Phase II study of prolonged ambulatory infusion carboplatin and oral etoposide for patients progressing through hormonal therapy for prostate cancer.

abstract：BACKGROUND:The association between weather and severe acute respiratory syndrome (SARS) transmission in Beijing and Hong Kong in the 2003 epidemic was studied to examine the effect of weather on SARS transmission. METHODS:Pearson's correlation analyses and negative binomial regression analyses were used to quantify th...

journal_title：Internal medicine journal

authors： Bi P,Wang J,Hiller JE

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Bronchial thermoplasty (BT) is an approved bronchoscopic intervention for the treatment of severe asthma. However, limited published experience exists outside of clinical trials regarding patient selection and outcomes achieved. AIMS:To evaluate the effectiveness and safety of BT in patients with severe ast...

journal_title：Internal medicine journal

authors： Langton D,Sha J,Ing A,Fielding D,Wood E

更新日期：2017-05-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...

journal_title：Internal medicine journal

authors： Finlayson J,Grey D,Kavanagh L,Witt C

更新日期：2011-08-01 00:00:00

abstract：:During a pandemic when hospitals are stretched and patients need isolation, the role of hospital-in-the-home (HITH) providing acute medical care at home has never been more relevant. We aimed to define and address the challenges to acute home care services posed by the COVID-19 pandemic. Planning for service operation...

journal_title：Internal medicine journal

authors： Bryant PA,Rogers BA,Cowan R,Bowen AC,Pollard J,Hospital-in-the-Home Society Australasia.

更新日期：2020-10-01 00:00:00

abstract：:Chronic lead exposure is recognized as a potential cause of hyperuricaemia, kidney damage and hypertension. The fascinating story of lead poisoning and nephrotoxicity illustrates the utility of descriptive studies in the early elucidation of a new disease entity. The pursuit towards understanding lead nephropathy is p...

journal_title：Internal medicine journal

authors： Chow KM,Liu ZC,Szeto CC

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Surveillance for colorectal neoplasia in inflammatory bowel disease (IBD) is widely practised despite a lack of convincing mortality reduction. The psychological impact of this approach is largely unexplored. AIM:To examine psychological well-being among IBD subjects undergoing colonoscopic surveillance for...

journal_title：Internal medicine journal

authors： Mountifield R,Bampton P,Prosser R,Mikocka-Walus A,Andrews JM

更新日期：2014-02-01 00:00:00

abstract：:Despite the increasing use and costs associated with external management consultancy for healthcare improvement, there is a paucity of formal evaluations examining impact. This paper aims to: (i) discuss the potential benefits and disadvantages of external consultancies in addressing complex healthcare challenges and ...

journal_title：Internal medicine journal

authors： Skouteris H,Kirkpatrick I,Currie G,Braithwaite J,Teede H

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Many studies support the role of bilirubin as a cytoprotector in chronic inflammatory diseases, such as stroke and atherosclerosis. AIM:To investigate the relationship between serum total bilirubin levels and functional dependence in older adults. METHODS:Data from the National Health and Nutrition Examina...

journal_title：Internal medicine journal

authors： Kao TW,Chou CH,Wang CC,Chou CC,Hu J,Chen WL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：:The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...

journal_title：Internal medicine journal

authors： Bray JE,Coughlan K,Bladin C

更新日期：2006-08-01 00:00:00

abstract：:For decades, residents believed to work harder have been referred to as having a 'black cloud'. Residency training programmes recently instituted changes to improve physician wellness and achieve comparable clinical workload. All Internal Medicine residents in the internship class of 2014 at Columbia were surveyed to ...

journal_title：Internal medicine journal

authors： Schissler AJ,Einstein AJ

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:While treatment guidelines have been developed to guide the management of Staphylococcus aureus bacteraemia, there is a need to validate these guidelines in different clinical settings and to relate the effect of compliance to clinical outcome. AIMS:To assess the impact of adherence to treatment guidelines ...

journal_title：Internal medicine journal

authors： Blyth CC,Darragh H,Whelan A,O'Shea JP,Beaman MH,McCarthy JS

更新日期：2002-05-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：:Individualised drug dosing has been shown to improve patient outcomes and reduce adverse drug events. One method of individualised medicine is the Bayesian approach, which uses prior information about how the population responds to therapy, to inform clinicians about how a specific individual is responding to their cu...

journal_title：Internal medicine journal

authors： Donagher J,Martin JH,Barras MA

更新日期：2017-05-01 00:00:00

abstract：:Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...

journal_title：Internal medicine journal

authors： Pokorny AM,Gittins CB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limits quality of life. The CHA2 DS2 VASc score (congestive heart failure/left ventricular dysfunction, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular d...

journal_title：Internal medicine journal

authors： Mlodawska E,Tomaszuk-Kazberuk A,Lopatowska P,Kaminski M,Musial WJ

更新日期：2017-03-01 00:00:00

abstract：:We documented temporal changes in the use of lipid-lowering medications and achievement of cholesterol targets in an Australian diabetes clinic. The number of patients using lipid-lowering therapy for primary or secondary cardiovascular prevention increased from 6 to 69% between 1993-1995 and 2014-2016, which correspo...

