Hypocognition and evidence-based medicine.

abstract：BACKGROUND:Where proven cancer therapies remain unfunded, patients are faced with difficult decisions regarding personally covering some or all of the treatment cost. Clinical trials provide an alternative form of access to unfunded drugs. AIMS:To examine the patient population and utilisation of the colorectal cancer...

journal_title：Internal medicine journal

authors： Tie J,Gibbs P

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:There is no valid cardiovascular disease (CVD) risk prediction equation for Australians with diabetes. The aim of this study is to develop and validate a multivariate risk function for 5-year cardiovascular risk prediction in Australian type 2 diabetes patients. METHODS:The Fremantle Diabetes Study is a com...

journal_title：Internal medicine journal

authors： Davis WA,Knuiman MW,Davis TM

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The NSW Clinical Excellence commission introduced the "Between the Flags" program in response to the death of a young patient as a system wide approach for early detection and management of the deteriorating patient in all 242 NSW hospitals. The impact of BTF implementation on the 35 larger hospitals with IC...

journal_title：Internal medicine journal

authors： Bhonagiri D,Lander H,Green M,Straney L,Jones D,Pilcher D

更新日期：2020-03-04 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Our previous work identified deficiencies in stroke care practices at regional hospitals in comparison to standards suggested by published stroke care guidelines. These deficiencies might be improved by the implementation of clinical pathways. The aim of this study was to assess changes in acute stroke care ...

journal_title：Internal medicine journal

authors： Read SJ,Levy J

更新日期：2006-10-01 00:00:00

abstract：:Australian internal medicine trainees undergo intensive training in preparation for the Royal Australasian College of Physicians (RACP) clinical examination. Trainees preparing for the 2013 RACP clinical examination assessed the jugular venous pressure (JVP) of patients, with central venous pressure monitoring in the ...

journal_title：Internal medicine journal

authors： Sibbin CP,Bihari S,Russell P

更新日期：2016-09-01 00:00:00

abstract：:Prior randomised studies of immunoglobulin replacement therapy have studied mixed populations with or without a history of infections. Immunoglobulin therapy is expensive and in limited supply suggesting that optimising patient selection is of value. In this retrospective study, infection history identified high-risk ...

journal_title：Internal medicine journal

authors： Paxton L,Hawkins C,Crispin P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Escalating morbidity and mortality associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infections represent a major health burden in Australia, particularly among migrants from endemic areas who may present late. METHODS AND AIMS:We evaluated the knowledge and educational needs of general pr...

journal_title：Internal medicine journal

authors： Guirgis M,Yan K,Bu YM,Zekry A

更新日期：2012-05-01 00:00:00

abstract：:The prevalence of Helicobacter pylori in Western societies has rapidly declined, as reflected by the consistent decline in peptic ulcer disease. Nevertheless, there remains a cohort of the elderly population with a high prevalence of H. pylori infection. While the benefits of H. pylori eradication for H. pylori-associ...

journal_title：Internal medicine journal

authors： Duggan A

更新日期：2002-09-01 00:00:00

abstract：:There is evidence of the increasing use of complementary and alternative medicine by Australians diagnosed with cancer. Given the increasing desire of cancer patients to use complementary and alternative medicine, it is important that clinicians have a good understanding of the evidence available in this field. This c...

journal_title：Internal medicine journal

authors： Joske DJ,Rao A,Kristjanson L

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Immunohistochemistry for loss of expression of one or more of the mismatch repair proteins is performed on colorectal cancer tissue as a screening test for Lynch syndrome; however, its role in pre-malignant polyps remains controversial. AIM:To determine the effectiveness of mismatch repair immunohistochemis...

journal_title：Internal medicine journal

authors： Dow E,Buchanan DD,Winship IM

更新日期：2018-11-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) haplogroups are 'neutral polymorphisms' in the mtDNA genome, which have accumulated and persisted along maternal lineages as the human population has migrated worldwide. Three ethnically distinct lineages of human mtDNA populations have been identified: European, characterized by nine haplogr...

journal_title：Internal medicine journal

authors： Manwaring N,Jones MM,Wang JJ,Rochtchina E,Mitchell P,Sue CM

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:  Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...

journal_title：Internal medicine journal

authors： Keogh A,Strange G,Kotlyar E,Williams T,Kilpatrick D,Macdonald P,Brown K,Pidoux A,Kermeen F,Steele P,Dalton B,Gabbay E

更新日期：2011-03-01 00:00:00

abstract：AIMS:We sought to assess a broad array of possible precipitants of acute coronary syndromes (ACS) and evaluate their association with detectable inflammatory activation. METHODS AND RESULTS:Within a case-crossover design, using a standardised questionnaire, interviews among 348 ST-elevation myocardial infarction (44%)...

journal_title：Internal medicine journal

authors： Chew DP,Mattschoss S,Horsfall M,Astley C,Vaile JC,Joseph MX

更新日期：2012-10-01 00:00:00

abstract：:Advanced heart failure represents a small proportion of patients with heart failure that possess high-risk features associated with high hospital readmission rates, significant functional impairment and mortality. Identification of those who have progressed to, or are near a state of advanced heart failure should prom...

journal_title：Internal medicine journal

authors： Stokes MB,Bergin P,McGiffin D

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The altered status of iron metabolism is reported in hereditary haemochromatosis and in non-alcoholic liver fatty disease. We investigated the relation between the H63D HFE mutation gene and non-alcoholic steatohepatitis (NASH). METHODS:We studied as outpatients, 272 Italian persons with NASH and compared t...

