Cancer-associated prothrombotic pathways: leucocytosis, but not thrombocytosis, correlates with venous thromboembolism in women with ovarian cancer.

abstract：BACKGROUND:Iatrogenic medication errors are a cause of medical morbidity and mortality. They result in significant cost to the Australian healthcare system each year. There is limited Australian evidence describing the iatrogenic errors occurring within the hospital system. AIMS:To examine and describe iatrogenic medi...

journal_title：Internal medicine journal

authors： Bourke EM,Greene S,Macleod D,Robinson J

更新日期：2020-06-15 00:00:00

abstract：:Perhexiline is a prophylactic anti-anginal agent that ameliorates the metabolic basis for myocardial ischaemia and is increasingly used in the management of acute coronary syndromes. No intravenous preparation is available and usual oral loading regimens require 2-3 days to achieve therapeutic drug levels. Two patient...

journal_title：Internal medicine journal

authors： Philpott A,Chandy S,Morris R,Horowitz JD

更新日期：2004-06-01 00:00:00

abstract：AIMS:To evaluate the effectiveness of a new locality-based integrated diabetes care service for people with Type 2 diabetes in an inner regional area. METHODS:A quasi-experimental evaluation comparing baseline and follow up clinical data collected from general practices and specialist services participating in an inte...

journal_title：Internal medicine journal

authors： Zarora R,MacMillan F,Piya MK,Fernandes B,Simmons D

更新日期：2021-01-20 00:00:00

abstract：:This paper examines the differences between clinical and public health ethics and provides several examples of contemporary public health challenges that pose ethical questions. The relations among ethics, rights and obligations are explored, because public health philosophers propose these as different ways for publi...

journal_title：Internal medicine journal

authors： Leeder SR

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Infective endocarditis (IE) is a severe infection conferring significant morbidity and mortality. It is associated with geographical variation, complicating diagnosis and treatment of patients in a standardised manner. AIM:To evaluate the presentation, treatment and outcomes of patients with IE in the Hunte...

journal_title：Internal medicine journal

authors： Doig F,Loewenthal M,Lai K,Mejia R,Iyengar A

更新日期：2018-09-01 00:00:00

abstract：:Myocardial perfusion imaging is a relatively new technique in the emergency department management of acute chest pain. With improved sensitivity and specificity compared to traditional methods of risk stratification, an abnormal scan rapidly identifies individuals with acute perfusion abnormalities and allows the appr...

journal_title：Internal medicine journal

authors： Knott JC,Better N

更新日期：2001-12-01 00:00:00

abstract：:Vancomycin remains a clinically useful antibiotic despite the advent of several alternative drugs. Optimising vancomycin therapy with therapeutic drug monitoring is widely recommended. The aim of therapeutic drug monitoring is to help the clinician to achieve target pharmacodynamic parameters in the case of vancomycin...

journal_title：Internal medicine journal

authors： Avent ML,Vaska VL,Rogers BA,Cheng AC,van Hal SJ,Holmes NE,Howden BP,Paterson DL

更新日期：2013-02-01 00:00:00

abstract：:Clarithromycin is the most documented cytochrome P450 3A4 (CYP3A4) inhibitor to cause an adverse interaction with simvastatin. This particular case is of interest as rhabdomyolysis only occurred after an increase in the dose of clarithromycin. The patient developed raised cardiac biomarkers without any obvious cardiac...

journal_title：Internal medicine journal

authors： Page SR,Yee KC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Escalating morbidity and mortality associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infections represent a major health burden in Australia, particularly among migrants from endemic areas who may present late. METHODS AND AIMS:We evaluated the knowledge and educational needs of general pr...

journal_title：Internal medicine journal

authors： Guirgis M,Yan K,Bu YM,Zekry A

更新日期：2012-05-01 00:00:00

abstract：:Based on the number of new cases (incidence), non-Hodgkin lymphoma is an increasingly common cancer in Australia and many developed countries. Until recently, mortality trends have been stable or slightly increasing. However, since the year 2000, mortality has decreased every year by an average of 5.1% per year (95% c...

