当前位置： SCI文献检索 > EXPERIMENTAL AND MOLECULAR PATHOLOGY期刊下所有文献 > Primary hepatic Epstein-Barr virus-associated CD30-positive peripheral T-cell lymphoma of cytotoxic phenotype.

Primary hepatic Epstein-Barr virus-associated CD30-positive peripheral T-cell lymphoma of cytotoxic phenotype.

Abstract：

:Primary hepatic peripheral T-cell lymphoma (PTCL) is exceedingly rare. We encountered such a case in a 58-year-old Hispanic female with a history of chronic sinusitis and hypothyroidism who presented with 4weeks of fever and weight loss. Laboratory studies showed altered liver function and mild pancytopenia. Hepatitis and HIV infection were excluded by negative serological tests. A computed tomography (CT) scan showed innumerable small low-density lesions throughout the liver without splenomegaly or lymphadenopathy. CT-guided liver core biopsy showed scattered small lymphoid aggregates located mainly in the portal tracts and periportal regions. Within the lymphoid aggregates, scattered large pleomorphic lymphoma cells were seen, admixed with smaller lymphoid cells and histiocytes. By immunohistochemistry, the lymphoma cells expressed CD2, CD3, CD8, CD30, CD43, CD45, granzyme B, TIA-1, and negative for CD4, CD5, CD7, CD56, βF1, ALK-1, and B-cell markers. In situ hybridization for Epstein-Barr virus-encoded RNA (EBER) was positive in some lymphoma cells. To our knowledge, this is the first reported case of primary hepatic Epstein-Barr virus-associated PTCL with CD30 expression.

journal_name

Exp Mol Pathol

journal_title

Experimental and molecular pathology

authors

Peng Y,Cai J,Yue C,Qing X

doi

10.1016/j.yexmp.2016.01.002

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

207-11

issue

1

eissn

0014-4800

issn

1096-0945

pii

S0014-4800(16)00003-4

journal_volume

100

pub_type

杂志文章

相关文献

EXPERIMENTAL AND MOLECULAR PATHOLOGY文献大全
  • The Apolipoprotein B/Apolipoprotein A 1 ratio in relation to metabolic syndrome and its components in a sample of the Tunisian population.

    abstract：OBJECTIVE:This study was undertaken to investigate the relationship between the Apolipoprotein B/Apolipoprotein A 1 (ApoB/ApoA 1) ratio and various characteristics of the metabolic syndrome (MetS) in a sample of the Tunisian population. METHODS:The study included 330 adults aged 35-74 (172 patients with MetS and 158 c...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2011.06.007

    authors： Belfki H,Ben Ali S,Bougatef S,Ben Ahmed D,Haddad N,Jmal A,Abdennebi M,Ben Romdhane H

    更新日期：2011-10-01 00:00:00

  • Human umbilical cord mesenchymal stem cell-derived exosomes suppress dermal fibroblasts-myofibroblats transition via inhibiting the TGF-β1/Smad 2/3 signaling pathway.

    abstract：OBJECTIVE:Exosomes originated from mesenchymal stem cells (MSCs) benefit wound healing. This study investigated effects of exosomes originated from human umbilical cord MSCs (hUC-MSCs) on dermal fibroblasts-myofibroblasts transition via the TGF-β1/Smad2/3 signaling pathway. METHODS:Firstly, hUC-MSCs were collected and...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2020.104468

    authors： Hu J,Chen Y,Huang Y,Su Y

    更新日期：2020-08-01 00:00:00

  • Dsp rul: a spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome.

    abstract：:Studies of spontaneous mutations in mice have provided valuable disease models and important insights into the mechanisms of human disease. Ruffled (rul) is a new autosomal recessive mutation causing abnormal hair coat in mice. The rul allele arose spontaneously in the RB156Bnr/EiJ inbred mouse strain. In addition to ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2015.01.015

    authors： Herbert Pratt C,Potter CS,Fairfield H,Reinholdt LG,Bergstrom DE,Harris BS,Greenstein I,Dadras SS,Liang BT,Schofield PN,Sundberg JP

