Interleukin-9 and interleukin-17C in chronic rhinosinusitis.

abstract：BACKGROUND:Sinonasal bitter taste receptors (T2Rs) contribute to upper airway innate immunity and correlate with chronic rhinosinusitis (CRS) clinical outcomes. A subset of T2Rs expressed on sinonasal solitary chemosensory cells (SCCs) are activated by denatonium, resulting in a calcium-mediated secretion of bactericid...

journal_title：International forum of allergy & rhinology

authors： Carey RM,Workman AD,Hatten KM,Siebert AP,Brooks SG,Chen B,Adappa ND,Palmer JN,Kennedy DW,Lee RJ,Cohen NA

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Over 45 million Americans suffer from recurrent headaches, and an estimated $11.9 million was spent on doctor's visits for rhinogenic pain last year. Sphenopalatine blocks have been described for various facial pain syndromes, but their use and the type of blockade agents remain controversial. The objective ...

journal_title：International forum of allergy & rhinology

authors： Rodman R,Dutton J

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Arterial epistaxis is commonly seen in the rhinology clinic and can have a significant impact on quality of life. Previous studies have explored various therapies to address epistaxis. METHODS:Patients were treated in the outpatient clinic or operating room by microwave ablation (MWA) with a 2450-MHz cooled...

journal_title：International forum of allergy & rhinology

authors： Lou ZC,Dong Y,Lou ZH

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The correct use of inhalation devices is essential for successful therapy. We aimed to evaluate the skills in the use of a spacer device with an metered-dose inhaler (MDI) and factors that influence this skill in asthmatic preschool children's caregivers. METHODS:The caregivers of 12-month-old to 72-month-o...

journal_title：International forum of allergy & rhinology

authors： Topal E,Celiksoy MH,Catal F,Sinanoglu MS,Karakoc HT,Sancak R,Ozturk F

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Increased frequency of migraine was reported in adults with allergic rhinitis (AR). Although migraine is less common in children than in adults, it can begin in early childhood and persist into adulthood. We conducted this population-based cohort study to investigate the incidence and subsequent risk of migr...

journal_title：International forum of allergy & rhinology

authors： Wang IC,Tsai JD,Lin CL,Shen TC,Li TC,Wei CC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Allergy-related illness impacts millions of individuals worldwide. Our objectives were to characterize current trends of clinical trials research relating to allergen immunotherapy and to describe the landscape of allergen immunotherapy in National Institutes of Health (NIH)-supported research inquiry. METH...

journal_title：International forum of allergy & rhinology

authors： Ramsey T,Lai W,Svider PF,Hojjat H,Eloy JA,Folbe AJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Inflammatory profiles for patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) vary between North American and Asian populations. An elevated ethmoid-to-maxillary (E/M) opacification ratio on preoperative imaging is associated with certain postoperative outcomes in Asian populations and populat...

journal_title：International forum of allergy & rhinology

authors： Beswick DM,Smith TL,Mace JC,Alt JA,Farrell NF,Ramakrishnan VR,Schlosser RJ,Soler ZM

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to identify and evaluate adverse clinical outcomes following office-based sclerotherapy using sodium tetradecyl sulfate (STS) for epistaxis due to hereditary hemorrhagic telangiectasias (HHT or Osler-Weber-Rendu). METHODS:A retrospective chart review of 36 adult patients treated wi...

journal_title：International forum of allergy & rhinology

authors： Hanks JE,Hunter D,Goding GS Jr,Boyer HC

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a complex chronic inflammatory disease of the nasal mucosa, caused by an interaction between genetic and environmental factors. As evidence suggests that some genetic variants may increase susceptibility to both AR and asthma, the objective of this study was to identify asthma susce...

journal_title：International forum of allergy & rhinology

authors： Zhao Y,Zhang Y,Zhang L

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:This study reviews the published literature related to extramedullary sinonasal plasmacytomas. Clinical presentation, demographics, treatment, and outcomes of this uncommon disease are reported. METHODS:A systematic review of studies for sinonasal plasmacytomas from 1950 to 2012 was conducted. A PubMed data...

journal_title：International forum of allergy & rhinology

authors： D'Aguillo C,Soni RS,Gordhan C,Liu JK,Baredes S,Eloy JA

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:In this prospective, multicenter, randomized, controlled, double-blind study, we investigated the impact of a mobile patient engagement application on health outcomes and quality of life in allergic rhinitis (AR) and asthma patients. METHODS:In total, 327 patients with diagnoses of persistent AR or mild-to-...

