Antibacterial properties of additives used in injection immunotherapy.

abstract：BACKGROUND:Antibiotics are commonly used in the management of both acute rhinosinusitis and acute exacerbations of chronic rhinosinusitis. With their common use, they have become the leading medication for litigation. It is crucial for the provider to be familiar with potential complications and the medico-legal ramifi...

journal_title：International forum of allergy & rhinology

authors： Poetker DM,Smith TL

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:According to epidemiologic studies, fine particulate matter (particulate matter ≤2.5 μm, PM2.5) is closely associated with increases in the incidence and severity of chronic rhinosinusitis (CRS). However, the role of PM2.5 in the pathophysiology of CRS remains largely unknown. In this study, we investigated ...

journal_title：International forum of allergy & rhinology

authors： Zhao R,Guo Z,Dong W,Deng C,Han Z,Liu J,Wang H,Zhuang G,Zhang R

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Treatment of recalcitrant chronic rhinosinusitis (CRS) is a challenge with increasing antibiotic resistance, leading to re-emergence of topical therapies. The aim of this study was to assess safety and efficacy of topical colloidal silver solution for the treatment of Staphylococcus aureus biofilms in a shee...

journal_title：International forum of allergy & rhinology

authors： Rajiv S,Drilling A,Bassiouni A,James C,Vreugde S,Wormald PJ

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Sufficient clinical data are not available on the effect of hypothyroidism on olfactory function in adults. In this study, we aimed to evaluate the olfactory function of adult patients diagnosed with primary hypothyroidism. METHODS:Forty-five patients aged between 18 and 60 years who were diagnosed with cli...

journal_title：International forum of allergy & rhinology

authors： Günbey E,Karlı R,Gökosmanoğlu F,Düzgün B,Ayhan E,Atmaca H,Ünal R

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Social determinants of health can have a substantial impact on treatment outcomes. Prior study has shown that socioeconomic status influences the likelihood of improvement in quality-of-life (QOL) following endoscopic sinus surgery (ESS). However, the impact of socioeconomic factors on changes in productivit...

journal_title：International forum of allergy & rhinology

authors： Beswick DM,Mace JC,Soler ZM,Rudmik L,Alt JA,Smith KA,Detwiller KY,Ramakrishnan VR,Smith TL

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-9 and IL-17C have been known to play a role in allergic inflammation, yet, their roles in chronic rhinosinusitis (CRS) are not well defined. IL-9 induces changes in epithelial cell gene expression leading to goblet cell metaplasia, whereas IL-17C is functionally distinct in that its expressi...

journal_title：International forum of allergy & rhinology

authors： Olcott CM,Han JK,Cunningham TD,Franzese CB

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The role of human papillomavirus (HPV) in sinonasal inverted papillomas (IPs) is controversial. Determining the prevalence of HPV infection and its impact on the molecular biology of these tumors is critical to characterizing its role in the pathogenesis of IPs. METHODS:A total of 112 paraffin-embedded IPs ...

journal_title：International forum of allergy & rhinology

authors： Scheel A,Lin GC,McHugh JB,Komarck CM,Walline HM,Prince ME,Zacharek MA,Carey TE

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the pathogenesis of chronic rhinosinusitis (CRS) remains uncertain. Recent evidence suggests that bacteria are able to establish microcolonies within the underlying mucosa. However, to date there has been no systematic comparison of bacterial community composition and diversity in the...

journal_title：International forum of allergy & rhinology

authors： Kim RJ,Biswas K,Hoggard M,Taylor MW,Douglas RG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is one of the most common chronic diseases in childhood, with a current prevalence of 6% to 9%, but a prevalence that is increasing at an alarming rate. Asthma is a complex genetic disorder with strong environmental influence. It imposes a growing burden on our society in terms of morbidity,...

journal_title：International forum of allergy & rhinology

authors： Toskala E,Kennedy DW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Little is known regarding the role of the microbiome of the paranasal sinuses and its contribution to sinus mucosal health and disease. Consequently, we examined the microbiome of chronic rhinosinusitis patients with polyps (CRSwNP) and a control population to provide new insights into the microbiota associa...

