The role of fortified foods and nutritional supplements in increasing vitamin D intake in Irish preschool children.

Abstract:

PURPOSE:There are limited data on the contribution of fortified foods and nutritional supplements to intakes of vitamin D in young children. Our objective was to examine the intake, adequacy, risk of excessive intake and sources of dietary vitamin D. METHODS:The nationally representative cross-sectional dietary survey of young children (aged 1-4 years) (n 500) was used to evaluate vitamin D intake and quantify the contribution of the base diet, fortified foods and nutritional supplements to total intake. RESULTS:Median (IQR) intakes of vitamin D were generally low in this young population, ranging from 2.0 (1.9) to 2.5 (4.9) µg/day. Ninety-three and 78 % of children had intakes below 10 and 5 µg/day, respectively. While vitamin D supplement users (17 %) had the highest intakes [6.7 (6.4) µg/day] (P < 0.001), 74 % had intakes below 10 µg/day. Vitamin D-fortified foods, consumed by 77 % of children [2.2 (2.0) µg/day], made nutritionally significant contributions to intake [0.8 (1.6) µg/day], particularly in younger children [1.5 (4.6) µg/day]. Children who did not use nutritional supplements or fortified foods had significantly (P < 0.001) lower intakes of vitamin D than the other groups [1.0 (0.8) µg/day]. Our analyses show the importance of milk and yoghurt, meat and fortified ready-to-eat cereals as sources of vitamin D in this age group. The use of nutritional supplements or fortified foods at current levels does not represent a risk of intakes exceeding the European Food Safety Authority (EFSA) tolerable upper intake level (UL) (50 µg/day), as intakes did not exceed or even approach the UL (P95: 22 % of UL). CONCLUSION:Intakes of vitamin D in preschool children in Ireland are generally low. Nutritional supplements and fortified foods make significant contributions to intakes of vitamin D, without risk of unacceptably high intakes. Though supplements are effective in raising intakes of vitamin D in users, uptake is low (17 %). Food fortification may represent a suitable public health approach to increasing vitamin D intakes. The national food consumption data of Irish preschool children provide the ideal starting point for modelling of fortification scenarios to identify which foods and levels of addition will ensure effective and safe increases in vitamin D intake.

journal_name

Eur J Nutr

authors

Hennessy Á,Browne F,Kiely M,Walton J,Flynn A

doi

10.1007/s00394-016-1171-7

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

1219-1231

issue

3

eissn

1436-6207

issn

1436-6215

pii

10.1007/s00394-016-1171-7

journal_volume

56

pub_type

杂志文章
  • Immunoregulatory effects of the flavonol quercetin in vitro and in vivo.

    abstract:PURPOSE:Atherosclerosis is known to be an inflammatory disease. Dendritic cells (DCs) are essential for the regulation of the immune system. Up to 10% of the cells in atherosclerotic plaques are DCs. The cardiovascular protective effects of flavonoids (tea, wine) may be mediated by anti-inflammatory mechanisms that aff...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-010-0125-8

    authors: Nickel T,Hanssen H,Sisic Z,Pfeiler S,Summo C,Schmauss D,Hoster E,Weis M

    更新日期:2011-04-01 00:00:00

  • Higher intake of carotenoid is associated with a lower risk of colorectal cancer in Chinese adults: a case-control study.

    abstract:PURPOSE:The associations between specific carotenoid intake and colorectal cancer risk remain inconsistent. The aim of this study was to examine the association between specific dietary carotenoid intake with colorectal cancer risk in Chinese adults. METHOD:From July 2010 to October 2013, 845 eligible colorectal cance...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-014-0743-7

    authors: Lu MS,Fang YJ,Chen YM,Luo WP,Pan ZZ,Zhong X,Zhang CX

    更新日期:2015-06-01 00:00:00

  • Chronic treatment with prebiotics, probiotics and synbiotics attenuated cardiac dysfunction by improving cardiac mitochondrial dysfunction in male obese insulin-resistant rats.

