The difference in nasal bacterial microbiome diversity between chronic rhinosinusitis patients with polyps and a control population.

abstract：BACKGROUND:Diagnostic nasal endoscopy is a routine measure of sinonasal inflammation in patients with chronic rhinosinusitis (CRS). Although multiple staging systems have been proposed and evaluated, evidence of association between concurrent symptoms and endoscopic findings remains discordant. The goal of this study i...

journal_title：International forum of allergy & rhinology

authors： DeConde AS,Bodner TE,Mace JC,Alt JA,Rudmik L,Smith TL

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Although nasal congestion is among the most common symptoms in subjects suffering from nasal diseases, relatively few data on normal airflow resistance are available for reference, especially in healthy Chinese subjects. The aim of present study was therefore to objectively measure the normal airflow resista...

journal_title：International forum of allergy & rhinology

authors： Ren L,Zhang L,Duan S,Zhang W,Zhang Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Povidone-iodine (PVP-I) is well known as an antiseptic and exhibits extensive activity against various pathogens. However, due to its uniquely unpleasant nature, it cannot be used locally to deactivate various sinonasal pathogens. Therefore, we developed a PVP-I composite that blocks the unpleasant odor of P...

journal_title：International forum of allergy & rhinology

authors： Jeronimo LP,Choi MR,Yeon SH,Park SK,Yoon YH,Choi SH,Kim HJ,Jang IT,Park JK,Rha KS,Kim YM

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants. METHODS:A search of the U.S. National Library of Medicine (PubMed) database was performed for th...

journal_title：International forum of allergy & rhinology

authors： Manes RP,Ryan MW,Batra PS,Mendelsohn D,Fang YV,Marple BF

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Arterial epistaxis is commonly seen in the rhinology clinic and can have a significant impact on quality of life. Previous studies have explored various therapies to address epistaxis. METHODS:Patients were treated in the outpatient clinic or operating room by microwave ablation (MWA) with a 2450-MHz cooled...

journal_title：International forum of allergy & rhinology

authors： Lou ZC,Dong Y,Lou ZH

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a frequently observed condition in patients with immunodeficiency secondary to tumor necrosis factor alpha inhibitors (TNFαis). The histologic features of CRS caused by TNFαis have yet to be determined and may have important implications in understanding the pathophysiology of...

journal_title：International forum of allergy & rhinology

authors： Papagiannopoulos P,Devins K,Tong CCL,Yver C,Patel NN,Kuhar HN,Bosso JV,Kohanski MA,Tajudeen BA,Kuan EC,Batra PS,Cohen NA,Kennedy DW,Palmer JN,Montone K,Adappa ND

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Interleukin 13 (IL-13) is a pleiotropic cytokine that has been shown to be important in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and other type 2 inflammation-related diseases. Increased IL-13 expression can elicit several pro-inflammatory effects, including eosinophilia, and pat...

journal_title：International forum of allergy & rhinology

authors： Khalil SM,Bernstein I,Kulaga H,Gour N,Rowan N,Lajoie S,Lane AP

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Aspirin-exacerbated respiratory disease (AERD) is characterized by chronic eosinophilic rhinosinusitis, nasal polyps, asthma, and respiratory sensitivity to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). In addition to sensitivity to aspirin and NSAIDs, the majority of patients with AERD have bee...

journal_title：International forum of allergy & rhinology

authors： Glicksman JT,Parasher AK,Doghramji L,Brauer D,Waldram J,Walters K,Bulva J,Palmer JN,Adappa ND,White AA,Bosso JV

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the pathogenesis of chronic rhinosinusitis (CRS) remains uncertain. Recent evidence suggests that bacteria are able to establish microcolonies within the underlying mucosa. However, to date there has been no systematic comparison of bacterial community composition and diversity in the...

journal_title：International forum of allergy & rhinology

authors： Kim RJ,Biswas K,Hoggard M,Taylor MW,Douglas RG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the impact of bilateral inferior turbinate reduction (BITR) on patient-reported quality of life (QOL) following endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). METHODS:This was a prospective cohort study. Patients with CRS, who were recruited from...