journal_title：International forum of allergy & rhinology

authors： Gan W,Yang F,Tang Y,Zhou D,Qing D,Hu J,Liu S,Liu F,Meng J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Odontogenic sinusitis (OS) presents a therapeutic dilemma. Evidence is lacking whether dental treatment alone is sufficient or whether patients will eventually require endoscopic sinus surgery (ESS). Our aim was to identify predictors of OS patients undergoing ESS. METHODS:Retrospective review performed of ...

journal_title：International forum of allergy & rhinology

authors： Mattos JL,Ferguson BJ,Lee S

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Patients with eosinophilic chronic rhinosinusitis (ECRS) have been shown to have greater disease severity and poorer treatment outcomes after sinus surgery. Although the inflammatory pattern of ECRS is essential to diagnosing this subtype, there is currently no consensus for diagnosis. Our aim in this study ...

journal_title：International forum of allergy & rhinology

authors： McHugh T,Snidvongs K,Xie M,Banglawala S,Sommer D

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Sinonasal squamous cell carcinoma (SNSCC) is the most common malignancy of the paranasal sinuses. Surgery is the mainstay of treatment, yet positive surgical margins (PSM) are common and the prognostic impact on overall survival (OS) is mixed. Given the heterogeneity of impact of PSM on OS within the literat...

journal_title：International forum of allergy & rhinology

authors： Jafari A,Shen SA,Qualliotine JR,Orosco RK,Califano JA,DeConde AS

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Spontaneous cerebrospinal fluid (CSF) rhinorrhea has been associated with elevated intracranial pressure (ICP). As such, ICP reducing measures are commonly employed to optimize repair. Although postoperative acetazolamide use has been described, no data currently exists on the potential for preoperative use....

journal_title：International forum of allergy & rhinology

authors： Tilak AM,Koehn H,Mattos J,Payne SC

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Many asthmatic patients have coexisting allergic rhinitis (AR). This study aims to investigate the compliance of physicians with respiratory medicine specialty (PRMs) to Global Initiative for Asthma (GINA) and Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines during the management of their asthma-...

journal_title：International forum of allergy & rhinology

authors： Su N,Lin J,Liu G,Yin K,Zhou X,Shen H,Chen P,Chen R,Liu C,Wu C,Zhao J,Lin Y

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Surgical treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) has evolved over the last decade as rhinologists have increasingly used topical steroid therapies and altered surgical techniques. It is important to understand the changes in success rates of surgery and frequency of revision endosco...

journal_title：International forum of allergy & rhinology

authors： Loftus CA,Soler ZM,Desiato VM,Koochakzadeh S,Yoo F,Storck KA,Schlosser RJ

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Little is known about the use of allergy and asthma medications in older adults. This study aimed to assess the prevalence of use of these medications in older adults and evaluate predictors of their use. METHODS:Cross-sectional study using data from the National Social Life, Health, and Aging Project (NSHA...

journal_title：International forum of allergy & rhinology

authors： Ajmani GS,Wroblewski KE,Baroody FM,Naclerio RM,Pinto JM

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The extracellular matrix (ECM) is a potentially important component of mucosal immunity. ECM dysregulation in chronic rhinosinusitis (CRS) is suggested by genomewide association studies identifying ECM genes as top candidates. Further support is afforded by the demonstration of increased expression of perios...

journal_title：International forum of allergy & rhinology

authors： Zhang W,Hubin G,Endam LM,Al-Mot S,Filali-Mouhim A,Desrosiers M

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to demonstrate how direct electrical stimulation can activate the olfactory bulb after denervation of the olfactory nerve input. METHODS:Sprague-Dawley rats (n = 5) were anesthetized and olfactory bulbs exposed. Olfactory nerves were transected by passing a Teflon blade between the...

journal_title：International forum of allergy & rhinology

authors： Coelho DH,Socolovsky LD,Costanzo RM

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Patients  with  viral respiratory infections/viral rhinitis/common colds are often treated with antibiotic; however, there is little information on whether or how bacterial microbiota in the nose and nasopharynx might influence the course of viral illnesses. METHODS:To initiate investigation of possible int...