journal_title：Internal medicine journal

authors： Kiburg KV,Ward GM,O'Neal DN,MacIsaac RJ

更新日期：2018-02-01 00:00:00

abstract：:To improve organ donation processes and outcomes, many Australian hospitals have introduced donation after cardiac death (DCD) following the 2010 publication of the National Protocol for DCD. As emergency clinicians play a significant role in identifying potential DCD donors, it is critical to assess their support and...

journal_title：Internal medicine journal

authors： Marck CH,Neate SL,Weiland TJ,Hickey BB,Jelinek GA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Poor sleep is common after stroke, and data regarding its effect on rehabilitation outcomes are limited. Controversial evidence was found concerning the effect of sedatives on improving sleep quality in poor sleepers after stroke. AIM:To assess the prevalence of poor sleep in post-stroke patients and its ef...

journal_title：Internal medicine journal

authors： Iddagoda MT,Inderjeeth CA,Chan K,Raymond WD

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The clinical significance of extreme hyperferritinaemia has come under scrutiny with the increasing recognition of haemophagocytic lymphohistiocytosis (HLH) in adults. Most studies of hyperferritinaemia have focused on serum ferritin greater than 1000 μg/L, often in ambulatory patients. The conditions associ...

journal_title：Internal medicine journal

authors： Wormsbecker AJ,Sweet DD,Mann SL,Wang SY,Pudek MR,Chen LY

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Effective tuberculosis (TB) control relies on early diagnosis and prompt treatment commencement. AIM:To investigate delays in presentation and diagnosis of pulmonary TB (PTB) in a low incidence setting in Western Melbourne. METHODS:A single-centred retrospective observational cohort study of symptomatic pa...

journal_title：Internal medicine journal

authors： Williams E,Cheng AC,Lane GP,Guy SD

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Medical school and resident training programmes offer different learning opportunities and outcomes. The aim of the study was to assess medical student and intern experience in common clinical procedures. METHODS:Interns employed in a metropolitan teaching hospital from 2000 to 2004 completed a survey of ex...

journal_title：Internal medicine journal

authors： Boots RJ,Egerton W,McKeering H,Winter H

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:  Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...

journal_title：Internal medicine journal

authors： Keogh A,Strange G,Kotlyar E,Williams T,Kilpatrick D,Macdonald P,Brown K,Pidoux A,Kermeen F,Steele P,Dalton B,Gabbay E

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Tuberculous lymphadenitis is the commonest form of extrapulmonary tuberculosis. However, the optimal approach to diagnosis, employing biopsy by either fine needle aspiration (FNA) or surgical excision, remains uncertain. AIMS:To evaluate the diagnostic value of biopsy using each of the component diagnostic ...

journal_title：Internal medicine journal

authors： Knox J,Lane G,Wong JS,Trevan PG,Karunajeewa H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Pleural procedures may cause serious complications when incorrectly carried out. There is a need to find effective methods for teaching how to insert a chest drain safely. AIM:To assess the effectiveness of a programme for teaching chest tube insertion using a simulation model (SuperAnnie). METHODS:Groups ...

journal_title：Internal medicine journal

authors： Hutton IA,Kenealy H,Wong C

更新日期：2008-12-01 00:00:00

abstract：:The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by...

journal_title：Internal medicine journal

authors： Lin MS,Dai YS,Pwu RF,Chen YH,Chang NC

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND/AIM:Families, especially in Chinese society, play a crucial role in care provision for relatives with schizophrenia, but the burden of caregiving has shown to cause significant distress among caregivers. The aim of the study is to assess the degree of stress and burden among caregivers of relatives with schi...

journal_title：Internal medicine journal

authors： Wan KF,Wong MMC

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The thiopurines azathioprine and 6-mercaptopurine are recommended for maintenance of remission in inflammatory bowel disease (IBD). Measurement of concentrations of the metabolites 6-thioguanine nucleotide and 6-methylmercaptopurine helps delineate interindividual variation in metabolism that may underlie va...

journal_title：Internal medicine journal

authors： Kennedy NA,Asser TL,Mountifield RE,Doogue MP,Andrews JM,Bampton PA

更新日期：2013-03-01 00:00:00

abstract：:Parathyroid hormone (PTH) is the predominant regulator of calcium/phosphate homeostasis in the human body. Beside this classical function, preclinical and clinical studies indicated a relevant role for PTH in mobilisation of bone marrow-derived cells into peripheral blood. In addition, recombinant PTH (teriparatide) w...

journal_title：Internal medicine journal

authors： Grabmaier U,Huber BC,Franz WM,Koch E,Brunner S

更新日期：2015-08-01 00:00:00

abstract：:Climate change is unequivocal. The fourth assessment report of the Intergovermental Panel on Climate Change has recently projected that global average surface temperature will increase by 1.1 to 6.4 degrees C by 2100. Anthropogenic warming during the twenty-first century would be much greater than that observed in the...

journal_title：Internal medicine journal

authors： Tong S,Mackenzie J,Pitman AJ,FitzGerald G,Nicholls N,Selvey L

更新日期：2008-06-01 00:00:00