Size of septectomy does not affect distribution of nasal irrigation after endoscopic modified Lothrop procedure.

Abstract:

BACKGROUND:The endoscopic modified Lothrop procedure (EMLP) is commonly performed in recalcitrant frontal sinusitis, in part to achieve better penetration of medicated irrigations postoperatively. Although EMLP requires a septectomy for exposure, it is unknown whether septectomy size affects delivery of irrigations. In this study we evaluated the role of septectomy in delivery of irrigations to the EMLP cavity. METHODS:EMLP was performed on fresh human cadavers with sequentially increasing septectomy (minimal septectomy: drilling across septum to combine frontal sinuses; standard septectomy: 1.5 cm anterior to middle turbinate and inferiorly to the midlevel of the turbinate; large septectomy: extension to nasal floor). Irrigation with fluorescein-labeled water was performed with a 240-mL irrigation bottle in the vertex position and recorded with a 30° endoscope fixed in a 4-mm trephine in the paramedian EMLP cavity. Two blinded reviewers scored irrigation distribution recordings (0 = nasal cavity only; 1 = frontal recess; 2 = medial distribution; 3 = lateral distribution; 4 = entire sinus lavage). Distribution scores were assessed with Wilcoxon rank sum analysis. RESULTS:Six specimens (mean age, 75.2 ± 2.4; 50% female) were assessed. Interobserver scores were highly concordant (Kendall's W = 0.86, p < 0.01), internally validating the experiment. Distribution scores did not vary significantly when comparing minimal septectomy with standard or large septectomy (Z = 0.55, p = 0.58, Z = 0.37, p = 0.71). CONCLUSION:Increasing septectomy does not improve irrigation delivery in patients undergoing EMLP. These results suggest that a limited septectomy for access to the bilateral frontal sinuses is all that is required for effective drug delivery postoperatively. This strategy may reduce morbidity associated with larger septectomies.

authors

Roxbury CR,Tang D,Shah J,McBride J,Woodard TD,Sindwani R

doi

10.1002/alr.22158

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

1127-1131

issue

10

eissn

2042-6976

issn

2042-6984

journal_volume

8

pub_type

杂志文章
  • Predictors of 30-day morbidity and mortality in transnasal microscopic pituitary tumor excision.

    abstract:BACKGROUND:There is a lack of population-based, multi-institutional analyses of factors associated with morbidity and mortality following pituitary tumor excision. METHODS:The American College of Surgeons National Surgical Quality Improvement Project files were used to compile information on patients that had undergon...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21641

    authors: Lawrence LA,Baker AB,Nguyen SA,Karnezis TT,Soler ZM,Schlosser RJ

    更新日期:2016-02-01 00:00:00

  • Immunotherapy compliance: comparison of subcutaneous versus sublingual immunotherapy.

    abstract:BACKGROUND:Patient compliance is critical for successful allergen immunotherapy (AIT). Previous studies suggest that AIT compliance is worse outside of controlled clinical trials, with reported subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) noncompliance at 11% to 50% and 3% to 25%, respectively....

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21699

    authors: Leader BA,Rotella M,Stillman L,DelGaudio JM,Patel ZM,Wise SK

    更新日期:2016-05-01 00:00:00

  • Microwave ablation for the treatment of arterial epistaxis: "how I do it".

    abstract:BACKGROUND:Arterial epistaxis is commonly seen in the rhinology clinic and can have a significant impact on quality of life. Previous studies have explored various therapies to address epistaxis. METHODS:Patients were treated in the outpatient clinic or operating room by microwave ablation (MWA) with a 2450-MHz cooled...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22304

    authors: Lou ZC,Dong Y,Lou ZH

    更新日期:2019-06-01 00:00:00

  • Factors impacting revision surgery in patients with chronic rhinosinusitis with nasal polyposis.

    abstract:BACKGROUND:Surgical treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) has evolved over the last decade as rhinologists have increasingly used topical steroid therapies and altered surgical techniques. It is important to understand the changes in success rates of surgery and frequency of revision endosco...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22505

    authors: Loftus CA,Soler ZM,Desiato VM,Koochakzadeh S,Yoo F,Storck KA,Schlosser RJ

    更新日期:2020-03-01 00:00:00

  • Nonsteroidal anti-inflammatory drugs-exacerbated respiratory disease in adolescents.

    abstract:BACKGROUND:There has been no study investigating nonsteroidal anti-inflammatory drugs (NSAIDs)-exacerbated respiratory disease (NERD) exclusively in childhood. Therefore, in the current study, the authors aimed to evaluate the diagnostic features, clinical characteristics, and follow-up of adolescents diagnosed with NE...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21494

    authors: Ertoy Karagol HI,Yilmaz O,Topal E,Ceylan A,Bakirtas A

    更新日期:2015-05-01 00:00:00

  • Office-based olfactory mucosa biopsies.

