Abstract:
:Isoflavones, a group of phytoestrogens, are selective oestrogen receptor (ER) modulators. They may positively impact endocrine-related conditions but the current evidence is sparse. Equol, a non-steroidal oestrogen, is produced by the metabolism of the isoflavone daidzein by intestinal bacteria. In Western countries, 30-50% of individuals metabolize daidzein into equol and are known as equol producers. Equol production may be the source of benefit from isoflavones in endocrine disease.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Shor D,Sathyapalan T,Atkin SL,Thatcher NJdoi
10.1007/s00394-012-0331-7subject
Has Abstractpub_date
2012-06-01 00:00:00pages
389-98issue
4eissn
1436-6207issn
1436-6215journal_volume
51pub_type
杂志文章,评审abstract:BACKGROUND:Amaranth is a crop that can be grown in different soils and climates, being resistant to high temperatures, drought, and some pests. The amaranth plant has nutritional qualities and desirable biological properties. AIM OF THE STUDY:The aim of the study is to investigate the potential antitumor properties of...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-009-0051-9
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Antioxidant defence has been reported to decrease, and oxidative stress to increase, after oral glucose loading in both normal and diabetic subjects. If confirmed in normal subjects, glucose-induced antioxidant depletion has important implications for health in relation to the modern, sugar-rich diet. AIM O...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-004-0518-7
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:The enzymes encoded by fatty acid desaturases (FADS) genes determine the desaturation of long-chain polyunsaturated fatty acids (LCPUFA). We investigated if haplotype and single nucleotide polymorphisms (SNPs) in FADS gene cluster can influence LCPUFA status in infants who received either fish oil or placebo su...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-017-1529-5
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:Observational studies have suggested that polyunsaturated fatty acids (PUFAs) may decrease Alzheimer's disease (AD) risk. In the present study, we examined this hypothesis using a Mendelian randomization analysis. METHODS:We used summary statistics data for single-nucleotide polymorphisms associated with plasm...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-019-02126-x
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Heme iron may contribute to the development of atherosclerosis by catalyzing production of hydroxyl-free radicals and promoting low-density lipoprotein oxidation. However, epidemiologic findings regarding the association between heme iron intake and risk of coronary heart disease (CHD) are inconsistent. We aime...
journal_title:European journal of nutrition
pub_type: 杂志文章,meta分析
doi:10.1007/s00394-013-0535-5
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:The relationship between 100% fruit juice (100%FJ) consumption and cardiovascular risk is object of debate: indeed, recently published investigations provided new but discrepant evidence on this important question and International dietary guidelines are not in agreement on recommendations about fruit juice con...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02426-7
更新日期:2020-11-04 00:00:00
abstract:BACKGROUND:Grapes and wine contain high concentrations of polyphenolic compounds. Although their cancer protective effect has been well documented, their activity as anticarcinogens should be cautiously considered since the molecular bases of action and their applicability to human cancer prevention are still unclear. ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-003-0398-2
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:Dietary intakes are reflected in plasma by the presence of hundreds of exogenous metabolites and variations in endogenous metabolites. The exploration of diet-related plasma metabolic profiles could help to better understand the impact of overall diet on health. Our aim was to identify metabolomic signatures re...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02177-5
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:We investigated effects of ground whole flaxseed supplementation on erythrocyte polyunsaturated fatty acids (PUFAs) and serum biomarkers of inflammation, endothelial dysfunction, oxidative stress, and thrombosis in Chinese with risk factors of metabolic syndrome (MetS). METHODS:This study was a secondary analy...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-012-0461-y
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Choline, docosahexaenoic acid (DHA), and arachidonic acid (ARA) are essential to fetal development, particularly of the brain. These components are actively enriched in the fetus. Deprivation from placental supply may therefore result in impaired accretion in preterm infants. OBJECTIVE:To determine choline,...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-016-1220-2
更新日期:2017-06-01 00:00:00
abstract::The awareness is increasing that in the colon many metabolic processes take place in relation to the fermentation of our food, which might be relevant for health and disease. However, the relation between food, colon metabolism and health or disease is far from clear. In this overview, the physiology of colonic metabo...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-002-1101-8
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:To determine the dose-response of vitamin D3 supplementation on serum 25-hydroxyvitamin D [25(OH)D] among Chinese adults. METHODS:In this 5-arm, randomized, double-blinded controlled trial, 76 healthy participants were assigned to orally administrate 0, 400, 800, 1200 or 2000 IU/d of vitamin D3 for 16 weeks. S...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-0859-4
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:The study aimed to investigate the potential nephroprotective effects of vitamin D3 in metabolic syndrome (MetS) and the molecular basis of the underlying mechanisms of its action. METHODS:MetS was induced in adult male Wistar rats by adding fructose (10%) to every day drinking water and salt (3%) to the diet...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02249-6
更新日期:2020-04-22 00:00:00
abstract:BACKGROUND:Lutein is a carotenoid that may play a role in eye health. Human milk typically contains higher concentrations of lutein than infant formula. Preliminary data suggest there are differences in serum lutein concentrations between breastfed and formula-fed infants. AIM OF THE STUDY:To measure the serum lutein ...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-009-0047-5
