Abstract:
PURPOSE:This study assessed the association between animal source foods (ASF) consumption and hypertension, a recognised risk factor for cardiovascular disease. Adverse effects of red and processed meat (RPM) consumption and beneficial effects of the consumption of dairy products and other ASF have been discovered separately; however, the constrained nature of food intake has been typically ignored. We assessed the effects of substituting RPM and other ASF. METHODS:We followed-up 5394 Chinese adults (age 18-60 years) at baseline using the China Health and Nutrition Survey from 2004 to 2011. Food consumption was assessed using individual-based consecutive 24-h recall and household-based food weighing approaches. Both traditional substitution analysis and substitution analysis based on compositional transformation were used to assess substitution effects. RESULTS:In total, 1267 participants were newly diagnosed with hypertension during the median follow-up time of 6.81 years (range, 2.97-6.99 years). The traditional substitution analysis found that substituting eggs for RPM was associated with a lower risk of hypertension. The compositional transformation substitution analysis revealed that replacing RPM with any other ASF was associated with a lower risk of hypertension; it implemented substitutions of one or many ASF for RPM; it also revealed different substitution effects of RPM and dairy products, and substituting dairy products for RPM was associated with reduced hypertension risks. CONCLUSION:The compositional transformation substitution analysis considers the constrained and relative nature of food consumption. It is a flexible approach to estimating substitution effects using different patterns to obtain personalised estimation effects and provide individualised dietary recommendations.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Liang J,Zhao JK,Wang JP,Wang Tdoi
10.1007/s00394-020-02423-wsubject
Has Abstractpub_date
2020-11-05 00:00:00eissn
1436-6207issn
1436-6215pii
10.1007/s00394-020-02423-wpub_type
杂志文章abstract:PURPOSE:Iodine deficiency affects 30% of populations worldwide. The amount of thyroglobulin (Tg) in blood increases in iodine deficiency and also in iodine excess. Tg is considered as a sensitive index of iodine status in groups of children and adults, but its usefulness for individuals is unknown. The aim of this stud...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1410-6
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Uroguanylin (UGN) is a 16 amino acid peptide produced mainly by intestinal epithelial cells. Nutrients intake increases circulating levels of prouroguanylin that is processed and converted to UGN to activate the guanylyl cyclase 2C receptor (GUCY2C). Given that the UGN-GUCY2C system has been proposed as a novel...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0869-2
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND AND AIM:Breast cancer remains a leading cause of mortality among women. In metastasis, cascade migration of cancer cells and invasion of extracellular matrix (ECM) represent critical steps. Urokinase-type plasminogen activator (uPA), as well as metalloproteinases MMP-2 and MMP-9, strongly contribute to ECM r...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-013-0542-6
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Adipose tissue is now recognized as a highly active metabolic and endocrine organ. Our aim was to investigate the effect of the dietary fat on the two main adipose tissue functions, endocrine and lipid store, by analyzing the adipose tissue gene expression from metabolic syndrome patients. METHODS:A randomized...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-013-0570-2
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:It is thought that total energy intake in women is increased during the luteal versus follicular phase of the menstrual cycle; however, less is understood regarding changes in diet composition (i.e., macro- and micronutrient intakes) across the cycle. The aim of this study was to investigate changes in macronut...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0931-0
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:Breast cancer prevalence is growing worldwide. Many factors, such as diet and lifestyle could be determinants of the incidence of breast cancer. Coffee has been extensively studied in relation to several chronic diseases because of its multiple effects in health maintenance and its elevated consumption. We...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02180-w
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:The imbalance of n-6 and n-3 polyunsaturated fatty acids in the maternal diet impairs intestinal barrier development and sensitizes the colon response to inflammatory insults in the young rats. With a view to overcoming this issue, we designed this study to investigate the effect of maternal and neonatal int...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-1004-0
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Rooibos tea (Aspalathus linearis) is commonly used for hyperactive gastrointestinal, respiratory and cardiovascular disorders. AIM OF STUDY:The aqueous extract of Rooibos tea (RT) was studied for the possible bronchodilator, antispasmodic and blood pressure lowering activities in an attempt to rationalize s...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-006-0620-0
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:The fat mass and obesity-associated gene (FTO) is related to obesity and coronary heart disease (CHD). We studied interaction between macronutrient intake and FTO in association with CHD risk or body mass index (BMI). METHODS:The pooled population-based case-control studies, SHEEP and INTERGENE, included 1,381...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0842-0
更新日期:2016-02-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake. José M. Gámez was not listed among the authors. ...
