Cannula-associated Staphylococcus aureus bacteraemia: outcome in relation to treatment.

Abstract:

BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHODS:We prospectively studied 276 patients with CASAB. Patients were followed for at least 8 weeks after completion of antibiotic treatment. Initial and subsequent isolates of S. aureus were compared using molecular methods to determine strain similarity. RESULTS:Initial mortality was 9% (26 of 276) and a complicating focus of infection presented during initial treatment in 6% (15 of 250) of the survivors. There were nine relapses of deep-seated infection from the strain causing the original infection. Relapses were equally common following peripheral CASAB and central CASAB. There was no relationship between the duration of treatment and the rate of relapse of deep-seated infection (P = 0.24). This observation held true regardless of whether the duration of treatment was analysed as < or = 7 versus > or = 8, < or =10 versus > or =11, or < or=14 versus > or =15 days (P = 0.62, 0.87 and 0.16, respectively). CONCLUSION:Episodes of peripheral CASAB pose an equal risk of relapse to central cannula-related episodes. Although further studies are needed to determine the optimal treatment of CASAB, our study strongly suggests that more than 14 days treatment is excessive for most patients who respond promptly to cannula removal and antibiotic treatment.

journal_name

Intern Med J

authors

Thomas MG,Morris AJ

doi

10.1111/j.1445-5994.2005.00823.x

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

319-30

issue

6

eissn

1444-0903

issn

1445-5994

pii

IMJ823

journal_volume

35

pub_type

杂志文章
  • Placental involvement by non-Hodgkin lymphoma in a Crohn disease patient on long-term thiopurine therapy.

    abstract::We report the first published case of aggressive diffuse large B-cell (non-Hodgkin) lymphoma in a 35-year-old pregnant woman who had Crohn disease and was taking long-term thiopurine therapy: the patient developed placental insufficiency, and there was intrauterine fetal death. ...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.12957

    authors: Chen G,Crispin P,Cherian M,Dahlstrom JE,Sethna FF,Kaye G,Pavli P,Subramaniam K

    更新日期:2016-01-01 00:00:00

  • Prevalence and management of HER2/neu-positive early breast cancer in a single institution following availability of adjuvant trastuzumab.

    abstract:AIM:To ascertain the prevalence of HER2/neu-positive early breast cancer (EBC), utilisation of adjuvant trastuzumab and incidence of cardiac toxicity in a community private hospital setting. METHODS:Prospective data collected by breast oncologist and surgeons in all women diagnosed with EBC at the Mount Hospital (MH) ...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2011.02432.x

    authors: Chan A,McGregor SR

    更新日期:2012-03-01 00:00:00

  • Immediate cephalosporin allergy.

    abstract:BACKGROUND:Patients who suffer from acute IgE-mediated allergy to a cephalosporin antibiotic are frequently assumed to be at high risk of allergy to other cephalosporins and penicillins. AIM:To define cross-reactivity patterns in patients with confirmed allergy to a cephalosporin. METHODS:Subjects presenting with a h...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.14229

    authors: Yuson C,Kumar K,Le A,Ahmadie A,Banovic T,Heddle R,Kette F,Smith W,Hissaria P

    更新日期:2019-08-01 00:00:00

  • Echocardiography for the clinician: a practical update.

    abstract::Echocardiography is the mainstay of cardiovascular diagnostics, and is the most performed test for the evaluation of cardiac function. Critical and costly management decisions are based on quantification of left ventricular volumes and ejection fraction. Recent advances in echocardiography, such as microsphere contras...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-5994.2010.02167.x

    authors: Hudaverdi M,Hamilton-Craig C,Platts D,Chan J,Burstow DJ

    更新日期:2010-07-01 00:00:00

  • Impact of limited English proficiency on presentation and outcomes of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.

    abstract::Doctor-patient language discordance has been shown to lead to worse clinical outcomes. In this study of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction at an Australian health service, we demonstrated that limited English proficiency (LEP) is an independent predict...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.13751

    authors: Biswas S,Seman M,Cox N,Neil C,Brennan A,Dinh D,Walton A,Chan W,Lefkovits J,Reid C,Stub D

    更新日期:2018-04-01 00:00:00

  • Donation after cardiac death: are Australian emergency clinicians supportive?

