Efficacy comparison between cryoablation and radiofrequency ablation for patients with cavotricuspid valve isthmus dependent atrial flutter: a meta-analysis.

abstract：:Fanconi Anemia is a rare genetic disease associated with DNA repair defects, congenital abnormalities and infertility. Most of FA pathway is evolutionary conserved, allowing dissection and mechanistic studies in simpler model systems such as Caenorhabditis elegans. In the present study, we employed C. elegans to bette...

journal_title：Scientific reports

authors： Germoglio M,Valenti A,Gallo I,Forenza C,Santonicola P,Silva N,Adamo A

更新日期：2020-01-09 00:00:00

abstract：:Myocardial ischemia/reperfusion (I/R) injury detrimentally alters the prognosis of patients undergoing revascularization after acute myocardial infarction. Our previous study demonstrated that NF-κB-induced autophagy plays a detrimental role in cardiac I/R injury using a rabbit myocardial I/R model. In this study, we ...

journal_title：Scientific reports

authors： Zeng M,Wei X,Wu Z,Li W,Zheng Y,Li B,Meng X,Fu X,Fei Y

更新日期：2016-11-18 00:00:00

abstract：:Gamma radiation is a commonly used adjuvant treatment for abdominally localized cancer. Since its therapeutic potential is limited due to gastrointestinal (GI) syndrome, elucidation of the regenerative response following radiation-induced gut injury is needed to develop a preventive treatment. Previously, we showed th...

journal_title：Scientific reports

authors： Orzechowska EJ,Katano T,Bialkowska AB,Yang VW

更新日期：2020-10-27 00:00:00

abstract：:Increasing evidence suggests that pathological hallmarks of chronic degenerative syndromes progressively spread among interconnected brain areas in a disease-specific stereotyped pattern. Functional brain imaging from patients affected by various neurological syndromes such as traumatic brain injury and stroke indicat...

journal_title：Scientific reports

authors： Deleglise B,Lassus B,Soubeyre V,Doulazmi M,Brugg B,Vanhoutte P,Peyrin JM

更新日期：2018-08-02 00:00:00

abstract：:Frailty is defined as a decline in an organism's physiological reserves resulting in increased vulnerability to stressors. In humans, a single continuous variable, the so-called Frailty Index (FI), can be obtained by multidimensionally assessing the biological complexity of an ageing organism. Here, we evaluate this v...

journal_title：Scientific reports

authors： Banzato T,Franzo G,Di Maggio R,Nicoletto E,Burti S,Cesari M,Canevelli M

更新日期：2019-11-14 00:00:00

abstract：:The overall goal of this work was to measure the efficacy of fMRI for predicting whether a dog would be a successful service dog. The training and imaging were performed in 49 dogs entering service training at 17-21 months of age. 33 dogs completed service training and were matched with a person, while 10 were release...

journal_title：Scientific reports

authors： Berns GS,Brooks AM,Spivak M,Levy K

更新日期：2017-03-07 00:00:00

abstract：:Remote earthquake triggering is a well-established phenomenon. Triggering is commonly identified from statistically significant increases in earthquake rate coincident with the passage of seismic energy. In establishing rate changes, short duration earthquake catalogs are commonly used, and triggered sequences are not...

journal_title：Scientific reports

authors： Pankow KL,Kilb D

更新日期：2020-03-05 00:00:00

abstract：:Retrotransposons can represent half of eukaryotic genomes. Retrotransposon dysregulation destabilizes genomes and has been linked to various human diseases. Emerging regulators of retromobility include RNA-DNA hybrid-containing structures known as R-loops. Accumulation of these structures at the transposons of yeast 1...

journal_title：Scientific reports

authors： Todd LA,Hall AC,Pietrobon V,Chan JNY,Laflamme G,Mekhail K

更新日期：2020-09-29 00:00:00

abstract：:Isoliquiritigenin (ISL), a natural flavonoid extracted from licorice, has been demonstrated to exert attenuation of osteoclastogenesis and anti-angiogenesis activity in a wide variety of cells. Here, we first evaluated the effects of ISL on pathogenesis of osteoarthritis in a mouse model of OA. The data showed that IS...

journal_title：Scientific reports

authors： Ji B,Zhang Z,Guo W,Ma H,Xu B,Mu W,Amat A,Cao L

更新日期：2018-01-29 00:00:00

abstract：:We aimed to evaluate the etiologies of constipation in patients with anorectal malformations having a good prognosis for bowel control but a high risk of constipation. We included twenty-five patients from the Odense university hospital in Denmark. Patients were subjected to colon transit time examination and high res...

journal_title：Scientific reports

authors： Bjørsum-Meyer T,Christensen P,Baatrup G,Jakobsen MS,Asmussen J,Qvist N

更新日期：2020-11-12 00:00:00

abstract：:Elucidating arbuscular mycorrhizal (AM) fungal responses to elevation changes is critical to improve understanding of microbial function in ecosystems under global asymmetrical climate change scenarios. Here we examined AM fungal community in a two-year reciprocal translocation of vegetation-intact soil blocks along a...

