Placebo-controlled assessment of somnolence effect of cetirizine: a meta-analysis.

abstract：BACKGROUND:The endoscopic modified Lothrop procedure (EMLP) is commonly performed in recalcitrant frontal sinusitis, in part to achieve better penetration of medicated irrigations postoperatively. Although EMLP requires a septectomy for exposure, it is unknown whether septectomy size affects delivery of irrigations. In...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Tang D,Shah J,McBride J,Woodard TD,Sindwani R

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The relationship between olfactory function, rhinencephalon and forebrain changes in Kallmann syndrome (KS) have not been adequately investigated. We evaluated a large cohort of male KS patients using Sniffin' Sticks and MRI in order to study olfactory bulb (OB) volume, olfactory sulcus (OS) depth, cortical ...

journal_title：International forum of allergy & rhinology

authors： Ottaviano G,Cantone E,D'Errico A,Salvalaggio A,Citton V,Scarpa B,Favaro A,Sinisi AA,Liuzzi R,Bonanni G,Di Salle F,Elefante A,Manara R,Staffieri A,Martini A,Brunetti A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Medialization of the middle turbinate (MT) is an effective technique to prevent recurrent rhinosinusitis but could, in theory, reduce olfactory function by interfering the odorants to reach the olfactory mucosae. We performed a prospective randomized double-blind trial under the hypothesis that olfactory fun...

journal_title：International forum of allergy & rhinology

authors： Kim SW,Kim RB,Kang H,Cho HJ,Joo YH,Jeon YJ,Jeon SY

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Allergy-related illness impacts millions of individuals worldwide. Our objectives were to characterize current trends of clinical trials research relating to allergen immunotherapy and to describe the landscape of allergen immunotherapy in National Institutes of Health (NIH)-supported research inquiry. METH...

journal_title：International forum of allergy & rhinology

authors： Ramsey T,Lai W,Svider PF,Hojjat H,Eloy JA,Folbe AJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare 2010 access to, usage of, and attitudes toward image-guided surgery (IGS) for endoscopic sinus surgery and anterior skull-base surgery to those in 2005. METHODS:A mail survey of American Rhinologic Society (ARS) members was performed in January 2010. Results were compare...

journal_title：International forum of allergy & rhinology

authors： Justice JM,Orlandi RR

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Patients with eosinophilic chronic rhinosinusitis (ECRS) have been shown to have greater disease severity and poorer treatment outcomes after sinus surgery. Although the inflammatory pattern of ECRS is essential to diagnosing this subtype, there is currently no consensus for diagnosis. Our aim in this study ...

journal_title：International forum of allergy & rhinology

authors： McHugh T,Snidvongs K,Xie M,Banglawala S,Sommer D

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Olfactory dysfunction is 1 of the hallmark symptoms of chronic rhinosinusitis (CRS). Eosinophilic inflammation has been implicated as a potential causative factor. However, prior studies have been limited by retrospective study designs, concomitant use of systemic corticosteroids, and other confounding facto...

journal_title：International forum of allergy & rhinology

authors： Hauser LJ,Chandra RK,Li P,Turner JH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Requests from researchers for olfactory mucosal biopsies are increasing as a result of advances in the fields of neuroscience and stem cell biology. Published studies report variable rates of success in obtaining true olfactory tissue, often below 50%. In cases where biopsies are not obtained carefully and c...

journal_title：International forum of allergy & rhinology

authors： Holbrook EH,Rebeiz L,Schwob JE

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The most dramatic complication in endonasal surgery is inadvertent injury to the internal carotid artery (ICA) with massive bleeding. Nasal packing is the favored technique for control; however, this often causes complete carotid occlusion or carotid stenosis, contributing to the morbidity and mortality of t...

journal_title：International forum of allergy & rhinology

authors： Valentine R,Boase S,Jervis-Bardy J,Dones Cabral JD,Robinson S,Wormald PJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:A genetic basis to chronic rhinosinusitis (CRS) is postulated, but remains elusive. We have recently identified low levels of circulating CD8 lymphocytes as a frequent finding in difficult-to-treat or refractory CRS. In major histocompatibility complex 1 class 1 (MHC1) deficiency, low circulating levels of C...

