CD8A gene polymorphisms predict severity factors in chronic rhinosinusitis.

abstract：BACKGROUND:Odontogenic sinusitis (OS) presents a therapeutic dilemma. Evidence is lacking whether dental treatment alone is sufficient or whether patients will eventually require endoscopic sinus surgery (ESS). Our aim was to identify predictors of OS patients undergoing ESS. METHODS:Retrospective review performed of ...

journal_title：International forum of allergy & rhinology

authors： Mattos JL,Ferguson BJ,Lee S

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-33 plays an important role in controlling immune responses in barrier tissues, and is a potent mediator of inflammatory diseases such as asthma, rheumatoid disease, and chronic rhinosinusitis. The aims of the present study were 2-fold: (1) to determine the stimulatory effect of tumor necrosi...

journal_title：International forum of allergy & rhinology

authors： Park IH,Park JH,Shin JM,Lee HM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Patients with eosinophilic chronic rhinosinusitis (ECRS) have been shown to have greater disease severity and poorer treatment outcomes after sinus surgery. Although the inflammatory pattern of ECRS is essential to diagnosing this subtype, there is currently no consensus for diagnosis. Our aim in this study ...

journal_title：International forum of allergy & rhinology

authors： McHugh T,Snidvongs K,Xie M,Banglawala S,Sommer D

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Little is known about the use of allergy and asthma medications in older adults. This study aimed to assess the prevalence of use of these medications in older adults and evaluate predictors of their use. METHODS:Cross-sectional study using data from the National Social Life, Health, and Aging Project (NSHA...

journal_title：International forum of allergy & rhinology

authors： Ajmani GS,Wroblewski KE,Baroody FM,Naclerio RM,Pinto JM

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Previous studies have consistently shown that females with chronic rhinosinusitis (CRS) have a greater CRS symptom burden than males with CRS. Our objective was to determine whether differential disease perception could explain this phenomenon. METHODS:A total of 500 participants (239 males, 261 females) wi...

journal_title：International forum of allergy & rhinology

authors： Phillips KM,Bergmark RW,Hoehle LP,Shu ET,Caradonna DS,Gray ST,Sedaghat AR

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Endoscopic repair of anterior skull-base defects has become the gold standard for management of cerebrospinal fluid (CSF) rhinorrhea. Both improved techniques and adjuvant therapies have led to accepted success rates of greater than 90%. As management has evolved, shorter hospitalizations have been required ...

journal_title：International forum of allergy & rhinology

authors： Adams AS,Francis DO,Russell PT

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Olfaction is one of the important senses for humans. Systemic glucocorticoids are the most commonly used medications for olfactory loss because of their strong anti-inflammatory effects. However, their effect on olfactory function is still controversial and the precise mechanism is not clear. To gain a globa...

journal_title：International forum of allergy & rhinology

authors： Tian J,Pinto JM,Xin Y,Zhang H,Li L,Sun Z,Wei Y

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Insufficiency of the nasal valve is increasingly being recognized as a cause of nasal airway obstruction. The condition is associated with many symptoms, including nasal congestion, sleep disturbance, snoring, and an overall decline in quality of life (QoL). An in-office, minimally invasive radiofrequency tr...

journal_title：International forum of allergy & rhinology

authors： Ephrat M,Jacobowitz O,Driver M

更新日期：2020-08-09 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis with nasal polyps (CRSwNP) is prolonged inflammation of the sinonasal mucosa. Interleukin-32 (IL-32) is involved in the pathogenesis of chronic lung inflammatory diseases. The aim of study is to compare the expression level of IL-32 in normal nasal mucosa and CRSwNP and to investigate ...

journal_title：International forum of allergy & rhinology

authors： Cho JS,Kim JA,Park JH,Park IH,Han IH,Lee HM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Increased frequency of migraine was reported in adults with allergic rhinitis (AR). Although migraine is less common in children than in adults, it can begin in early childhood and persist into adulthood. We conducted this population-based cohort study to investigate the incidence and subsequent risk of migr...

