Severe methanol poisoning with neurological sequelae: implications for diagnosis and management.

Abstract:

:A 22-year-old woman presented with methanol toxicity manifesting as headache, reduced conscious state and visual change after consuming home-made grappa. She progressed to a coma with fixed mydriasis and severe acidaemia (pH 6.55). She was treated with empirical antidote administration (intravenous ethanol) and enhanced elimination through haemodialysis. She survived despite her delayed presentation but developed significant neurological sequelae, including visual impairment. We provide an overview of key elements of diagnosis and recent updates in treatment recommendations.

journal_name

Intern Med J

authors

Holt NR,Nickson CP

doi

10.1111/imj.13725

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

335-339

issue

3

eissn

1444-0903

issn

1445-5994

journal_volume

48

pub_type

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