journal_title：International forum of allergy & rhinology

authors： Cingi C,Yorgancioglu A,Cingi CC,Oguzulgen K,Muluk NB,Ulusoy S,Orhon N,Yumru C,Gokdag D,Karakaya G,Çelebi Ş,Çobanoglu HB,Unlu H,Aksoy MA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Treatment of recalcitrant chronic rhinosinusitis (CRS) is a challenge with increasing antibiotic resistance, leading to re-emergence of topical therapies. The aim of this study was to assess safety and efficacy of topical colloidal silver solution for the treatment of Staphylococcus aureus biofilms in a shee...

journal_title：International forum of allergy & rhinology

authors： Rajiv S,Drilling A,Bassiouni A,James C,Vreugde S,Wormald PJ

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Osteitis is a feature of chronic rhinosinusitis (CRS) and often associated with recalcitrant disease. Radiological characteristics of osteitic sinus changes are commonly reported in practice but the clinical and pathologic significance is poorly defined. The objective of this study was to correlate the Kenne...

journal_title：International forum of allergy & rhinology

authors： Snidvongs K,McLachlan R,Sacks R,Earls P,Harvey RJ

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Oncocytomas and oncocytic carcinomas are rare tumors of the sinonasal cavity with the propensity for local invasion. This report and systematic review details a case of a nasal oncocytoma involving the lacrimal sac and provides an update of the current literature. METHODS:A systematic literature review was ...

journal_title：International forum of allergy & rhinology

authors： Hodzic Z,Rowan NR,Kashiwazaki R,Willson TJ,Wang EW,Lee SE

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Staphylococcus aureus infection is known to play a role in recalcitrant chronic rhinosinusitis (CRS). However, it is unknown if recurrent S. aureus infections are caused by the same strain or are due to independent acquisitions of different strains. METHODS:Samples were collected from patients with CRS from...

journal_title：International forum of allergy & rhinology

authors： Drilling A,Coombs GW,Tan HL,Pearson JC,Boase S,Psaltis A,Speck P,Vreugde S,Wormald PJ

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Patient compliance is critical for successful allergen immunotherapy (AIT). Previous studies suggest that AIT compliance is worse outside of controlled clinical trials, with reported subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) noncompliance at 11% to 50% and 3% to 25%, respectively....

journal_title：International forum of allergy & rhinology

authors： Leader BA,Rotella M,Stillman L,DelGaudio JM,Patel ZM,Wise SK

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The effects of desloratadine-montelukast combination on quality of life (QoL) and nasal airflow of patients with perennial allergic rhinitis (PAR) has not been reported. The objective of this work was investigate the efficacy of desloratadine-montelukast combination on nasal obstruction and health-related qu...

journal_title：International forum of allergy & rhinology

authors： Cingi C,Oghan F,Eskiizmir G,Yaz A,Ural A,Erdogmus N

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Variants of squamous cell carcinoma (SCC) make up 15% of all cases of SCC of the upper aerodigestive tract. There are 5 main histologic variants of SCC in the head and neck region: verrucous (VSCC), papillary (PSCC), spindle cell (sarcomatoid) (SCSC), basaloid (BSCC), and adenosquamous (ASC). Conventional si...

journal_title：International forum of allergy & rhinology

authors： Vazquez A,Khan MN,Blake DM,Patel TD,Baredes S,Eloy JA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The etiology of the intense inflammatory response showed by patients with allergic fungal rhinosinusitis (AFRS) remains a mystery. Potential sources of this inflammation may include fungal proteases. Protease-activated receptors (PARs) are components of the innate immune response that are modulated by proteo...

journal_title：International forum of allergy & rhinology

authors： Ebert CS Jr,McKinney KA,Urrutia G,Wu M,Rose AS,Fleischman GM,Thorp B,Senior BA,Zanation AM

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Subcutaneous immunotherapy (SCIT) demands a significant time commitment on the part of the patient, especially during the escalation period when weekly visits are required. Many patients refuse or discontinue treatment in spite of the demonstrated clinical efficacy of SCIT. Understanding the factors that aff...