    abstract:PURPOSE:In metabolic syndrome, the composition of gut microbiota has been disrupted, and is associated with left ventricular (LV) dysfunction. Several types of prebiotics, probiotics, and synbiotics have been shown to exert cardioprotection by restoring gut microbiota from dysbiosis and reducing systemic inflammation. ...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-017-1482-3

    authors: Tunapong W,Apaijai N,Yasom S,Tanajak P,Wanchai K,Chunchai T,Kerdphoo S,Eaimworawuthikul S,Thiennimitr P,Pongchaidecha A,Lungkaphin A,Pratchayasakul W,Chattipakorn SC,Chattipakorn N

    更新日期:2018-09-01 00:00:00

  • Does equol production determine soy endocrine effects?

    abstract::Isoflavones, a group of phytoestrogens, are selective oestrogen receptor (ER) modulators. They may positively impact endocrine-related conditions but the current evidence is sparse. Equol, a non-steroidal oestrogen, is produced by the metabolism of the isoflavone daidzein by intestinal bacteria. In Western countries, ...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,评审

    doi:10.1007/s00394-012-0331-7

    authors: Shor D,Sathyapalan T,Atkin SL,Thatcher NJ

    更新日期:2012-06-01 00:00:00

  • Polydextrose: its impact on short-term food intake and subjective feelings of satiety in males-a randomized controlled cross-over study.

    abstract:PURPOSE:Polydextrose is a low-calorie highly branched-chain glucose polymer that is poorly digested in the upper gastrointestinal tract and therefore demonstrates fibre-like properties. Fibre has been shown to increase satiety and possibly reduce food intake. Therefore, the objective of the current study was to examine...

    journal_title:European journal of nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s00394-012-0395-4

    authors: Ranawana V,Muller A,Henry CJ

    更新日期:2013-04-01 00:00:00

  • Association between animal source foods consumption and risk of hypertension: a cohort study.

    abstract:PURPOSE:This study assessed the association between animal source foods (ASF) consumption and hypertension, a recognised risk factor for cardiovascular disease. Adverse effects of red and processed meat (RPM) consumption and beneficial effects of the consumption of dairy products and other ASF have been discovered sepa...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-020-02423-w

    authors: Liang J,Zhao JK,Wang JP,Wang T

    更新日期:2020-11-05 00:00:00

  • Neuroprotection by extract of Petasites japonicus leaves, a traditional vegetable, against oxidative stress in brain of mice challenged with kainic acid.

    abstract:BACKGROUND:Reactive oxygen radicals have been implicated in the pathophysiology of many neurologic disorders and brain dysfunctions. Kainic acid has been used as a model agent for the study of neurotoxicity of various excitatory amino acids, since it induces neuronal damage through excessive production of reactive oxyg...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-005-0565-8

    authors: Sok DE,Oh SH,Kim YB,Kang HG,Kim MR

    更新日期:2006-03-01 00:00:00

  • Diet-related inflammation and oesophageal cancer by histological type: a nationwide case-control study in Sweden.

    abstract:PURPOSE:This project sought to test the role of diet-related inflammation in modulating the risk of oesophageal cancer. METHODS:A nationwide population-based case-control study was conducted from 1 December 1994 through 31 December 1997 in Sweden. All newly diagnosed patients with adenocarcinoma of the oesophagus or g...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-015-0987-x

    authors: Lu Y,Shivappa N,Lin Y,Lagergren J,Hébert JR

    更新日期:2016-06-01 00:00:00

  • Correction to: Dietary folate intake and metabolic syndrome in participants of PREDIMED‑Plus study: a cross‑sectional study.

    abstract::The original version of this article unfortunately contained a mistake. José M. Gámez was not listed among the authors. ...

    journal_title:European journal of nutrition

    pub_type: 已发布勘误

    doi:10.1007/s00394-020-02433-8

    authors: Navarrete-Muñoz EM,Vioque J,Toledo E,Oncina-Canovas A,Martínez-González MÁ,Salas-Salvadó J,Corella D,Fitó M,Romaguera D,Alonso-Gómez ÁM,Wärnberg J,Martínez JA,Serra-Majem L,Estruch R,Tinahones FJ,Lapetra J,Pintó X,Tur J

    更新日期:2020-12-05 00:00:00

  • Changes in the serum metabolite profile in obese children with weight loss.

