Abstract:
:The author, a physician in late middle age reflects on his own medical career, the aging of those who have taught him and also of those whom he has taught. He describes the sense of ennui and déjà vu. The things that seemed important as a younger doctor seem less important. He has adopted a different paradigm and has come to see that both playfulness and integrity are essential ingredients for health. As a sailor, he more keenly appreciates the struggles our patients and colleagues have with illness and draws an analog between sailing and life.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Allen RKdoi
10.1111/j.1445-5994.2006.01256.xsubject
Has Abstractpub_date
2006-12-01 00:00:00pages
800-2issue
12eissn
1444-0903issn
1445-5994pii
IMJ1256journal_volume
36pub_type
杂志文章abstract::ABSTRACT Treatment of invasive fungal infections is increasingly complex. Amphotericin B deoxycholate has long been the mainstay of treatment. However, there has been increasing recognition of both the propensity for nephro-toxicity in haematology, transplant and intensive care patients as well as its adverse impact o...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1444-0903.2004.00541.x
更新日期:2004-04-01 00:00:00
abstract::This pilot study in a prospective cohort of 20 cryptogenic stroke patients showed that a significant proportion has paroxysmal atrial fibrillation undetected by 24-h Holter monitoring. However, longer monitoring with 28-day Holter was poorly tolerated and still insufficiently sensitive for paroxysmal atrial fibrillati...
journal_title:Internal medicine journal
pub_type: 临床试验,杂志文章
doi:10.1111/imj.12410
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Peptic ulcer disease risk factors have changed, as has the impact of treatment on morbidity and mortality. Recent data on clinical presentation and outcome are sparse in Australia. AIM:To determine the characteristics and outcome of patients presenting with a bleeding peptic ulcer to a tertiary referral cen...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02357.x
更新日期:2011-08-01 00:00:00
abstract::As life expectancy for people living with human immunodeficiency virus (HIV) (PLWHIV) increases, management models for HIV infection are changing. To understand approaches to practice within this shifting climate and across different medical settings, in 2017 we conducted a baseline survey among the main medical pract...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.15129
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Cardiac myxoma is a rare but important cause of stroke, which affects young people. More recently the diagnosis has been enhanced by the use of echocardiograms. We aimed to review the neurological presentations, including stroke, of cardiac myxoma in this modern era of diagnosis and management. MET...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1444-0903.2004.00563.x
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:There is no mechanism in place for monitoring or quality improvement of cancer multidisciplinary meetings (MDM) in Australia. AIM:To develop a peer-review process for quality improvement of MDM. METHODS:This project involved three phases: (i) development of a draft peer-review framework, supporting documen...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.13374
更新日期:2017-05-01 00:00:00
abstract::Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2008.01632.x
更新日期:2008-04-01 00:00:00
abstract::Environmental exposures in the foetal period may predispose to autoimmunity. Aim of this study is to investigate whether seasonality in birth patterns exists in idiopathic inflammatory myopathies (IIM). We used Stata (StataCorp USA, version 13.0) and the user-written routine command 'circsummarise' to assess birth sea...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13061
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Since 1995 patients with relapsed aggressive non-Hodgkin lymphoma have been treated with high-dose chemotherapy (HDC) instead of standard dose chemotherapy (SC) because of superior survival shown in the 'Parma study'. As HDC involves hospital admission and intensive supportive care, the cost of HDC would be ...
journal_title:Internal medicine journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1445-5994.2008.01795.x
更新日期:2009-08-01 00:00:00
abstract::Paradigms for managing acromegaly have undergone major changes in the past two decades. This has been brought about by combining surgical, pharmacological and radiotherapeutic approaches that provide tight biochemical control to reduce mortality to that of the general population. The biochemical targets for treatment ...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2006.01097.x
更新日期:2006-07-01 00:00:00
abstract::Myocardial perfusion imaging is a relatively new technique in the emergency department management of acute chest pain. With improved sensitivity and specificity compared to traditional methods of risk stratification, an abnormal scan rapidly identifies individuals with acute perfusion abnormalities and allows the appr...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1046/j.1445-5994.2001.00118.x
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Numerous studies have shown differences in pain perception between men and women, which may affect pain management strategies. AIM:Our primary aim was to investigate whether there are gender-based differences in pain management in patients admitted to our emergency department with acute, non-specific abdomi...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02255.x
更新日期:2012-03-01 00:00:00
abstract:AIM:To determine diagnostic rate, complications and patient tolerability of endobronchial ultrasound-guide sheath (EBUS-GS) and computed tomography (CT)-guided percutaneous core biopsy for peripheral lung lesions. METHODS:Lesions >1 cm diameter on CT were randomised to either EBUS-GS or CT-guided biopsy. Excluded were...