    更新日期：2015-04-01 00:00:00

  • Protection against cellular damage in the rat heart by hyperosmotic solutions.

    abstract：:In this comparative study, rat hearts were perfused at 37 degrees C with three clearly defined protocols: the Ca2+ paradox, the O(2) paradox, and with 20 mM caffeine. Each protocol involved an initial priming (Ca(2+)(0) depletion or anoxia; stage 1) and subsequent full activation (Ca(2+)(0) repletion, caffeine or reox...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1006/exmp.1999.2275

    authors： Harding RJ,Duncan CJ

    更新日期：1999-10-01 00:00:00

  • Serum autoantibody biomarkers for age-related macular degeneration and possible regulators of neovascularization.

    abstract：:Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrial counties. Its pathogenesis is at least partially mediated by immunological factors, including a possible autoimmune response. To date, only a few antibodies have been identified in sera from patients with AMD. In order ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2011.09.017

    authors： Morohoshi K,Patel N,Ohbayashi M,Chong V,Grossniklaus HE,Bird AC,Ono SJ

    更新日期：2012-02-01 00:00:00

  • Respiratory reovirus 1/L induction of diffuse alveolar damage: a model of acute respiratory distress syndrome.

    abstract：:Acute respiratory distress syndrome (ARDS) is a clinical syndrome that is characterized by diffuse alveolar damage usually secondary to an intense host inflammatory response of the lung to a pulmonary or extrapulmonary infectious or noninfectious insult. In this report we describe a unique animal model in which CBA/J ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1006/exmp.2001.2414

    authors： London L,Majeski EI,Paintlia MK,Harley RA,London SD

    更新日期：2002-02-01 00:00:00

  • Megakaryocytes and platelet homeostasis in diffuse alveolar damage.

    abstract：:Platelet homeostasis reflects a balance between the production of platelets via cytoplasmic fragmentation of megakaryocytes in the pulmonary microvasculature and their catabolism. Increased numbers of megakaryocytes are entrapped in the injured lung, potentially affecting circulating platelet counts. We enumerated pul...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2007.08.005

    authors： Mandal RV,Mark EJ,Kradin RL

    更新日期：2007-12-01 00:00:00

  • Polymorphisms of APLN-APLNR system are associated with essential hypertension in Mexican-Mestizo individuals.

    abstract：:The aim of this study was to evaluate if polymorphisms of APLN and APLNR genes may play a role as susceptibility markers for hypertension in a group of Mexican-Mestizo patients. A case-control study was carried out including normotensive and hypertensive individuals. For these, two polymorphisms of APLN (rs3761581 and...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2016.07.007

    authors： Esteban-Martínez RL,Pérez-Razo JC,Vargas-Alarcón G,Martínez-Rodríguez N,Cano-Martínez LJ,López-Hernández LB,Rojano-Mejía D,Canto P,Coral-Vazquez RM

    更新日期：2016-08-01 00:00:00

  • Localization of fibrinogen during aggregation of avian thrombocytes.

    abstract：:The thrombocyte is the avian equivalent of the mammalian blood platelet and is involved in hemostasis through a fibrinogen-mediated process. Although fibrinogen has been implicated as a molecular bridge between activated cells during aggregation, the location of this molecule and its receptor on thrombocytes has not b...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1006/exmp.1994.1035

    authors： O'Toole ET,Hantgan RR,Lewis JC

    更新日期：1994-12-01 00:00:00

  • RXRalpha-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity.

    abstract：:Retinoids influence the pathogenesis of alcohol liver disease (ALD). To analyze the impact of retinoid X receptor alpha (RXRalpha) on ALD, alcohol-induced hepatotoxicity was studied using mice fed ethanol intragastrically for 25 days. Alcohol-induced microvesicular fat around the central vein and drug-induced morpholo...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/s0014-4800(03)00091-1

    authors： Dai T,Wu Y,Leng AS,Ao Y,Robel RC,Lu SC,French SW,Wan YJ

    更新日期：2003-12-01 00:00:00

  • Preferential expression of the cell adhesion molecule CD44 in papillary thyroid carcinoma.

