Abstract:
:The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by multivariate analysis. The analysis was based on 35 cases and 105 controls. This study showed that the use of carbamazepine, phenytoin and allopurinol is most associated with the risks in the oriental population.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Lin MS,Dai YS,Pwu RF,Chen YH,Chang NCdoi
10.1111/j.1445-5994.2005.00790.xkeywords:
subject
Has Abstractpub_date
2005-03-01 00:00:00pages
188-90issue
3eissn
1444-0903issn
1445-5994pii
IMJ790journal_volume
35pub_type
杂志文章abstract:BACKGROUND:Long-term prognosis of acute coronary syndromes (ACS) in human immunodeficiency virus (HIV)-infected patients is unknown. AIMS:To compare outcomes after ACS in HIV-infected and uninfected patients. METHODS:Retrospective observational study. HIV cases were matched with two HIV-uninfected controls for age, s...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14744
更新日期:2020-12-01 00:00:00
abstract::Severe sepsis is defined as organ dysfunction in the setting of systemic inflammatory response due to infection. With changes in population age, comorbidity and the delivery of medical care, severe sepsis is increasingly common, and can present in every area of the hospital. The major obstacles to improved outcomes in...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2010.02383.x
更新日期:2011-01-01 00:00:00
abstract:AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/imj.12370
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The aim of the study was to assess the structural and functional effects of autologous stem cell transplantation (ASCT) on scleroderma finger clawing. METHODS:Using photocopies of hands of five scleroderma patients who underwent ASCT using photocopies of hands. Functional assessments used a standardized que...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01593.x
更新日期:2008-09-01 00:00:00
abstract::The indication for permanent pacemaker remains controversial in malignant neurocardiogenic syncope. A highly reproducible prolonged pause during a repeat head-up tilt-table testing may identify a subgroup of neurally mediated syncope with a prominent and consistent cardioinhibitory component. Seven patients (3 females...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1444-0903.2004.00626.x
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Secondary prevention of ischaemic stroke (IS) and transient ischaemic attack (TIA) mandates identification and treatment of multiple metabolic risk factors. The aim was to determine the prevalence of abnormal glycaemia, hypertension and dyslipidaemia in patients presenting to an Acute Stroke Unit of a tertia...
journal_title:Internal medicine journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1445-5994.2009.01941.x
更新日期:2010-04-01 00:00:00
abstract:AIMS:Our primary aim was to determine the rate of overseas travel in immunocompromised individuals attending appropriate clinics at an Australian tertiary care hospital. We also aimed to characterise health-seeking behaviour prior to travel and investigated sources of pre-travel advice, compared travel patterns and act...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12753
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:A Resuscitation Plan is a medically authorised order to use or withhold resuscitation interventions. Absence of appropriate resuscitation orders exposes patients to the risk of invasive medical interventions that may be of questionable benefit depending on individual circumstances. AIMS:To describe among ju...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14994
更新日期:2020-07-20 00:00:00
abstract::Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02366.x
更新日期:2011-08-01 00:00:00
abstract::Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14987
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:In Australia, antimicrobial stewardship programmes are a compulsory component of hospital accreditation. Good documentation around anti-microbial prescribing aids communication and can improve prescribing practice in environments with multiple decision makers. AIM:This study aims to develop and implement an...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12539
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Numerous studies have shown differences in pain perception between men and women, which may affect pain management strategies. AIM:Our primary aim was to investigate whether there are gender-based differences in pain management in patients admitted to our emergency department with acute, non-specific abdomi...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02255.x
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The short Synacthen test is widely used to assess the hypothalamus pituitary adrenal axis in the outpatient setting. In the inpatient setting however, technical difficulties to adhere to the protocol may pose a challenge for using this test. AIMS:In this study we attempted to find the most suitable basal se...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.15033
更新日期:2020-08-24 00:00:00
abstract::The annual Leonard Ball Orations illustrate changing perspectives in Australia over 30 years on medical and social effects of misuse of alcohol and other substances. The first oration, in 1968, examined causal factors in the context of 'agent', 'purveyor' and 'host' and provided themes for subsequent orators. In regar...