journal_title:Internal medicine journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1445-5994.2011.02707.x
更新日期:2012-08-01 00:00:00
abstract::Doctor-patient language discordance has been shown to lead to worse clinical outcomes. In this study of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction at an Australian health service, we demonstrated that limited English proficiency (LEP) is an independent predict...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13751
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Eosinophilic esophagitis (EoE) is a newly recognised condition that is apparently increasing in prevalence, and the aetiology is poorly understood. The role of aeroallergens in EoE is controversial, given the success of dietary therapy. Massive aeroallergen exposure leading to food bolus obstruction events (...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/imj.12790
更新日期:2015-09-01 00:00:00
abstract::We hereby present two case reports of moderate coronavirus disease patients, suffering from profound hypoxaemia, further deteriorating later on. A schedule pre-planned awake prone position manoeuvres were executed during their hospital stay. Following this, the patients' saturation improved, later to be weaned from ox...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14926
更新日期:2020-08-01 00:00:00
abstract::Based on the number of new cases (incidence), non-Hodgkin lymphoma is an increasingly common cancer in Australia and many developed countries. Until recently, mortality trends have been stable or slightly increasing. However, since the year 2000, mortality has decreased every year by an average of 5.1% per year (95% c...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2008.01809.x
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:High concentration oxygen is commonly administered during acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of this study was to determine the association between oxygen, severity markers and poor outcomes in AECOPD. METHODS:In an audit of patients with AECOPD arriving by ambula...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02207.x
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:In 2003, chronic obstructive pulmonary disease (COPD) accounted for 46% of the burden of chronic respiratory disease in the Australian community. In the 65-74-year-old age group, COPD was the sixth leading cause of disability for men and the seventh for women. AIMS:To measure the influence of disease severi...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02195.x
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Poor quality prescribing has been identified as one of the leading causes of medication error and adverse drug events. The aim of this study was to improve the quality of written prescriptions in a general hospital by a combination of serial audits and interventions designed to address identified deficiencie...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01518.x
更新日期:2008-04-01 00:00:00
abstract:AIM:To develop a well-tolerated outpatient chemotherapy regimen for hormone-insensitive prostate cancer. METHOD:Forty patients received carboplatin 20 mg/m2 by continuous ambulatory infusion with oral etoposide 50 mg/day for 21 days repeated every 6 weeks. RESULTS:Four patients had a partial response and 16 patients ...
journal_title:Internal medicine journal
pub_type: 临床试验,杂志文章
doi:10.1111/j.1445-5994.2005.00864.x
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND/AIM:Although induction chemotherapy comprising high-dose cytarabine (HiDAC) in combination with idarubicin and etoposide or 'ICE' for adult acute myeloid leukaemia (AML) produces a complete remission rate of nearly 80%, gastrointestinal toxicity is significant. Omission of etoposide may produce similar clini...
journal_title:Internal medicine journal
pub_type: 临床试验,杂志文章,评审
doi:10.1111/j.1445-5994.2012.02868.x
更新日期:2013-03-01 00:00:00
abstract::Significant developments have occurred in the discipline of palliative care in the modern era. This paper shall explore those developments, challenge some widely held misconceptions about the role and daily practice of the discipline, highlight the growing recognition of the role of palliative care in non-malignant di...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13520
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Myelodysplastic syndrome (MDS), a haematological disorder of the elderly, has been formally classified as a neoplastic disease for 10 years. AIMS:Our aim was to collate national cancer registry incidence data to describe the epidemiology of MDS in New Zealand. METHODS:The New Zealand Cancer Registry has no...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2011.02619.x
更新日期:2012-11-01 00:00:00
abstract::Thrombotic microangiopathy (TMA) is a potentially fatal complication in solid organ and bone marrow transplant patients, with reported incidence of 0.5-3% and mortality of about 75%. To emphasise the importance of early diagnosis and prompt commencement of therapy results in improved clinical outcomes. A retrospective...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12048
更新日期:2013-03-01 00:00:00
abstract::An 11-year-old boy presented with hepatic failure secondary to parvovirus B19 infection, requiring urgent liver transplantation. His recovery was complicated by primary Epstein-Barr virus and cytomegalovirus infections. He subsequently developed aplastic anaemia that has been refractory to antithymocyte globulin and c...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01293.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Stroke neurologists, vascular surgeons, interventional neuroradiologists and interventional cardiologists have embraced carotid angioplasty and stenting (CAS) because of potential advantages over carotid endarterectomy (CEA). At Austin Health, a multidisciplinary neuro-interventional group was formed to stan...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02285.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF), an important and treatable cause of ischaemic stroke, can occur as a sustained or a paroxysmal arrhythmia. Continuous cardiac rhythm monitoring (Holter monitoring) is often performed in stroke patients to identify paroxysmal AF, which is an indication for warfarin anti-coagulation i...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1444-0903.2004.00589.x
更新日期:2004-06-01 00:00:00
abstract::The Queensland branch of the Royal Australasian College of Physicians (RACP) commissioned this study to update their workforce profile and examine rural practice. The present investigation aimed to describe characteristics of Queensland physicians and determine the influence of childhood and training locations on curr...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13156
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The cost of diabetes is high for both the individual and society. Future health-care planning requires patient-level diabetes-attributable health-care cost data that have not previously been available for Australia. AIM:To determine Australian national direct diabetes-attributable health-care costs for know...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01014.x
更新日期:2006-03-01 00:00:00