    abstract：:CD44 is a polymorphic family of immunologically related integral membrane glycoproteins associated with cell matrix adhesion, lymphocyte activation and targeting, and tumor growth and metastasis. We studied CD44 expression in 114 formalin-fixed paraffin-embedded thyroid tumors using the A3D8 anti-human CD44 monoclonal...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1006/exmp.1994.1037

    authors： Figge J,del Rosario AD,Gerasimov G,Dedov I,Bronstein M,Troshina K,Alexandrova G,Kallakury BV,Bui HX,Bratslavsky G

    更新日期：1994-12-01 00:00:00

  • A time course study demonstrating RNA stability in postmortem skin.

    abstract：:Knowledge of the factors regulating the rate of mRNA degradation, including postmortem delay, is important in determining the reliability of gene expression patterns in dermal tissue. Since RNA stability can be tissue dependent, this study evaluates the effect of postmortem interval on the integrity of total RNA or th...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2006.11.001

    authors： Gopee NV,Howard PC

    更新日期：2007-08-01 00:00:00

  • Experimental strategies to improve in vitro models of renal ischemia.

    abstract：:Ischemia has elicited a great deal of interest among the scientific community due to its role in life-threatening pathologies such as cancer, stroke, acute renal failure, and myocardial infarction. Oxygen deprivation (hypoxia) associated with ischemia has recently become a subject of intense scrutiny. New investigator...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章,评审

    doi：10.1016/j.yexmp.2007.03.002

    authors： Russ AL,Haberstroh KM,Rundell AE

    更新日期：2007-10-01 00:00:00

  • Delta-aminolevulinic dehydratase is a proteasome interacting protein.

    abstract：:The proteasome interacts with a large number of proteins which regulate specific cellular functions. The focus of this study is to examine the proteasome interaction with Delta-aminolevulinate dehydratase (ALAD). ALAD is involved in the heme biosynthesis pathway and was co-isolated, with the 20S proteasome using sever...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2011.05.003

    authors： Bardag-Gorce F,French SW

    更新日期：2011-10-01 00:00:00

  • Alcoholic and non-alcoholic steatohepatitis.

    abstract：:This paper is based upon the "Charles Lieber Satellite Symposia" organized by Manuela G. Neuman at the Research Society on Alcoholism (RSA) Annual Meetings, 2013 and 2014. The present review includes pre-clinical, translational and clinical research that characterize alcoholic liver disease (ALD) and non-alcoholic ste...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章,评审

    doi：10.1016/j.yexmp.2014.09.005

    authors： Neuman MG,French SW,French BA,Seitz HK,Cohen LB,Mueller S,Osna NA,Kharbanda KK,Seth D,Bautista A,Thompson KJ,McKillop IH,Kirpich IA,McClain CJ,Bataller R,Nanau RM,Voiculescu M,Opris M,Shen H,Tillman B,Li J,Liu H

    更新日期：2014-12-01 00:00:00

  • Ski diminishes TGF-β1-induced myofibroblast phenotype via up-regulating Meox2 expression.

    abstract：OBJECTIVE:The aim of the present work was to investigate the mechanism of transforming growth factor (TGF)-β1 and Sloan-Kettering Institute (Ski) in the pathogenesis of hypertrophic scars (HS). BACKGROUND:Wound healing is an inherent process, but the aberrant wound healing of skin injury may lead to HS. There has been...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章,收录出版

    doi：10.1016/j.yexmp.2014.11.002

    authors： Chen Z,Li W,Ning Y,Liu T,Shao J,Wang Y

    更新日期：2014-12-01 00:00:00

  • Neurotoxicity of dichlorvos: effect on antioxidant defense system in the rat central nervous system.