journal_title:European journal of nutrition
pub_type: 已发布勘误
doi:10.1007/s00394-020-02433-8
更新日期:2020-12-05 00:00:00
abstract:OBJECTIVE:To examine the determinants of adiponectin levels (i) in 23 women with anorexia nervosa (mean BMI 15.0 +/- 1.2) and 43 healthy normal weight females (mean BMI 22.3 +/- 2.3; cross-sectional design) as well as (ii) after six and twelve weeks of weight gain in subgroups of 18 and 11 anorectic patients (mean weig...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-005-0533-3
更新日期:2005-09-01 00:00:00
abstract:PURPOSE:Evidence of an association between n-3 polyunsaturated fatty acids (PUFAs) and metabolic syndrome (MS) is limited and inconsistent. We investigated the association between n-3 PUFAs in erythrocytes and the presence of MS in Chinese adults. METHODS:The levels of α-linolenic acid (ALA), eicosapentaenoic acid (EP...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0912-3
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:The objective of the present study was to test the hypothesis that N-acetylcysteine (NAC) may play beneficial roles against intrauterine growth retardation (IUGR)-induced hepatic damage in suckling piglets. METHODS:Fourteen IUGR and seven normal birth weight (NBW) neonatal male piglets were selected. Piglets w...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-016-1322-x
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:Several epidemiological studies have demonstrated the health benefits of polyphenols, but the associations between polyphenol intake and mortality including total and major causes of death remain unclear. We investigated the associations between subjects' total polyphenol intake and their mortality from all cau...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-019-02136-9
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:A meal replacement may be an effective strategy in the management of obesity to increase antioxidant intake, attenuating oxidative stress and inflammation. In the present study, we investigated the efficacy of a new nutritional supplement to reduce metabolic risk parameters in obese women. METHODS:In a randomi...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-013-0598-3
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:Fruit and vegetable (FV) consumption and salt intake are known dietary influences on blood pressure (BP) in adults, but data on their long-term relevance during growth for later BP are rare. We aimed to examine the independent and concomitant influences of adolescent FV and salt intakes on BP in young adulthood...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-014-0804-y
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Protein-restricted diet during pregnancy is related to oxidative stress and, as a consequence, damage to nephrogenesis. We investigated the effects of vinifera grape skin extract (ACH09)-derived polyphenols on preserving renal morphology of maternal protein-restricted 1-day-old offspring. METHODS:Female C57/Bl...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0963-5
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION:Organic acids from plant food have been shown to play an important role in the prevention of chronic diseases (osteoporosis, obesity), inherent to western diets, but little is known about their bioavailability in the small intestine, information that needs to be determined in order to quantify likely effec...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-010-0112-0
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Fruits and nuts may prevent or reverse common human health conditions such as obesity, diabetes and hypertension; together, these conditions are referred to as metabolic syndrome, an increasing problem. This study has investigated the responses to ellagic acid, present in many fruits and nuts, in a diet-indu...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-012-0358-9
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To investigate whether age influences colonic polyphenol metabolism. METHODS:Healthy participants, younger (n = 8; 23-43 years) and older (n = 13; 51-76 years), followed a 3-day low-polyphenol diet (LPD) and a 3-day high-polyphenol diet (HPD). Urinary phenolic acids (PA), short chain fatty acids (SCFA), pH and...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1625-1
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:Vegetarian and vegan diets have gained popularity in Switzerland. The nutritional status of individuals who have adopted such diets, however, has not been investigated. The aim of this study was to assess the intake and status of selected vitamins and minerals among vegetarian and vegan adults living in Switzer...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-1079-7
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Vegetables and fruits are rich sources of a variety of nutrients, including vitamins (E and C), trace minerals, and dietary fibers, and many other classes of biologically active compounds such as carotenoids and polyphenols, which are often assumed to protect against degenerative pathologies such as cardiova...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-006-0594-y
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:Daily exposure to stress and excessive fructose intake coincides with the growing rate of obesity and related disorders, to which women are more prone than men. Glucocorticoids, the main regulators of energy balance and response to stress, have been associated with the development of metabolic disturbances. The...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-016-1251-8
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Inulin-type fructans or chains with mainly beta[2-1] linked fructose molecules escape the ingestion procedure in the small intestine and are fermented by the microflora, and are known to increase colonic absorption of minerals in animals. The fermentation rate in the large bowel into short-chain fatty acids ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-003-0390-x
更新日期:2003-04-01 00:00:00
abstract:PURPOSE:There is considerable variation in incremental circulating 25-hydroxyvitamin D (25OHD) levels on vitamin D supplements, even when similar age groups and identical vitamin D doses are compared. We therefore aimed to investigate the importance of body weight for the dose-response relation in circulating 25OHD. M...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-013-0634-3
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Disease preventing effects gained by garlic consumption have been recognized since early period of history, making commercially available garlic supplements attractive to the general public. Possible pharmacokinetic interactions which could occur between applied drugs and aged garlic extract (AGE) are unknow...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-010-0095-x
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:Childhood obesity is an increasing problem and is accompanied by metabolic disturbances. Recently, we have identified 14 serum metabolites by a metabolomics approach (FIA-MS/MS), which showed altered concentrations in obese children as compared to normal-weight children. Obese children demonstrated higher conce...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-014-0698-8
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Although research suggests that antioxidant supplementation can protect against exercise-induced muscle damage and oxidative stress, also delayed post-exercise muscle recovery and hindered adaptation to training were reported in the supplemented athletes. PURPOSE:The purpose of the study was to evaluate the...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-014-0757-1
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Inadequate iodine intake may result in iodine deficiency disorders (IDD). Thus, for more than 50 years, policies for the regulation of salt fortification with iodine have existed in Brazil. In 2003, a study on 6-14-year-old schoolchildren from regions of the state of São Paulo showed a median urinary iodine con...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-011-0239-7
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:Chronic sugar-sweetened beverage (SSB) consumption is associated with obesity and type 2 diabetes mellitus (T2DM). Hyperglycaemia contributes to metabolic alterations observed in T2DM, such as reduced oxidative capacity and elevated glycolytic and lipogenic enzyme expressions in skeletal muscle tissue. We aimed...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章
doi:10.1007/s00394-012-0401-x
更新日期:2013-04-01 00:00:00