journal_title：International forum of allergy & rhinology

authors： Alromaih S,Mfuna-Endam L,Bosse Y,Filali-Mouhim A,Desrosiers M

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The objective of this case series was to report what is to the best of our knowledge the first reports of nasopharyngeal and soft palate pseudomeningoceles tracking submucosally from the sphenoid sinus. METHODS:Analysis of cases through medical records. RESULTS:Two cases of middle-aged male patients presen...

journal_title：International forum of allergy & rhinology

authors： Lieberman SM,Ojo RB,Casiano RR

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Surgical treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) has evolved over the last decade as rhinologists have increasingly used topical steroid therapies and altered surgical techniques. It is important to understand the changes in success rates of surgery and frequency of revision endosco...

journal_title：International forum of allergy & rhinology

authors： Loftus CA,Soler ZM,Desiato VM,Koochakzadeh S,Yoo F,Storck KA,Schlosser RJ

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The pathogenic roles of fungus and bacteria in chronic rhinosinusitis (CRS) remain unclear. Recently, we described the bacterial ball, which is distinct from the fungus ball, as an unusual phenotype of bacterial infection. In this study, we investigated the clinical, histopathologic, and immunologic characte...

journal_title：International forum of allergy & rhinology

authors： Kim DK,Wi YC,Shin SJ,Kim KR,Kim DW,Cho SH

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The objective of this work was to better understand variations in perioperative management in endoscopic endonasal skull-base surgery (EESBS) and to identify trends in management based upon the practice patterns of North American Skull Base Society (NASBS) members. METHODS:A 29-question survey evaluating pe...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Lobo BC,Kshettry VR,D'Anza B,Woodard TD,Recinos PF,Snyderman CH,Sindwani R

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The role that bacterial biofilms might play in recalcitrant forms of chronic rhinosinusitis (CRS) is increasingly being recognized. However, the detection of bacteria existing in this form, using standard culture, is limited by their unique metabolically inactive properties. All current biofilm diagnostic mo...

journal_title：International forum of allergy & rhinology

authors： Foreman A,Jervis-Bardy J,Boase SJ,Tan L,Wormald PJ

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Chronic sinusitis is universal in cystic fibrosis (CF) and our current treatments are ineffective in reversing sinus disease. The objective of this work was to determine if increasing CF transmembrane conductance regulator (CFTR) activity by ivacaftor could treat CF sinus disease and assess its effect on pri...

journal_title：International forum of allergy & rhinology

authors： Chang EH,Tang XX,Shah VS,Launspach JL,Ernst SE,Hilkin B,Karp PH,Abou Alaiwa MH,Graham SM,Hornick DB,Welsh MJ,Stoltz DA,Zabner J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a local inflammatory process driven by eosinophils. Mucosal eosinophil count (MEC) has previously been demonstrated to be a reliable indicator of disease severity. We aim to evaluate use of MEC in guiding medical management of CRS after functional endoscopic sinus surgery (FES...

journal_title：International forum of allergy & rhinology

authors： Sharbel D,Li M,Unsal AA,Tadros SY,Lee J,Biddinger P,Holmes T,Kountakis SE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Diagnostic strategies employed for cases of cerebrospinal fluid (CSF) rhinorrhea vary widely due to limited evidence-based guidance. METHODS:A systematic review of the literature was performed using PubMed, EMBASE, and Cochrane databases from January 1990 through September 2014, to examine 9 diagnostic and ...

journal_title：International forum of allergy & rhinology

authors： Oakley GM,Alt JA,Schlosser RJ,Harvey RJ,Orlandi RR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-33 plays an important role in controlling immune responses in barrier tissues, and is a potent mediator of inflammatory diseases such as asthma, rheumatoid disease, and chronic rhinosinusitis. The aims of the present study were 2-fold: (1) to determine the stimulatory effect of tumor necrosi...