journal_title：Internal medicine journal

authors： Coory M,Gill D

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The risks are unknown for developing chronic gastrointestinal illness when personnel are relocated short term to other countries and when taking antibiotic prophylaxis in areas where malaria is endemic. AIM:To examine the associations of deployment to developed or developing countries and exposure to doxycy...

journal_title：Internal medicine journal

authors： Lee TW,Russell L,Deng M,Gibson PR

更新日期：2013-08-01 00:00:00

abstract：:Leprosy remains an important global health concern, but little has been published about its diagnosis and management in developed settings. It has been postulated that delay in diagnosis is common in developed settings. We reviewed all the cases of leprosy seen at a major tertiary referral centre between 1999 and 2013...

journal_title：Internal medicine journal

authors： Turner D,McGuinness SL,Leder K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Smartphones have become novel healthcare tools for patients with diabetes. However, it is uncertain whether the smartphone application support system helps in glycaemic control in patients with type 2 diabetes. AIMS:To evaluate the efficacy and plausibility of smartphone-based integrated online real-time di...

journal_title：Internal medicine journal

authors： Ku EJ,Park JI,Jeon HJ,Oh T,Choi HJ

更新日期：2020-12-01 00:00:00

abstract：:The burden and consequences of skin infections for remote living indigenous people are high. While skin infections are recognised as an antecedent to conditions such as acute rheumatic fever in children, data are limited concerning skin infection complications such as cellulitis, abscesses and osteomyelitis in older c...

journal_title：Internal medicine journal

authors： Thomas L,Bowen AC,Tong SYC

更新日期：2020-06-01 00:00:00

abstract：:A cross-sectional survey of 265 adult patients with haematological malignancy, haemoglobinopathy or human immunodeficiency virus was performed to determine the potential risk of infection from animal exposures. One hundred and thirty-seven (52%) owned an animal; the majority were dogs (74%) and cats (39%), but 14% own...

journal_title：Internal medicine journal

authors： Gurry GA,Campion V,Premawardena C,Woolley I,Shortt J,Bowden DK,Kaplan Z,Dendle C

更新日期：2017-03-01 00:00:00

abstract：:More than 177 000 potentially preventable healthcare-associated infections (HAIs) occur per annum in Australia with sizable attributable mortality. Organizational systems to protect against HAI in hospitals in Australia are relatively poorly developed. Awareness and practice of infection control by medical and other h...

journal_title：Internal medicine journal

authors： Ferguson JK

更新日期：2009-09-01 00:00:00

abstract：:A 75-year-old man of Fijian-Indian extraction complained of a 3-year history of progressive right knee pain and stiffness which were limiting his mobility. On examination, multiple hard nodules were palpable in the popliteal fossa and along the path of the quadriceps tendon. The joint line was not tender, knee flexion...

journal_title：Internal medicine journal

authors： Langguth DM,Klestov A,Denaro C

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limits quality of life. The CHA2 DS2 VASc score (congestive heart failure/left ventricular dysfunction, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular d...

journal_title：Internal medicine journal

authors： Mlodawska E,Tomaszuk-Kazberuk A,Lopatowska P,Kaminski M,Musial WJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The current results on the diagnostic accuracy of multidetector computed tomography (MDCT) in the detection of left atrial/left atrial appendage (LA/LAA) thrombus are conflicting. AIM:The aim of the present study was to determine the diagnostic accuracy of MDCT in LA/LAA thrombus with meta-ana...

journal_title：Internal medicine journal

authors： Ning Z,Min ZG,Jiang HX,Hu BL

更新日期：2013-05-01 00:00:00

abstract：:A 22-year-old woman presented with methanol toxicity manifesting as headache, reduced conscious state and visual change after consuming home-made grappa. She progressed to a coma with fixed mydriasis and severe acidaemia (pH 6.55). She was treated with empirical antidote administration (intravenous ethanol) and enhanc...