journal_title：Internal medicine journal

authors： Neri S,Pulvirenti D,Signorelli S,Ignaccolo L,Tsami A,Mauceri B,Misseri M,Interlandi D,Cutuli N,Castellino P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The parenteral administration of oestradiol acutely protects against exercise-induced myocardial ischaemia in women, but whether this effect is sex-specific is not known. AIMS:The effects of acutely administered conjugated equine oestrogen on exercise-induced myocardial ischaemia in men with established cor...

journal_title：Internal medicine journal

authors： Davis SR,Bradbury J,Bell R,Johns JA

更新日期：2003-05-01 00:00:00

abstract：:A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...

journal_title：Internal medicine journal

authors： Sharma R,Koller L,Barclay P,Liddle C

更新日期：2007-08-01 00:00:00

abstract：:Multiple myeloma is an incurable malignancy of plasma cells. We retrospectively reviewed the survival outcomes of patients with multiple myeloma in Western Australia (WA) public hospitals over a 10-year period. We did not detect a difference in survival between patients residing the metropolitan Perth and regional are...

journal_title：Internal medicine journal

authors： Ng TF,Burrow S,Leahy M,Augustson B,Trentino K,De Kraa R,Wright M,Carnley B

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:In an era of growing subspecialisation there has been significant research into the role, determinants and outcomes of outpatient referrals but very little on inpatient specialty referrals from general medical units. AIMS:This study aims to describe and compare the rate of specialty referrals from inpatient...

journal_title：Internal medicine journal

authors： Brown MG,Campbell D,Maydom BW

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:There is no mechanism in place for monitoring or quality improvement of cancer multidisciplinary meetings (MDM) in Australia. AIM:To develop a peer-review process for quality improvement of MDM. METHODS:This project involved three phases: (i) development of a draft peer-review framework, supporting documen...

journal_title：Internal medicine journal

authors： Johnson CE,Slavova-Azmanova N,Saunders C

更新日期：2017-05-01 00:00:00

abstract：:Minimisation of radiation exposure with cardiac imaging reduces the potential of secondary side effects. Radiation exposure from myocardial perfusion scintigraphy and computed tomography coronary angiography (CTCA) was compared. Overall doses were low with both modalities. Doses were lower in the CTCA group, but by on...

journal_title：Internal medicine journal

authors： Tsay IM,Subiakto I,Asrar Ul Haq M,Castles AV,Allman K,Hayat U,Rudd N,Barlis P,van Gaal W

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:  Hepatic epithelioid haemangioendothelioma (HEH) is a rare, low grade malignant neoplasm of endothelial origin which is difficult to diagnose and has a variable outcome. We review five HEH cases from our centre with the aim of identifying clinical predictors of outcome and various therapeutic options. METH...

journal_title：Internal medicine journal

authors： Thin LW,Wong DD,De Boer BW,Ferguson JM,Adams L,Macquillan G,Delriviere L,Mitchell A,Jeffrey GP

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Advanced physician training in clinical pharmacology lacks a continuing education programme. There is a need for continuing medical education but how to introduce and develop education remains unclear. AIMS:The primary aim was to develop and implement a peer-led, web-based multiple choice question approach ...

journal_title：Internal medicine journal

authors： Athavale A,Murnion B

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Rhabdomyolysis (RB) is a syndrome characterised by decomposition of skeletal muscle that could be life threatening, so the identification of biomarkers of its severity could help us in its treatment. Creatine kinase (CK) is usually taken as a reference in patients with RB in order to stratify prognosis, howe...

journal_title：Internal medicine journal

authors： Baeza-Trinidad R,Brea-Hernando A,Morera-Rodriguez S,Brito-Diaz Y,Sanchez-Hernandez S,El Bikri L,Ramalle-Gomara E,Garcia-Alvarez JL

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF), an important and treatable cause of ischaemic stroke, can occur as a sustained or a paroxysmal arrhythmia. Continuous cardiac rhythm monitoring (Holter monitoring) is often performed in stroke patients to identify paroxysmal AF, which is an indication for warfarin anti-coagulation i...

journal_title：Internal medicine journal

authors： Shafqat S,Kelly PJ,Furie KL

更新日期：2004-06-01 00:00:00

abstract：:Environmental exposures in the foetal period may predispose to autoimmunity. Aim of this study is to investigate whether seasonality in birth patterns exists in idiopathic inflammatory myopathies (IIM). We used Stata (StataCorp USA, version 13.0) and the user-written routine command 'circsummarise' to assess birth sea...

journal_title：Internal medicine journal

authors： Woodman R,Hakendorf P,Limaye V

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Current diagnostic tools are inadequate for reliable prediction of prostate cancer (PCa) aggressiveness in patients with localised disease. This results in many patients being exposed to potentially unnecessary invasive treatment and its associated morbidities. In order to develop appropriate treatment strat...

journal_title：Internal medicine journal

authors： Algotar AM,Thompson PA,Ranger-Moore J,Stratton MS,Hsu CH,Ahmann FR,Nagle RB,Stratton SP

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The elderly obese are at increased risk of mortality and morbidity of many obesity-related chronic diseases, such as hypertension, diabetes and coronary heart disease. This study was designed to investigate the epidemiological features of overweight and obesity in older rural Chinese. METHODS:A cross-sectio...

journal_title：Internal medicine journal

authors： Zhang X,Sun Z,Zhang X,Zheng L,Liu S,Xu C,Li J,Zhao F,Li J,Hu D,Sun Y

更新日期：2008-07-01 00:00:00

abstract：:Climate change is unequivocal. The fourth assessment report of the Intergovermental Panel on Climate Change has recently projected that global average surface temperature will increase by 1.1 to 6.4 degrees C by 2100. Anthropogenic warming during the twenty-first century would be much greater than that observed in the...

journal_title：Internal medicine journal

authors： Tong S,Mackenzie J,Pitman AJ,FitzGerald G,Nicholls N,Selvey L

更新日期：2008-06-01 00:00:00