    abstract:PURPOSE:Childhood obesity is an increasing problem and is accompanied by metabolic disturbances. Recently, we have identified 14 serum metabolites by a metabolomics approach (FIA-MS/MS), which showed altered concentrations in obese children as compared to normal-weight children. Obese children demonstrated higher conce...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-014-0698-8

    authors: Reinehr T,Wolters B,Knop C,Lass N,Hellmuth C,Harder U,Peissner W,Wahl S,Grallert H,Adamski J,Illig T,Prehn C,Yu Z,Wang-Sattler R,Koletzko B

    更新日期:2015-03-01 00:00:00

  • Serum lutein concentrations in healthy term infants fed human milk or infant formula with lutein.

    abstract:BACKGROUND:Lutein is a carotenoid that may play a role in eye health. Human milk typically contains higher concentrations of lutein than infant formula. Preliminary data suggest there are differences in serum lutein concentrations between breastfed and formula-fed infants. AIM OF THE STUDY:To measure the serum lutein ...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00394-009-0047-5

    authors: Bettler J,Zimmer JP,Neuringer M,DeRusso PA

    更新日期:2010-02-01 00:00:00

  • Examining techniques for measuring the effects of nutrients on mental performance and mood state.

    abstract:PURPOSE:Intake of specific nutrients has been linked to mental states and various indices of cognitive performance although the effects are often subtle and difficult to interpret. Measurement of so-called objective variables (e.g. reaction times) is often considered to be the gold standard for assessing outcomes in th...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,评审

    doi:10.1007/s00394-015-1143-3

    authors: Hamer M,Dye L,Siobhan Mitchell E,Layé S,Saunders C,Boyle N,Schuermans J,Sijben J

    更新日期:2016-09-01 00:00:00

  • Effect of changes in adherence to Mediterranean diet on nutrient density after 1-year of follow-up: results from the PREDIMED-Plus Study.

    abstract:BACKGROUND:The prevalence of overweight/obesity and related manifestations such as metabolic syndrome (MetS) is increasing worldwide. High energy density diets, usually with low nutrient density, are among the main causes. Some high-quality dietary patterns like the Mediterranean diet (MedDiet) have been linked to the ...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-019-02087-1

    authors: Cano-Ibáñez N,Bueno-Cavanillas A,Martínez-González MÁ,Salas-Salvadó J,Corella D,Freixer GL,Romaguera D,Vioque J,Alonso-Gómez ÁM,Wärnberg J,Martínez JA,Serra-Majem L,Estruch R,Tinahones FJ,Lapetra J,Pintó X,Tur JA,García

    更新日期:2020-09-01 00:00:00

  • Renoprotective effects of vitamin D3 supplementation in a rat model of metabolic syndrome.

    abstract:PURPOSE:The study aimed to investigate the potential nephroprotective effects of vitamin D3 in metabolic syndrome (MetS) and the molecular basis of the underlying mechanisms of its action. METHODS:MetS was induced in adult male Wistar rat‏s by adding fructose (10%) to every day drinking water and salt (3%) to the diet...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-020-02249-6

    authors: Wahba NS,Ghareib SA,Abdel-Ghany RH,Abdel-Aal M,Alsemeh AE

    更新日期:2020-04-22 00:00:00

  • FTO gene variation, macronutrient intake and coronary heart disease risk: a gene-diet interaction analysis.

    abstract:PURPOSE:The fat mass and obesity-associated gene (FTO) is related to obesity and coronary heart disease (CHD). We studied interaction between macronutrient intake and FTO in association with CHD risk or body mass index (BMI). METHODS:The pooled population-based case-control studies, SHEEP and INTERGENE, included 1,381...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-015-0842-0

    authors: Gustavsson J,Mehlig K,Leander K,Berg C,Tognon G,Strandhagen E,Björck L,Rosengren A,Lissner L,Nyberg F

    更新日期:2016-02-01 00:00:00

  • Alpha-lipoic acid preserves the structural and functional integrity of red blood cells by adjusting the redox disturbance and decreasing O-GlcNAc modifications of antioxidant enzymes and heat shock proteins in diabetic rats.

    abstract:PURPOSE:The aim of this study was to investigate whether the daily administration of α-lipoic acid (LA) during 4 weeks prevents the redox disturbance in red blood cells (RBC) described in diabetes METHODS:Multiple low-dose streptozotocin (STZ) diabetes was induced in rats by the administration of 40 mg/kg STZ intraper...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-011-0275-3

    authors: Mirjana M,Jelena A,Aleksandra U,Svetlana D,Nevena G,Jelena M,Goran P,Melita V

