Central nervous system is a sanctuary site for chronic myelogenous leukaemia treated with imatinib mesylate.

abstract：:Decompressive hemicraniectomy (DHC) has been shown to reduce mortality in malignant middle cerebral artery (MCA) infarction. Our primary objective was to compare 1-year mortality between patients receiving DHC for malignant MCA infarction at our institution based on hospital of origin. We retrospectively reviewed the ...

journal_title：Internal medicine journal

authors： Smyth D,Weatherall M,Rosemergy I,Woon K,Lanford J

更新日期：2018-10-01 00:00:00

abstract：:Systemic AL amyloidosis is a plasma cell dyscrasia with a characteristic clinical phenotype caused by multi-organ deposition of an amyloidogenic monoclonal protein. This condition poses a unique management challenge due to the complexity of the clinical presentation and the narrow therapeutic window of available thera...

journal_title：Internal medicine journal

authors： Weber N,Mollee P,Augustson B,Brown R,Catley L,Gibson J,Harrison S,Ho PJ,Horvath N,Jaksic W,Joshua D,Quach H,Roberts AW,Spencer A,Szer J,Talaulikar D,To B,Zannettino A,Prince HM

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Advance care planning (ACP) provides patients with the ability to make their decisions known about how they would like to be treated if they lose capacity. Medical practitioners have a key role to play in providing information on ACP to their patients. This research explores their knowledge and attitudes to ...

journal_title：Internal medicine journal

authors： Cartwright C,Montgomery J,Rhee J,Zwar N,Banbury A

更新日期：2014-03-01 00:00:00

abstract：:Environmental exposures in the foetal period may predispose to autoimmunity. Aim of this study is to investigate whether seasonality in birth patterns exists in idiopathic inflammatory myopathies (IIM). We used Stata (StataCorp USA, version 13.0) and the user-written routine command 'circsummarise' to assess birth sea...

journal_title：Internal medicine journal

authors： Woodman R,Hakendorf P,Limaye V

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Current diagnostic tools are inadequate for reliable prediction of prostate cancer (PCa) aggressiveness in patients with localised disease. This results in many patients being exposed to potentially unnecessary invasive treatment and its associated morbidities. In order to develop appropriate treatment strat...

journal_title：Internal medicine journal

authors： Algotar AM,Thompson PA,Ranger-Moore J,Stratton MS,Hsu CH,Ahmann FR,Nagle RB,Stratton SP

更新日期：2012-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was ...

journal_title：Internal medicine journal

authors： Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie B

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Lung cancer accounts for significant morbidity and mortality worldwide. The effect of recent changes in demographics and management on outcomes in Australia has not been clearly defined. AIMS:To compare three consecutive lung cancer cohorts to evaluate emergent differences in diagnosis, management and morta...

journal_title：Internal medicine journal

authors： Denton EJ,Hart D,Wainer Z,Wright G,Russell PA,Conron M

更新日期：2016-08-01 00:00:00

abstract：:Transient ischaemic attack (TIA) if untreated carries a high risk of early stroke and is associated with poorer long-term survival. There have been recent advances in the understanding of TIA, its investigations, management and organisation of services for patient care. Clinically, patients are diagnosed TIA if they h...

journal_title：Internal medicine journal

authors： Phan TG,Sanders L,Srikanth V

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Cancer treatment near end of life is not likely to add meaningful benefit and minimising intervention rates has been promoted as an indicator of quality of care. Population-based analysis of treatment allows comparative analysis of treatment rates and provides insight into patterns of care. AIMS:To report a...

journal_title：Internal medicine journal

authors： Pitson G,Matheson L,Garrard B,Eastman P,Rogers M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Exacerbations requiring hospital admission for chronic obstructive pulmonary disease (COPD) contribute to a decline in health status and are costly to the community. Long-term trends in admissions and associated outcomes are difficult to establish because of frequent readmissions, high case fatality and pote...

journal_title：Internal medicine journal

authors： Geelhoed EA,Brameld KJ,Holman CD,Thompson PJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes (T2D) in young adults is associated with a high risk of diabetes complications. AIMS:To investigated the demography and the emergence of complications of young adults with T2D in the central Auckland region where there has been substantial immigration. METHODS:In total, 310 young adults wit...