    abstract:BACKGROUND:Requests from researchers for olfactory mucosal biopsies are increasing as a result of advances in the fields of neuroscience and stem cell biology. Published studies report variable rates of success in obtaining true olfactory tissue, often below 50%. In cases where biopsies are not obtained carefully and c...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21711

    authors: Holbrook EH,Rebeiz L,Schwob JE

    更新日期:2016-06-01 00:00:00

  • Characterization of immunoglobulin E plasma cells that are elevated in the upper airway mucosa of nonatopic patients with chronic rhinosinusitis without nasal polyps.

    abstract:BACKGROUND:The immunologic mechanisms driving inflammation in the upper airways of patients with chronic rhinosinusitis (CRS) are poorly understood. Previous studies have shown that B cells and immunoglobulin E (IgE) levels are elevated in the nasal tissue of patients with atopic chronic rhinosinusitis without nasal po...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21696

    authors: Rashan AR,Goshn E,Peterson A,Yang Y,Phillips M,Sahaf B,Herzenberg L,Nayak JV

    更新日期:2016-04-01 00:00:00

  • Effect of lumbar drain placement on recurrence of cerebrospinal rhinorrhea after endoscopic repair.

    abstract:BACKGROUND:Lumbar drain (LD) use in the management of cerebrospinal fluid (CSF) rhinorrhea remains controversial. We analyzed the relationship between LD placement and CSF leak recurrence after endoscopic repair. METHODS:A retrospective case series was conducted. Patients who underwent CSF leak repair from 1999 to 201...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21023

    authors: Caballero N,Bhalla V,Stankiewicz JA,Welch KC

    更新日期:2012-05-01 00:00:00

  • Chronic rhinosinusitis and sleep: a contemporary review.

    abstract:BACKGROUND:Patients with chronic rhinosinusitis (CRS) exhibit centrally mediated behavioral changes commonly referred to as "sickness behavior." Sleep alteration is a component of sickness behavior which is estimated to affect up to 70 million patients annually. Patients with CRS have poor sleep quality, and little is ...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,评审

    doi:10.1002/alr.21217

    authors: Alt JA,Smith TL

    更新日期:2013-11-01 00:00:00

  • Ossifying fibroma of the nose and paranasal sinuses.

    abstract:BACKGROUND:The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants. METHODS:A search of the U.S. National Library of Medicine (PubMed) database was performed for th...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,评审

    doi:10.1002/alr.21067

    authors: Manes RP,Ryan MW,Batra PS,Mendelsohn D,Fang YV,Marple BF

    更新日期:2013-02-01 00:00:00

  • Impact of mentoring medical students on scholarly productivity.

    abstract:BACKGROUND:Our objectives were to evaluate collaboration with medical students and other nondoctoral authors, and assess whether mentoring such students influences the academic productivity of senior authors. METHODS:Six issues of the Laryngoscope and International Forum of Allergy & Rhinology (IFAR) were examined for...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21247

    authors: Svider PF,Husain Q,Mauro KM,Folbe AJ,Baredes S,Eloy JA

    更新日期:2014-02-01 00:00:00

  • What rhinologists and allergists should know about the medico-legal implications of antibiotic use: a review of the literature.

    abstract:BACKGROUND:Antibiotics are commonly used in the management of both acute rhinosinusitis and acute exacerbations of chronic rhinosinusitis. With their common use, they have become the leading medication for litigation. It is crucial for the provider to be familiar with potential complications and the medico-legal ramifi...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,评审

    doi:10.1002/alr.21433

    authors: Poetker DM,Smith TL

    更新日期:2015-02-01 00:00:00

  • Evaluation of the olfactory bulb volume and olfactory threshold in patients with nasal polyps and impact of functional endoscopic sinus surgery: a longitudinal study.

    abstract:BACKGROUND:Debate still persists on the relation between olfactory bulb volume (OBV) and olfactory function. Many studies suggest that olfactory deprivation decreases the OBV. The aim of this study was to compare the olfactory threshold and OBV of patients with nasal polyps to healthy individuals and to evaluate the im...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21478

    authors: Sadeghi M,Amali A,Ezabadi SR,Motiee-Langroudi M,Farshchi S,Mokhtari Z

    更新日期:2015-04-01 00:00:00

  • The impact of culturable bacterial community on histopathology in chronic rhinosinusitis.

