Ironic case of hepatic dysfunction following the global withdrawal of sitaxentan.

abstract：:Based on the number of new cases (incidence), non-Hodgkin lymphoma is an increasingly common cancer in Australia and many developed countries. Until recently, mortality trends have been stable or slightly increasing. However, since the year 2000, mortality has decreased every year by an average of 5.1% per year (95% c...

journal_title：Internal medicine journal

authors： Coory M,Gill D

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Timor-Leste is one of the poorest countries in the world. The East Timor Hearts Fund is a charitable organisation involving Australian cardiologists providing outreach screening and access to cardiac interventions. AIMS:To assess ten years of clinical volume, demographics and patient outcomes. Our intention...

journal_title：Internal medicine journal

authors： Paratz ED,Mock N,Gutman SJ,Horton A,Creati L,Appelbe A,Eggleton S,Kushwaha V,da Silva Almeida IT,Monteiro A,Bayley N

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Glomerular M-type phospholipase A2 receptor (PLA2 R) is important for diagnosing idiopathic membranous nephropathy (IMN). The relation between glomerular PLA2 R expression and response to treatment remains to be explored. AIMS:We conducted the study to explore the positive rate and clinical significance of ...

journal_title：Internal medicine journal

authors： Liu H,Luo W,Gong S,Ding X

更新日期：2016-11-01 00:00:00

abstract：:Waldenström macroglobulinaemia (WM) is an indolent B-cell malignancy characterised by the presence of immunoglobulin M (IgM) paraprotein and bone marrow infiltration by clonal small B lymphocytes, plasmacytoid lymphocytes and plasma cells. The symptoms of WM are protean, often follow an asymptomatic phase and may incl...

journal_title：Internal medicine journal

authors： Talaulikar D,Tam CS,Joshua D,Ho JP,Szer J,Quach H,Spencer A,Harrison S,Mollee P,Roberts AW,Horvath N,Lee C,Zannettino A,Brown R,Augustson B,Jaksic W,Gibson J,Kalff A,Johnston A,Trotman J,Kalro A,Grigoriadis G,

更新日期：2017-01-01 00:00:00

abstract：:Healthcare encompasses multiple discourses to which health professionals, researchers, patients, carers and lay individuals contribute. Networks of patients and non-professionals often act collectively to build capacity, enhance access to resources, develop understanding and improve provision of care. This article exp...

journal_title：Internal medicine journal

authors： Grant MP,Philip JAM,Deliens L,Komesaroff PA

更新日期：2019-09-01 00:00:00

abstract：AIM:To ascertain the prevalence of HER2/neu-positive early breast cancer (EBC), utilisation of adjuvant trastuzumab and incidence of cardiac toxicity in a community private hospital setting. METHODS:Prospective data collected by breast oncologist and surgeons in all women diagnosed with EBC at the Mount Hospital (MH) ...

journal_title：Internal medicine journal

authors： Chan A,McGregor SR

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The effects of empagliflozin on cardiac structure and function are not known. AIMS:To examine the changes in cardiac structure and function following the addition of empagliflozin in patients with type 2 (T2D) diabetes using cardiac magnetic resonance (CMR) imaging. METHODS:Twenty patients attending a spec...

journal_title：Internal medicine journal

authors： Cohen ND,Gutman SJ,Briganti EM,Taylor AJ

更新日期：2019-08-01 00:00:00

abstract：:Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are an increasingly prescribed class of medication for type 2 diabetes mellitus. Euglycaemic diabetic ketoacidosis (euDKA) has been reported in association with SGLT2i use. Clinicians need to understand how to recognise and treat this complication. We describe three ...

journal_title：Internal medicine journal

authors： Isaacs M,Tonks KT,Greenfield JR

更新日期：2017-06-01 00:00:00

abstract：:Cardiac involvement is not regarded as a feature of Henoch-Schönlein purpura (HSP). We report a patient with HSP who developed significant cardiac symptoms, which resolved with immunosuppression. We review previous cases of HSP with cardiac features, none of which showed a response to treatment, and discuss evidence t...

