Hospital-in-the-Home experience of first 23 COVID-19 patients at a regional NSW hospital.

abstract：:Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...

journal_title：Internal medicine journal

authors： Chen BS,Wong SHC,Hawkins S,Huggins L

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Quick Sepsis-related Organ Failure Assessment (qSOFA) is recommended for use by the most recent international sepsis definition taskforce to identify suspected sepsis in patients outside the Intensive Care Unit (ICU) at risk of adverse outcomes. Evidence of its comparative effectiveness with existing sepsis ...

journal_title：Internal medicine journal

authors： Li L,Rathnayake K,Green M,Shetty A,Fullick M,Walter S,Middleton-Rennie C,Meller M,Braithwaite J,Lander H,Westbrook JI

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:While medications may prolong life and prevent morbidity in older people, adverse effects of polypharmacy are increasingly recognised. As patients age and become frail, prescribing may be expected to focus more on symptom control and minimise potentially harmful preventive medication use that confer little b...

journal_title：Internal medicine journal

authors： Ilango S,Pillans P,Peel NM,Scott I,Gray LC,Hubbard RE

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, enters human cells by binding of its viral protein to the aminopeptidase angiotensin-converting enzyme 2 (ACE2). This has led to speculation whether treatment with renin-angiotensin system (RAS) inhibitors was asso...

journal_title：Internal medicine journal

authors： Koshy AN,Murphy AC,Farouque O,Ramchand J,Burrell LM,Yudi MB

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Unrelated umbilical cord blood has emerged as an alternative stem cell source for allogeneic transplantation for patients with haematological malignancies, but in adults is limited by the low number of stem cells present in banked cord blood units. We report our experience with double cord blood transplants ...

journal_title：Internal medicine journal

authors： Bradstock K,Hertzberg M,Kerridge I,Svennilson J,George B,McGurgan M,Huang G,Antonenas V,Gottlieb D

更新日期：2009-11-01 00:00:00

abstract：:The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by...

journal_title：Internal medicine journal

authors： Lin MS,Dai YS,Pwu RF,Chen YH,Chang NC

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Inequalities in access to renal services and acute care for rural and remote populations in Australia have been described but not quantified. AIM:To describe: the coverage of renal disease management services in rural and remote Australia; and the characteristics of patients who had an aeromedical retrieval...

journal_title：Internal medicine journal

authors： Gardiner FW,Bishop L,Gale L,Harwood A,Teoh N,Lucas RM,Jones M,Laverty M

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:A Resuscitation Plan is a medically authorised order to use or withhold resuscitation interventions. Absence of appropriate resuscitation orders exposes patients to the risk of invasive medical interventions that may be of questionable benefit depending on individual circumstances. AIMS:To describe among ju...

journal_title：Internal medicine journal

authors： Bryant J,Waller A,Pickles R,Hullick C,Price E,White B,Willmott L,Bowman MA,Knight A,Ryall MA,Sanson-Fisher R

更新日期：2020-07-20 00:00:00

abstract：:Influenza vaccination is an important preventative health measure. A significant proportion of general medical inpatients meets indications for annual inactivated influenza vaccination (IIV), as recommended by the Australian National Immunisation Programme. This study explores opportunities to provide IIV to eligible ...

journal_title：Internal medicine journal

authors： Zaman FY,Nagalingam V,Wong C,Khu YL,Teng HWG,Janardan J,Ritchie E,Cheng AC,Aung AK

更新日期：2019-05-01 00:00:00

abstract：:Despite the inclusion of investigator-industry pecuniary and non-pecuniary associations in published clinical trials, the benefit of such disclosures may be limited. Two recent pivotal phase III drug studies that raised conflict of interest issues are discussed. It is recommended that in the future, a firewall should ...

journal_title：Internal medicine journal

authors： Carney SL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND/AIM:Little is known about exposures to low radiation doses in the first trimester of pregnancy and deterministic adverse effects in the offspring, and risks are extrapolated from catastrophic events or from exposures to radiotherapy. The study aimed to assess the foetal and neonatal outcomes of pregnant wome...

