Characterization of a novel, papain-inducible murine model of eosinophilic rhinosinusitis.

abstract：BACKGROUND:Orbital cavernous hemangiomas (OCH) are the most common adult orbital tumor and represent an ideal index lesion for endonasal orbital tumor surgery. In order to standardize outcomes reporting, an anatomic-based staging system was developed. METHODS:An international, multidisciplinary panel of 23 experts in ...

journal_title：International forum of allergy & rhinology

authors： El Rassi E,Adappa ND,Battaglia P,Castelnuovo P,Dallan I,Freitag SK,Gardner PA,Lenzi R,Lubbe D,Metson R,Moe KS,Muscatello L,Mustak H,Nogueira JF,Palmer JN,Prepageran N,Ramakirshnan VR,Sacks R,Snyderman CH,Stefko ST,

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Nasal steroids are a critical part of the management of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) after endoscopic sinus surgery (ESS). Increasingly, practitioners are using budesonide respules delivered to the sinonasal cavities, which is an off-label use, in lieu of traditional nas...

journal_title：International forum of allergy & rhinology

authors： Neubauer PD,Schwam ZG,Manes RP

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Most data on sinonasal mucosal melanoma come from small institutional studies, and therefore optimal treatment methods are not well understood. The purpose of this study was to analyze the association between treatment and survival in sinonasal mucosal melanoma. METHODS:Six hundred ninety-five patients diag...

journal_title：International forum of allergy & rhinology

authors： Konuthula N,Khan MN,Parasher A,Del Signore A,Genden EM,Govindaraj S,Iloreta AM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The immunologic mechanisms driving inflammation in the upper airways of patients with chronic rhinosinusitis (CRS) are poorly understood. Previous studies have shown that B cells and immunoglobulin E (IgE) levels are elevated in the nasal tissue of patients with atopic chronic rhinosinusitis without nasal po...

journal_title：International forum of allergy & rhinology

authors： Rashan AR,Goshn E,Peterson A,Yang Y,Phillips M,Sahaf B,Herzenberg L,Nayak JV

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Previous studies have consistently shown that females with chronic rhinosinusitis (CRS) have a greater CRS symptom burden than males with CRS. Our objective was to determine whether differential disease perception could explain this phenomenon. METHODS:A total of 500 participants (239 males, 261 females) wi...

journal_title：International forum of allergy & rhinology

authors： Phillips KM,Bergmark RW,Hoehle LP,Shu ET,Caradonna DS,Gray ST,Sedaghat AR

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to compare the absolute breaking strength of various soft tissue skull base (SB) repairs in an in vitro porcine model. METHODS:A burst pressure (BP) testing system was designed using an axial loading force to create increasing hydraulic pressure. Defects measuring 0.5 × 0.5 cm w...

journal_title：International forum of allergy & rhinology

authors： Fandiño M,Macdonald K,Singh D,Whyne C,Witterick I

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Previous studies have shown controversial results of topical amphotericin B (AMB) nasal irrigation for chronic rhinosinusitis (CRS). The purpose of this study was to evaluate the efficacy of 200 μg/mL AMB nasal irrigation as an adjuvant therapy after functional endoscopic sinus surgery (FESS). METHODS:Patie...

journal_title：International forum of allergy & rhinology

authors： Jiang RS,Twu CW,Liang KL

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:After endoscopic sinus surgery (ESS), endoscopy is used to gauge surgical success and clinical outcomes. Prior studies have not examined this topic prospectively using validated outcome metrics across multiple institutions. METHODS:A multi-institutional, prospective study of patients with chronic rhinosinus...

journal_title：International forum of allergy & rhinology

authors： Schlosser RJ,Storck K,Smith TL,Mace JC,Rudmik L,Shahangian A,Soler ZM

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Oncocytomas and oncocytic carcinomas are rare tumors of the sinonasal cavity with the propensity for local invasion. This report and systematic review details a case of a nasal oncocytoma involving the lacrimal sac and provides an update of the current literature. METHODS:A systematic literature review was ...

journal_title：International forum of allergy & rhinology

authors： Hodzic Z,Rowan NR,Kashiwazaki R,Willson TJ,Wang EW,Lee SE

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Olfactory dysfunction is 1 of the hallmark symptoms of chronic rhinosinusitis (CRS). Eosinophilic inflammation has been implicated as a potential causative factor. However, prior studies have been limited by retrospective study designs, concomitant use of systemic corticosteroids, and other confounding facto...