    abstract:BACKGROUND:The influence of the microbial community on inflammatory subtype in chronic rhinosinusitis (CRS) has been proposed. Superantigen mechanisms potentially create a T helper 2 (Th-2)/eosinophilic dominated inflammation as a product of local flora rather than an intrinsic mucosal process. The associations between...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21220

    authors: Rom D,Snidvongs K,Sacks PL,Dalgorf D,Pratt E,Earls P,Sacks R,Harvey RJ

    更新日期:2014-01-01 00:00:00

  • Antibacterial properties of additives used in injection immunotherapy.

    abstract:BACKGROUND:Previous studies have reviewed the safety of preparing and administering allergy injection immunotherapy in a physician's office, and showed no evidence of infectious complications. The current study examines the antimicrobial properties of the common additives used in preparation of multidose immunotherapy ...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.20105

    authors: Gilbert KC,Sundareshan V,Bass RM,Lin SY

    更新日期:2012-03-01 00:00:00

  • Superior turbinate management and olfactory outcome after endoscopic endonasal transsphenoidal surgery for pituitary adenoma: a propensity score-matched cohort study.

    abstract:BACKGROUND:Surgical management of the superior turbinate (ST) is required to access the sella in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary adenoma. Two common ST management techniques include partial resection of the ST (PRST) and intentional lateralization of the ST (ILST). Given the concentrat...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22694

    authors: Li P,Luo K,Zhang Q,Wang Z

    更新日期:2020-12-01 00:00:00

  • Influence of a medialized middle turbinate on olfactory function: a prospective randomized double-blind study.

    abstract:BACKGROUND:Medialization of the middle turbinate (MT) is an effective technique to prevent recurrent rhinosinusitis but could, in theory, reduce olfactory function by interfering the odorants to reach the olfactory mucosae. We performed a prospective randomized double-blind trial under the hypothesis that olfactory fun...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/alr.22279

    authors: Kim SW,Kim RB,Kang H,Cho HJ,Joo YH,Jeon YJ,Jeon SY

    更新日期:2019-05-01 00:00:00

  • The bacteriology of chronic rhinosinusitis and the pre-eminence of Staphylococcus aureus in revision patients.

    abstract:BACKGROUND:The role of bacteria in the etiopathogenesis of chronic rhinosinusitis (CRS) remains an area of interest. The impact of surgery and factors such as the presence of polyps, asthma, and aspirin sensitivity on the bacterial state are poorly understood. To determine the effect of these factors, this study examin...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21159

    authors: Cleland EJ,Bassiouni A,Wormald PJ

    更新日期:2013-08-01 00:00:00

  • Perioperative management in endoscopic endonasal skull-base surgery: a survey of the North American Skull Base Society.

    abstract:BACKGROUND:The objective of this work was to better understand variations in perioperative management in endoscopic endonasal skull-base surgery (EESBS) and to identify trends in management based upon the practice patterns of North American Skull Base Society (NASBS) members. METHODS:A 29-question survey evaluating pe...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22066

    authors: Roxbury CR,Lobo BC,Kshettry VR,D'Anza B,Woodard TD,Recinos PF,Snyderman CH,Sindwani R

    更新日期:2018-05-01 00:00:00

  • Changing paradigms in frontal sinus cerebrospinal fluid leak repair.

    abstract:BACKGROUND:Frontal sinus cerebrospinal fluid (CSF) leaks have traditionally been repaired via open procedures (eg, osteoplastic flap or cranialization). Advancements in instrumentation, technique, and experience have improved the feasibility of repairing frontal sinus skull-base defects using an endoscopic approach. Th...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21019

    authors: Jones V,Virgin F,Riley K,Woodworth BA

    更新日期:2012-05-01 00:00:00

  • Human papillomavirus infection and biomarkers in sinonasal inverted papillomas: clinical significance and molecular mechanisms.

    abstract:BACKGROUND:The role of human papillomavirus (HPV) in sinonasal inverted papillomas (IPs) is controversial. Determining the prevalence of HPV infection and its impact on the molecular biology of these tumors is critical to characterizing its role in the pathogenesis of IPs. METHODS:A total of 112 paraffin-embedded IPs ...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21524

    authors: Scheel A,Lin GC,McHugh JB,Komarck CM,Walline HM,Prince ME,Zacharek MA,Carey TE

    更新日期:2015-08-01 00:00:00

  • Olfactory loss in chronic rhinosinusitis is associated with neuronal activation of c-Jun N-terminal kinase.

    abstract:BACKGROUND:Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. The principal signaling molecules involved in the apoptotic pathway are c-Jun N-terminal kinases (JNK). Although the JNK pathway has emerged as a key player in progra...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22053

    authors: Victores AJ,Chen M,Smith A,Lane AP

    更新日期:2018-03-01 00:00:00

  • The "physician on call patient engagement trial" (POPET): measuring the impact of a mobile patient engagement application on health outcomes and quality of life in allergic rhinitis and asthma patients.