    更新日期:2012-12-01 00:00:00

  • Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors.

    abstract:BACKGROUND:Both hempseed oil (HO) and flaxseed oil (FO) contain high amounts of essential fatty acids (FAs); i.e. linoleic acid (LA, 18:2n-6) and alpha-linolenic acid (ALA, 18:3n-3), but almost in opposite ratios. An excessive intake of one essential FA over the other may interfere with the metabolism of the other whil...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00394-006-0621-z

    authors: Schwab US,Callaway JC,Erkkilä AT,Gynther J,Uusitupa MI,Järvinen T

    更新日期:2006-12-01 00:00:00

  • Associations between serum concentration of flavonoids and breast cancer risk among Chinese women.

    abstract:PURPOSE:In vitro and in vivo studies suggested that flavonols, flavones, flavanones and flavan-3-ols have preventive effects on breast carcinogenesis. Epidemiological evidence about the associations between these flavonoid biomarkers and breast cancer risk is limited. This study aimed to investigate the association bet...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-020-02331-z

    authors: Feng XL,Zhan XX,Zuo LS,Mo XF,Zhang X,Liu KY,Li L,Zhang CX

    更新日期:2020-07-18 00:00:00

  • Systematic review of fatty acid composition of plasma phospholipids of venous cord blood in full-term infants.

    abstract::The purpose of this review was to systematically evaluate the variability of the fatty acid composition of venous cord blood phospholipids in different populations. In an attempt to review published evidence systematically, we found 19 data sets describing fatty acid composition of venous cord blood phospholipids in 1...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,评审

    doi:10.1007/s00394-002-0366-2

    authors: Minda H,Larque E,Koletzko B,Decsi T

    更新日期:2002-06-01 00:00:00

  • Is a daily supplementation with 40 microgram vitamin D3 sufficient? A randomised controlled trial.

    abstract:PURPOSE:The effect of 40 μg (1,600 IU) per day of vitamin D(3) on serum 25-hydroxyvitamin D (25(OH)D) and markers of bone and mineral metabolism was evaluated. METHODS:This intervention study was designed as a double-blind randomised controlled trial. Forty-five community-dwelling subjects (32 females), age 55-84 year...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00394-011-0271-7

    authors: Toss G,Magnusson P

    更新日期:2012-12-01 00:00:00

  • Fructose-enriched diet induces inflammation and reduces antioxidative defense in visceral adipose tissue of young female rats.

    abstract:PURPOSE:The consumption of refined, fructose-enriched food continuously increases and has been linked to development of obesity, especially in young population. Low-grade inflammation and increased oxidative stress have been implicated in the pathogenesis of obesity-related disorders including type 2 diabetes. In this ...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-015-1065-0

    authors: Kovačević S,Nestorov J,Matić G,Elaković I

    更新日期:2017-02-01 00:00:00

  • Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis after pouch surgery.

    abstract:BACKGROUND:Mediterranean diet (MED) is associated with health benefits, yet scarce data exist regarding the role of MED in inflammatory bowel diseases (IBD). Herein, we aimed to evaluate the association between MED and inflammatory markers in patients with IBD after pouch surgery. METHODS:Consecutive patients after po...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-019-02158-3

    authors: Godny L,Reshef L,Pfeffer-Gik T,Goren I,Yanai H,Tulchinsky H,Gophna U,Dotan I

    更新日期:2020-10-01 00:00:00

  • Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability?

    abstract:INTRODUCTION:Phenolic acids are important phenolic compounds widespread in foods, contributing to nutritional and organoleptic properties. FACTORS AFFCETING INDIVIDUAL VARIABILITY:The bioavailability of these compounds depends on their free or conjugated presence in food matrices, which is also affected by food proces...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,评审

    doi:10.1007/s00394-019-01987-6

    authors: Bento-Silva A,Koistinen VM,Mena P,Bronze MR,Hanhineva K,Sahlstrøm S,Kitrytė V,Moco S,Aura AM

    更新日期:2020-06-01 00:00:00

  • Dietary polyphenol intake and risk of hypertension in the Polish arm of the HAPIEE study.