journal_title：Internal medicine journal

authors： Beig J,Khanolkar M,Cundy T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Peptide receptor radionuclide therapy with 177 Lu-DOTATATE is a promising treatment for inoperable or metastatic neuroendocrine tumours (NET). In 2015, the NSW Ministry of Health provided funding for 177 Lu-DOTATATE treatment of NET under an evaluation framework. AIMS:To examine the safety and outcomes of N...

journal_title：Internal medicine journal

authors： Lin E,Chen T,Little A,Holliday L,Roach P,Butler P,Hosking E,Bailey E,Elison B,Currow D

更新日期：2019-10-01 00:00:00

abstract：:Growth hormone (GH) replacement therapy was recently recommended by the Pharmaceutical Benefits Advisory Committee (PBAC) for listing on the Pharmaceutical Benefits Scheme for adults with severe GH deficiency and impaired quality of life. This approval was significant for two reasons. First, the application was initia...

journal_title：Internal medicine journal

authors： Lipworth W,Ambler G,Burt MG,Fairchild J,Inder WJ,Werther G,Ho K

更新日期：2018-08-01 00:00:00

abstract：:Prior randomised studies of immunoglobulin replacement therapy have studied mixed populations with or without a history of infections. Immunoglobulin therapy is expensive and in limited supply suggesting that optimising patient selection is of value. In this retrospective study, infection history identified high-risk ...

journal_title：Internal medicine journal

authors： Paxton L,Hawkins C,Crispin P

更新日期：2016-10-01 00:00:00

abstract：:Despite the inclusion of investigator-industry pecuniary and non-pecuniary associations in published clinical trials, the benefit of such disclosures may be limited. Two recent pivotal phase III drug studies that raised conflict of interest issues are discussed. It is recommended that in the future, a firewall should ...

journal_title：Internal medicine journal

authors： Carney SL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Off-label use of rituximab in lupus nephritis is reported to be beneficial. While the optimal dose is unknown, the regimen of four intravenous doses of 375 mg/m(2) is commonly employed, despite expense and potential side-effects. AIM:To investigate the response to single-dose rituximab, added to standard co...

journal_title：Internal medicine journal

authors： Kotagiri P,Martin A,Hughes P,Becker G,Nicholls K

更新日期：2016-08-01 00:00:00

abstract：:Diabetes mellitus (DM) has been found to be associated with cardiovascular disease. The goal of this study is to evaluate the prevalence of asthma in patients with type II DM after adjusting for other comorbid conditions. We used patient treatment files of inpatients' admissions containing discharge diagnosis (Classif...

journal_title：Internal medicine journal

authors： Hashemzadeh M,Movahed MR

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:High inflammatory bowel disease (IBD) rates have been reported in Australasia, but no state-wide studies have yet been performed. AIM:This study estimates the 1-year incidence and point prevalence of IBD in the state of Tasmania, Australia. It also reports clinical outcomes after 12 months of diagnosis in a...

journal_title：Internal medicine journal

authors： Bhatia R,Yeoh SW,Vaz K,Studd C,Wilson J,Bell S,Otahal P,Venn A

更新日期：2019-05-01 00:00:00

abstract：:Both hip fractures and vitamin D (25-hydroxyvitamin D (25-OHD)) deficiency are more common in winter in regions with temperate climates, but few data exist for a sub-tropical climate. In a South East Queensland tertiary hospital over a 7-year period, there were significantly more hip fractures in winter than the other...

journal_title：Internal medicine journal

authors： Lara Alvarez SE,Bell K,Ward N,Cooke C,Inder WJ

更新日期：2019-08-01 00:00:00

abstract：AIM:To study the sputum microbiology of patients admitted to a teaching hospital with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with concomitant pneumonia. METHODS:This was a retrospective study in a tertiary university hospital in Hong Kong. All episodes of AECOPD with pneumonia, patient d...

