Prevalence and management of HER2/neu-positive early breast cancer in a single institution following availability of adjuvant trastuzumab.

abstract：:Influenza vaccination is an important preventative health measure. A significant proportion of general medical inpatients meets indications for annual inactivated influenza vaccination (IIV), as recommended by the Australian National Immunisation Programme. This study explores opportunities to provide IIV to eligible ...

journal_title：Internal medicine journal

authors： Zaman FY,Nagalingam V,Wong C,Khu YL,Teng HWG,Janardan J,Ritchie E,Cheng AC,Aung AK

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:There is no valid cardiovascular disease (CVD) risk prediction equation for Australians with diabetes. The aim of this study is to develop and validate a multivariate risk function for 5-year cardiovascular risk prediction in Australian type 2 diabetes patients. METHODS:The Fremantle Diabetes Study is a com...

journal_title：Internal medicine journal

authors： Davis WA,Knuiman MW,Davis TM

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The altered status of iron metabolism is reported in hereditary haemochromatosis and in non-alcoholic liver fatty disease. We investigated the relation between the H63D HFE mutation gene and non-alcoholic steatohepatitis (NASH). METHODS:We studied as outpatients, 272 Italian persons with NASH and compared t...

journal_title：Internal medicine journal

authors： Neri S,Pulvirenti D,Signorelli S,Ignaccolo L,Tsami A,Mauceri B,Misseri M,Interlandi D,Cutuli N,Castellino P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Acute poisoning accounts for a significant proportion of the total burden of disease worldwide. While the rate of poisoning fatalities in New Zealand is comparable to other industrialised countries, demographic trends in incidence, particularly including socio-economic indicators and substances involved, are...

journal_title：Internal medicine journal

authors： Peiris-John R,Kool B,Ameratunga S

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND/AIM:In patients discharged from an Older Person's Health hospital, we assessed (i) the prevalence of anticholinergic medications (ACM) in this study population and (ii) changes in anticholinergic drug burden during admission using the Anticholinergic Drug Scale (ADS). METHODS:Cases were identified between S...

journal_title：Internal medicine journal

authors： Lee MSS,Hanger HC

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Glomerular M-type phospholipase A2 receptor (PLA2 R) is important for diagnosing idiopathic membranous nephropathy (IMN). The relation between glomerular PLA2 R expression and response to treatment remains to be explored. AIMS:We conducted the study to explore the positive rate and clinical significance of ...

journal_title：Internal medicine journal

authors： Liu H,Luo W,Gong S,Ding X

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Trends in the incidence of acute myocardial infarction (AMI) provide important information for healthcare providers and can allow for accurate planning of future health needs and targeted interventions in areas with an excess burden of cardiovascular disease. AIM:To investigate the regional variations in AM...

journal_title：Internal medicine journal

authors： Davies AJ,Naudin C,Al-Omary M,Khan A,Oldmeadow C,Jones M,Bastian B,Bhagwandeen R,Fletcher P,Leitch J,Boyle A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The role of brentuximab peri-allogeneic transplantation in patients with relapsed and/or refractory CD30 positive lymphomas remains poorly defined. AIM:To assess the outcome of use of brentuximab as a bridge to allogeneic stem cell transplantation (SCT) in patient with relapsed/refractory CD30+ classic Hodg...

journal_title：Internal medicine journal

authors： Mediwake H,Morris K,Curley C,Butler J,Kennedy G

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The relationship between serum triglycerides (TG) level and the risk of coronary heart disease (CHD) mortality remains controversial. AIMS:To evaluate whether TG level is a risk factor for CHD in elderly people from general population, and to look for interactions between TG and other risk factors. METHODS...

journal_title：Internal medicine journal

authors： Mazza A,Tikhonoff V,Schiavon L,Casiglia E

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:A Resuscitation Plan is a medically authorised order to use or withhold resuscitation interventions. Absence of appropriate resuscitation orders exposes patients to the risk of invasive medical interventions that may be of questionable benefit depending on individual circumstances. AIMS:To describe among ju...

journal_title：Internal medicine journal

authors： Bryant J,Waller A,Pickles R,Hullick C,Price E,White B,Willmott L,Bowman MA,Knight A,Ryall MA,Sanson-Fisher R

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Advance care planning (ACP) provides patients with the ability to make their decisions known about how they would like to be treated if they lose capacity. Medical practitioners have a key role to play in providing information on ACP to their patients. This research explores their knowledge and attitudes to ...

journal_title：Internal medicine journal

authors： Cartwright C,Montgomery J,Rhee J,Zwar N,Banbury A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Informed consent is a mainstay of clinical practice, with both moral and legal forces. Material disclosure about extreme treatments, however, is unlikely to convey the full impact of the experience of treatment. Informed consent may be flawed under such circumstances. The aims of this study were to compare e...

journal_title：Internal medicine journal

authors： Little M,Jordens CF,McGrath C,Montgomery K,Lipworth W,Kerridge I

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Neutropenic fever is a frequently encountered complication when caring for cancer patients and can lead to intensive care admission, with high mortality rates in those patients who require invasive mechanical ventilation (IMV). Although hospital survival in this population has improved, long-term outcomes of...

journal_title：Internal medicine journal

authors： Mackintosh D,Way M,Reade MC,Dhanani J

更新日期：2020-05-01 00:00:00

abstract：:A cross-sectional survey of 265 adult patients with haematological malignancy, haemoglobinopathy or human immunodeficiency virus was performed to determine the potential risk of infection from animal exposures. One hundred and thirty-seven (52%) owned an animal; the majority were dogs (74%) and cats (39%), but 14% own...

