Abstract:
BACKGROUND:Myelodysplastic syndrome (MDS), a haematological disorder of the elderly, has been formally classified as a neoplastic disease for 10 years. AIMS:Our aim was to collate national cancer registry incidence data to describe the epidemiology of MDS in New Zealand. METHODS:The New Zealand Cancer Registry has now reported five complete years of incidence data, the last three of which were used for analysis. For the years 2005-2007, age-sex specific and age-standardised MDS incidence rates from New Zealand were compared with those from Australia. Age-standardised incidence rates were calculated by the direct standardisation method and standardised rate ratios were compared at the 5, 1 and 0.1% levels. RESULTS:Diagnoses of MDS represented 1.3% of total cancer registrations in New Zealand and 1.0% in Australia. In both New Zealand and Australia, 86-87% of MDS cases were diagnosed in individuals ≥60 years of age, the incidence increased significantly with age, and males had a significantly higher age-standardised incidence rate (P < 0.001) than females. The incidence rate for New Zealand males was significantly higher (P < 0.001) than Australian males. In both New Zealand males and females, the age-standardised incidence rate of MDS was significantly higher (P < 0.05) than most other haematological neoplasms. CONCLUSIONS:In New Zealand and Australia, MDS is a common haematological neoplasm. The marked difference between male and female incidence rates, especially with advancing age, may provide insights into the causes of this disease.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Rodger EJ,Morison IMdoi
10.1111/j.1445-5994.2011.02619.xsubject
Has Abstractpub_date
2012-11-01 00:00:00pages
1235-42issue
11eissn
1444-0903issn
1445-5994journal_volume
42pub_type
杂志文章abstract::In this essay, I reflect on my experience as a multiple sclerosis patient in order to identify some of the unique challenges that chronic disability poses in the physician-patient relationship. I suggest that it is important to broaden the goals of the clinical encounter to incorporate personal (as opposed to simply b...
journal_title:Internal medicine journal
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