journal_title：International forum of allergy & rhinology

authors： Jourdy DN,Reisacher WR

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The relationship between olfactory function, rhinencephalon and forebrain changes in Kallmann syndrome (KS) have not been adequately investigated. We evaluated a large cohort of male KS patients using Sniffin' Sticks and MRI in order to study olfactory bulb (OB) volume, olfactory sulcus (OS) depth, cortical ...

journal_title：International forum of allergy & rhinology

authors： Ottaviano G,Cantone E,D'Errico A,Salvalaggio A,Citton V,Scarpa B,Favaro A,Sinisi AA,Liuzzi R,Bonanni G,Di Salle F,Elefante A,Manara R,Staffieri A,Martini A,Brunetti A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Eosinophilic chronic rhinosinusitis (ECRS) is a disease characterized by eosinophilic inflammatory infiltrate and a local type 2 cytokine milieu. Current animal models fail to recapitulate many of the innate and adaptive immunologic hallmarks of the disease, thus hindering the development of effective therap...

journal_title：International forum of allergy & rhinology

authors： Tharakan A,Dobzanski A,London NR Jr,Khalil SM,Surya N,Lane AP,Ramanathan M Jr

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is released in the airway as a critical component of innate immune defense against invading pathogenic organisms. It is well documented that bacteriostatic and bactericidal effects of NO are concentration-dependent. However, few data exist comparing relative susceptibility of common pathoge...

journal_title：International forum of allergy & rhinology

authors： Workman AD,Carey RM,Kohanski MA,Kennedy DW,Palmer JN,Adappa ND,Cohen NA

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Little is known about the use of allergy and asthma medications in older adults. This study aimed to assess the prevalence of use of these medications in older adults and evaluate predictors of their use. METHODS:Cross-sectional study using data from the National Social Life, Health, and Aging Project (NSHA...

journal_title：International forum of allergy & rhinology

authors： Ajmani GS,Wroblewski KE,Baroody FM,Naclerio RM,Pinto JM

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Techniques for inferior turbinate reduction vary from complete turbinectomy to limited cauterization. Surgical methods differ on the degree of tissue reduction and reliance on surgical tissue removal vs tissue ablation. The outcome and morbidity from 3 different turbinate techniques are compared. METHODS:A ...

journal_title：International forum of allergy & rhinology

authors： Barham HP,Thornton MA,Knisely A,Marcells GN,Harvey RJ,Sacks R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Inverted papilloma is a benign sinonasal tumor that arises from a localized attachment site. These attachment sites, however, have not been fully characterized in the literature. The objective of this research was to determine the specific distribution of attachment sites in patients with sinonasal papilloma...

journal_title：International forum of allergy & rhinology

authors： Schneyer MS,Milam BM,Payne SC

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Lumbar drain (LD) use in the management of cerebrospinal fluid (CSF) rhinorrhea remains controversial. We analyzed the relationship between LD placement and CSF leak recurrence after endoscopic repair. METHODS:A retrospective case series was conducted. Patients who underwent CSF leak repair from 1999 to 201...

journal_title：International forum of allergy & rhinology

authors： Caballero N,Bhalla V,Stankiewicz JA,Welch KC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Endoscopic sinus surgery (ESS) enjoys high success rates, but repopulation with pathogenic bacteria is 1 of the hallmarks of poorer outcomes. There are many hypothesized sources of repopulating bacteria; however, this process remains largely unexplored. This study examined changes in the sinus microbiome aft...

journal_title：International forum of allergy & rhinology

authors： Hauser LJ,Ir D,Kingdom TT,Robertson CE,Frank DN,Ramakrishnan VR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Nasal polyposis is characterized by persistent inflammation but the pathogenesis is complex and still debatable. Autophagy has been associated with many human health problems including chronic inflammatory airway diseases. Whether autophagy plays a role in nasal polyps and could be a therapeutic target is co...

journal_title：International forum of allergy & rhinology

authors： Chen JY,Hour TC,Yang SF,Chien CY,Chen HR,Tsai KL,Ko JY,Wang LF

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Patients with chronic rhinosinusitis (CRS) exhibit centrally mediated behavioral changes commonly referred to as "sickness behavior." Sleep alteration is a component of sickness behavior which is estimated to affect up to 70 million patients annually. Patients with CRS have poor sleep quality, and little is ...

journal_title：International forum of allergy & rhinology

authors： Alt JA,Smith TL

更新日期：2013-11-01 00:00:00