journal_title：International forum of allergy & rhinology

authors： Scangas GA,Bleier BS,Husain Q,Holbrook EH,Gray ST,Metson R

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Previous studies have shown controversial results of topical amphotericin B (AMB) nasal irrigation for chronic rhinosinusitis (CRS). The purpose of this study was to evaluate the efficacy of 200 μg/mL AMB nasal irrigation as an adjuvant therapy after functional endoscopic sinus surgery (FESS). METHODS:Patie...

journal_title：International forum of allergy & rhinology

authors： Jiang RS,Twu CW,Liang KL

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Osteitis is a feature of chronic rhinosinusitis (CRS) and often associated with recalcitrant disease. Radiological characteristics of osteitic sinus changes are commonly reported in practice but the clinical and pathologic significance is poorly defined. The objective of this study was to correlate the Kenne...

journal_title：International forum of allergy & rhinology

authors： Snidvongs K,McLachlan R,Sacks R,Earls P,Harvey RJ

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Currently, limited literature exists about sinonasal adenoid cystic carcinoma (SNACC). In this study, we analyze the demographics, survival, and treatment efficacy of this rare entity. METHODS:Our study was a retrospective population-based analysis of SNACC in the Surveillance, Epidemiology, and End Results...

journal_title：International forum of allergy & rhinology

authors： Unsal AA,Chung SY,Zhou AH,Baredes S,Eloy JA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The extracellular matrix (ECM) is a potentially important component of mucosal immunity. ECM dysregulation in chronic rhinosinusitis (CRS) is suggested by genomewide association studies identifying ECM genes as top candidates. Further support is afforded by the demonstration of increased expression of perios...

journal_title：International forum of allergy & rhinology

authors： Zhang W,Hubin G,Endam LM,Al-Mot S,Filali-Mouhim A,Desrosiers M

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The objective of the evidence base review was to systematically evaluate the literature to elucidate the potential role of oral antifungal therapy in management of chronic rhinosinusitis (CRS) and its subtypes. METHODS:Articles for inclusion were identified by query of appropriate search terms in the PubMed...

journal_title：International forum of allergy & rhinology

authors： Thanasumpun T,Batra PS

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Trefoil factor family (TFF) peptides are mucin-associated secretory products that are produced in the airways and gastrointestinal tract. These peptides appear to play an important role in mucosal healing and epithelial protection and are overexpressed in chronically inflamed gastrointestinal tissues. We hyp...

journal_title：International forum of allergy & rhinology

authors： Li P,Turner JH

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:It has been found that the most common adverse reaction which occurs more frequently on cetirizine than on placebo is somnolence. However, the somnolence rate varied widely among different studies. The objective of this study was to assess the somnolence effect of cetirizine 10 mg daily compared to placebo i...

journal_title：International forum of allergy & rhinology

authors： Du Q,Zhou Y

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:There has been no study investigating nonsteroidal anti-inflammatory drugs (NSAIDs)-exacerbated respiratory disease (NERD) exclusively in childhood. Therefore, in the current study, the authors aimed to evaluate the diagnostic features, clinical characteristics, and follow-up of adolescents diagnosed with NE...

journal_title：International forum of allergy & rhinology

authors： Ertoy Karagol HI,Yilmaz O,Topal E,Ceylan A,Bakirtas A

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The management of chronic rhinosinusitis with nasal polyposis (CRSwNP) becomes unclear when patients require multiple courses of corticosteroids to maintain quality of life. Repeated courses of corticosteroids carry increased risks to patients. Although endoscopic sinus surgery (ESS) is an effective therapeu...

journal_title：International forum of allergy & rhinology

authors： Leung RM,Dinnie K,Smith TL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Antibiotics are commonly used in the management of both acute rhinosinusitis and acute exacerbations of chronic rhinosinusitis. With their common use, they have become the leading medication for litigation. It is crucial for the provider to be familiar with potential complications and the medico-legal ramifi...

journal_title：International forum of allergy & rhinology

authors： Poetker DM,Smith TL

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Anatomic limitations complicate complete eradication of debris from the maxillary sinus using an exclusively transnasal (TN) endoscopic technique. Creation of a canine fossa trephination (CFT) permits a more direct approach than removal via the maxillary ostium. METHODS:Microdebrider eradication of debris co...

