Mesothelioma with superior vena cava obstruction in young female following short latency of asbestos exposure.

Abstract:

:An 18 years female was admitted with right-sided chest pain, dry cough, and low-grade fever and weight loss for last 1 month. On examination, patient had features of superior vena cava (SVC) syndrome with right-sided pleural effusion. Chest X-ray showed mediastinal widening with nonhomogenous opacity mainly in the periphery of right upper and mid zone with right-sided pleural effusion. Ultrasonography thorax confirmed mild pleural effusion. Pleural fluid analysis showed lymphocytic, exudative, low adenosine deaminase with negative for Pap smear. Contrast-enhanced computed tomography (CT) thorax revealed large extensive nodular soft tissue lesion along right mediastinum as well as costal pleura, with enlarged pretracheal lymphadenopathy and SVC obstruction. CT guided Tru-cut biopsy report came as malignant epithelial tumor with polygonal shape, abundant eosinophilic cytoplasm and nuclei with prominent nucleoli suggestive of mesothelioma of epithelioid type. The tumor cell expressed calretinin, WT-1, and immunonegative for thyroid transcription factor-1.

journal_name

J Cancer Res Ther

authors

Patra A,Kundu S,Pal A,Saha S

doi

10.4103/0973-1482.160924

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

940-2

issue

4

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2015_11_4_940_160924

journal_volume

11

pub_type

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