journal_title：Internal medicine journal

authors： Polizzotto MN,Gibbs SD,Beswick W,Seymour JF

更新日期：2006-05-01 00:00:00

abstract：:We report the first published case of aggressive diffuse large B-cell (non-Hodgkin) lymphoma in a 35-year-old pregnant woman who had Crohn disease and was taking long-term thiopurine therapy: the patient developed placental insufficiency, and there was intrauterine fetal death. ...

journal_title：Internal medicine journal

authors： Chen G,Crispin P,Cherian M,Dahlstrom JE,Sethna FF,Kaye G,Pavli P,Subramaniam K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:There is a high risk of developing venous thromboembolism (VTE) following total knee arthroplasty (TKA). Conventional thromboprophylactic agents have limitations, such as route of administration, the need for monitoring, narrow therapeutic windows and interactions. Apixaban is a new oral anticoagulant with t...

journal_title：Internal medicine journal

authors： King DA,Pow RE,Dickison DM,Vale PR

更新日期：2016-09-01 00:00:00

abstract：:In Australia, mutations in epidermal growth factor mutations (EGFR) occur in 15% of patients diagnosed with non-small-cell lung cancer and are found with higher frequency in female, non-smokers of Asian ethnicity. Activating mutations in the EGFR gene are rarely described in SCLC. We present two cases of de novo EGFR ...

journal_title：Internal medicine journal

authors： Thai A,Chia PL,Russell PA,Do H,Dobrovic A,Mitchell P,John T

更新日期：2017-09-01 00:00:00

abstract：:The author, a physician in late middle age reflects on his own medical career, the aging of those who have taught him and also of those whom he has taught. He describes the sense of ennui and déjà vu. The things that seemed important as a younger doctor seem less important. He has adopted a different paradigm and has ...

journal_title：Internal medicine journal

authors： Allen RK

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The association between weather and severe acute respiratory syndrome (SARS) transmission in Beijing and Hong Kong in the 2003 epidemic was studied to examine the effect of weather on SARS transmission. METHODS:Pearson's correlation analyses and negative binomial regression analyses were used to quantify th...

journal_title：Internal medicine journal

authors： Bi P,Wang J,Hiller JE

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is a newly recognised condition that is apparently increasing in prevalence, and the aetiology is poorly understood. The role of aeroallergens in EoE is controversial, given the success of dietary therapy. Massive aeroallergen exposure leading to food bolus obstruction events (...

journal_title：Internal medicine journal

authors： Philpott HL,Nandurkar S,Thien F,Bloom S,Lin E,Goldberg R,Boyapati R,Finch A,Royce SG,Gibson PR

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Anticipating the prospect of specific treatment, we studied a large group of Australians with Fabry's disease. AIMS:We aimed to: (i) document the clinical features of Fabry's disease in Australian patients, (ii) test the hypothesis that clinical features vary with specific mutation and blood group and (iii)...

journal_title：Internal medicine journal

authors： Galanos J,Nicholls K,Grigg L,Kiers L,Crawford A,Becker G

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limits quality of life. The CHA2 DS2 VASc score (congestive heart failure/left ventricular dysfunction, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular d...

journal_title：Internal medicine journal

authors： Mlodawska E,Tomaszuk-Kazberuk A,Lopatowska P,Kaminski M,Musial WJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Management of acute ischaemic stroke is time critical. Reducing time to treatment with thrombolysis is strongly associated with improved outcomes in properly selected patients. However, there are barriers to ensuring timely treatment in the hospital setting. AIM:To determine if simple, no-cost protocol chan...

journal_title：Internal medicine journal

authors： Silsby M,Duma SR,Fois AF,Yin YWK,Koryzna J,Mahant N,Evans A,Fung VSC

更新日期：2019-11-01 00:00:00

abstract：:The move by the Medical Board of Australia to commence a conversation with the medical profession about revalidation reflects that patient-centred care is at the heart of good medical practice. Patients judge their doctors' commitment to them based on whether their individual interactions with doctors meet their needs...