journal_title：International forum of allergy & rhinology

authors： Allen EK,Pitkäranta A,Mäki M,Hendley JO,Laakso S,Sale MM,Winther B

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Treatment options for chronic rhinosinusitis with recurrent polyposis (CRSwNP) after endoscopic sinus surgery (ESS) are limited, and include frequent use of systemic steroids and revision surgery. A bioabsorbable, steroid-eluting implant was studied for its ability to dilate sinuses obstructed by polyps and ...

journal_title：International forum of allergy & rhinology

authors： Lavigne F,Miller SK,Gould AR,Lanier BJ,Romett JL

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Environmental factors such as inhaled pollutants like cigarette smoke may play a significant role in diseases of the upper airway including chronic rhinosinusitis (CRS). The objectives of this review are to summarize prior studies that describe the correlation between active smoking and secondhand smoke (SHS...

journal_title：International forum of allergy & rhinology

authors： Reh DD,Higgins TS,Smith TL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Currently, limited literature exists about sinonasal adenoid cystic carcinoma (SNACC). In this study, we analyze the demographics, survival, and treatment efficacy of this rare entity. METHODS:Our study was a retrospective population-based analysis of SNACC in the Surveillance, Epidemiology, and End Results...

journal_title：International forum of allergy & rhinology

authors： Unsal AA,Chung SY,Zhou AH,Baredes S,Eloy JA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The correct use of inhalation devices is essential for successful therapy. We aimed to evaluate the skills in the use of a spacer device with an metered-dose inhaler (MDI) and factors that influence this skill in asthmatic preschool children's caregivers. METHODS:The caregivers of 12-month-old to 72-month-o...

journal_title：International forum of allergy & rhinology

authors： Topal E,Celiksoy MH,Catal F,Sinanoglu MS,Karakoc HT,Sancak R,Ozturk F

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The histological features of osteitis in chronic rhinosinusitis (CRS) in animal studies induced by bacterial inoculation into maxillary sinuses revealed inflammatory involvement of the underlying bone matrix and/or the Haversian system; however, human studies do not mention these findings. The objective of t...

journal_title：International forum of allergy & rhinology

authors： Snidvongs K,Earls P,Dalgorf D,Sacks R,Pratt E,Harvey RJ

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:This analysis explores the increasing heterogeneity of trends in allergy management under the premise that the practice of allergy has undergone significant changes in national economics, healthcare delivery, and treatment options from 2007 to 2016. METHODS:Centers for Medicare and Medicaid Services (CMS) d...

journal_title：International forum of allergy & rhinology

authors： Arianpour K,Svider PF,Yuhan B,Hooda Z,Eloy JA,Folbe AJ

更新日期：2018-05-21 00:00:00

abstract：BACKGROUND:The treatment of the middle turbinate (MT) during endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) remains a contentious issue with arguments both for and against its resection. The purpose of this study was to examine the clinical impact of partial MT resection (PMTR) during ESS, paying parti...

journal_title：International forum of allergy & rhinology

authors： Tan NC,Goggin R,Psaltis AJ,Wormald PJ

更新日期：2018-04-06 00:00:00

abstract：BACKGROUND:Cystic fibrosis (CF) is caused by a misfunctional CF transmembrane conductance regulator (CFTR) protein, which is believed to contributes to the regulation of the airway surface liquid (ASL) pH. This study investigated acid and base secretion in freshly excised human nasal tissues from CF patients homozygous...

journal_title：International forum of allergy & rhinology

authors： Cho DY,Hwang PH,Illek B,Fischer H

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Olfactory dysfunction is 1 of the hallmark symptoms of chronic rhinosinusitis (CRS). Eosinophilic inflammation has been implicated as a potential causative factor. However, prior studies have been limited by retrospective study designs, concomitant use of systemic corticosteroids, and other confounding facto...

journal_title：International forum of allergy & rhinology

authors： Hauser LJ,Chandra RK,Li P,Turner JH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:After endoscopic sinus surgery (ESS), endoscopy is used to gauge surgical success and clinical outcomes. Prior studies have not examined this topic prospectively using validated outcome metrics across multiple institutions. METHODS:A multi-institutional, prospective study of patients with chronic rhinosinus...

journal_title：International forum of allergy & rhinology

authors： Schlosser RJ,Storck K,Smith TL,Mace JC,Rudmik L,Shahangian A,Soler ZM

更新日期：2016-02-01 00:00:00