Free mucosal grafts and anterior pedicled flaps to prevent ostium restenosis after endoscopic modified Lothrop (frontal drillout) procedure: a randomized, controlled study.

abstract：BACKGROUND:Inadequate efficacy of current intranasal steroids in chronic rhinosinusitis (CRS) is attributable to ineffective and/or inconsistent drug delivery to target anatomic sites. A new exhalation delivery system with fluticasone (EDS-FLU) may improve outcomes by significantly increasing superior/posterior cortico...

journal_title：International forum of allergy & rhinology

authors： Palmer JN,Jacobson KW,Messina JC,Kosik-Gonzalez C,Djupesland PG,Mahmoud RA

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. The principal signaling molecules involved in the apoptotic pathway are c-Jun N-terminal kinases (JNK). Although the JNK pathway has emerged as a key player in progra...

journal_title：International forum of allergy & rhinology

authors： Victores AJ,Chen M,Smith A,Lane AP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Allergy-related illness impacts millions of individuals worldwide. Our objectives were to characterize current trends of clinical trials research relating to allergen immunotherapy and to describe the landscape of allergen immunotherapy in National Institutes of Health (NIH)-supported research inquiry. METH...

journal_title：International forum of allergy & rhinology

authors： Ramsey T,Lai W,Svider PF,Hojjat H,Eloy JA,Folbe AJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Osteitis is a feature of chronic rhinosinusitis (CRS) and often associated with recalcitrant disease. Radiological characteristics of osteitic sinus changes are commonly reported in practice but the clinical and pathologic significance is poorly defined. The objective of this study was to correlate the Kenne...

journal_title：International forum of allergy & rhinology

authors： Snidvongs K,McLachlan R,Sacks R,Earls P,Harvey RJ

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Treatment options for chronic rhinosinusitis with recurrent polyposis (CRSwNP) after endoscopic sinus surgery (ESS) are limited, and include frequent use of systemic steroids and revision surgery. A bioabsorbable, steroid-eluting implant was studied for its ability to dilate sinuses obstructed by polyps and ...

journal_title：International forum of allergy & rhinology

authors： Lavigne F,Miller SK,Gould AR,Lanier BJ,Romett JL

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is released in the airway as a critical component of innate immune defense against invading pathogenic organisms. It is well documented that bacteriostatic and bactericidal effects of NO are concentration-dependent. However, few data exist comparing relative susceptibility of common pathoge...

journal_title：International forum of allergy & rhinology

authors： Workman AD,Carey RM,Kohanski MA,Kennedy DW,Palmer JN,Adappa ND,Cohen NA

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare 2010 access to, usage of, and attitudes toward image-guided surgery (IGS) for endoscopic sinus surgery and anterior skull-base surgery to those in 2005. METHODS:A mail survey of American Rhinologic Society (ARS) members was performed in January 2010. Results were compare...

journal_title：International forum of allergy & rhinology

authors： Justice JM,Orlandi RR

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to compare the absolute breaking strength of various soft tissue skull base (SB) repairs in an in vitro porcine model. METHODS:A burst pressure (BP) testing system was designed using an axial loading force to create increasing hydraulic pressure. Defects measuring 0.5 × 0.5 cm w...

journal_title：International forum of allergy & rhinology

authors： Fandiño M,Macdonald K,Singh D,Whyne C,Witterick I

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Evidence suggests relationships between allergic rhinitis (AR) and poor sleep parameters, but population-based studies in the United States are lacking. This study investigates the relationship between AR and sleep parameters in a representative sample of U.S. adults. METHODS:Cross-sectional study of 5563 p...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Qiu M,Shargorodsky J,Lin SY

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The most dramatic complication in endonasal surgery is inadvertent injury to the internal carotid artery (ICA) with massive bleeding. Nasal packing is the favored technique for control; however, this often causes complete carotid occlusion or carotid stenosis, contributing to the morbidity and mortality of t...