journal_title:Internal medicine journal
pub_type: 历史文章,杂志文章
doi:10.1046/j.1445-5994.2001.00068.x
更新日期:2001-08-01 00:00:00
abstract::Imatinib mesylate (IM) is currently used as the first therapeutic choice against chronic myelogenous leukaemia (CML). Because IM poorly penetrates the blood-brain barrier, IM-treated CML patients may have a potential risk of central nervous system (CNS) involvement. Here we report a case with lymphoid blast crisis iso...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2009.01947.x
更新日期:2009-06-01 00:00:00
abstract::Undiagnosed pheochromocytoma in pregnancy is associated with significant maternal and foetal mortality. Herein we reviewed five cases of pheochromocytoma in pregnancy occurring during late pregnancy. The mean age at presentation was 30.6 years, and the gestational age ranged from 26 to 36 weeks. All patients had eleva...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12118
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limits quality of life. The CHA2 DS2 VASc score (congestive heart failure/left ventricular dysfunction, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular d...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13319
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Stroke neurologists, vascular surgeons, interventional neuroradiologists and interventional cardiologists have embraced carotid angioplasty and stenting (CAS) because of potential advantages over carotid endarterectomy (CEA). At Austin Health, a multidisciplinary neuro-interventional group was formed to stan...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02285.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Early involvement of palliative care and advance care planning improves quality of life outcomes and survival for patients with advanced lung cancer, however there are barriers to implementation. AIMS AND METHODS:A single-centre prospective audit reviewing "Goals of Care" (GOC) form completion and palliativ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14817
更新日期:2020-03-23 00:00:00
abstract::Waldenström macroglobulinaemia (WM) is an indolent B-cell malignancy characterised by the presence of immunoglobulin M (IgM) paraprotein and bone marrow infiltration by clonal small B lymphocytes, plasmacytoid lymphocytes and plasma cells. The symptoms of WM are protean, often follow an asymptomatic phase and may incl...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13311
更新日期:2017-01-01 00:00:00
abstract::To share our experience of establishing an acute outreach service to nursing homes and to evaluate the impact of such service on emergency department presentations, data were drawn from a pre-existing database from 2013 to 2017. Of the 986 acute patients treated in 12 nursing homes over a 23-month period, the acute ge...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/imj.14104
更新日期:2018-11-01 00:00:00
abstract::A 22-year-old woman presented with methanol toxicity manifesting as headache, reduced conscious state and visual change after consuming home-made grappa. She progressed to a coma with fixed mydriasis and severe acidaemia (pH 6.55). She was treated with empirical antidote administration (intravenous ethanol) and enhanc...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13725
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:High concentration oxygen is commonly administered during acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of this study was to determine the association between oxygen, severity markers and poor outcomes in AECOPD. METHODS:In an audit of patients with AECOPD arriving by ambula...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02207.x
更新日期:2011-08-01 00:00:00
abstract:AIM:To develop a well-tolerated outpatient chemotherapy regimen for hormone-insensitive prostate cancer. METHOD:Forty patients received carboplatin 20 mg/m2 by continuous ambulatory infusion with oral etoposide 50 mg/day for 21 days repeated every 6 weeks. RESULTS:Four patients had a partial response and 16 patients ...
journal_title:Internal medicine journal
pub_type: 临床试验,杂志文章
doi:10.1111/j.1445-5994.2005.00864.x
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Advanced training in gastroenterology currently consists of 2 years of core training and 1 elective (non-core) year. We surveyed gastroenterologists 2-7 years following completion of training to determine the strengths and weaknesses of their training. METHODS:All gastroenterologists were invited to partici...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2012.02757.x
更新日期:2013-04-01 00:00:00
abstract::The enthusiasm for evidence-based medicine (EBM) has not been accompanied by the same success in bridging the gap between theory and practice. This paper advances the hypothesis that the phenomenon psychologists call hypocognition may hinder the development of EBM. People tend to respond to frames rather than to facts...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2009.02086.x
更新日期:2010-01-01 00:00:00
abstract::Significant developments have occurred in the discipline of palliative care in the modern era. This paper shall explore those developments, challenge some widely held misconceptions about the role and daily practice of the discipline, highlight the growing recognition of the role of palliative care in non-malignant di...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13520
更新日期:2017-08-01 00:00:00
abstract::Stereotactic radiation therapy has emerged as an alternative to conventional radiotherapy for treatment of Cushing disease. The aim of this study was to investigate the efficacy and safety of this treatment. Records of patients with Cushing disease treated with stereotactic radiation were reviewed. Seventeen patients ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2012.02903.x
更新日期:2012-10-01 00:00:00
abstract::The negative health effects of the 2003 invasion of Iraq should act as a watershed in the medical profession's approach to violent conflict. ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01319.x
更新日期:2007-04-01 00:00:00
abstract::To improve organ donation processes and outcomes, many Australian hospitals have introduced donation after cardiac death (DCD) following the 2010 publication of the National Protocol for DCD. As emergency clinicians play a significant role in identifying potential DCD donors, it is critical to assess their support and...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12181
更新日期:2013-07-01 00:00:00