Abstract:
BACKGROUND:Since Hinton first published his observations on the distress of patients dying on a medical ward in 1963, there has been increasing awareness of the palliative care needs in patients who have non malignant diseases. Patients with advanced chronic obstructive pulmonary disease (COPD) are known to have comparable symptom burden to lung cancer patients and are more likely receive invasive treatment at the end of life than patients with end stage lung cancer. They are also less likely to receive hospice services, and the benefit of such programmes in this key group of patients remain largely unknown, in particular what effect hospice programmes have on hospitalisation. AIMS:(i) To examine any effect of community hospice programmes on hospitalisation in patients with advanced COPD. (ii) To identify any association between utilisation of specific hospice services with hospitalisation. (iii) To describe key peri-mortem outcomes. METHODS:This was a retrospective study of consecutive patients with COPD admitted into community hospice programmes in the greater Wellington region, New Zealand between 1 October 2007 and 31 October 2013. RESULTS:A mean decrease of 2.375 (median decrease of 2; 95% confidence interval 1, 3) hospital admissions over a 12-month period was found after admission into hospice programme (P < 0.0005). CONCLUSION:Community hospice programmes may be associated with reduction in hospitalisation in patients with advanced COPD.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Iupati SP,Ensor BRdoi
10.1111/imj.12947subject
Has Abstractpub_date
2016-03-01 00:00:00pages
295-300issue
3eissn
1444-0903issn
1445-5994journal_volume
46pub_type
杂志文章,多中心研究abstract::A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01406.x
更新日期:2007-08-01 00:00:00
abstract::The prevalence of Helicobacter pylori in Western societies has rapidly declined, as reflected by the consistent decline in peptic ulcer disease. Nevertheless, there remains a cohort of the elderly population with a high prevalence of H. pylori infection. While the benefits of H. pylori eradication for H. pylori-associ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2002.00275.x
更新日期:2002-09-01 00:00:00
abstract::Non-invasive ventilation refers to a number of respiratory support strategies commonly used in critical care settings. This paper describes the principles of non-invasive ventilation, the practicalities of its use and the evidence for its use in a number of common acute conditions. ...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2012.02895.x
更新日期:2012-10-01 00:00:00
abstract::ABSTRACT Treatment of invasive fungal infections is increasingly complex. Amphotericin B deoxycholate has long been the mainstay of treatment. However, there has been increasing recognition of both the propensity for nephro-toxicity in haematology, transplant and intensive care patients as well as its adverse impact o...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1444-0903.2004.00541.x
更新日期:2004-04-01 00:00:00
abstract::Abstract Hyperammonaemic encephalopathy has been infrequently reported after both standard and high-dose chemotherapy for solid and haematological malignancies. It is important to consider this diagnosis for patients with unexplained behaviour changes or encephalopathy and this case report emphasizes this condition an...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2008.01772.x
更新日期:2008-10-01 00:00:00
abstract::Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14987
更新日期:2020-09-01 00:00:00
abstract::Laura was unusual. She had always been different and at times difficult. She was born with a genetic disorder, diagnosed as 1p36 deletion syndrome when she was 21 years old. At 23 she suffered her first cardiac arrest at home and entered the hospital system for the first time apart from infancy. After initially appear...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2012.02878.x
更新日期:2012-09-01 00:00:00
abstract::Despite the inclusion of investigator-industry pecuniary and non-pecuniary associations in published clinical trials, the benefit of such disclosures may be limited. Two recent pivotal phase III drug studies that raised conflict of interest issues are discussed. It is recommended that in the future, a firewall should ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2012.02940.x
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:As direct-to-consumer personal genome testing (DTC-PGT) is increasingly available in Australia, knowledge of Australians' perceptions and attitudes towards this technology is needed in order to assess the (potential) impact it might have on the Australian public and healthcare system. AIMS:To explore the kn...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12289
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Where proven cancer therapies remain unfunded, patients are faced with difficult decisions regarding personally covering some or all of the treatment cost. Clinical trials provide an alternative form of access to unfunded drugs. AIMS:To examine the patient population and utilisation of the colorectal cancer...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2012.02750.x
更新日期:2013-01-01 00:00:00
abstract::The incidence of tuberculosis in the non-indigenous Australian population is low. However, in this paper we report on three cases of cavitating disease, which seem to be associated with a common illicit drug habit namely smoking marijuana using a makeshift pipe or bong. There was a total of 34 positive contacts of the...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12089
更新日期:2013-04-01 00:00:00
abstract::Paradigms for managing acromegaly have undergone major changes in the past two decades. This has been brought about by combining surgical, pharmacological and radiotherapeutic approaches that provide tight biochemical control to reduce mortality to that of the general population. The biochemical targets for treatment ...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2006.01097.x
更新日期:2006-07-01 00:00:00
abstract::Environmental exposures in the foetal period may predispose to autoimmunity. Aim of this study is to investigate whether seasonality in birth patterns exists in idiopathic inflammatory myopathies (IIM). We used Stata (StataCorp USA, version 13.0) and the user-written routine command 'circsummarise' to assess birth sea...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13061
