Abstract:
:Chronic lead exposure is recognized as a potential cause of hyperuricaemia, kidney damage and hypertension. The fascinating story of lead poisoning and nephrotoxicity illustrates the utility of descriptive studies in the early elucidation of a new disease entity. The pursuit towards understanding lead nephropathy is presented as a successful illustration of human occupational and public health.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Chow KM,Liu ZC,Szeto CCdoi
10.1111/j.1445-5994.2006.01181.xsubject
Has Abstractpub_date
2006-10-01 00:00:00pages
678-82issue
10eissn
1444-0903issn
1445-5994pii
IMJ1181journal_volume
36pub_type
历史文章,杂志文章abstract::Staphylococcal infections are a common and significant clinical problem in medical practice. Most strains of Staphylococcus aureus are now resistant to penicillin, and methicillin-resistant strains of S. aureus (MRSA) are common in hospitals and are emerging in the community. Penicillinase-resistant penicillins (flucl...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1444-0903.2005.00976.x
更新日期:2005-12-01 00:00:00
abstract::Non-invasive ventilation refers to a number of respiratory support strategies commonly used in critical care settings. This paper describes the principles of non-invasive ventilation, the practicalities of its use and the evidence for its use in a number of common acute conditions. ...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2012.02895.x
更新日期:2012-10-01 00:00:00
abstract::Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14987
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Our previous work identified deficiencies in stroke care practices at regional hospitals in comparison to standards suggested by published stroke care guidelines. These deficiencies might be improved by the implementation of clinical pathways. The aim of this study was to assess changes in acute stroke care ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01147.x
更新日期:2006-10-01 00:00:00
abstract::Perhexiline is a prophylactic anti-anginal agent that ameliorates the metabolic basis for myocardial ischaemia and is increasingly used in the management of acute coronary syndromes. No intravenous preparation is available and usual oral loading regimens require 2-3 days to achieve therapeutic drug levels. Two patient...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2004.00624.x
更新日期:2004-06-01 00:00:00
abstract::The author, a physician in late middle age reflects on his own medical career, the aging of those who have taught him and also of those whom he has taught. He describes the sense of ennui and déjà vu. The things that seemed important as a younger doctor seem less important. He has adopted a different paradigm and has ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01256.x
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, enters human cells by binding of its viral protein to the aminopeptidase angiotensin-converting enzyme 2 (ACE2). This has led to speculation whether treatment with renin-angiotensin system (RAS) inhibitors was asso...
journal_title:Internal medicine journal
pub_type: 杂志文章,meta分析
doi:10.1111/imj.15002
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:In Australia medical practitioners are often required to assume the responsibility for assessing fitness to drive. However the clinical practice, knowledge and attitudes of doctors with regards to this responsibility are unknown. The aim of this study was to determine the clinical practice, knowledge and att...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01337.x
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND: Alcoholic liver disease (ALD) is an important contributor to the total burden of alcohol-related harm; however, the morbidity of different types of ALD in Australia has not been described. The aim of this study was to investigate recent trends in hospital admission rates among alcoholic liver cirrhosis, al...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02279.x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The elderly obese are at increased risk of mortality and morbidity of many obesity-related chronic diseases, such as hypertension, diabetes and coronary heart disease. This study was designed to investigate the epidemiological features of overweight and obesity in older rural Chinese. METHODS:A cross-sectio...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01529.x
更新日期:2008-07-01 00:00:00
abstract::Doctor-patient language discordance has been shown to lead to worse clinical outcomes. In this study of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction at an Australian health service, we demonstrated that limited English proficiency (LEP) is an independent predict...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13751
更新日期:2018-04-01 00:00:00
abstract::Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12855
更新日期:2015-10-01 00:00:00
abstract::To improve organ donation processes and outcomes, many Australian hospitals have introduced donation after cardiac death (DCD) following the 2010 publication of the National Protocol for DCD. As emergency clinicians play a significant role in identifying potential DCD donors, it is critical to assess their support and...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12181
更新日期:2013-07-01 00:00:00
abstract::Polycystic ovary syndrome (PCOS) is a prevalent, chronic and heterogeneous endocrine condition, with reproductive, metabolic and psychological features. Insulin resistance and hyperandrogenaemia are the key pathophysiological hormonal abnormalities. Insulin resistance is a significant contributor to the reproductive a...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12495
更新日期:2014-08-01 00:00:00
abstract:AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/imj.12370
更新日期:2014-03-01 00:00:00
