral etoposide 50 mg/day for 21 days repeated every 6 weeks. RESULTS:Four patients had a partial response and 16 patients ...

journal_title：Internal medicine journal

authors： Olver I,Keefe D,Myers M

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Pleural procedures may cause serious complications when incorrectly carried out. There is a need to find effective methods for teaching how to insert a chest drain safely. AIM:To assess the effectiveness of a programme for teaching chest tube insertion using a simulation model (SuperAnnie). METHODS:Groups ...

journal_title：Internal medicine journal

authors： Hutton IA,Kenealy H,Wong C

更新日期：2008-12-01 00:00:00

abstract：:Vancomycin remains a clinically useful antibiotic despite the advent of several alternative drugs. Optimising vancomycin therapy with therapeutic drug monitoring is widely recommended. The aim of therapeutic drug monitoring is to help the clinician to achieve target pharmacodynamic parameters in the case of vancomycin...

journal_title：Internal medicine journal

authors： Avent ML,Vaska VL,Rogers BA,Cheng AC,van Hal SJ,Holmes NE,Howden BP,Paterson DL

更新日期：2013-02-01 00:00:00

abstract：:Haemophagocytic lymphohistiocytosis (HLH) is rare disorder characterised by immune activation leading to cytokine storm and end-organ failure. It is associated with poor prognosis. HLH is predominantly a disease of early childhood, where it often results from genetic defects that impair cytotoxic function of natural k...

journal_title：Internal medicine journal

authors： Lee WI,Talaulikar D,Cook MC

更新日期：2020-05-10 00:00:00

abstract：:Clarithromycin is the most documented cytochrome P450 3A4 (CYP3A4) inhibitor to cause an adverse interaction with simvastatin. This particular case is of interest as rhabdomyolysis only occurred after an increase in the dose of clarithromycin. The patient developed raised cardiac biomarkers without any obvious cardiac...

journal_title：Internal medicine journal

authors： Page SR,Yee KC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is a common cause of incidental liver test abnormalities. General practitioners (GP) have a key role in identifying people with NAFLD at risk of significant liver disease. Recent specialist guidelines emphasise the use of fibrosis algorithms or serum biomarkers rathe...

journal_title：Internal medicine journal

authors： Patel PJ,Banh X,Horsfall LU,Hayward KL,Hossain F,Johnson T,Stuart KA,Brown NN,Saad N,Clouston A,Irvine KM,Russell AW,Valery PC,Williams S,Powell EE

更新日期：2018-02-01 00:00:00

abstract：:Despite the increasing use and costs associated with external management consultancy for healthcare improvement, there is a paucity of formal evaluations examining impact. This paper aims to: (i) discuss the potential benefits and disadvantages of external consultancies in addressing complex healthcare challenges and ...

journal_title：Internal medicine journal

authors： Skouteris H,Kirkpatrick I,Currie G,Braithwaite J,Teede H

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Several epidemiological studies have suggested a positive association of coronary heart disease with both Helicobacter pylori and Chlamydia pneumoniae infection. The issue has been difficult to resolve because of the potential impact of several confounding factors, in particular, socioeconomic status for H. ...

journal_title：Internal medicine journal

authors： Fraser AG,Scragg RK,Cox B,Jackson RT

更新日期：2003-07-01 00:00:00

abstract：AIMS:To survey the practice among gastroenterologists in Australia relating to screening for latent infections and vaccination of patients with inflammatory bowel disease prior to treatment with tumour necrosis factor alpha (TNF-α) inhibitors. METHODS:A structured 15 question electronic survey was advertised to gastro...

journal_title：Internal medicine journal

authors： Gupta A,Macrae FA,Gibson PR

更新日期：2011-06-01 00:00:00

abstract：:The insulin tolerance test is considered the gold standard for assessing the hypothalamic-pituitary-adrenal and growth hormone (GH) axes, but its use varies considerably among different endocrine units. We recommend using the insulin tolerance test to assess the hypothalamic-pituitary-adrenal axis within 3 months of p...

journal_title：Internal medicine journal

authors： Sarlos S,Inder WJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Where proven cancer therapies remain unfunded, patients are faced with difficult decisions regarding personally covering some or all of the treatment cost. Clinical trials provide an alternative form of access to unfunded drugs. AIMS:To examine the patient population and utilisation of the colorectal cancer...

journal_title：Internal medicine journal

authors： Tie J,Gibbs P

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:In patients with chronic idiopathic thrombocytopenic purpura (cITP), the platelet count tends to be quite variable and, in the majority of cases, specific therapy is not warranted on a regular basis. However, patients with low platelet count (<30 nL) or with bleeding complications would require therapy, su...

journal_title：Internal medicine journal

authors： Ramakrishna R,Rehman A,Ramakrishna S,Alexander W,Yeo WW

更新日期：2015-07-01 00:00:00

abstract：:Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...

journal_title：Internal medicine journal

authors： Chen BS,Wong SHC,Hawkins S,Huggins L

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Increasing numbers of patients receiving new oral anticoagulants (NOAC) are undergoing elective surgery. The extent to which perioperative interruption of NOAC therapy and use of bridging heparin are concordant with best evidence is uncertain. AIMS:To determine: (i) concordance of NOAC and bridging heparin ...

journal_title：Internal medicine journal

authors： Wamala H,Scott IA,Caney X

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limits quality of life. The CHA2 DS2 VASc score (congestive heart failure/left ventricular dysfunction, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular d...