journal_title：International forum of allergy & rhinology

authors： Wang IC,Tsai JD,Lin CL,Shen TC,Li TC,Wei CC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The pathogenic roles of fungus and bacteria in chronic rhinosinusitis (CRS) remain unclear. Recently, we described the bacterial ball, which is distinct from the fungus ball, as an unusual phenotype of bacterial infection. In this study, we investigated the clinical, histopathologic, and immunologic characte...

journal_title：International forum of allergy & rhinology

authors： Kim DK,Wi YC,Shin SJ,Kim KR,Kim DW,Cho SH

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Frontal sinus cerebrospinal fluid (CSF) leaks have traditionally been repaired via open procedures (eg, osteoplastic flap or cranialization). Advancements in instrumentation, technique, and experience have improved the feasibility of repairing frontal sinus skull-base defects using an endoscopic approach. Th...

journal_title：International forum of allergy & rhinology

authors： Jones V,Virgin F,Riley K,Woodworth BA

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The objective of this work was to evaluate prevalence of eosinophilic esophagitis (EoE) in the United States, and analyze prevalence of atopic disease in patients with EoE. The study design was a retrospective administrative database analysis in U.S.-based outpatient settings. METHODS:A retrospective claims...

journal_title：International forum of allergy & rhinology

authors： Benninger MS,Strohl M,Holy CE,Hanick AL,Bryson PC

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Although nasal congestion is among the most common symptoms in subjects suffering from nasal diseases, relatively few data on normal airflow resistance are available for reference, especially in healthy Chinese subjects. The aim of present study was therefore to objectively measure the normal airflow resista...

journal_title：International forum of allergy & rhinology

authors： Ren L,Zhang L,Duan S,Zhang W,Zhang Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Chronic sphenoid rhinosinusitis (CSR) refractory to both medical management and 1 or more sphenoidotomies is a difficult entity to treat. In contrast to the surgical hierarchy that exists for the frontal sinus, there is no systematic approach for addressing persistent disease in the sphenoid. Sphenoid marsup...

journal_title：International forum of allergy & rhinology

authors： Leight WD,Leopold DA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-9 and IL-17C have been known to play a role in allergic inflammation, yet, their roles in chronic rhinosinusitis (CRS) are not well defined. IL-9 induces changes in epithelial cell gene expression leading to goblet cell metaplasia, whereas IL-17C is functionally distinct in that its expressi...

journal_title：International forum of allergy & rhinology

authors： Olcott CM,Han JK,Cunningham TD,Franzese CB

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Anatomic limitations complicate complete eradication of debris from the maxillary sinus using an exclusively transnasal (TN) endoscopic technique. Creation of a canine fossa trephination (CFT) permits a more direct approach than removal via the maxillary ostium. METHODS:Microdebrider eradication of debris co...

journal_title：International forum of allergy & rhinology

authors： Feldt BA,McMains KC,Weitzel EK

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. The principal signaling molecules involved in the apoptotic pathway are c-Jun N-terminal kinases (JNK). Although the JNK pathway has emerged as a key player in progra...

journal_title：International forum of allergy & rhinology

authors： Victores AJ,Chen M,Smith A,Lane AP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The relationship between olfactory function, rhinencephalon and forebrain changes in Kallmann syndrome (KS) have not been adequately investigated. We evaluated a large cohort of male KS patients using Sniffin' Sticks and MRI in order to study olfactory bulb (OB) volume, olfactory sulcus (OS) depth, cortical ...

journal_title：International forum of allergy & rhinology

authors： Ottaviano G,Cantone E,D'Errico A,Salvalaggio A,Citton V,Scarpa B,Favaro A,Sinisi AA,Liuzzi R,Bonanni G,Di Salle F,Elefante A,Manara R,Staffieri A,Martini A,Brunetti A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare 2010 access to, usage of, and attitudes toward image-guided surgery (IGS) for endoscopic sinus surgery and anterior skull-base surgery to those in 2005. METHODS:A mail survey of American Rhinologic Society (ARS) members was performed in January 2010. Results were compare...