    abstract：:The effect of dichlorvos exposure (5 mg kg-1 body wt, ip) on lipid peroxidation and antioxidant defense system in different regions of the rat central nervous system was studied. In the present paper an inhibition of acetylcholinesterase activity was used as an index of dichlorvos neurotoxicity. We observed significan...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/0014-4800(92)90031-6

    authors： Julka D,Pal R,Gill KD

    更新日期：1992-04-01 00:00:00

  • Anti-apoptotic PTD-FNK protein suppresses lipopolysaccharide-induced acute lung injury in rats.

    abstract：:The present study was aimed at clarifying the effects of an anti-apoptotic protein for modulating symptoms in acute lung injury (ALI). From Bcl-x(L), a Bcl-2 family member, we constructed an artificial protein (FNK) and fused it with the protein transduction domain (PTD) of the HIV/Tat protein (PTD-FNK) to facilitate ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2007.08.016

    authors： Chen H,Zhang L,Jin Z,Jin E,Fujiwara M,Ghazizadeh M,Asoh S,Ohta S,Kawanami O

    更新日期：2007-12-01 00:00:00

  • Three discrete areas within the chromosomal 8p21.3-23 region are associated with the development of breast carcinoma of Indian patients.

    abstract：:Deletion in the 22.9 -Mb chromosomal (chr.) 8p21.3-23 region has been shown to be necessary for the development of breast carcinoma (CaBr). In this study, we have attempted to detect the minimal deleted region(s) in the chr.8p21.3-23 region in 62 primary breast lesions having 56 CaBr tumors and six other breast lesion...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2004.01.002

    authors： Bhattacharya N,Chunder N,Basu D,Roy A,Mandal S,Majumder J,Roychowdhury S,Panda CK

    更新日期：2004-06-01 00:00:00

  • Mitochondrial dysfunction and molecular pathways of disease.

    abstract：:Since the first mitochondrial dysfunction was described in the 1960s, the medicine has advanced in its understanding the role mitochondria play in health, disease, and aging. A wide range of seemingly unrelated disorders, such as schizophrenia, bipolar disease, dementia, Alzheimer's disease, epilepsy, migraine headach...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章,评审

    doi：10.1016/j.yexmp.2006.09.008

    authors： Pieczenik SR,Neustadt J

    更新日期：2007-08-01 00:00:00

  • In human epidermis, beta-defensin 2 is packaged in lamellar bodies.

    abstract：:The skin presents a mechanical, as well as an immunological barrier to infection, and displays considerable innate immune capacity. Recently, cultured human keratinocytes were described to produce and export a microbicidal peptide human beta-defensin 2 (HBD-2). Immunogold was used to label ultrathin cryosections of st...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/s0014-4800(02)00023-0

    authors： Oren A,Ganz T,Liu L,Meerloo T

    更新日期：2003-04-01 00:00:00

  • The role of β-catenin and paired-like homeobox 2B (PHOX2B) expression in neuroblastoma patients; predictive and prognostic value.

    abstract：BACKGROUND:The expression of β-catenin and paired-like homeobox 2B (PHOX2B) expression were assessed in Neuroblastoma (NB) patients as a diagnostic, prognostic and/or predictive markers. METHODS:Bone marrow (BM) samples of 52 NB patients were assessed for the expression of β-catenin by immunohistochemistry (IHC), and ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2019.104272

    authors： El-Shazly SS,Hassan NM,Abdellateif MS,El Taweel MA,Abd-Elwahab N,Ebeid EN

    更新日期：2019-10-01 00:00:00

  • Annulate lamellae in guinea pig Sertoli cells.

    abstract：:Unilateral torsion of the spermatic cord was surgically induced in 24 Hartley strain guinea pigs. Groups of six animals were sacrificed 4, 8, 12, and 16 months after the surgery and testes were excised. Nine animals has severely damaged testes. Extensive study on the Sertoli cells of each of these nine animals was car...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/0014-4800(86)90072-9

    authors： Chakraborty J,Sinha Hikim AP,Jhunjhunwala JS

    更新日期：1986-04-01 00:00:00

  • Abnormal accumulation of elastin-associated microfibrils during elastolysis in the arterial wall.