journal_title：International forum of allergy & rhinology

authors： Hauser LJ,Chandra RK,Li P,Turner JH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Inadequate efficacy of current intranasal steroids in chronic rhinosinusitis (CRS) is attributable to ineffective and/or inconsistent drug delivery to target anatomic sites. A new exhalation delivery system with fluticasone (EDS-FLU) may improve outcomes by significantly increasing superior/posterior cortico...

journal_title：International forum of allergy & rhinology

authors： Palmer JN,Jacobson KW,Messina JC,Kosik-Gonzalez C,Djupesland PG,Mahmoud RA

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a chronic systemic allergic disease with an association reported between allergy and anxiety. The objective of the current study was therefore to investigate and retrospectively evaluate the factors that may possibly induce state and trait anxiety among patients with AR and vasomoto...

journal_title：International forum of allergy & rhinology

authors： Xi L,Cao F,Zhang Y,Zhang L

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The 5-year overall survival rate for patients with sinonasal cancers has remained around 50% for the last 3 decades. Prior studies on head and neck cancers have suggested that 1 reason for poor survival is the frequent development of second primary malignancies (SPMs). The purpose of this study is to assess ...

journal_title：International forum of allergy & rhinology

authors： Ganti A,Plitt MA,Kuan EC,Kuhar HN,Batra PS,Tajudeen BA

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Knowledge of our immune system functions is critical for understanding allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies. METHODS:This review explains the current understanding of the basic immunology of the...

journal_title：International forum of allergy & rhinology

authors： Toskala E

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The effects of desloratadine-montelukast combination on quality of life (QoL) and nasal airflow of patients with perennial allergic rhinitis (PAR) has not been reported. The objective of this work was investigate the efficacy of desloratadine-montelukast combination on nasal obstruction and health-related qu...

journal_title：International forum of allergy & rhinology

authors： Cingi C,Oghan F,Eskiizmir G,Yaz A,Ural A,Erdogmus N

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is strongly associated with comorbid asthma. This study compares early-onset and late-onset asthma in a CRS population using patient-reported and clinical characteristics. METHODS:At enrollment into a clinical registry, CRS patients completed the 22-item Sino-Nasal Outcome Test ...

journal_title：International forum of allergy & rhinology

authors： John Staniorski C,Price CPE,Weibman AR,Welch KC,Conley DB,Shintani-Smith S,Stevens WW,Peters AT,Grammer L,Lidder AK,Schleimer RP,Kern RC,Tan BK

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The ciprofloxacin-coated sinus stent (CSS) has unique therapeutic potential to deliver antibiotics to the sinuses. The objective of this study is to evaluate the efficacy of the CSS stent in eliminating Pseudomonas aeruginosa infection in a rabbit model of sinusitis. METHODS:A ciprofloxacin-eluting sinus st...

journal_title：International forum of allergy & rhinology

authors： Cho DY,Lim DJ,Mackey C,Skinner D,Weeks C,Gill GS,Hergenrother RW,Swords WE,Woodworth BA

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Endoscopic repair of anterior skull-base defects has become the gold standard for management of cerebrospinal fluid (CSF) rhinorrhea. Both improved techniques and adjuvant therapies have led to accepted success rates of greater than 90%. As management has evolved, shorter hospitalizations have been required ...

journal_title：International forum of allergy & rhinology

authors： Adams AS,Francis DO,Russell PT

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-9 and IL-17C have been known to play a role in allergic inflammation, yet, their roles in chronic rhinosinusitis (CRS) are not well defined. IL-9 induces changes in epithelial cell gene expression leading to goblet cell metaplasia, whereas IL-17C is functionally distinct in that its expressi...

journal_title：International forum of allergy & rhinology

authors： Olcott CM,Han JK,Cunningham TD,Franzese CB

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The objective of this work was to better understand variations in perioperative management in endoscopic endonasal skull-base surgery (EESBS) and to identify trends in management based upon the practice patterns of North American Skull Base Society (NASBS) members. METHODS:A 29-question survey evaluating pe...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Lobo BC,Kshettry VR,D'Anza B,Woodard TD,Recinos PF,Snyderman CH,Sindwani R

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:This study reviews the published literature related to management of sinonasal chondrosarcoma. Clinical presentation, demographics, radiographic diagnosis, treatment, and management outcomes of this uncommon disease are reported. METHODS:A systematic review of studies for sinonasal chondrosarcoma from 1950 ...