journal_title：Internal medicine journal

authors： Gurry GA,Campion V,Premawardena C,Woolley I,Shortt J,Bowden DK,Kaplan Z,Dendle C

更新日期：2017-03-01 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Anticoagulants are recommended to prevent cardioembolic stroke in most patients with atrial fibrillation (AF). Management errors with anticoagulation and use of aspirin instead of anticoagulants have been documented worldwide, especially with vitamin K antagonists. We assessed the rate of anticoagul...

journal_title：Internal medicine journal

authors： Wong E,Aaqib M,Thijs V

更新日期：2020-12-21 00:00:00

abstract：BACKGROUND:  Alcoholic liver disease (ALD) is an important contributor to the total burden of alcohol-related harm; however, the morbidity of different types of ALD in Australia has not been described. The aim of this study was to investigate recent trends in hospital admission rates among alcoholic liver cirrhosis, al...

journal_title：Internal medicine journal

authors： Liang W,Chikritzhs T,Pascal R,Binns CW

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:While treatment guidelines have been developed to guide the management of Staphylococcus aureus bacteraemia, there is a need to validate these guidelines in different clinical settings and to relate the effect of compliance to clinical outcome. AIMS:To assess the impact of adherence to treatment guidelines ...

journal_title：Internal medicine journal

authors： Blyth CC,Darragh H,Whelan A,O'Shea JP,Beaman MH,McCarthy JS

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Peptic ulcer disease risk factors have changed, as has the impact of treatment on morbidity and mortality. Recent data on clinical presentation and outcome are sparse in Australia. AIM:To determine the characteristics and outcome of patients presenting with a bleeding peptic ulcer to a tertiary referral cen...

journal_title：Internal medicine journal

authors： Halland M,Young M,Fitzgerald MN,Inder K,Duggan JM,Duggan A

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome occurs in one to six per 1000 pregnancies; maternal death has been reported in 1-24% of cases. Vague presentation is common; hypertension and proteinuria which characterise pre eclampsia are often absent when HELLP syndrome presents. Physi...

journal_title：Internal medicine journal

authors： Jayawardena L,Mcnamara E

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Plasma homocysteine is elevated in patients with end-stage renal disease (ESRD) and is a risk factor for cardiovascular disease. Folic acid has been shown to partially reduce homocysteine levels in dialysis patients. It is not known whether vitamin B12 reduces homocysteine independent of folic acid in patien...

journal_title：Internal medicine journal

authors： Polkinghorne KR,Zoungas S,Branley P,Villanueva E,McNeil JJ,Atkins RC,McGrath BP,Kerr PG

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:An adequately powered, double-blind, multisite, randomised controlled trial has shown no net clinical benefit for subcutaneous ketamine over placebo in the management of cancer pain refractory to combination opioid and co-analgesic therapy. The results of the trial were disseminated widely both nationally an...

journal_title：Internal medicine journal

authors： Hardy JR,Spruyt O,Quinn SJ,Devilee LR,Currow DC

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:  Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...

journal_title：Internal medicine journal

authors： Keogh A,Strange G,Kotlyar E,Williams T,Kilpatrick D,Macdonald P,Brown K,Pidoux A,Kermeen F,Steele P,Dalton B,Gabbay E

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Stroke neurologists, vascular surgeons, interventional neuroradiologists and interventional cardiologists have embraced carotid angioplasty and stenting (CAS) because of potential advantages over carotid endarterectomy (CEA). At Austin Health, a multidisciplinary neuro-interventional group was formed to stan...

journal_title：Internal medicine journal

authors： Mak CS,Chambers BR,Clark DJ,Molan M,Brooks M,Roberts N,Fell G,Roberts AK,New G,Donnan GA

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Asthma is associated with fixed airflow obstruction and an increased risk of death. The aim of this study was to relate asthma mortality and airflow obstruction to severity of asthma in a cohort of patients with chronic asthma studied over a 17-year period. METHODS:In 1980, asthma severity based on symptoms...

journal_title：Internal medicine journal

authors： Panizza JA,James AL,Ryan G,de Klerk N,Finucane KE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Poor sleep is common after stroke, and data regarding its effect on rehabilitation outcomes are limited. Controversial evidence was found concerning the effect of sedatives on improving sleep quality in poor sleepers after stroke. AIM:To assess the prevalence of poor sleep in post-stroke patients and its ef...

journal_title：Internal medicine journal

authors： Iddagoda MT,Inderjeeth CA,Chan K,Raymond WD

更新日期：2020-02-01 00:00:00

abstract：:Perhexiline is a prophylactic anti-anginal agent that ameliorates the metabolic basis for myocardial ischaemia and is increasingly used in the management of acute coronary syndromes. No intravenous preparation is available and usual oral loading regimens require 2-3 days to achieve therapeutic drug levels. Two patient...

journal_title：Internal medicine journal

authors： Philpott A,Chandy S,Morris R,Horowitz JD

更新日期：2004-06-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) is a potentially fatal complication in solid organ and bone marrow transplant patients, with reported incidence of 0.5-3% and mortality of about 75%. To emphasise the importance of early diagnosis and prompt commencement of therapy results in improved clinical outcomes. A retrospective...

journal_title：Internal medicine journal

authors： Nwaba A,MacQuillan G,Adams LA,Garas G,Delriviere L,Augustson B,DeBoer B,Moody H,Jeffrey GP

更新日期：2013-03-01 00:00:00