journal_title：International forum of allergy & rhinology

authors： Feldt BA,McMains KC,Weitzel EK

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Industry outreach promotes awareness of novel technologies. However, concerns have been raised that such relationships may also unduly impact medical decision-making. Our objective in this study was to evaluate industry relationships among practitioners who frequently employ balloon dilation (BD), characteri...

journal_title：International forum of allergy & rhinology

authors： Eloy JA,Svider PF,Bobian M,Harvey RJ,Gray ST,Baredes S,Folbe AJ

更新日期：2017-09-01 00:00:00

abstract：:Recent evidence has demonstrated an expanding role of respiratory epithelial cells in immune surveillance and modulation. Studies have been focusing on the earliest events that link epithelial injury to downstream inflammatory responses. Cytokines produced by and released from respiratory epithelial cells are among th...

journal_title：International forum of allergy & rhinology

authors： Patel NN,Kohanski MA,Maina IW,Workman AD,Herbert DR,Cohen NA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether anterior rhinoscopy (AR), nasal endoscopy (NE) and paranasal sinus computed tomography (PNS CT) can predict other sinonasal obstructive pathologies in the setting of nasal septal deviation (NSD), and to evaluate the impact of preoperative PNS CT on the decision ...

journal_title：International forum of allergy & rhinology

authors： Günbey E,Günbey HP,Uygun S,Karabulut H,Cingi C

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Treatment options for chronic rhinosinusitis with recurrent polyposis (CRSwNP) after endoscopic sinus surgery (ESS) are limited, and include frequent use of systemic steroids and revision surgery. A bioabsorbable, steroid-eluting implant was studied for its ability to dilate sinuses obstructed by polyps and ...

journal_title：International forum of allergy & rhinology

authors： Lavigne F,Miller SK,Gould AR,Lanier BJ,Romett JL

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Patients with refractory chronic rhinosinusitis (RCRS) have persistent symptoms despite best medical therapy. Some evidence suggests continued medical therapy (CMT) is appropriate for patients with RCRS. The primary objective of this study was to evaluate the clinical impact of CMT in patients with RCRS who ...

journal_title：International forum of allergy & rhinology

authors： Smith KA,Rudmik L

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:This study describes safety outcomes of pediatric endoscopic sinus surgery (ESS) to identify risk factors for 30-day postoperative adverse events using the National Surgical Quality Improvement Program-Pediatric (NSQIP-P) database. METHODS:We performed a retrospective cohort study involving patients in th...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Li L,Rhee D,Jatana KR,Shah RK,Boss EF

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Frontal sinus cerebrospinal fluid (CSF) leaks have traditionally been repaired via open procedures (eg, osteoplastic flap or cranialization). Advancements in instrumentation, technique, and experience have improved the feasibility of repairing frontal sinus skull-base defects using an endoscopic approach. Th...

journal_title：International forum of allergy & rhinology

authors： Jones V,Virgin F,Riley K,Woodworth BA

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Spacers are inserted into the middle meatal space (MMS) following functional endoscopic sinus surgery (FESS) to prevent lateralization of the middle turbinate, scarring, and synechiae. Our objective was to determine if the incidence of postoperative synechiae, facial pain/discomfort, pain during spacer remov...

journal_title：International forum of allergy & rhinology

authors： Manji J,Habib AR,Macias-Valle L,Finkelstein A,Alsaleh S,Dadgostar A,Al-Asousi F,Okpaleke C,Javer AR

更新日期：2018-03-30 00:00:00

abstract：BACKGROUND:Oncocytomas and oncocytic carcinomas are rare tumors of the sinonasal cavity with the propensity for local invasion. This report and systematic review details a case of a nasal oncocytoma involving the lacrimal sac and provides an update of the current literature. METHODS:A systematic literature review was ...

journal_title：International forum of allergy & rhinology

authors： Hodzic Z,Rowan NR,Kashiwazaki R,Willson TJ,Wang EW,Lee SE

更新日期：2017-05-01 00:00:00