    abstract：:We examined the correlation between elastolysis and abnormal accumulation of microfibrils in the arteries of rabbits using light and electron microscopic and tissue culture techniques. Partial constriction of the common carotid arteries of rabbits gave rise to gradual atrophy of the media with elastolysis and an unusu...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/0014-4800(90)90054-h

    authors： Katsuda S,Okada Y,Nakanishi I

    更新日期：1990-02-01 00:00:00

  • Keratinocyte growth factor-transfection-stimulated adhesion of colorectal cancer cells to extracellular matrices.

    abstract：:The keratinocyte growth factor (KGF) regulates cell growth and behavior in an autocrine or paracrine manner. In colorectal cancer tissues, KGF is expressed in tumor cells and adjacent stromal fibroblasts. We have constructed a KGF-gene-transfected cell line (HCT15-KGF) from a colorectal cancer cell line, HCT-15, that ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2007.07.001

    authors： Kudo M,Ishiwata T,Nakazawa N,Kawahara K,Fujii T,Teduka K,Naito Z

    更新日期：2007-12-01 00:00:00

  • Extracellular and cell-associated localizations of plasminogen activators and plasminogen activator inhibitor-1 in cultured endothelium.

    abstract：:The extracellular localizations of urokinase-type plasminogen activator (uPA), tissue-type plasminogen activator (tPA), and plasminogen activator inhibitor-1 (PAI-1) were examined in cultured bovine capillary endothelial cells (BCEs) by an immunofluorescence method using BCEs treated with or without saponin and focal ...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/0014-4800(91)90046-z

    authors： Murata T,Nakashima Y,Yasunaga C,Maeda K,Sueishi K

    更新日期：1991-10-01 00:00:00

  • Integrin characterization in pulmonary bronchioles.

    abstract：:Integrins are a family of cell surface glycoproteins that act as receptors for ECM proteins or for membrane bound counter-receptors on other cells. The integrin receptor family of vertebrates includes at least 16 distinct alpha subunits and at least 8 beta subunits which can associate to form more than 20 distinct int...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2005.04.004

    authors： Blundell RA,Harrison DJ

    更新日期：2005-08-01 00:00:00

  • The role of TRB3 in mast cells sensitized with monomeric IgE.

    abstract：:Mast cells play a key role in immunoglobulin E (IgE)-associated allergic disorders; however, the cellular effects of sensitization remain poorly understood. Using gene microarrays and the multiplexing ELISA method, we examined the effects of sensitization on RBL-CCR1 cell transcription and chemokine/cytokine secretion...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2012.09.008

    authors： Kuo CH,Morohoshi K,Aye CC,Garoon RB,Collins A,Ono SJ

    更新日期：2012-12-01 00:00:00

  • Maternal mosaicism underlies the inheritance of a rare germline AKT3 variant which is responsible for megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome in two Roma half-siblings.

    abstract：:Megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) syndrome is a developmental brain disorder characterized by an enlarged brain size with bilateral perisylvian polymicrogyria and a variable degree of ventriculomegaly. MPPH syndrome is associated with oromotor dysfunction, epilepsy, intellectual disability...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2020.104471

    authors： Szalai R,Melegh BI,Till A,Ripszam R,Csabi G,Acharya A,Schrauwen I,Leal SM,Komoly S,Kosztolanyi G,Hadzsiev K

    更新日期：2020-08-01 00:00:00

  • Linking chronic wasting disease to scrapie by comparison of Spiroplasma mirum ribosomal DNA sequences.

    abstract：:Transmissible spongiform encephalopathies (TSE) are fatal neurodegenerative diseases of man and animals and are transmitted by a filterable pathogen whose identity is currently unresolved. Our data indicates that Spiroplasma, a wall-less bacterium, is involved in the pathogenesis of TSE. We searched for Spiroplasma ri...

    journal_title：Experimental and molecular pathology

    pub_type： 杂志文章

    doi：10.1016/j.yexmp.2004.02.002

    authors： Bastian FO,Dash S,Garry RF

    更新日期：2004-08-01 00:00:00