    abstract::To improve organ donation processes and outcomes, many Australian hospitals have introduced donation after cardiac death (DCD) following the 2010 publication of the National Protocol for DCD. As emergency clinicians play a significant role in identifying potential DCD donors, it is critical to assess their support and...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.12181

    authors: Marck CH,Neate SL,Weiland TJ,Hickey BB,Jelinek GA

    更新日期:2013-07-01 00:00:00

  • Non-invasive ventilation in critical care.

    abstract::Non-invasive ventilation refers to a number of respiratory support strategies commonly used in critical care settings. This paper describes the principles of non-invasive ventilation, the practicalities of its use and the evidence for its use in a number of common acute conditions. ...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-5994.2012.02895.x

    authors: Cross AM

    更新日期:2012-10-01 00:00:00

  • Hyperammonaemic encephalopathy associated with rituximab-containing chemotherapy.

    abstract::Abstract Hyperammonaemic encephalopathy has been infrequently reported after both standard and high-dose chemotherapy for solid and haematological malignancies. It is important to consider this diagnosis for patients with unexplained behaviour changes or encephalopathy and this case report emphasizes this condition an...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2008.01772.x

    authors: Nott L,Price TJ,Pittman K,Patterson K,Young R,Fletcher J

    更新日期:2008-10-01 00:00:00

  • Unrelated umbilical cord blood transplantation for adults with haematological malignancies: results from a single Australian centre.

    abstract:BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2006.01079.x

    authors: Bradstock KF,Hertzberg MS,Kerridge IH,Svennilson J,McGurgan M,Huang G,Antonenas V,Gottlieb DJ

    更新日期:2006-06-01 00:00:00

  • Improving the quality of written prescriptions in a general hospital: the influence of 10 years of serial audits and targeted interventions.

    abstract:BACKGROUND:Poor quality prescribing has been identified as one of the leading causes of medication error and adverse drug events. The aim of this study was to improve the quality of written prescriptions in a general hospital by a combination of serial audits and interventions designed to address identified deficiencie...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2007.01518.x

    authors: Gommans J,McIntosh P,Bee S,Allan W

    更新日期:2008-04-01 00:00:00

  • Clinical outcomes in patients with advanced epidermal growth factor receptor-mutated non-small-cell lung cancer in South Western Sydney Local Health District.

    abstract:BACKGROUND:Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) is a subgroup of oncogene addicted lung cancer that predicts response to tyrosine kinase inhibitors (TKI). However, there is variability in response and survival outcomes in patients with EGFR mutation treated with TKI. AIM:T...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.13555

    authors: Ding PN,Roberts TL,Chua W,Becker TM,Descallar J,Yip PY,Bray V

    更新日期:2017-12-01 00:00:00

  • Evaluation of the off-label usage of rituximab in a large teaching hospital in New South Wales.

    abstract::A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2007.01406.x

    authors: Sharma R,Koller L,Barclay P,Liddle C

    更新日期:2007-08-01 00:00:00

  • Use of brentuximab vedotin as salvage therapy pre-allogeneic stem cell transplantation in relapsed/refractory CD30 positive lympho-proliferative disorders: a single centre experience.

    abstract:BACKGROUND:The role of brentuximab peri-allogeneic transplantation in patients with relapsed and/or refractory CD30 positive lymphomas remains poorly defined. AIM:To assess the outcome of use of brentuximab as a bridge to allogeneic stem cell transplantation (SCT) in patient with relapsed/refractory CD30+ classic Hodg...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.13415

    authors: Mediwake H,Morris K,Curley C,Butler J,Kennedy G

    更新日期:2017-05-01 00:00:00

  • Hypomagnesaemia linked to depression: a systematic review and meta-analysis.

    abstract:BACKGROUND:The reported risk of depression in patients with hypomagnesaemia is controversial. AIM:The objective of this meta-analysis was to assess the association between depression and hypomagnesaemia. METHODS:A literature search was performed using MEDLINE, EMBASE, Cochrane Database and clinicaltrials.gov from inc...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/imj.12682

    authors: Cheungpasitporn W,Thongprayoon C,Mao MA,Srivali N,Ungprasert P,Varothai N,Sanguankeo A,Kittanamongkolchai W,Erickson SB