journal_title：Scientific reports

authors： Yang W,Zheng Y,Gao C,Duan JC,Wang SP,Guo LD

更新日期：2016-11-09 00:00:00

abstract：:Conventional myeloablative conditioning (MAC) regimens often cause severe regimen-related toxicity (RRT). Furthermore, many patients suffer from poor quality of life in accordance with the increase in long-term survivors. We therefore devised a reduced-toxicity myeloablative conditioning (RTMAC) regimen consisting of ...

journal_title：Scientific reports

authors： Hirabayashi K,Nakazawa Y,Sakashita K,Kurata T,Saito S,Yoshikawa K,Tanaka M,Yanagisawa R,Koike K

更新日期：2014-11-06 00:00:00

abstract：:Adenosine-to-Inosine (A-to-I) RNA editing is the most prevalent post-transcriptional modification of RNA molecules. Researchers have attempted to find reliable RNA editing using next generation sequencing (NGS) data. However, most of these attempts suffered from a high rate of false positives, and they did not conside...

journal_title：Scientific reports

authors： Hwang W,Calza S,Silvestri M,Pawitan Y,Lee Y

更新日期：2019-03-25 00:00:00

abstract：:This study aimed to detect the spatial distribution and high-risk clusters of female breast cancer mortality for the years 2011 to 2013 in Shandong Province, China. The urban-rural difference in the spatial distribution and clusters of disease mortality were also examined. Breast cancer mortality data were obtained fr...

journal_title：Scientific reports

authors： Chu J,Zhou C,Guo X,Sun J,Xue F,Zhang J,Lu Z,Fu Z,Xu A

更新日期：2017-03-07 00:00:00

abstract：:Niemann-Pick type C1 (NPC1) disease is a rare autosomal recessive, neurodegenerative lysosomal storage disorder, which presents with a range of clinical phenotypes and hence diagnosis remains a challenge. In view of these difficulties, the search for a novel, NPC1-specific biomarker (or set of biomarkers) is a topic o...

journal_title：Scientific reports

authors： Probert F,Ruiz-Rodado V,Vruchte DT,Nicoli ER,Claridge TDW,Wassif CA,Farhat N,Porter FD,Platt FM,Grootveld M

更新日期：2017-07-24 00:00:00

abstract：:2D transition metal dichalcogenides (TMDs) have attracted a lot of attention recently for energy-efficient tunneling-field-effect transistor (TFET) applications due to their excellent gate control resulting from their atomically thin dimensions. However, most TMDs have bandgaps (Eg) and effective masses (m(*)) outside...

journal_title：Scientific reports

authors： Ameen TA,Ilatikhameneh H,Klimeck G,Rahman R

更新日期：2016-06-27 00:00:00

abstract：:Vascular endothelial growth factor receptor-2 (VEGFR2) and its ligands (VEGFs) are crucial players in vasculogenesis and angiogenesis. General blocking of this signaling system with antibodies or small molecule inhibitors is an established strategy to treat cancer and age-related macular degeneration. Nevertheless, th...

journal_title：Scientific reports

authors： Xie Y,Mansouri M,Rizk A,Berger P

更新日期：2019-09-16 00:00:00

abstract：:Phagocytosis is a required mechanism for the defense against pathogens. Staphylococcus aureus, an important bacterial pathogen, can promptly escape from phagosomes and proliferate within the cytoplasm of host. However, the mechanism of phagocytosis against S. aureus has not been intensively investigated. In this study...

journal_title：Scientific reports

authors： Zhu F,Zhou Y,Jiang C,Zhang X

更新日期：2015-10-07 00:00:00

abstract：:We present two transmission-mode dielectric Fresnel-Zone Plate Lens (FZPL) antennas for use within the V-band spectrum. The proposed FZPs are realized via pure plastic material using two different additive manufacturing processes. The proposed FZP lenses are designed with half (λ/2) and quarter (λ/4) phase correction ...

journal_title：Scientific reports

authors： Pourahmadazar J,Denidni TA

更新日期：2018-03-28 00:00:00

abstract：:Rheumatoid arthritis is characterised by synovial inflammation and proliferation of fibroblast-like synoviocytes. The induction of apoptosis has long been proposed as a target for proliferative autoimmune diseases, and has further been shown to act as a successful treatment of experimental models of arthritis, such as...

journal_title：Scientific reports

authors： Hellvard A,Zeitlmann L,Heiser U,Kehlen A,Niestroj A,Demuth HU,Koziel J,Delaleu N,Jan Potempa,Mydel P