journal_title：Internal medicine journal

authors： Phelps G,Dalton S

更新日期：2013-11-01 00:00:00

abstract：:The differential diagnosis of Parkinsonian syndromes is challenging, especially in the elderly as they often have complex presentations. Nuclear imaging modalities can increase diagnostic accuracy. Single-photon emission tomography (SPECT) using the ligand (99m Tc)-TRODAT-1 is used overseas but is yet to be approved i...

journal_title：Internal medicine journal

authors： Wong D,Veitch P,Schembri G

更新日期：2018-09-01 00:00:00

abstract：:This review summarises the available clinical trials data investigating the effects of glucose lowering on mortality in patients admitted to hospital with acute myocardial infarction. The results of these studies are inconclusive with no clear evidence that this intervention has additional benefit over and above routi...

journal_title：Internal medicine journal

authors： Braatvedt GD

更新日期：2008-05-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Polyserositis (PS) is the inflammation, with effusion, of different serous membranes. It has been associated with different aetiologies, but the aetiology of PS remains unknown in a high percentage of patients. AIMS:The general objective of this retrospective study was to analyse the aetiology of PS cases s...

journal_title：Internal medicine journal

authors： Losada I,González-Moreno J,Roda N,Ventayol L,Borjas Y,Domínguez FJ,Fernández-Baca V,García-Gasalla M,Payeras A

更新日期：2018-08-01 00:00:00

abstract：:Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...

journal_title：Internal medicine journal

authors： Chen BS,Wong SHC,Hawkins S,Huggins L

更新日期：2018-12-01 00:00:00

abstract：:A 22-year-old woman presented with methanol toxicity manifesting as headache, reduced conscious state and visual change after consuming home-made grappa. She progressed to a coma with fixed mydriasis and severe acidaemia (pH 6.55). She was treated with empirical antidote administration (intravenous ethanol) and enhanc...

journal_title：Internal medicine journal

authors： Holt NR,Nickson CP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHOD...

journal_title：Internal medicine journal

authors： Thomas MG,Morris AJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Iatrogenic medication errors are a cause of medical morbidity and mortality. They result in significant cost to the Australian healthcare system each year. There is limited Australian evidence describing the iatrogenic errors occurring within the hospital system. AIMS:To examine and describe iatrogenic medi...

journal_title：Internal medicine journal

authors： Bourke EM,Greene S,Macleod D,Robinson J

更新日期：2020-06-15 00:00:00

abstract：BACKGROUND:The reported risk of depression in patients with hypomagnesaemia is controversial. AIM:The objective of this meta-analysis was to assess the association between depression and hypomagnesaemia. METHODS:A literature search was performed using MEDLINE, EMBASE, Cochrane Database and clinicaltrials.gov from inc...

journal_title：Internal medicine journal

authors： Cheungpasitporn W,Thongprayoon C,Mao MA,Srivali N,Ungprasert P,Varothai N,Sanguankeo A,Kittanamongkolchai W,Erickson SB

更新日期：2015-04-01 00:00:00

abstract：:An 11-year-old boy presented with hepatic failure secondary to parvovirus B19 infection, requiring urgent liver transplantation. His recovery was complicated by primary Epstein-Barr virus and cytomegalovirus infections. He subsequently developed aplastic anaemia that has been refractory to antithymocyte globulin and c...

journal_title：Internal medicine journal

authors： So K,Macquillan G,Garas G,Delriviere L,Mitchell A,Speers D,Mews C,Augustson B,de Boer WB,Baker D,Jeffrey GP

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Tuberculous lymphadenitis is the commonest form of extrapulmonary tuberculosis. However, the optimal approach to diagnosis, employing biopsy by either fine needle aspiration (FNA) or surgical excision, remains uncertain. AIMS:To evaluate the diagnostic value of biopsy using each of the component diagnostic ...

journal_title：Internal medicine journal

authors： Knox J,Lane G,Wong JS,Trevan PG,Karunajeewa H

更新日期：2012-09-01 00:00:00