    abstract:BACKGROUND:In this prospective, multicenter, randomized, controlled, double-blind study, we investigated the impact of a mobile patient engagement application on health outcomes and quality of life in allergic rhinitis (AR) and asthma patients. METHODS:In total, 327 patients with diagnoses of persistent AR or mild-to-...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/alr.21468

    authors: Cingi C,Yorgancioglu A,Cingi CC,Oguzulgen K,Muluk NB,Ulusoy S,Orhon N,Yumru C,Gokdag D,Karakaya G,Çelebi Ş,Çobanoglu HB,Unlu H,Aksoy MA

    更新日期:2015-06-01 00:00:00

  • Does bilateral inferior turbinate reduction affect long-term quality-of-life outcomes in patients undergoing endoscopic sinus surgery?

    abstract:BACKGROUND:The objective of this study was to evaluate the impact of bilateral inferior turbinate reduction (BITR) on patient-reported quality of life (QOL) following endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). METHODS:This was a prospective cohort study. Patients with CRS, who were recruited from...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22300

    authors: Scangas GA,Bleier BS,Husain Q,Holbrook EH,Gray ST,Metson R

    更新日期:2019-06-01 00:00:00

  • Asthma treatments: new and emerging therapies.

    abstract:BACKGROUND:As part of this primer, this article is intended to introduce new and emerging therapies for treating asthma. METHODS:A PubMed search was performed for the years 2013 through 2015 for asthma review, asthma treatment, asthma therapy, and asthma new. Subset searches were additionally performed as suggested by...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,评审

    doi:10.1002/alr.21611

    authors: Calhoun KH

    更新日期:2015-09-01 00:00:00

  • Chronic rhinosinusitis precipitated by tumor necrosis factor alpha inhibitors is the phenotype of chronic rhinosinusitis without nasal polyps.

    abstract:BACKGROUND:Chronic rhinosinusitis (CRS) is a frequently observed condition in patients with immunodeficiency secondary to tumor necrosis factor alpha inhibitors (TNFαis). The histologic features of CRS caused by TNFαis have yet to be determined and may have important implications in understanding the pathophysiology of...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.22462

    authors: Papagiannopoulos P,Devins K,Tong CCL,Yver C,Patel NN,Kuhar HN,Bosso JV,Kohanski MA,Tajudeen BA,Kuan EC,Batra PS,Cohen NA,Kennedy DW,Palmer JN,Montone K,Adappa ND

    更新日期:2020-01-01 00:00:00

  • A primer on viral-associated olfactory loss in the era of COVID-19.

    abstract::Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as coronavirus disease 2019 (COVID-19). The possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might cause olfactory dysfunction is certainly plausible. Patients presenting to specialized ...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,评审

    doi:10.1002/alr.22578

    authors: Soler ZM,Patel ZM,Turner JH,Holbrook EH

    更新日期:2020-07-01 00:00:00

  • Complications from office sclerotherapy for epistaxis due to hereditary hemorrhagic telangiectasia (HHT or Osler-Weber-Rendu).

    abstract:BACKGROUND:The aim of this study was to identify and evaluate adverse clinical outcomes following office-based sclerotherapy using sodium tetradecyl sulfate (STS) for epistaxis due to hereditary hemorrhagic telangiectasias (HHT or Osler-Weber-Rendu). METHODS:A retrospective chart review of 36 adult patients treated wi...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21287

    authors: Hanks JE,Hunter D,Goding GS Jr,Boyer HC

    更新日期:2014-05-01 00:00:00

  • Chronic rhinosinusitis without nasal polyps is associated with increased expression of trefoil factor family peptides.

    abstract:BACKGROUND:Trefoil factor family (TFF) peptides are mucin-associated secretory products that are produced in the airways and gastrointestinal tract. These peptides appear to play an important role in mucosal healing and epithelial protection and are overexpressed in chronically inflamed gastrointestinal tissues. We hyp...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章

    doi:10.1002/alr.21334

    authors: Li P,Turner JH

    更新日期:2014-07-01 00:00:00

  • Long-term outcomes in medial flap inferior turbinoplasty are superior to submucosal electrocautery and submucosal powered turbinate reduction.

    abstract:BACKGROUND:Techniques for inferior turbinate reduction vary from complete turbinectomy to limited cauterization. Surgical methods differ on the degree of tissue reduction and reliance on surgical tissue removal vs tissue ablation. The outcome and morbidity from 3 different turbinate techniques are compared. METHODS:A ...

    journal_title:International forum of allergy & rhinology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/alr.21574

    authors: Barham HP,Thornton MA,Knisely A,Marcells GN,Harvey RJ,Sacks R

    更新日期:2016-02-01 00:00:00