Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies.

abstract：:Endoplasmic reticulum (ER) stress preconditioning protects cells against methylmercury (MeHg) cytotoxicity by inducing integrated stress responses such as eIF2α phosphorylation, ATF4 accumulation, and nonsense-mediated mRNA decay (NMD) suppression. Here we demonstrated that ER stress preconditioning results in the upr...

journal_title：Scientific reports

authors： Usuki F,Fujimura M,Yamashita A

更新日期：2017-09-28 00:00:00

abstract：:Empowering an indirect band-gap material like Si with optical functionalities, firstly light emission, represents a huge advancement constantly pursued in the realization of any integrated photonic device. We report the demonstration of giant photoluminescence (PL) emission by a newly synthesized material consisting o...

journal_title：Scientific reports

authors： Faraci G,Pennisi AR,Alberti A,Ruggeri R,Mannino G

更新日期：2013-01-01 00:00:00

abstract：:We compared the prognostic value of nutritional or volumetric parameters measured by body composition in hospitalized patients on maintenance hemodialysis. We conducted a cohort study to assess the association of different parameters of body composition with all-cause mortality in inpatients admitted to our nephrology...

journal_title：Scientific reports

authors： Wu B,Yan C,Zhang S,Ge Y,Xu X,Wang Y,Xu L,Zhang C,Huang Z,Ren H,Wu J,Xing C,Mao H

更新日期：2020-06-23 00:00:00

abstract：:Uveitis, the pathologic condition of inflammation of the uvea, frequently leads to severe vision loss and blindness. S100A8 is a calcium-binding protein which mainly expresses in granulocytes and monocytes and plays a prominent role in the regulation of inflammatory processes and immune response. Here, we determined t...

journal_title：Scientific reports

authors： Wang Y,Zhang Z,Zhang L,Li X,Lu R,Xu P,Zhang X,Dai M,Dai X,Qu J,Lu F,Chi Z

更新日期：2016-10-27 00:00:00

abstract：:Savant syndrome is a phenomenon whereby individuals with cognitive impairments have one or more outstanding abilities, inconsistent with their general intellectual functioning. Approximately 50% of savant individuals have autism spectrum disorder (ASD), and 10-30% of people with ASD have savant skills. To shed additio...

journal_title：Scientific reports

authors： Daniel E,Menashe I

更新日期：2020-02-10 00:00:00

abstract：:Photoluminescence and photomodulated reflectivity measurements of ZnOSe alloys are used to demonstrate a splitting of the valence band due to the band anticrossing interaction between localized Se states and the extended valence band states of the host ZnO matrix. A strong multiband emission associated with optical tr...

journal_title：Scientific reports

authors： Welna M,Baranowski M,Linhart WM,Kudrawiec R,Yu KM,Mayer M,Walukiewicz W

更新日期：2017-03-13 00:00:00

abstract：:Inner Mongolia cashmere goats, as an important part of animal husbandry production, play an important role in animal fiber industry. In recent years, scientific research has made a lot of explorations on the molecular regulation mechanism of hair follicle cycle growth, but few studies have been reported on the develop...

journal_title：Scientific reports

authors： Han W,Yang F,Wu Z,Guo F,Zhang J,Hai E,Shang F,Su R,Wang R,Wang Z,Liu Z,Zhao Y,Wang Z,Zhang Y,Li J

更新日期：2020-03-11 00:00:00

abstract：:Cisplatin is a highly effective anti-cancer chemotherapeutic agent; however, its clinical use is severely limited by serious side effects, of which nephrotoxicity is the most important. In this study, we investigated whether Qiong-Yu-Gao (QYG), a popular traditional Chinese medicinal formula described 840 years ago, e...

journal_title：Scientific reports

authors： Teng ZY,Cheng XL,Cai XT,Yang Y,Sun XY,Xu JD,Lu WG,Chen J,Hu CP,Zhou Q,Wang XN,Li SL,Cao P

更新日期：2015-10-29 00:00:00

abstract：:Animals that experience situations likely to induce negative emotions show changes in judgment associated with pessimism. Few studies have focused on whether animals express stable differences in pessimism and whether these differences are related to personality traits. The first aim of this study was to explore if da...

journal_title：Scientific reports

authors： Lecorps B,Weary DM,von Keyserlingk MAG

更新日期：2018-01-23 00:00:00

abstract：:Microbiologically Influenced Corrosion (MIC) is a serious problem in many industries because it causes huge economic losses. Due to its excellent resistance to chemical corrosion, 2707 hyper duplex stainless steel (2707 HDSS) has been used in the marine environment. However, its resistance to MIC was not experimentall...