journal_title：International forum of allergy & rhinology

authors： Khan MN,Husain Q,Kanumuri VV,Boghani Z,Patel CR,Liu JK,Eloy JA

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The lateral nasal wall (LNW) flap provides vascularized endonasal reconstruction primarily in revision surgery. Although the harvesting technique and reconstructive surface have been reported, the arterial supply to the LNW flap and its clinical implications is not well defined. This study presents anatomica...

journal_title：International forum of allergy & rhinology

authors： Lavigne P,Vega MB,Ahmed OH,Gardner PA,Snyderman CH,Wang EW

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Diagnostic strategies employed for cases of cerebrospinal fluid (CSF) rhinorrhea vary widely due to limited evidence-based guidance. METHODS:A systematic review of the literature was performed using PubMed, EMBASE, and Cochrane databases from January 1990 through September 2014, to examine 9 diagnostic and ...

journal_title：International forum of allergy & rhinology

authors： Oakley GM,Alt JA,Schlosser RJ,Harvey RJ,Orlandi RR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:In this prospective, multicenter, randomized, controlled, double-blind study, we investigated the impact of a mobile patient engagement application on health outcomes and quality of life in allergic rhinitis (AR) and asthma patients. METHODS:In total, 327 patients with diagnoses of persistent AR or mild-to-...

journal_title：International forum of allergy & rhinology

authors： Cingi C,Yorgancioglu A,Cingi CC,Oguzulgen K,Muluk NB,Ulusoy S,Orhon N,Yumru C,Gokdag D,Karakaya G,Çelebi Ş,Çobanoglu HB,Unlu H,Aksoy MA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Little is known regarding the role of the microbiome of the paranasal sinuses and its contribution to sinus mucosal health and disease. Consequently, we examined the microbiome of chronic rhinosinusitis patients with polyps (CRSwNP) and a control population to provide new insights into the microbiota associa...

journal_title：International forum of allergy & rhinology

authors： Gan W,Yang F,Tang Y,Zhou D,Qing D,Hu J,Liu S,Liu F,Meng J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The role that bacterial biofilms might play in recalcitrant forms of chronic rhinosinusitis (CRS) is increasingly being recognized. However, the detection of bacteria existing in this form, using standard culture, is limited by their unique metabolically inactive properties. All current biofilm diagnostic mo...

journal_title：International forum of allergy & rhinology

authors： Foreman A,Jervis-Bardy J,Boase SJ,Tan L,Wormald PJ

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis with nasal polyps (CRSwNP) is prolonged inflammation of the sinonasal mucosa. Interleukin-32 (IL-32) is involved in the pathogenesis of chronic lung inflammatory diseases. The aim of study is to compare the expression level of IL-32 in normal nasal mucosa and CRSwNP and to investigate ...

journal_title：International forum of allergy & rhinology

authors： Cho JS,Kim JA,Park JH,Park IH,Han IH,Lee HM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Nasal polyposis is characterized by persistent inflammation but the pathogenesis is complex and still debatable. Autophagy has been associated with many human health problems including chronic inflammatory airway diseases. Whether autophagy plays a role in nasal polyps and could be a therapeutic target is co...

journal_title：International forum of allergy & rhinology

authors： Chen JY,Hour TC,Yang SF,Chien CY,Chen HR,Tsai KL,Ko JY,Wang LF

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Debate still persists on the relation between olfactory bulb volume (OBV) and olfactory function. Many studies suggest that olfactory deprivation decreases the OBV. The aim of this study was to compare the olfactory threshold and OBV of patients with nasal polyps to healthy individuals and to evaluate the im...

journal_title：International forum of allergy & rhinology

authors： Sadeghi M,Amali A,Ezabadi SR,Motiee-Langroudi M,Farshchi S,Mokhtari Z

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a common condition encountered in primary care medicine and is estimated to affect 12.5% of the United States population. This study aims to compare methods of assessing health utility in CRS. METHODS:A cross-sectional sample of CRS patients (n = 137) were interviewed using d...

journal_title：International forum of allergy & rhinology

authors： Ference EH,Stubbs V,Lidder AK,Chandra RK,Conley D,Avila PC,Hirsch AG,Min JY,Smith SS,Kern RC,Tan BK

更新日期：2015-10-01 00:00:00