journal_title：Internal medicine journal

authors： Mlodawska E,Tomaszuk-Kazberuk A,Lopatowska P,Kaminski M,Musial WJ

更新日期：2017-03-01 00:00:00

abstract：:The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...

journal_title：Internal medicine journal

authors： Bray JE,Coughlan K,Bladin C

更新日期：2006-08-01 00:00:00

abstract：:A 75-year-old man of Fijian-Indian extraction complained of a 3-year history of progressive right knee pain and stiffness which were limiting his mobility. On examination, multiple hard nodules were palpable in the popliteal fossa and along the path of the quadriceps tendon. The joint line was not tender, knee flexion...

journal_title：Internal medicine journal

authors： Langguth DM,Klestov A,Denaro C

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Poor quality prescribing has been identified as one of the leading causes of medication error and adverse drug events. The aim of this study was to improve the quality of written prescriptions in a general hospital by a combination of serial audits and interventions designed to address identified deficiencie...

journal_title：Internal medicine journal

authors： Gommans J,McIntosh P,Bee S,Allan W

更新日期：2008-04-01 00:00:00

abstract：:Bronchiectasis is generally classified into cystic fibrosis and non-cystic fibrosis bronchiectasis. This review article describes non-cystic fibrosis bronchiectasis in adults. Bronchiectasis can be considered a heterogeneous condition characterized by irreversible airway dilatation with chronic bronchial infection/inf...

journal_title：Internal medicine journal

authors： King P,Holdsworth S,Freezer N,Holmes P

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Neutropenic fever is a frequently encountered complication when caring for cancer patients and can lead to intensive care admission, with high mortality rates in those patients who require invasive mechanical ventilation (IMV). Although hospital survival in this population has improved, long-term outcomes of...

journal_title：Internal medicine journal

authors： Mackintosh D,Way M,Reade MC,Dhanani J

更新日期：2020-05-01 00:00:00

abstract：:The prevalence of Helicobacter pylori in Western societies has rapidly declined, as reflected by the consistent decline in peptic ulcer disease. Nevertheless, there remains a cohort of the elderly population with a high prevalence of H. pylori infection. While the benefits of H. pylori eradication for H. pylori-associ...

journal_title：Internal medicine journal

authors： Duggan A

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Neutropenic fever is a medical emergency, which poses a significant morbidity and mortality risk to cancer patients receiving chemotherapy. National guidelines recommend that patients presenting with suspected neutropenic fever receive appropriate intravenous antibiotics within 60 min of admission. AIM:We a...

journal_title：Internal medicine journal

authors： Skiba R,Sikotra N,Ball T,Arellano A,Gabbay E,Clay TD

更新日期：2020-08-01 00:00:00

abstract：AIM:To determine diagnostic rate, complications and patient tolerability of endobronchial ultrasound-guide sheath (EBUS-GS) and computed tomography (CT)-guided percutaneous core biopsy for peripheral lung lesions. METHODS:Lesions >1 cm diameter on CT were randomised to either EBUS-GS or CT-guided biopsy. Excluded were...

journal_title：Internal medicine journal

authors： Fielding DI,Chia C,Nguyen P,Bashirzadeh F,Hundloe J,Brown IG,Steinke K

更新日期：2012-08-01 00:00:00

abstract：:The vulnerability of older people to serious underlying medical illness and adverse effects of psychotropics means that the safe and effective treatment of severe agitation can be lifesaving, the primary management goals being to create a safe environment for the patient and others, and to facilitate assessment and tr...

journal_title：Internal medicine journal

authors： Peisah C,Chan DK,McKay R,Kurrle SE,Reutens SG

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Extreme heat is a public health priority in Australia with the health effects of cold poorly studied. A record-breaking cold winter prompted an institutional investigation into the epidemiology and outcomes of hypothermic presentations. AIMS:To describe the clinical and epidemiological characteristics of hy...

journal_title：Internal medicine journal

authors： Forcey DS,FitzGerald MP,Burggraf MK,Nagalingam V,Ananda-Rajah MR

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The rate of hospital admissions for cirrhosis increased 1.3-fold during 2008-2016 in Queensland. Alcohol misuse was a contributing factor for cirrhosis in 55% of admissions and 40% of patients had at least one comorbidity. AIM:This paper examines the temporal change in aetiology of liver disease and presenc...

journal_title：Internal medicine journal

authors： Valery PC,McPhail S,Stuart KA,Hartel G,Clark PJ,O'Beirne J,Skoien R,Rahman T,Moser C,Powell EE

更新日期：2020-02-25 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a prevalent, chronic and heterogeneous endocrine condition, with reproductive, metabolic and psychological features. Insulin resistance and hyperandrogenaemia are the key pathophysiological hormonal abnormalities. Insulin resistance is a significant contributor to the reproductive a...

journal_title：Internal medicine journal

authors： Shorakae S,Boyle J,Teede H

更新日期：2014-08-01 00:00:00

abstract：:The incidence and prevalence of autoimmune diseases such as rheumatoid arthritis, primary Sjögren syndrome, scleroderma and systemic lupus erythematosus (SLE) varies with geography and ethnicity. For example, SLE is reported to be more common in populations such as African-Caribbeans and Indigenous Australians (IA). A...

journal_title：Internal medicine journal

authors： Vincent FB,Bourke P,Morand EF,Mackay F,Bossingham D

更新日期：2013-03-01 00:00:00