    更新日期:2015-04-01 00:00:00

  • Vaccination and screening for infections in patients with inflammatory bowel disease: a survey of Australian gastroenterologists.

    abstract:AIMS:To survey the practice among gastroenterologists in Australia relating to screening for latent infections and vaccination of patients with inflammatory bowel disease prior to treatment with tumour necrosis factor alpha (TNF-α) inhibitors. METHODS:A structured 15 question electronic survey was advertised to gastro...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2009.02114.x

    authors: Gupta A,Macrae FA,Gibson PR

    更新日期:2011-06-01 00:00:00

  • Leprosy: diagnosis and management in a developed setting.

    abstract::Leprosy remains an important global health concern, but little has been published about its diagnosis and management in developed settings. It has been postulated that delay in diagnosis is common in developed settings. We reviewed all the cases of leprosy seen at a major tertiary referral centre between 1999 and 2013...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,评审

    doi:10.1111/imj.12638

    authors: Turner D,McGuinness SL,Leder K

    更新日期:2015-01-01 00:00:00

  • Utility of immunohistochemistry for mismatch repair proteins on colorectal polyps in the familial cancer clinic.

    abstract:BACKGROUND:Immunohistochemistry for loss of expression of one or more of the mismatch repair proteins is performed on colorectal cancer tissue as a screening test for Lynch syndrome; however, its role in pre-malignant polyps remains controversial. AIM:To determine the effectiveness of mismatch repair immunohistochemis...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.13953

    authors: Dow E,Buchanan DD,Winship IM

    更新日期:2018-11-01 00:00:00

  • A will and a way to fund medicines for rare diseases: the story of human growth hormone replacement for adults with growth hormone deficiency.

    abstract::Growth hormone (GH) replacement therapy was recently recommended by the Pharmaceutical Benefits Advisory Committee (PBAC) for listing on the Pharmaceutical Benefits Scheme for adults with severe GH deficiency and impaired quality of life. This approval was significant for two reasons. First, the application was initia...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,评审

    doi:10.1111/imj.13943

    authors: Lipworth W,Ambler G,Burt MG,Fairchild J,Inder WJ,Werther G,Ho K

    更新日期:2018-08-01 00:00:00

  • Characteristics of Queensland physicians and the influence of rural exposure on practice location.

    abstract::The Queensland branch of the Royal Australasian College of Physicians (RACP) commissioned this study to update their workforce profile and examine rural practice. The present investigation aimed to describe characteristics of Queensland physicians and determine the influence of childhood and training locations on curr...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.13156

    authors: Runge CE,MacKenzie A,Loos C,Waller M,Gabbett M,Mills R,Eley D

    更新日期:2016-08-01 00:00:00

  • Upper gastrointestinal bleeding in neck of femur fracture patients: a single tertiary centre experience.

    abstract::This study aimed to identify the incidence of perioperative acute upper gastrointestinal bleeding (UGIB) in our hip fracture patients; to evaluate the characteristics, management and clinical outcomes of these patients; and to explore risk factors and protective factors. Of the 1691 consecutive patients admitted for s...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.13809

    authors: Liu J,Gupta R,Hay K,Pulle C,Rahman T,Pandy S

    更新日期:2018-06-01 00:00:00

  • Consensus guidelines for 'rainy day' autologous stem cell harvests in New South Wales.

    abstract::Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2008.01632.x

    authors: Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

    更新日期:2008-04-01 00:00:00

  • Stress and burden faced by family caregivers of people with schizophrenia and early psychosis in Hong Kong.

    abstract:BACKGROUND/AIM:Families, especially in Chinese society, play a crucial role in care provision for relatives with schizophrenia, but the burden of caregiving has shown to cause significant distress among caregivers. The aim of the study is to assess the degree of stress and burden among caregivers of relatives with schi...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,多中心研究

    doi:10.1111/imj.14166

    authors: Wan KF,Wong MMC

    更新日期:2019-03-01 00:00:00

  • Infections, resistance patterns and antibiotic use in patients at a regional cancer centre.

    abstract:BACKGROUND:Infections and antibiotic resistance patterns in patients attending regional Australian cancer centres are poorly described. AIMS:To document patient characteristics, infection types, patterns of antibiotic resistance and outcomes in all patients with cancer requiring inpatient management for suspected infe...