更新日期:2016-05-01 00:00:00
abstract::Conventional teaching on the mechanisms and treatment of spontaneous pneumothorax is either obviously wrong or based on a misunderstanding of the natural history of the condition. Spontaneous pneumothorax is a generally benign, self-limiting condition where conservative management should be considered. If intervention...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2009.02155.x
更新日期:2010-03-01 00:00:00
abstract::Ambulatory care is an important service for patients with the COVID-19 infection especially in a regional area where most of the patients underwent home isolation. Escalation of treatment and timely transition to inpatient care are critical when COVID-19 patients deteriorate. Equally important is ensuring transfer int...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.15016
更新日期:2020-10-01 00:00:00
abstract:AIMS:To measure factors associated with underuse of beta-blocker therapy after myocardial infarction (MI). METHODS:The Newcastle and Perth collaborating centres of the World Health Organization (WHO) MONICA project (to MONItor trends and determinants of Cardiovascular disease) systematically evaluated all patients adm...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2001.00098.x
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Several epidemiological studies have suggested a positive association of coronary heart disease with both Helicobacter pylori and Chlamydia pneumoniae infection. The issue has been difficult to resolve because of the potential impact of several confounding factors, in particular, socioeconomic status for H. ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2003.00349.x
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Extreme heat is a public health priority in Australia with the health effects of cold poorly studied. A record-breaking cold winter prompted an institutional investigation into the epidemiology and outcomes of hypothermic presentations. AIMS:To describe the clinical and epidemiological characteristics of hy...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14308
更新日期:2020-01-01 00:00:00
abstract::The insulin tolerance test is considered the gold standard for assessing the hypothalamic-pituitary-adrenal and growth hormone (GH) axes, but its use varies considerably among different endocrine units. We recommend using the insulin tolerance test to assess the hypothalamic-pituitary-adrenal axis within 3 months of p...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12011
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Inequalities in access to renal services and acute care for rural and remote populations in Australia have been described but not quantified. AIM:To describe: the coverage of renal disease management services in rural and remote Australia; and the characteristics of patients who had an aeromedical retrieval...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14716
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:The international literature advocates for cancer screening in newly diagnosed patients with autoimmune myositis; however, there is no widely accepted consensus or guideline to outline the optimal cancer screening strategy and the evidence is currently insufficient to support any recommendation. AIM:Our stu...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13556
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND: Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1445-5994.2010.02403.x
更新日期:2011-03-01 00:00:00
abstract::The enthusiasm for evidence-based medicine (EBM) has not been accompanied by the same success in bridging the gap between theory and practice. This paper advances the hypothesis that the phenomenon psychologists call hypocognition may hinder the development of EBM. People tend to respond to frames rather than to facts...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2009.02086.x
更新日期:2010-01-01 00:00:00
abstract::Growth hormone (GH) replacement therapy was recently recommended by the Pharmaceutical Benefits Advisory Committee (PBAC) for listing on the Pharmaceutical Benefits Scheme for adults with severe GH deficiency and impaired quality of life. This approval was significant for two reasons. First, the application was initia...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.13943
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Current diagnostic tools are inadequate for reliable prediction of prostate cancer (PCa) aggressiveness in patients with localised disease. This results in many patients being exposed to potentially unnecessary invasive treatment and its associated morbidities. In order to develop appropriate treatment strat...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2011.02473.x
更新日期:2012-04-01 00:00:00
abstract::Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14137
更新日期:2018-12-01 00:00:00
abstract::Changes in medical research ethics in the past two decades have made the communication of risk to potential participants a legal imperative. Using ethnographic data from two different cultures, we examine the hazards associated with medical research in relation to the respective societal contexts that imbue them with ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2003.00460.x
更新日期:2003-09-01 00:00:00
abstract::Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02366.x
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND: Hepatic epithelioid haemangioendothelioma (HEH) is a rare, low grade malignant neoplasm of endothelial origin which is difficult to diagnose and has a variable outcome. We review five HEH cases from our centre with the aim of identifying clinical predictors of outcome and various therapeutic options. METH...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2009.02043.x
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Poor quality prescribing has been identified as one of the leading causes of medication error and adverse drug events. The aim of this study was to improve the quality of written prescriptions in a general hospital by a combination of serial audits and interventions designed to address identified deficiencie...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01518.x
更新日期:2008-04-01 00:00:00