journal_title：International forum of allergy & rhinology

authors： Valentine R,Boase S,Jervis-Bardy J,Dones Cabral JD,Robinson S,Wormald PJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Environmental factors such as inhaled pollutants like cigarette smoke may play a significant role in diseases of the upper airway including chronic rhinosinusitis (CRS). The objectives of this review are to summarize prior studies that describe the correlation between active smoking and secondhand smoke (SHS...

journal_title：International forum of allergy & rhinology

authors： Reh DD,Higgins TS,Smith TL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The incidence of adverse sequelae related to trauma of cranial nerve V2 (V2) and the Vidian nerve (VN) during endoscopic pterygoid recess repair (PRR) of lateral sphenoid encephalocele is insufficiently reported in the medical literature. As part of our quality assessment and improvement program we sought to...

journal_title：International forum of allergy & rhinology

authors： Chislett SP,Limjuco AP,Solyar AY,Lanza DC

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Reported revision rates for endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) vary significantly. Several investigations examining revision rates for ESS have been limited by duration of follow-up, academic centers, or small surgeon cohorts. The objective of this study was to define the long-te...

journal_title：International forum of allergy & rhinology

authors： Smith KA,Orlandi RR,Oakley G,Meeks H,Curtin K,Alt JA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Patients with eosinophilic chronic rhinosinusitis (ECRS) have been shown to have greater disease severity and poorer treatment outcomes after sinus surgery. Although the inflammatory pattern of ECRS is essential to diagnosing this subtype, there is currently no consensus for diagnosis. Our aim in this study ...

journal_title：International forum of allergy & rhinology

authors： McHugh T,Snidvongs K,Xie M,Banglawala S,Sommer D

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The influence of the microbial community on inflammatory subtype in chronic rhinosinusitis (CRS) has been proposed. Superantigen mechanisms potentially create a T helper 2 (Th-2)/eosinophilic dominated inflammation as a product of local flora rather than an intrinsic mucosal process. The associations between...

journal_title：International forum of allergy & rhinology

authors： Rom D,Snidvongs K,Sacks PL,Dalgorf D,Pratt E,Earls P,Sacks R,Harvey RJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is associated with sleep dysfunction, but the underlying pathophysiology is poorly understood. The purpose of this study was to determine if mucosal eosinophilia or neutrophilia were associated with sleep dysfunction severity or altered the improvement in sleep dysfunction follow...

journal_title：International forum of allergy & rhinology

authors： Farrell NF,Mace JC,Sauer DA,Thomas AJ,Geltzeiler M,Detwiller KY,Alt JA,Smith TL

更新日期：2020-08-11 00:00:00

abstract：BACKGROUND:The effects of desloratadine-montelukast combination on quality of life (QoL) and nasal airflow of patients with perennial allergic rhinitis (PAR) has not been reported. The objective of this work was investigate the efficacy of desloratadine-montelukast combination on nasal obstruction and health-related qu...

journal_title：International forum of allergy & rhinology

authors： Cingi C,Oghan F,Eskiizmir G,Yaz A,Ural A,Erdogmus N

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Little is known regarding the role of the microbiome of the paranasal sinuses and its contribution to sinus mucosal health and disease. Consequently, we examined the microbiome of chronic rhinosinusitis patients with polyps (CRSwNP) and a control population to provide new insights into the microbiota associa...

journal_title：International forum of allergy & rhinology

authors： Gan W,Yang F,Tang Y,Zhou D,Qing D,Hu J,Liu S,Liu F,Meng J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Although nasal congestion is among the most common symptoms in subjects suffering from nasal diseases, relatively few data on normal airflow resistance are available for reference, especially in healthy Chinese subjects. The aim of present study was therefore to objectively measure the normal airflow resista...

journal_title：International forum of allergy & rhinology

authors： Ren L,Zhang L,Duan S,Zhang W,Zhang Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Asthma is a chronic inflammatory disease of the lower airway that is commonly encountered by the otolaryngologist. This article provides information on how to recognize patients with asthma and discuss issues related to diagnosis, treatment, and continued management within the context of current guidelines. ...