journal_title：Internal medicine journal

authors： Holt NR,Nickson CP

更新日期：2018-03-01 00:00:00

abstract：:The indication for permanent pacemaker remains controversial in malignant neurocardiogenic syncope. A highly reproducible prolonged pause during a repeat head-up tilt-table testing may identify a subgroup of neurally mediated syncope with a prominent and consistent cardioinhibitory component. Seven patients (3 females...

journal_title：Internal medicine journal

authors： Omar AR,Ng KS,Ng WL,Sutandar A

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The thiopurines azathioprine and 6-mercaptopurine are recommended for maintenance of remission in inflammatory bowel disease (IBD). Measurement of concentrations of the metabolites 6-thioguanine nucleotide and 6-methylmercaptopurine helps delineate interindividual variation in metabolism that may underlie va...

journal_title：Internal medicine journal

authors： Kennedy NA,Asser TL,Mountifield RE,Doogue MP,Andrews JM,Bampton PA

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Tobacco cessation after acute myocardial infarction (AMI) substantially improves outcome but how effective individual programmes are needs to be established. To date, few studies have examined this factor. AIMS:To assess the outcome of two smoking cessation programmes after AMI. METHODS:One hundred and nin...

journal_title：Internal medicine journal

authors： Feeney GF,McPherson A,Connor JP,McAlister A,Young MR,Garrahy P

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) accuracy after neoadjuvant systemic therapy (NST) for breast cancer varies according to hormone receptor (HR), human epidermal growth factor receptor type-2 (HER2) subtype and Ki-67 proliferation index. Whether MRI accuracy varies by genomic signatures is unknown. We examined...

journal_title：Internal medicine journal

authors： Murphy C,Mukaro V,Tobler R,Asher R,Gibbs E,West L,Giuffre B,Baron-Hay S,Khasraw M

更新日期：2018-06-01 00:00:00

abstract：:An acute pulmonary embolism (aPE) is characterised by occlusion of one or more pulmonary arteries. Physiological disturbance may be minimal, but often cardiac output decreases as the right ventricle attempts to overcome increased afterload. Additionally, ventilation-perfusion mismatches can develop in affected vascula...

journal_title：Internal medicine journal

authors： Hepburn-Brown M,Darvall J,Hammerschlag G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The cost of diabetes is high for both the individual and society. Future health-care planning requires patient-level diabetes-attributable health-care cost data that have not previously been available for Australia. AIM:To determine Australian national direct diabetes-attributable health-care costs for know...

journal_title：Internal medicine journal

authors： Davis WA,Knuiman MW,Hendrie D,Davis TM

更新日期：2006-03-01 00:00:00

abstract：:To share our experience of establishing an acute outreach service to nursing homes and to evaluate the impact of such service on emergency department presentations, data were drawn from a pre-existing database from 2013 to 2017. Of the 986 acute patients treated in 12 nursing homes over a 23-month period, the acute ge...

journal_title：Internal medicine journal

authors： Chan DKY,Liu FX,Irwanto D,Prasetyo D,Ozorio G,Li F,Smith M,Sharma A,Chen J

更新日期：2018-11-01 00:00:00

abstract：:The phenomenon of addiction is complex, although its expression clinically is relatively straightforward. There is a series of neurophysiological changes that mediate changes in the mesolimbic and mesocortical systems which in turn lead to disturbances in reward mechanisms. These then act to perpetuate the cycle of in...

journal_title：Internal medicine journal

authors： Foy A

更新日期：2007-05-01 00:00:00

abstract：:Diabetes can lead to a myriad of microvascular and macrovascular complications - with the leading cause of mortality in diabetes being cardiovascular disease. Low-density lipoprotein cholesterol, along with non-high-density lipoprotein cholesterol and triglycerides are proven, modifiable risk factors for cardiovascula...

journal_title：Internal medicine journal

authors： Cheung YM,O'Brien R,Ekinci EI

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:In an era of growing subspecialisation there has been significant research into the role, determinants and outcomes of outpatient referrals but very little on inpatient specialty referrals from general medical units. AIMS:This study aims to describe and compare the rate of specialty referrals from inpatient...

journal_title：Internal medicine journal

authors： Brown MG,Campbell D,Maydom BW

更新日期：2014-09-01 00:00:00