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To assess the effect of medium-chain fatty acid (MCFA)-rich mustard oil and polyunsaturated fatty acid (PUFA)-rich mustard oil on erythrocyte membrane composition and osmotic fragility in normal and hypercholesterolemic rats. METHOD:Membrane composition was analyzed using standard kits. Osmotic fragility was d...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-010-0150-7
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Laboratory studies have suggested that vitamin D inadequacy may be implicated in development of hypertension. Evidence from epidemiologic studies remains limited. We aim to examine the prospective associations of circulating vitamin D metabolites, vitamin D receptor (VDR) gene polymorphisms, and their interacti...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-012-0480-8
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:Ellagitannins are high molecular weight polyphenols present in high quantities in various food products. They are metabolized by human and animal gut microbiota to postbiotic metabolites-urolithins, bioavailable molecules of a low molecular weight. Following absorption in the gut, urolithins rapidly undergo pha...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02386-y
更新日期:2020-09-22 00:00:00
abstract:PURPOSE:It is thought that total energy intake in women is increased during the luteal versus follicular phase of the menstrual cycle; however, less is understood regarding changes in diet composition (i.e., macro- and micronutrient intakes) across the cycle. The aim of this study was to investigate changes in macronut...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0931-0
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the association between adipose tissue content of the plant-derived n-3 fatty acid, alpha-linolenic acid, and the rate of incident peripheral artery disease (PAD). METHODS:We conducted a case-cohort study nested within the Danish Diet, Cancer and Health cohort (n = 57,0...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-019-02159-2
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:This project sought to test the role of diet-related inflammation in modulating the risk of oesophageal cancer. METHODS:A nationwide population-based case-control study was conducted from 1 December 1994 through 31 December 1997 in Sweden. All newly diagnosed patients with adenocarcinoma of the oesophagus or g...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0987-x
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:This study aimed to assess the dietary patterns of adolescents using a food-based diet quality index and their compliance with a healthy dietary guideline METHODS: Participants included 71,553 Brazilian adolescents (12-17 years old) from the Study of Cardiovascular Risks in Adolescents (ERICA), a cross-sectiona...
journal_title:European journal of nutrition
pub_type: 杂志文章,多中心研究
doi:10.1007/s00394-019-01923-8
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:Previously, anthocyanin-rich blueberry treatments have shown positive effects on cognition in both animals and human adults. However, little research has considered whether these benefits transfer to children. Here we describe an acute time-course and dose-response investigation considering whether these cognit...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-1029-4
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To investigate whether the ingestion of olive oil having different phenolic contents influences the expression of blood pressure-related genes, involved in the renin-angiotensin-aldosterone system, in healthy humans. METHODS:A randomized, double-blind, crossover human trial with 18 healthy subjects, who ingest...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-1110-z
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Flavonoids have physiological activity and a variety of pharmacological properties, including anticancer activity in vitro, but structure-anticancer activity relationships are unclear. AIM:The objectives of this work were to investigate the activity of dietary flavonol congeners against cell lines derived f...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-011-0204-5
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Animal and laboratory studies suggest that long-chain omega-3 (n-3) fatty acids, a type of polyunsaturated fat found in fatty fish, may protect against carcinogenesis, but human studies on dietary intake of polyunsaturated fats and fish with endometrial cancer risk show mixed results. METHODS:We evaluated the ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-012-0436-z
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:To investigate whether age influences colonic polyphenol metabolism. METHODS:Healthy participants, younger (n = 8; 23-43 years) and older (n = 13; 51-76 years), followed a 3-day low-polyphenol diet (LPD) and a 3-day high-polyphenol diet (HPD). Urinary phenolic acids (PA), short chain fatty acids (SCFA), pH and...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1625-1
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:Polydextrose is a low-calorie highly branched-chain glucose polymer that is poorly digested in the upper gastrointestinal tract and therefore demonstrates fibre-like properties. Fibre has been shown to increase satiety and possibly reduce food intake. Therefore, the objective of the current study was to examine...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-012-0395-4
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:This survey aimed to assess iodine status in a female population at different ages, also investigating their eating habits. METHODS:We measured urinary iodine concentrations (UIC) in: 634 females at puberty and 361 fertile women in 246 of whom were considered also their children (134 daughters and 120 sons). A...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0853-x
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Present animal models used to emulate type 2 diabetes may not accurately reflect the metabolic changes that occur in humans. AIM OF THE STUDY:The purpose of this research was to evaluate diets reported to induce insulin resistance and impaired glucose metabolism in rats as a potentially useful model for stu...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s003940070016
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:The study of vitamin D status at population level gained relevance since vitamin D deficiency was recently suggested to trigger chronic disease. AIM OF THE STUDY:We aimed to describe vitamin D status, its association with bone and mineral metabolism and risk factors for deficiency in adults over 40 years in...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-008-0756-1
更新日期:2009-02-01 00:00:00