abstract::The aim of this study was to collate and evaluate studies investigating either the factors influencing work-related psychological distress in postgraduate year one (PGY1) doctors or the strategies designed to reduce it. This is a systematic review conducted in May 2014. The data sources were key databases (MEDLINE, Ps...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12785
更新日期:2015-10-01 00:00:00
abstract::We review the aetiology of scleroderma from an epidemiological perspective examining genetic, environmental and stochastic risk factors. The presence of familial clustering (but with low twin concordance) suggests a genetic contribution, and this has been confirmed with recent candidate gene and genome-wide associatio...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2011.02706.x
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Myelodysplastic syndrome (MDS), a haematological disorder of the elderly, has been formally classified as a neoplastic disease for 10 years. AIMS:Our aim was to collate national cancer registry incidence data to describe the epidemiology of MDS in New Zealand. METHODS:The New Zealand Cancer Registry has no...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2011.02619.x
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Pulmonary embolism (PE) is associated with significant morbidity and mortality. PE is a heterogeneous entity that causes a wide variety of clinical presentations, making it imperative to establish which clinical symptoms, signs and biomarkers can influence the pretest probability of PE to aid clinicians and ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13596
更新日期:2018-01-01 00:00:00
abstract::Systemic AL amyloidosis is a plasma cell dyscrasia with a characteristic clinical phenotype caused by multi-organ deposition of an amyloidogenic monoclonal protein. This condition poses a unique management challenge due to the complexity of the clinical presentation and the narrow therapeutic window of available thera...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12566
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Magnetic resonance imaging (MRI) accuracy after neoadjuvant systemic therapy (NST) for breast cancer varies according to hormone receptor (HR), human epidermal growth factor receptor type-2 (HER2) subtype and Ki-67 proliferation index. Whether MRI accuracy varies by genomic signatures is unknown. We examined...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/imj.13617
更新日期:2018-06-01 00:00:00
abstract::Young onset dementia (YOD), where symptoms of dementia have an onset before the age of 65, has become more prominent due to the population increase from the Baby Boomer generation. This clinical perspective examines key issues in the assessment, diagnosis and management of YOD. Challenges in the assessment and diagnos...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13099
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Circulating antibodies to glutamic acid decarboxylase (GADab) and tyrosine phosphatase-like molecule IA-2 (IA-2ab) are major indicators for auto-immune destruction of pancreatic islet cells. They identify a majority of Caucasians with type 1 diabetes and approximately 50% of Asians, providing evidence of an ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1444-0903.2004.00482.x
更新日期:2004-01-01 00:00:00
abstract::These consensus guidelines provide recommendations for the safe handling of monoclonal antibodies. Definitive recommendations are given for the minimum safe handling requirements to protect healthcare personnel. The seven recommendations cover: (i) appropriate determinants for evaluating occupational exposure risk; (i...
journal_title:Internal medicine journal
pub_type: 杂志文章,实务指引
doi:10.1111/imj.12564
更新日期:2014-10-01 00:00:00
abstract::Significant developments have occurred in the discipline of palliative care in the modern era. This paper shall explore those developments, challenge some widely held misconceptions about the role and daily practice of the discipline, highlight the growing recognition of the role of palliative care in non-malignant di...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13520
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND AIM:Familial Mediterranean fever (FMF) is an autosomal recessive disease characterised by recurrent episodes of painful inflammation in the abdomen, chest or joints. The association between FMF and non-amyloid glomerulopathies are unusual. In this study, we describe our experiences and observations about...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12520
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Since Hinton first published his observations on the distress of patients dying on a medical ward in 1963, there has been increasing awareness of the palliative care needs in patients who have non malignant diseases. Patients with advanced chronic obstructive pulmonary disease (COPD) are known to have compar...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/imj.12947
更新日期:2016-03-01 00:00:00
abstract::A cross-sectional survey of 265 adult patients with haematological malignancy, haemoglobinopathy or human immunodeficiency virus was performed to determine the potential risk of infection from animal exposures. One hundred and thirty-seven (52%) owned an animal; the majority were dogs (74%) and cats (39%), but 14% own...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13361
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Infections and antibiotic resistance patterns in patients attending regional Australian cancer centres are poorly described. AIMS:To document patient characteristics, infection types, patterns of antibiotic resistance and outcomes in all patients with cancer requiring inpatient management for suspected infe...
journal_title:Internal medicine journal
pub_type: 信件
doi:10.1111/imj.13646
更新日期:2018-03-01 00:00:00
abstract::Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14137
更新日期:2018-12-01 00:00:00