journal_title：International forum of allergy & rhinology

authors： Justice JM,Orlandi RR

更新日期：2012-03-01 00:00:00

abstract：:Recent evidence has demonstrated an expanding role of respiratory epithelial cells in immune surveillance and modulation. Studies have been focusing on the earliest events that link epithelial injury to downstream inflammatory responses. Cytokines produced by and released from respiratory epithelial cells are among th...

journal_title：International forum of allergy & rhinology

authors： Patel NN,Kohanski MA,Maina IW,Workman AD,Herbert DR,Cohen NA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The incidence of adverse sequelae related to trauma of cranial nerve V2 (V2) and the Vidian nerve (VN) during endoscopic pterygoid recess repair (PRR) of lateral sphenoid encephalocele is insufficiently reported in the medical literature. As part of our quality assessment and improvement program we sought to...

journal_title：International forum of allergy & rhinology

authors： Chislett SP,Limjuco AP,Solyar AY,Lanza DC

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Little is known regarding the role of the microbiome of the paranasal sinuses and its contribution to sinus mucosal health and disease. Consequently, we examined the microbiome of chronic rhinosinusitis patients with polyps (CRSwNP) and a control population to provide new insights into the microbiota associa...

journal_title：International forum of allergy & rhinology

authors： Gan W,Yang F,Tang Y,Zhou D,Qing D,Hu J,Liu S,Liu F,Meng J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:We recently demonstrated the bitter taste receptor T2R38 upregulates sinonasal mucosal innate defense in response to gram-negative quorum-sensing molecules through increased nitric oxide production and mucociliary clearance. T2R38 was initially identified in the quest to understand the variability in bitter ...

journal_title：International forum of allergy & rhinology

authors： Adappa ND,Howland TJ,Palmer JN,Kennedy DW,Doghramji L,Lysenko A,Reed DR,Lee RJ,Cohen NA

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The endoscopic modified Lothrop procedure (EMLP) is commonly performed in recalcitrant frontal sinusitis, in part to achieve better penetration of medicated irrigations postoperatively. Although EMLP requires a septectomy for exposure, it is unknown whether septectomy size affects delivery of irrigations. In...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Tang D,Shah J,McBride J,Woodard TD,Sindwani R

更新日期：2018-10-01 00:00:00

abstract：:Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as coronavirus disease 2019 (COVID-19). The possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might cause olfactory dysfunction is certainly plausible. Patients presenting to specialized ...

journal_title：International forum of allergy & rhinology

authors： Soler ZM,Patel ZM,Turner JH,Holbrook EH

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The endoscopic modified Lothrop procedure (EMLP) is used to manage ongoing refractory frontal sinusitis after failed previous endoscopic sinus surgery (ESS), but this approach has a significant restenosis rate. We evaluated the potential benefits of mucosal grafts and pedicled flaps on the opening of the new...

journal_title：International forum of allergy & rhinology

authors： Wang YP,Shen PH,Hsieh LC,Wormald PJ

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Endoscopic sinus surgery (ESS) enjoys high success rates, but repopulation with pathogenic bacteria is 1 of the hallmarks of poorer outcomes. There are many hypothesized sources of repopulating bacteria; however, this process remains largely unexplored. This study examined changes in the sinus microbiome aft...

journal_title：International forum of allergy & rhinology

authors： Hauser LJ,Ir D,Kingdom TT,Robertson CE,Frank DN,Ramakrishnan VR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The available allergic rhinitis (AR) literature continues to grow. Critical evaluation and understanding of this literature is important to appropriately utilize this knowledge in the care of AR patients. The International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR) has been pro...

journal_title：International forum of allergy & rhinology

authors： Wise SK,Lin SY,Toskala E

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The objective of this work was to better understand variations in perioperative management in endoscopic endonasal skull-base surgery (EESBS) and to identify trends in management based upon the practice patterns of North American Skull Base Society (NASBS) members. METHODS:A 29-question survey evaluating pe...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Lobo BC,Kshettry VR,D'Anza B,Woodard TD,Recinos PF,Snyderman CH,Sindwani R

更新日期：2018-05-01 00:00:00