Office-based olfactory mucosa biopsies.

abstract：BACKGROUND:The histological features of osteitis in chronic rhinosinusitis (CRS) in animal studies induced by bacterial inoculation into maxillary sinuses revealed inflammatory involvement of the underlying bone matrix and/or the Haversian system; however, human studies do not mention these findings. The objective of t...

journal_title：International forum of allergy & rhinology

authors： Snidvongs K,Earls P,Dalgorf D,Sacks R,Pratt E,Harvey RJ

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is an inflammatory disease process characterized by different phenotypes and histopathology profiles. Race and access to care have been implicated in CRS disease severity. Structural histopathology reporting may aid in delineating the inflammatory burden responsible for this effe...

journal_title：International forum of allergy & rhinology

authors： Kuhar HN,Ganti A,Eggerstedt M,Mahdavinia M,Gattuso P,Ghai R,Batra PS,Tajudeen BA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Increased frequency of migraine was reported in adults with allergic rhinitis (AR). Although migraine is less common in children than in adults, it can begin in early childhood and persist into adulthood. We conducted this population-based cohort study to investigate the incidence and subsequent risk of migr...

journal_title：International forum of allergy & rhinology

authors： Wang IC,Tsai JD,Lin CL,Shen TC,Li TC,Wei CC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Eosinophilic chronic rhinosinusitis (ECRS) is a disease characterized by eosinophilic inflammatory infiltrate and a local type 2 cytokine milieu. Current animal models fail to recapitulate many of the innate and adaptive immunologic hallmarks of the disease, thus hindering the development of effective therap...

journal_title：International forum of allergy & rhinology

authors： Tharakan A,Dobzanski A,London NR Jr,Khalil SM,Surya N,Lane AP,Ramanathan M Jr

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Endoscopic Draf 2B and Draf 3 frontal sinusotomies are frequently performed for chronic refractory frontal rhinosinusitis. The purpose of this study was to compare outcomes between Draf 2B and Draf 3 procedures. METHODS:A retrospective cohort study was conducted comparing patients undergoing bilateral Draf ...

journal_title：International forum of allergy & rhinology

authors： Patel VS,Choby G,Shih LC,Patel ZM,Nayak JV,Hwang PH

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Topical intranasal corticosteroid sprays (INCSs) are standard treatment for nasal polyps (NPs), but their efficacy is reduced by poor patient compliance and impaired access of drug to the sinus mucosa. A corticosteroid-eluting sinus implant was designed to address these limitations in patients with recurrent...

journal_title：International forum of allergy & rhinology

authors： Kern RC,Stolovitzky JP,Silvers SL,Singh A,Lee JT,Yen DM,Iloreta AMC Jr,Langford FPJ,Karanfilov B,Matheny KE,Stambaugh JW,Gawlicka AK,RESOLVE II study investigators.

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Optimizing the intranasal distribution of nasal steroid spray (NS) is important in managing patients with allergic rhinitis (AR). Using a 3-dimensional computational model of the human nose, we found that inspiratory airflow improved particle distribution by 86%. We hence designed a study to determine if the...

journal_title：International forum of allergy & rhinology

authors： Tay SY,Chao SS,Mark KT,Wang Y

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The ciprofloxacin-coated sinus stent (CSS) has unique therapeutic potential to deliver antibiotics to the sinuses. The objective of this study is to evaluate the efficacy of the CSS stent in eliminating Pseudomonas aeruginosa infection in a rabbit model of sinusitis. METHODS:A ciprofloxacin-eluting sinus st...

journal_title：International forum of allergy & rhinology

authors： Cho DY,Lim DJ,Mackey C,Skinner D,Weeks C,Gill GS,Hergenrother RW,Swords WE,Woodworth BA

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) in aspirin-exacerbated respiratory disease (AERD) represents a recalcitrant form of sinonasal inflammation for which a multidisciplinary consensus on patient management has not been reached. Several medical interventions have been investigated, but a formal comprehensive evaluati...