更新日期：2016-08-11 00:00:00

abstract：:The synthetic cyclic hexapeptide cWFW (cyclo(RRRWFW)) has a rapid bactericidal activity against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has, however, remained elusive. In contrast to most antimicrobial peptides, cWFW neither permeabilizes the membrane nor translocates to the cytoplas...

journal_title：Scientific reports

authors： Scheinpflug K,Wenzel M,Krylova O,Bandow JE,Dathe M,Strahl H

更新日期：2017-03-09 00:00:00

abstract：:Machine learning is a well-known approach for virtual screening. Recently, deep learning, a machine learning algorithm in artificial neural networks, has been applied to the advancement of precision medicine and drug discovery. In this study, we performed comparative studies between deep neural networks (DNN) and othe...

journal_title：Scientific reports

authors： Tsou LK,Yeh SH,Ueng SH,Chang CP,Song JS,Wu MH,Chang HF,Chen SR,Shih C,Chen CT,Ke YY

更新日期：2020-10-08 00:00:00

abstract：:Skeletal muscle thickness is a valuable indicator of several aspects of a muscle's functional capabilities. We used computational analysis of ultrasound images, recorded from 10 humans walking and running at a range of speeds (0.7-5.0 m s-1), to quantify interactions in thickness change between three ankle plantar fle...

journal_title：Scientific reports

authors： Hodson-Tole EF,Lai AKM

更新日期：2019-10-21 00:00:00

abstract：:Triple-negative breast cancers (TNBC) are unlikely to respond to hormonal therapies and anti-HER2-targeted therapies. TNBCs overexpress EGFR and exhibit constitutive activation of the PI3K/AKT/mTOR signalling pathway. We hypothesized that simultaneously blocking EGFR and mTOR could be a potential therapeutic strategy ...

journal_title：Scientific reports

authors： El Guerrab A,Bamdad M,Bignon YJ,Penault-Llorca F,Aubel C

更新日期：2020-04-14 00:00:00

abstract：:This paper presents the results of the experiments which were performed using the optical biopsy system specially developed for in vivo tissue classification during the percutaneous needle biopsy (PNB) of the liver. The proposed system includes an optical probe of small diameter acceptable for use in the PNB of the li...

journal_title：Scientific reports

authors： Dremin V,Potapova E,Zherebtsov E,Kandurova K,Shupletsov V,Alekseyev A,Mamoshin A,Dunaev A

更新日期：2020-08-26 00:00:00

abstract：:Incompatible patterns viewed by each of the two eyes can provoke binocular rivalry, a competition of perception. Levelt's first law predicts that a highly visible stimulus will predominate over a less visible stimulus during binocular rivalry. In a behavioural study, we made a counterintuitive observation: high visibi...

journal_title：Scientific reports

authors： Skerswetat J,Formankiewicz MA,Waugh SJ

更新日期：2018-09-26 00:00:00

abstract：:Three carbapenem-resistant Escherichia coli were recovered from rectal swabs of different patients in a tertiary hospital and were found carrying bla NDM-4, an uncommon bla NDM variant. Genome sequences of the isolates were obtained using Illumina technology and the long-read MinION sequencer. The isolates belonged to...

journal_title：Scientific reports

authors： Zhang X,Feng Y,Zhou W,McNally A,Zong Z

更新日期：2018-01-10 00:00:00

abstract：:Detailed structural analyses of the mushroom body which plays critical roles in olfactory learning and memory revealed that it is directly connected with multiple primary sensory centers in Drosophila. Connectivity patterns between the mushroom body and primary sensory centers suggest that each mushroom body lobe proc...

journal_title：Scientific reports

authors： Yagi R,Mabuchi Y,Mizunami M,Tanaka NK

更新日期：2016-07-11 00:00:00

abstract：:Data-independent acquisition mass spectrometry promises higher performance in terms of quantification and reproducibility compared to data-dependent acquisition mass spectrometry methods. To enable high-accuracy quantification of Staphylococcus aureus proteins, we have developed a global ion library for data-independe...

journal_title：Scientific reports

authors： Michalik S,Depke M,Murr A,Gesell Salazar M,Kusebauch U,Sun Z,Meyer TC,Surmann K,Pförtner H,Hildebrandt P,Weiss S,Palma Medina LM,Gutjahr M,Hammer E,Becher D,Pribyl T,Hammerschmidt S,Deutsch EW,Bader SL,Hecker M,Mo

更新日期：2017-09-08 00:00:00

abstract：:This study examined the performance and photo-bias stability of double-channel ZnSnO/InZnO (ZTO/IZO) thin-film transistors. The field-effect mobility (μFE) and photo-bias stability of the double-channel device were improved by increasing the thickness of the front IZO film (t(int)) compared to the single-ZTO-channel d...

journal_title：Scientific reports

authors： Jung HY,Kang Y,Hwang AY,Lee CK,Han S,Kim DH,Bae JU,Shin WS,Jeong JK

更新日期：2014-01-20 00:00:00