    journal_title:Internal medicine journal

    pub_type: 信件

    doi:10.1111/imj.13646

    authors: De Silva N,Jackson J,Steer C

    更新日期:2018-03-01 00:00:00

  • Clinical features of Fabry's disease in Australian patients.

    abstract:BACKGROUND:Anticipating the prospect of specific treatment, we studied a large group of Australians with Fabry's disease. AIMS:We aimed to: (i) document the clinical features of Fabry's disease in Australian patients, (ii) test the hypothesis that clinical features vary with specific mutation and blood group and (iii)...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1046/j.1445-5994.2002.00291.x

    authors: Galanos J,Nicholls K,Grigg L,Kiers L,Crawford A,Becker G

    更新日期:2002-12-01 00:00:00

  • Survey of antifungal prophylaxis and fungal diagnostic tests employed in malignant haematology and haemopoietic stem cell transplantation (HSCT) in Australia and New Zealand.

    abstract::This article reports the findings of a survey developed to assess the current use of antifungal prophylaxis among haematology and infectious disease clinicians across Australia and New Zealand, and their alignment with existing consensus guidelines for the use of antifungal agents in the haematology/oncology setting (...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,评审

    doi:10.1111/imj.12594

    authors: van Hal SJ,Gilroy NM,Morrissey CO,Worth LJ,Szer J,Tam CS,Chen SC,Thursky KA,Slavin MA

    更新日期:2014-12-01 00:00:00

  • Carbimazole-induced agranulocytosis: does antineutrophil cytoplasmic antibody have a role?

    abstract::Carbimazole is a drug that is widely used for hyperthyroid disorders, such as Graves' disease. Agranulocytosis is a rare idiosyncratic adverse reaction to the drug which is potentially fatal. This report describes a patient with a history of successfully treated pyoderma gangrenosum, who developed agranulocytosis 3 we...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2009.02143.x

    authors: Yip G,Ekinci E,Lee ST,Jerums G,Grossmann M

    更新日期:2010-04-01 00:00:00

  • Sleep health New South Wales: chronic sleep restriction and daytime sleepiness.

    abstract:AIMS:The aim of this study was to provide the first population-based descriptions of typical sleep duration and the prevalence of chronic sleep restriction and chronic sleepiness in community-dwelling Australian adults. METHODS:Ten thousand subjects randomly selected from the New South Wales electoral roll, half aged ...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2007.01395.x

    authors: Bartlett DJ,Marshall NS,Williams A,Grunstein RR

    更新日期:2008-01-01 00:00:00

  • Analysis of multidisciplinary lung cancer practice.

    abstract:BACKGROUND:The aim of this study was to describe the activity of a lung cancer multidisciplinary clinic (MDC) and examine whether this model of clinical practice results in adherence to best-practice guidelines. METHODS:Prospective analysis of demographic and clinical data in 431 patients referred to a lung cancer MDC...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/j.1445-5994.2006.01237.x

    authors: Conron M,Phuah S,Steinfort D,Dabscheck E,Wright G,Hart D

    更新日期:2007-01-01 00:00:00

  • Reduction of in hospital Cardiac arrest rates in Intensive care equipped NSW hospitals in association with Implementation of Between the Flags Rapid Response System.

    abstract:BACKGROUND:The NSW Clinical Excellence commission introduced the "Between the Flags" program in response to the death of a young patient as a system wide approach for early detection and management of the deteriorating patient in all 242 NSW hospitals. The impact of BTF implementation on the 35 larger hospitals with IC...

    journal_title:Internal medicine journal

    pub_type: 杂志文章

    doi:10.1111/imj.14812

    authors: Bhonagiri D,Lander H,Green M,Straney L,Jones D,Pilcher D

    更新日期:2020-03-04 00:00:00

  • Treatment with unfunded drugs in oncology: the impact of access programmes and clinical trials.

    abstract:BACKGROUND:Where proven cancer therapies remain unfunded, patients are faced with difficult decisions regarding personally covering some or all of the treatment cost. Clinical trials provide an alternative form of access to unfunded drugs. AIMS:To examine the patient population and utilisation of the colorectal cancer...

    journal_title:Internal medicine journal

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-5994.2012.02750.x

    authors: Tie J,Gibbs P

    更新日期:2013-01-01 00:00:00