journal_title：International forum of allergy & rhinology

authors： Levy JM,Rudmik L,Peters AT,Wise SK,Rotenberg BW,Smith TL

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. The principal signaling molecules involved in the apoptotic pathway are c-Jun N-terminal kinases (JNK). Although the JNK pathway has emerged as a key player in progra...

journal_title：International forum of allergy & rhinology

authors： Victores AJ,Chen M,Smith A,Lane AP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The 5-year overall survival rate for patients with sinonasal cancers has remained around 50% for the last 3 decades. Prior studies on head and neck cancers have suggested that 1 reason for poor survival is the frequent development of second primary malignancies (SPMs). The purpose of this study is to assess ...

journal_title：International forum of allergy & rhinology

authors： Ganti A,Plitt MA,Kuan EC,Kuhar HN,Batra PS,Tajudeen BA

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Povidone-iodine (PVP-I) is well known as an antiseptic and exhibits extensive activity against various pathogens. However, due to its uniquely unpleasant nature, it cannot be used locally to deactivate various sinonasal pathogens. Therefore, we developed a PVP-I composite that blocks the unpleasant odor of P...

journal_title：International forum of allergy & rhinology

authors： Jeronimo LP,Choi MR,Yeon SH,Park SK,Yoon YH,Choi SH,Kim HJ,Jang IT,Park JK,Rha KS,Kim YM

更新日期：2020-07-01 00:00:00

abstract：:Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as coronavirus disease 2019 (COVID-19). The possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might cause olfactory dysfunction is certainly plausible. Patients presenting to specialized ...

journal_title：International forum of allergy & rhinology

authors： Soler ZM,Patel ZM,Turner JH,Holbrook EH

更新日期：2020-07-01 00:00:00

abstract：:Recent evidence has demonstrated an expanding role of respiratory epithelial cells in immune surveillance and modulation. Studies have been focusing on the earliest events that link epithelial injury to downstream inflammatory responses. Cytokines produced by and released from respiratory epithelial cells are among th...

journal_title：International forum of allergy & rhinology

authors： Patel NN,Kohanski MA,Maina IW,Workman AD,Herbert DR,Cohen NA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Little is known about the use of allergy and asthma medications in older adults. This study aimed to assess the prevalence of use of these medications in older adults and evaluate predictors of their use. METHODS:Cross-sectional study using data from the National Social Life, Health, and Aging Project (NSHA...

journal_title：International forum of allergy & rhinology

authors： Ajmani GS,Wroblewski KE,Baroody FM,Naclerio RM,Pinto JM

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Patients with refractory chronic rhinosinusitis (RCRS) have persistent symptoms despite best medical therapy. Some evidence suggests continued medical therapy (CMT) is appropriate for patients with RCRS. The primary objective of this study was to evaluate the clinical impact of CMT in patients with RCRS who ...

journal_title：International forum of allergy & rhinology

authors： Smith KA,Rudmik L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Debate still persists on the relation between olfactory bulb volume (OBV) and olfactory function. Many studies suggest that olfactory deprivation decreases the OBV. The aim of this study was to compare the olfactory threshold and OBV of patients with nasal polyps to healthy individuals and to evaluate the im...

journal_title：International forum of allergy & rhinology

authors： Sadeghi M,Amali A,Ezabadi SR,Motiee-Langroudi M,Farshchi S,Mokhtari Z

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Environmental factors such as inhaled pollutants like cigarette smoke may play a significant role in diseases of the upper airway including chronic rhinosinusitis (CRS). The objectives of this review are to summarize prior studies that describe the correlation between active smoking and secondhand smoke (SHS...

journal_title：International forum of allergy & rhinology

authors： Reh DD,Higgins TS,Smith TL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The role that bacterial biofilms might play in recalcitrant forms of chronic rhinosinusitis (CRS) is increasingly being recognized. However, the detection of bacteria existing in this form, using standard culture, is limited by their unique metabolically inactive properties. All current biofilm diagnostic mo...

journal_title：International forum of allergy & rhinology

authors： Foreman A,Jervis-Bardy J,Boase SJ,Tan L,Wormald PJ

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Anatomic limitations complicate complete eradication of debris from the maxillary sinus using an exclusively transnasal (TN) endoscopic technique. Creation of a canine fossa trephination (CFT) permits a more direct approach than removal via the maxillary ostium. METHODS:Microdebrider eradication of debris co...