journal_title：Internal medicine journal

authors： Choi JS,Han JY,Ahn HK,Ryu HM,Kim MY,Chung JH,An GH,Nava-Ocampo AA

更新日期：2013-05-01 00:00:00

abstract：AIM:To study the sputum microbiology of patients admitted to a teaching hospital with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with concomitant pneumonia. METHODS:This was a retrospective study in a tertiary university hospital in Hong Kong. All episodes of AECOPD with pneumonia, patient d...

journal_title：Internal medicine journal

authors： Ko FW,Lam RK,Li TS,Fok JP,Chan MC,Ng TK,Chan DP,Hui DS

更新日期：2005-11-01 00:00:00

abstract：:A 75-year-old man of Fijian-Indian extraction complained of a 3-year history of progressive right knee pain and stiffness which were limiting his mobility. On examination, multiple hard nodules were palpable in the popliteal fossa and along the path of the quadriceps tendon. The joint line was not tender, knee flexion...

journal_title：Internal medicine journal

authors： Langguth DM,Klestov A,Denaro C

更新日期：2002-08-01 00:00:00

abstract：:(Neo)adjuvant chemotherapy for early stage breast cancer is associated with side-effects, resulting in increased emergency department (ED) presentations. Treatment-related toxicity can affect quality of life, compromise chemotherapy delivery and treatment outcomes, and increase healthcare use. We performed a retrospec...

journal_title：Internal medicine journal

authors： Tang M,Horsley P,Lewis CR

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:There is a global concern that physician-researchers are 'a dying breed'. Recent studies of clinical career choices of Australian medical students and doctors have signalled the rising age of medical graduates, generational shifts in work-life attitudes and increased proportion of female graduates. There are...

journal_title：Internal medicine journal

authors： Mills JMZ,Januszewski AS,Robinson BG,Traill CL,Jenkins AJ,Keech AC

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND/AIM:This study aimed to report the clinical characteristics and outcomes of Australian patients treated with eculizumab for atypical haemolytic uraemic syndrome (aHUS). METHODS:A retrospective cohort study was undertaken of all patients in Australia treated with eculizumab provided in a compassionate access...

journal_title：Internal medicine journal

authors： Mallett A,Hughes P,Szer J,Tuckfield A,Van Eps C,Cambell SB,Hawley C,Burke J,Kausman J,Hewitt I,Parnham A,Ford S,Isbel N

更新日期：2015-10-01 00:00:00

abstract：:Parathyroid hormone (PTH) is the predominant regulator of calcium/phosphate homeostasis in the human body. Beside this classical function, preclinical and clinical studies indicated a relevant role for PTH in mobilisation of bone marrow-derived cells into peripheral blood. In addition, recombinant PTH (teriparatide) w...

journal_title：Internal medicine journal

authors： Grabmaier U,Huber BC,Franz WM,Koch E,Brunner S

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:There is little research and no clear guidelines for clinicians to follow when instructing patients with advanced disease about driving. AIMS:To investigate current practice in providing advice to patients with advanced disease and identify areas of consensus or variation with the Australian driving guideli...

journal_title：Internal medicine journal

authors： Weir N,Fischer A,Good P

更新日期：2017-10-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...

journal_title：Internal medicine journal

authors： Finlayson J,Grey D,Kavanagh L,Witt C

更新日期：2011-08-01 00:00:00

abstract：:In Australia, mutations in epidermal growth factor mutations (EGFR) occur in 15% of patients diagnosed with non-small-cell lung cancer and are found with higher frequency in female, non-smokers of Asian ethnicity. Activating mutations in the EGFR gene are rarely described in SCLC. We present two cases of de novo EGFR ...