journal_title：Internal medicine journal

authors： Ko FW,Lam RK,Li TS,Fok JP,Chan MC,Ng TK,Chan DP,Hui DS

更新日期：2005-11-01 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：:Cardiac involvement is not regarded as a feature of Henoch-Schönlein purpura (HSP). We report a patient with HSP who developed significant cardiac symptoms, which resolved with immunosuppression. We review previous cases of HSP with cardiac features, none of which showed a response to treatment, and discuss evidence t...

journal_title：Internal medicine journal

authors： Polizzotto MN,Gibbs SD,Beswick W,Seymour JF

更新日期：2006-05-01 00:00:00

abstract：:Ambulatory care is an important service for patients with the COVID-19 infection especially in a regional area where most of the patients underwent home isolation. Escalation of treatment and timely transition to inpatient care are critical when COVID-19 patients deteriorate. Equally important is ensuring transfer int...

journal_title：Internal medicine journal

authors： Lwin N,Burgess J,Johnston C,Johnson N,Chung S

更新日期：2020-10-01 00:00:00

abstract：:Waldenström macroglobulinaemia (WM) is an indolent B-cell malignancy characterised by the presence of immunoglobulin M (IgM) paraprotein and bone marrow infiltration by clonal small B lymphocytes, plasmacytoid lymphocytes and plasma cells. The symptoms of WM are protean, often follow an asymptomatic phase and may incl...

journal_title：Internal medicine journal

authors： Talaulikar D,Tam CS,Joshua D,Ho JP,Szer J,Quach H,Spencer A,Harrison S,Mollee P,Roberts AW,Horvath N,Lee C,Zannettino A,Brown R,Augustson B,Jaksic W,Gibson J,Kalff A,Johnston A,Trotman J,Kalro A,Grigoriadis G,

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In 2004, the Pharmaceutical Benefits Scheme (PBS) listed infliximab as a subsidised treatment for ankylosing spondylitis (AS). Eligibility to receive this treatment for AS involved fulfilling several criteria. AIM:To examine the medical literature concerning response to tumor necrosis factor (TNF)-alpha inh...

journal_title：Internal medicine journal

authors： Smith MD,Ahern MJ

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Increasing numbers of patients receiving new oral anticoagulants (NOAC) are undergoing elective surgery. The extent to which perioperative interruption of NOAC therapy and use of bridging heparin are concordant with best evidence is uncertain. AIMS:To determine: (i) concordance of NOAC and bridging heparin ...

journal_title：Internal medicine journal

authors： Wamala H,Scott IA,Caney X

更新日期：2017-12-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) is a potentially fatal complication in solid organ and bone marrow transplant patients, with reported incidence of 0.5-3% and mortality of about 75%. To emphasise the importance of early diagnosis and prompt commencement of therapy results in improved clinical outcomes. A retrospective...

journal_title：Internal medicine journal

authors： Nwaba A,MacQuillan G,Adams LA,Garas G,Delriviere L,Augustson B,DeBoer B,Moody H,Jeffrey GP

更新日期：2013-03-01 00:00:00

abstract：:Chronic lead exposure is recognized as a potential cause of hyperuricaemia, kidney damage and hypertension. The fascinating story of lead poisoning and nephrotoxicity illustrates the utility of descriptive studies in the early elucidation of a new disease entity. The pursuit towards understanding lead nephropathy is p...

journal_title：Internal medicine journal

authors： Chow KM,Liu ZC,Szeto CC

更新日期：2006-10-01 00:00:00

abstract：AIMS:The aim of this study was to provide the first population-based descriptions of typical sleep duration and the prevalence of chronic sleep restriction and chronic sleepiness in community-dwelling Australian adults. METHODS:Ten thousand subjects randomly selected from the New South Wales electoral roll, half aged ...

journal_title：Internal medicine journal

authors： Bartlett DJ,Marshall NS,Williams A,Grunstein RR

更新日期：2008-01-01 00:00:00

abstract：:The mortality rate post admission to hospital after successful resuscitation from out-of-hospital cardiac arrest is high, with significant variation between regions and individual institutions. While prehospital factors such as age, bystander cardiopulmonary resuscitation and total cardiac arrest time are known to inf...

journal_title：Internal medicine journal

authors： Stub D,Bernard S,Smith K,Bray JE,Cameron P,Duffy SJ,Kaye DM

更新日期：2012-11-01 00:00:00