journal_title：International forum of allergy & rhinology

authors： Feldt BA,McMains KC,Weitzel EK

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The treatment of the middle turbinate (MT) during endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) remains a contentious issue with arguments both for and against its resection. The purpose of this study was to examine the clinical impact of partial MT resection (PMTR) during ESS, paying parti...

journal_title：International forum of allergy & rhinology

authors： Tan NC,Goggin R,Psaltis AJ,Wormald PJ

更新日期：2018-04-06 00:00:00

abstract：BACKGROUND:The aim of this study was to identify and evaluate adverse clinical outcomes following office-based sclerotherapy using sodium tetradecyl sulfate (STS) for epistaxis due to hereditary hemorrhagic telangiectasias (HHT or Osler-Weber-Rendu). METHODS:A retrospective chart review of 36 adult patients treated wi...

journal_title：International forum of allergy & rhinology

authors： Hanks JE,Hunter D,Goding GS Jr,Boyer HC

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Endoscopic repair of anterior skull-base defects has become the gold standard for management of cerebrospinal fluid (CSF) rhinorrhea. Both improved techniques and adjuvant therapies have led to accepted success rates of greater than 90%. As management has evolved, shorter hospitalizations have been required ...

journal_title：International forum of allergy & rhinology

authors： Adams AS,Francis DO,Russell PT

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants. METHODS:A search of the U.S. National Library of Medicine (PubMed) database was performed for th...

journal_title：International forum of allergy & rhinology

authors： Manes RP,Ryan MW,Batra PS,Mendelsohn D,Fang YV,Marple BF

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Subcutaneous immunotherapy (SCIT) demands a significant time commitment on the part of the patient, especially during the escalation period when weekly visits are required. Many patients refuse or discontinue treatment in spite of the demonstrated clinical efficacy of SCIT. Understanding the factors that aff...

journal_title：International forum of allergy & rhinology

authors： Jourdy DN,Reisacher WR

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Surgical management of the superior turbinate (ST) is required to access the sella in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary adenoma. Two common ST management techniques include partial resection of the ST (PRST) and intentional lateralization of the ST (ILST). Given the concentrat...

journal_title：International forum of allergy & rhinology

authors： Li P,Luo K,Zhang Q,Wang Z

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Insufficiency of the nasal valve is increasingly being recognized as a cause of nasal airway obstruction. The condition is associated with many symptoms, including nasal congestion, sleep disturbance, snoring, and an overall decline in quality of life (QoL). An in-office, minimally invasive radiofrequency tr...

journal_title：International forum of allergy & rhinology

authors： Ephrat M,Jacobowitz O,Driver M

更新日期：2020-08-09 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis with nasal polyps (CRSwNP) is prolonged inflammation of the sinonasal mucosa. Interleukin-32 (IL-32) is involved in the pathogenesis of chronic lung inflammatory diseases. The aim of study is to compare the expression level of IL-32 in normal nasal mucosa and CRSwNP and to investigate ...

journal_title：International forum of allergy & rhinology

authors： Cho JS,Kim JA,Park JH,Park IH,Han IH,Lee HM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the pathogenesis of chronic rhinosinusitis (CRS) remains uncertain. Recent evidence suggests that bacteria are able to establish microcolonies within the underlying mucosa. However, to date there has been no systematic comparison of bacterial community composition and diversity in the...

journal_title：International forum of allergy & rhinology

authors： Kim RJ,Biswas K,Hoggard M,Taylor MW,Douglas RG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Although nasal congestion is among the most common symptoms in subjects suffering from nasal diseases, relatively few data on normal airflow resistance are available for reference, especially in healthy Chinese subjects. The aim of present study was therefore to objectively measure the normal airflow resista...

journal_title：International forum of allergy & rhinology

authors： Ren L,Zhang L,Duan S,Zhang W,Zhang Y

更新日期：2018-11-01 00:00:00