journal_title：International forum of allergy & rhinology

authors： Park IH,Park JH,Shin JM,Lee HM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The association between sinonasal microbiome and clinical outcomes of patients with chronic rhinosinusitis (CRS) is unclear. We performed a systematic review of prior studies evaluating the CRS microbiome in relation to clinical outcomes. METHODS:Computerized searches of PubMed/Medline, Cochrane, and EMBASE...

journal_title：International forum of allergy & rhinology

authors： Wang JC,Moore CA,Epperson MV,Sedaghat AR

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Nasal steroids are a critical part of the management of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) after endoscopic sinus surgery (ESS). Increasingly, practitioners are using budesonide respules delivered to the sinonasal cavities, which is an off-label use, in lieu of traditional nas...

journal_title：International forum of allergy & rhinology

authors： Neubauer PD,Schwam ZG,Manes RP

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Eosinophilic chronic rhinosinusitis (ECRS) is a disease characterized by eosinophilic inflammatory infiltrate and a local type 2 cytokine milieu. Current animal models fail to recapitulate many of the innate and adaptive immunologic hallmarks of the disease, thus hindering the development of effective therap...

journal_title：International forum of allergy & rhinology

authors： Tharakan A,Dobzanski A,London NR Jr,Khalil SM,Surya N,Lane AP,Ramanathan M Jr

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Knowledge of our immune system functions is critical for understanding allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies. METHODS:This review explains the current understanding of the basic immunology of the...

journal_title：International forum of allergy & rhinology

authors： Toskala E

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the pathogenesis of chronic rhinosinusitis (CRS) remains uncertain. Recent evidence suggests that bacteria are able to establish microcolonies within the underlying mucosa. However, to date there has been no systematic comparison of bacterial community composition and diversity in the...

journal_title：International forum of allergy & rhinology

authors： Kim RJ,Biswas K,Hoggard M,Taylor MW,Douglas RG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Previous studies have reviewed the safety of preparing and administering allergy injection immunotherapy in a physician's office, and showed no evidence of infectious complications. The current study examines the antimicrobial properties of the common additives used in preparation of multidose immunotherapy ...

journal_title：International forum of allergy & rhinology

authors： Gilbert KC,Sundareshan V,Bass RM,Lin SY

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Interleukin 13 (IL-13) is a pleiotropic cytokine that has been shown to be important in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and other type 2 inflammation-related diseases. Increased IL-13 expression can elicit several pro-inflammatory effects, including eosinophilia, and pat...

journal_title：International forum of allergy & rhinology

authors： Khalil SM,Bernstein I,Kulaga H,Gour N,Rowan N,Lajoie S,Lane AP

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:After endoscopic sinus surgery (ESS), endoscopy is used to gauge surgical success and clinical outcomes. Prior studies have not examined this topic prospectively using validated outcome metrics across multiple institutions. METHODS:A multi-institutional, prospective study of patients with chronic rhinosinus...

journal_title：International forum of allergy & rhinology

authors： Schlosser RJ,Storck K,Smith TL,Mace JC,Rudmik L,Shahangian A,Soler ZM

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The 5-year overall survival rate for patients with sinonasal cancers has remained around 50% for the last 3 decades. Prior studies on head and neck cancers have suggested that 1 reason for poor survival is the frequent development of second primary malignancies (SPMs). The purpose of this study is to assess ...

journal_title：International forum of allergy & rhinology

authors： Ganti A,Plitt MA,Kuan EC,Kuhar HN,Batra PS,Tajudeen BA

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. The principal signaling molecules involved in the apoptotic pathway are c-Jun N-terminal kinases (JNK). Although the JNK pathway has emerged as a key player in progra...

journal_title：International forum of allergy & rhinology

authors： Victores AJ,Chen M,Smith A,Lane AP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:This analysis explores the increasing heterogeneity of trends in allergy management under the premise that the practice of allergy has undergone significant changes in national economics, healthcare delivery, and treatment options from 2007 to 2016. METHODS:Centers for Medicare and Medicaid Services (CMS) d...

journal_title：International forum of allergy & rhinology

authors： Arianpour K,Svider PF,Yuhan B,Hooda Z,Eloy JA,Folbe AJ

更新日期：2018-05-21 00:00:00