    abstract:PURPOSE:Dietary polyphenols have been studied for their potential effects on metabolic disorders, but studies on risk of hypertension are scarce. This study aimed to test the association between total and individual classes of dietary polyphenols and incidence of hypertension in the Polish arm of the Health, Alcohol an...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-017-1438-7

    authors: Grosso G,Stepaniak U,Micek A,Kozela M,Stefler D,Bobak M,Pajak A

    更新日期:2018-06-01 00:00:00

  • Untargeted plasma metabolomic profiles associated with overall diet in women from the SU.VI.MAX cohort.

    abstract:PURPOSE:Dietary intakes are reflected in plasma by the presence of hundreds of exogenous metabolites and variations in endogenous metabolites. The exploration of diet-related plasma metabolic profiles could help to better understand the impact of overall diet on health. Our aim was to identify metabolomic signatures re...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-020-02177-5

    authors: Lécuyer L,Dalle C,Micheau P,Pétéra M,Centeno D,Lyan B,Lagree M,Galan P,Hercberg S,Rossary A,Demidem A,Vasson MP,Partula V,Deschasaux M,Srour B,Latino-Martel P,Druesne-Pecollo N,Kesse-Guyot E,Durand S,Pujos-Guillot E

    更新日期:2020-12-01 00:00:00

  • Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis.

    abstract:PURPOSE:Constitutive activation of the Wnt signaling pathway and its downstream effectors plays a key role in neoplastic transformation. The objective of this study was to investigate the effect of ellagic acid, a plant-derived polyphenol on Wnt/β-catenin signaling and its downstream circuits- NF-κB and mitochondrial a...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-011-0288-y

    authors: Anitha P,Priyadarsini RV,Kavitha K,Thiyagarajan P,Nagini S

    更新日期:2013-02-01 00:00:00

  • Dietary intake of (poly)phenols in children and adults: cross-sectional analysis of UK National Diet and Nutrition Survey Rolling Programme (2008-2014).

    abstract:PURPOSE:Current evidence accounts for the role of (poly)phenolic compounds in the prevention of non-communicable diseases. Detailed information on population-level intakes is required to translate these findings into recommendations. This work aimed to estimate (poly)phenol intake in the UK population using data from a...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-018-1862-3

    authors: Ziauddeen N,Rosi A,Del Rio D,Amoutzopoulos B,Nicholson S,Page P,Scazzina F,Brighenti F,Ray S,Mena P

    更新日期:2019-12-01 00:00:00

  • Fruit and vegetable intake and pre-diabetes: a case-control study.

    abstract:PURPOSE:Few studies have evaluated the association of fruit and vegetable (FV) intake and pre-diabetes. However, these studies are very limited and incomplete. Therefore, the aim of our study was to compare FV consumption and their subgroups between pre-diabetic and control subjects. METHODS:This case-control study in...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-017-1569-x

    authors: Safabakhsh M,Koohdani F,Bagheri F,Siassi F,Khajehnasiri F,Sotoudeh G

    更新日期:2018-12-01 00:00:00

  • Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways.

    abstract:PURPOSE:This study was aimed to determine the impact of hydroxytyrosol (HT), a minor compound found in olive oil, on breast cancer stem cells (BCSCs) and the migration capacity of triple-negative breast cancer (TNBC) cell lines through the alteration of epithelial-to-mesenchymal transition (EMT) and embryonic signaling...

    journal_title:European journal of nutrition

    pub_type: 杂志文章

    doi:10.1007/s00394-018-1864-1

    authors: Cruz-Lozano M,González-González A,Marchal JA,Muñoz-Muela E,Molina MP,Cara FE,Brown AM,García-Rivas G,Hernández-Brenes C,Lorente JA,Sanchez-Rovira P,Chang JC,Granados-Principal S

    更新日期:2019-12-01 00:00:00

  • Improved iron bioavailability in an oat-based beverage: the combined effect of citric acid addition, dephytinization and iron supplementation.

    abstract:BACKGROUND:Iron deficiency in children is a major worldwide nutritional problem. An oat beverage was developed for 1- to 3-year-old children and different treatments were used to improve the iron bioavailability. AIM OF THE STUDY:To investigate the effects of citric acid addition, phytase treatment and supplementation...

    journal_title:European journal of nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00394-006-0637-4

    authors: Zhang H,Onning G,Oste R,Gramatkovski E,Hulthén L

    更新日期:2007-03-01 00:00:00