Abstract:
PURPOSE:There are limited data on the contribution of fortified foods and nutritional supplements to intakes of vitamin D in young children. Our objective was to examine the intake, adequacy, risk of excessive intake and sources of dietary vitamin D. METHODS:The nationally representative cross-sectional dietary survey of young children (aged 1-4 years) (n 500) was used to evaluate vitamin D intake and quantify the contribution of the base diet, fortified foods and nutritional supplements to total intake. RESULTS:Median (IQR) intakes of vitamin D were generally low in this young population, ranging from 2.0 (1.9) to 2.5 (4.9) µg/day. Ninety-three and 78 % of children had intakes below 10 and 5 µg/day, respectively. While vitamin D supplement users (17 %) had the highest intakes [6.7 (6.4) µg/day] (P < 0.001), 74 % had intakes below 10 µg/day. Vitamin D-fortified foods, consumed by 77 % of children [2.2 (2.0) µg/day], made nutritionally significant contributions to intake [0.8 (1.6) µg/day], particularly in younger children [1.5 (4.6) µg/day]. Children who did not use nutritional supplements or fortified foods had significantly (P < 0.001) lower intakes of vitamin D than the other groups [1.0 (0.8) µg/day]. Our analyses show the importance of milk and yoghurt, meat and fortified ready-to-eat cereals as sources of vitamin D in this age group. The use of nutritional supplements or fortified foods at current levels does not represent a risk of intakes exceeding the European Food Safety Authority (EFSA) tolerable upper intake level (UL) (50 µg/day), as intakes did not exceed or even approach the UL (P95: 22 % of UL). CONCLUSION:Intakes of vitamin D in preschool children in Ireland are generally low. Nutritional supplements and fortified foods make significant contributions to intakes of vitamin D, without risk of unacceptably high intakes. Though supplements are effective in raising intakes of vitamin D in users, uptake is low (17 %). Food fortification may represent a suitable public health approach to increasing vitamin D intakes. The national food consumption data of Irish preschool children provide the ideal starting point for modelling of fortification scenarios to identify which foods and levels of addition will ensure effective and safe increases in vitamin D intake.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Hennessy Á,Browne F,Kiely M,Walton J,Flynn Adoi
10.1007/s00394-016-1171-7subject
Has Abstractpub_date
2017-04-01 00:00:00pages
1219-1231issue
3eissn
1436-6207issn
1436-6215pii
10.1007/s00394-016-1171-7journal_volume
56pub_type
杂志文章abstract:PURPOSE:Atherosclerosis is known to be an inflammatory disease. Dendritic cells (DCs) are essential for the regulation of the immune system. Up to 10% of the cells in atherosclerotic plaques are DCs. The cardiovascular protective effects of flavonoids (tea, wine) may be mediated by anti-inflammatory mechanisms that aff...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-010-0125-8
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:The associations between specific carotenoid intake and colorectal cancer risk remain inconsistent. The aim of this study was to examine the association between specific dietary carotenoid intake with colorectal cancer risk in Chinese adults. METHOD:From July 2010 to October 2013, 845 eligible colorectal cance...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-014-0743-7
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:In metabolic syndrome, the composition of gut microbiota has been disrupted, and is associated with left ventricular (LV) dysfunction. Several types of prebiotics, probiotics, and synbiotics have been shown to exert cardioprotection by restoring gut microbiota from dysbiosis and reducing systemic inflammation. ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1482-3
更新日期:2018-09-01 00:00:00
abstract::Isoflavones, a group of phytoestrogens, are selective oestrogen receptor (ER) modulators. They may positively impact endocrine-related conditions but the current evidence is sparse. Equol, a non-steroidal oestrogen, is produced by the metabolism of the isoflavone daidzein by intestinal bacteria. In Western countries, ...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-012-0331-7
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:Polydextrose is a low-calorie highly branched-chain glucose polymer that is poorly digested in the upper gastrointestinal tract and therefore demonstrates fibre-like properties. Fibre has been shown to increase satiety and possibly reduce food intake. Therefore, the objective of the current study was to examine...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-012-0395-4
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:This study assessed the association between animal source foods (ASF) consumption and hypertension, a recognised risk factor for cardiovascular disease. Adverse effects of red and processed meat (RPM) consumption and beneficial effects of the consumption of dairy products and other ASF have been discovered sepa...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02423-w
更新日期:2020-11-05 00:00:00
abstract:BACKGROUND:Reactive oxygen radicals have been implicated in the pathophysiology of many neurologic disorders and brain dysfunctions. Kainic acid has been used as a model agent for the study of neurotoxicity of various excitatory amino acids, since it induces neuronal damage through excessive production of reactive oxyg...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-005-0565-8
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:This project sought to test the role of diet-related inflammation in modulating the risk of oesophageal cancer. METHODS:A nationwide population-based case-control study was conducted from 1 December 1994 through 31 December 1997 in Sweden. All newly diagnosed patients with adenocarcinoma of the oesophagus or g...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0987-x
更新日期:2016-06-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake. José M. Gámez was not listed among the authors. ...