journal_title：International forum of allergy & rhinology

authors： Reisacher WR

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Sinonasal adenoid cystic carcinoma (SNACC) is a rare malignancy with a propensity for distant metastasis. In this study we describe the incidence and determinants of survival among patients with SNACC between the years 2004 and 2012 using the National Cancer Database (NCDB). METHODS:This was a retrospective...

journal_title：International forum of allergy & rhinology

authors： Trope M,Triantafillou V,Kohanski MA,Kuan EC,Tong CCL,Patel NN,Maina IW,Carey RM,Workman AD,Palmer JN,Adappa ND,Newman JG,Brant JA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Knowledge of our immune system functions is critical for understanding allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies. METHODS:This review explains the current understanding of the basic immunology of the...

journal_title：International forum of allergy & rhinology

authors： Toskala E

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has been defined as inflammation of the paranasal sinuses lasting at least 12 weeks with corresponding 2 or more "cardinal symptoms" that include: (1) nasal obstruction; (2) thick nasal discharge; (3) facial pain/pressure; and (4) reduction or loss of sense of smell. Although pri...

journal_title：International forum of allergy & rhinology

authors： DeConde AS,Mace JC,Alt JA,Soler ZM,Orlandi RR,Smith TL

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Endoscopic sinus surgery (ESS) enjoys high success rates, but repopulation with pathogenic bacteria is 1 of the hallmarks of poorer outcomes. There are many hypothesized sources of repopulating bacteria; however, this process remains largely unexplored. This study examined changes in the sinus microbiome aft...

journal_title：International forum of allergy & rhinology

authors： Hauser LJ,Ir D,Kingdom TT,Robertson CE,Frank DN,Ramakrishnan VR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The objective of this case series was to report what is to the best of our knowledge the first reports of nasopharyngeal and soft palate pseudomeningoceles tracking submucosally from the sphenoid sinus. METHODS:Analysis of cases through medical records. RESULTS:Two cases of middle-aged male patients presen...

journal_title：International forum of allergy & rhinology

authors： Lieberman SM,Ojo RB,Casiano RR

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Nasal polyposis is characterized by persistent inflammation but the pathogenesis is complex and still debatable. Autophagy has been associated with many human health problems including chronic inflammatory airway diseases. Whether autophagy plays a role in nasal polyps and could be a therapeutic target is co...

journal_title：International forum of allergy & rhinology

authors： Chen JY,Hour TC,Yang SF,Chien CY,Chen HR,Tsai KL,Ko JY,Wang LF

更新日期：2015-02-01 00:00:00

abstract：INTRODUCTION:This study describes safety outcomes of pediatric endoscopic sinus surgery (ESS) to identify risk factors for 30-day postoperative adverse events using the National Surgical Quality Improvement Program-Pediatric (NSQIP-P) database. METHODS:We performed a retrospective cohort study involving patients in th...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Li L,Rhee D,Jatana KR,Shah RK,Boss EF

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether anterior rhinoscopy (AR), nasal endoscopy (NE) and paranasal sinus computed tomography (PNS CT) can predict other sinonasal obstructive pathologies in the setting of nasal septal deviation (NSD), and to evaluate the impact of preoperative PNS CT on the decision ...

journal_title：International forum of allergy & rhinology

authors： Günbey E,Günbey HP,Uygun S,Karabulut H,Cingi C

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Inverted papilloma is a benign sinonasal tumor that arises from a localized attachment site. These attachment sites, however, have not been fully characterized in the literature. The objective of this research was to determine the specific distribution of attachment sites in patients with sinonasal papilloma...

journal_title：International forum of allergy & rhinology

authors： Schneyer MS,Milam BM,Payne SC

更新日期：2011-07-01 00:00:00

abstract：:Recent evidence has demonstrated an expanding role of respiratory epithelial cells in immune surveillance and modulation. Studies have been focusing on the earliest events that link epithelial injury to downstream inflammatory responses. Cytokines produced by and released from respiratory epithelial cells are among th...

journal_title：International forum of allergy & rhinology

authors： Patel NN,Kohanski MA,Maina IW,Workman AD,Herbert DR,Cohen NA

更新日期：2019-01-01 00:00:00