journal_title：Internal medicine journal

authors： Thai A,Chia PL,Russell PA,Do H,Dobrovic A,Mitchell P,John T

更新日期：2017-09-01 00:00:00

abstract：:Here we report the case of a 69-year-old Chinese Han woman who presented with liver cirrhosis, diabetes mellitus, skin hyperpigmentation, hyperferritinaemia and high transferrin saturation. Subsequent genetic analyses identified a novel heterozygous mutation (p.Cys326Phe) in the SLC40A1 gene. This is the first report ...

journal_title：Internal medicine journal

authors： Chen SR,Yang LQ,Chong YT,Jie YS,Wu YK,Yang J,Lin GL,Li XH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:There is limited information on the risk of metastatic breast cancer (MBC) to inform younger women, particularly those under 40 years. AIMS:We conducted a retrospective analysis of a population-based cohort study to describe the risk, site and prognosis of MBC in young women under 40 years with an initial d...

journal_title：Internal medicine journal

authors： Tjokrowidjaja A,Lee CK,Houssami N,Lord S

更新日期：2014-08-01 00:00:00

abstract：:The mortality rate post admission to hospital after successful resuscitation from out-of-hospital cardiac arrest is high, with significant variation between regions and individual institutions. While prehospital factors such as age, bystander cardiopulmonary resuscitation and total cardiac arrest time are known to inf...

journal_title：Internal medicine journal

authors： Stub D,Bernard S,Smith K,Bray JE,Cameron P,Duffy SJ,Kaye DM

更新日期：2012-11-01 00:00:00

abstract：:Clarithromycin is the most documented cytochrome P450 3A4 (CYP3A4) inhibitor to cause an adverse interaction with simvastatin. This particular case is of interest as rhabdomyolysis only occurred after an increase in the dose of clarithromycin. The patient developed raised cardiac biomarkers without any obvious cardiac...

journal_title：Internal medicine journal

authors： Page SR,Yee KC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:In an era of growing subspecialisation there has been significant research into the role, determinants and outcomes of outpatient referrals but very little on inpatient specialty referrals from general medical units. AIMS:This study aims to describe and compare the rate of specialty referrals from inpatient...

journal_title：Internal medicine journal

authors： Brown MG,Campbell D,Maydom BW

更新日期：2014-09-01 00:00:00

abstract：:The antibiotic optimisation imperative is now ubiquitous, with national policy frameworks in Organisation for Economic Co-operation and Development (OECD) countries incorporating the requirement for antimicrobial stewardship within healthcare services. Yet in practice, the optimisation agenda often raises complex ethi...

journal_title：Internal medicine journal

authors： Broom J,Broom A,Good P,Lwin Z

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:In Australia, antimicrobial stewardship programmes are a compulsory component of hospital accreditation. Good documentation around anti-microbial prescribing aids communication and can improve prescribing practice in environments with multiple decision makers. AIM:This study aims to develop and implement an...

journal_title：Internal medicine journal

authors： Chaves NJ,Ingram RJ,MacIsaac CM,Buising KL

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:High baseline level of soluble suppression of tumourigenicity 2 (sST2) was an independent predictor of cardiovascular death and heart failure in ST-segment elevation myocardial infarction (STEMI). AIMS:To investigate the value of serum sST2 baseline levels in predicting myocardial reperfusion in patients wi...

journal_title：Internal medicine journal

authors： Bai S,Liu H,Wu H,Wang X,Li R,Li X,Li X,Zhang L,Chen T,Du R

更新日期：2020-08-01 00:00:00

abstract：:Many publications have highlighted a lack of practical competencies in recently qualified interns. Consultation between the University of Queensland and the Medical Education Unit at Redcliffe Hospital identified key areas where intervention could lead to greater work readiness, and the development of a complementary ...

journal_title：Internal medicine journal

authors： Costello J,Livett M,Stride PJ,West M,Premaratne M,Thacker D

更新日期：2010-10-01 00:00:00

abstract：:Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...

journal_title：Internal medicine journal

authors： Pokorny AM,Gittins CB

更新日期：2015-10-01 00:00:00