journal_title:European journal of nutrition
pub_type: 已发布勘误
doi:10.1007/s00394-020-02433-8
更新日期:2020-12-05 00:00:00
abstract:PURPOSE:Childhood obesity is an increasing problem and is accompanied by metabolic disturbances. Recently, we have identified 14 serum metabolites by a metabolomics approach (FIA-MS/MS), which showed altered concentrations in obese children as compared to normal-weight children. Obese children demonstrated higher conce...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-014-0698-8
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Lutein is a carotenoid that may play a role in eye health. Human milk typically contains higher concentrations of lutein than infant formula. Preliminary data suggest there are differences in serum lutein concentrations between breastfed and formula-fed infants. AIM OF THE STUDY:To measure the serum lutein ...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-009-0047-5
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:Intake of specific nutrients has been linked to mental states and various indices of cognitive performance although the effects are often subtle and difficult to interpret. Measurement of so-called objective variables (e.g. reaction times) is often considered to be the gold standard for assessing outcomes in th...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-015-1143-3
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The prevalence of overweight/obesity and related manifestations such as metabolic syndrome (MetS) is increasing worldwide. High energy density diets, usually with low nutrient density, are among the main causes. Some high-quality dietary patterns like the Mediterranean diet (MedDiet) have been linked to the ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-019-02087-1
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:The study aimed to investigate the potential nephroprotective effects of vitamin D3 in metabolic syndrome (MetS) and the molecular basis of the underlying mechanisms of its action. METHODS:MetS was induced in adult male Wistar rats by adding fructose (10%) to every day drinking water and salt (3%) to the diet...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02249-6
更新日期:2020-04-22 00:00:00
abstract:PURPOSE:The fat mass and obesity-associated gene (FTO) is related to obesity and coronary heart disease (CHD). We studied interaction between macronutrient intake and FTO in association with CHD risk or body mass index (BMI). METHODS:The pooled population-based case-control studies, SHEEP and INTERGENE, included 1,381...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0842-0
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate whether the daily administration of α-lipoic acid (LA) during 4 weeks prevents the redox disturbance in red blood cells (RBC) described in diabetes METHODS:Multiple low-dose streptozotocin (STZ) diabetes was induced in rats by the administration of 40 mg/kg STZ intraper...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-011-0275-3
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Both hempseed oil (HO) and flaxseed oil (FO) contain high amounts of essential fatty acids (FAs); i.e. linoleic acid (LA, 18:2n-6) and alpha-linolenic acid (ALA, 18:3n-3), but almost in opposite ratios. An excessive intake of one essential FA over the other may interfere with the metabolism of the other whil...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-006-0621-z
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:In vitro and in vivo studies suggested that flavonols, flavones, flavanones and flavan-3-ols have preventive effects on breast carcinogenesis. Epidemiological evidence about the associations between these flavonoid biomarkers and breast cancer risk is limited. This study aimed to investigate the association bet...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02331-z
更新日期:2020-07-18 00:00:00
abstract::The purpose of this review was to systematically evaluate the variability of the fatty acid composition of venous cord blood phospholipids in different populations. In an attempt to review published evidence systematically, we found 19 data sets describing fatty acid composition of venous cord blood phospholipids in 1...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-002-0366-2
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:The effect of 40 μg (1,600 IU) per day of vitamin D(3) on serum 25-hydroxyvitamin D (25(OH)D) and markers of bone and mineral metabolism was evaluated. METHODS:This intervention study was designed as a double-blind randomised controlled trial. Forty-five community-dwelling subjects (32 females), age 55-84 year...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-011-0271-7
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:The consumption of refined, fructose-enriched food continuously increases and has been linked to development of obesity, especially in young population. Low-grade inflammation and increased oxidative stress have been implicated in the pathogenesis of obesity-related disorders including type 2 diabetes. In this ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-1065-0
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Mediterranean diet (MED) is associated with health benefits, yet scarce data exist regarding the role of MED in inflammatory bowel diseases (IBD). Herein, we aimed to evaluate the association between MED and inflammatory markers in patients with IBD after pouch surgery. METHODS:Consecutive patients after po...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-019-02158-3
更新日期:2020-10-01 00:00:00
abstract:INTRODUCTION:Phenolic acids are important phenolic compounds widespread in foods, contributing to nutritional and organoleptic properties. FACTORS AFFCETING INDIVIDUAL VARIABILITY:The bioavailability of these compounds depends on their free or conjugated presence in food matrices, which is also affected by food proces...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-019-01987-6
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Dietary polyphenols have been studied for their potential effects on metabolic disorders, but studies on risk of hypertension are scarce. This study aimed to test the association between total and individual classes of dietary polyphenols and incidence of hypertension in the Polish arm of the Health, Alcohol an...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1438-7
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Dietary intakes are reflected in plasma by the presence of hundreds of exogenous metabolites and variations in endogenous metabolites. The exploration of diet-related plasma metabolic profiles could help to better understand the impact of overall diet on health. Our aim was to identify metabolomic signatures re...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02177-5
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:Constitutive activation of the Wnt signaling pathway and its downstream effectors plays a key role in neoplastic transformation. The objective of this study was to investigate the effect of ellagic acid, a plant-derived polyphenol on Wnt/β-catenin signaling and its downstream circuits- NF-κB and mitochondrial a...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-011-0288-y
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Current evidence accounts for the role of (poly)phenolic compounds in the prevention of non-communicable diseases. Detailed information on population-level intakes is required to translate these findings into recommendations. This work aimed to estimate (poly)phenol intake in the UK population using data from a...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1862-3
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Few studies have evaluated the association of fruit and vegetable (FV) intake and pre-diabetes. However, these studies are very limited and incomplete. Therefore, the aim of our study was to compare FV consumption and their subgroups between pre-diabetic and control subjects. METHODS:This case-control study in...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1569-x
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:This study was aimed to determine the impact of hydroxytyrosol (HT), a minor compound found in olive oil, on breast cancer stem cells (BCSCs) and the migration capacity of triple-negative breast cancer (TNBC) cell lines through the alteration of epithelial-to-mesenchymal transition (EMT) and embryonic signaling...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1864-1
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Iron deficiency in children is a major worldwide nutritional problem. An oat beverage was developed for 1- to 3-year-old children and different treatments were used to improve the iron bioavailability. AIM OF THE STUDY:To investigate the effects of citric acid addition, phytase treatment and supplementation...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-006-0637-4
更新日期:2007-03-01 00:00:00