journal_title：Scientific reports

authors： Li H,Zhou E,Zhang D,Xu D,Xia J,Yang C,Feng H,Jiang Z,Li X,Gu T,Yang K

更新日期：2016-02-05 00:00:00

abstract：:We study the change in magnetisation with paramagnetic Al addition in the CoFeNi0.5Cr0.5-Alx (x: 0, 0.5, 1, and 1.5) complex concentrated alloy. The compositions were developed utilising the Mulliken electronegativity and d-electron/atom ratio. Spherical FeCr rich nanoprecipitates are observed for X: 1.0 and 1.5 in an...

journal_title：Scientific reports

authors： Morley NA,Lim B,Xi J,Quintana-Nedelcos A,Leong Z

更新日期：2020-09-02 00:00:00

abstract：:The interaction of a mechanical oscillator with the operation actions and environment fields will give rise to the splitting of normal modes. In this study, we investigate the normal mode splitting behaviour of a moving-particles-pumped single-span clamped-hinged elastic homogeneous beam based on the proposed multi-oc...

journal_title：Scientific reports

authors： Sun Z

更新日期：2018-06-28 00:00:00

abstract：:Soils - constituting the largest terrestrial carbon pool - are vulnerable to climatic warming. Currently existing uncertainties regarding carbon fluxes within terrestrial systems can be addressed by studies of past carbon cycle dynamics and related climate change recorded in sedimentary successions. Here we show an ex...

journal_title：Scientific reports

authors： Pieńkowski G,Hodbod M,Ullmann CV

更新日期：2016-08-24 00:00:00

abstract：:CLN3 mutations cause the fatal neurodegenerative disorder, CLN3 Batten disease. The Cln3-/- mouse model displays characteristic features of the human disease including motor deficits. When mice received acidified drinking water (pH 2.5-2.9) instead of normal tap water (pH 8.4) for several generations, the motor skills...

journal_title：Scientific reports

authors： Johnson TB,Langin LM,Zhao J,Weimer JM,Pearce DA,Kovács AD

更新日期：2019-10-18 00:00:00

abstract：:It well-known that mental training improves skill performance. Here, we evaluated skill acquisition and consolidation after physical or motor imagery practice, by means of an arm pointing task requiring speed-accuracy trade-off. In the main experiment, we showed a significant enhancement of skill after both practices ...

journal_title：Scientific reports

authors： Ruffino C,Truong C,Dupont W,Bouguila F,Michel C,Lebon F,Papaxanthis C

更新日期：2021-01-27 00:00:00

abstract：:Spreading rumors on the Internet has become increasingly pervasive due to the proliferation of online social media. This paper investigates how rumors are amplified by a group of users who share similar interests or views, dubbed as an echo chamber. To this end, we identify and analyze 'rumor' echo chambers, each of w...

journal_title：Scientific reports

authors： Choi D,Chun S,Oh H,Han J,Kwon TT

更新日期：2020-01-15 00:00:00

abstract：:The side effects of cisplatin (CDDP), notably nephrotoxicity, greatly limited its use in clinical chemotherapy. HuangQi Injections (HI), a commonly used preparation of the well-known Chinese herbal medicine Astragali radix, appeared to be promising treatment for nephrotoxicity without compromising the anti-tumor activ...

journal_title：Scientific reports

authors： Li CY,Song HT,Wang XX,Wan YY,Ding XS,Liu SJ,Dai GL,Liu YH,Ju WZ

更新日期：2017-06-15 00:00:00

abstract：:Breast cancer is a heterogeneous disease consisting of several subtypes. Among these subtypes, triple negative breast cancer is particularly difficult to treat. This is due to a lack of understanding of the mechanisms behind the disease, and consequently a lack of druggable targets. PAK4 plays critical roles in cell s...

journal_title：Scientific reports

authors： Rane C,Senapedis W,Baloglu E,Landesman Y,Crochiere M,Das-Gupta S,Minden A

更新日期：2017-02-15 00:00:00

abstract：:This is the first study to investigate the impact of a second fibula flap or a soft tissue flap combined with bridging plate for a repeated segmental mandibulectomy reconstruction on flap outcomes in head and neck cancer patients. A retrospective comparative analysis (2007-2016) of 61 patients who underwent a second s...

journal_title：Scientific reports

authors： Lin JA,Loh CYY,Tsai CH,Chang KP,Wu JC,Kao HK

更新日期：2019-05-28 00:00:00

abstract：:Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within their genomic stru...

journal_title：Scientific reports

authors： Lam TH,Tay MZ,Wang B,Xiao Z,Ren EC

更新日期：2015-11-23 00:00:00

abstract：:Angiogenesis is a key restorative process following stroke but has also been linked to increased vascular permeability and blood brain barrier (BBB) disruption. Previous pre-clinical approaches primarily focused on the administration of vascular endothelial growth factor (VEGF) to promote vascular repair after stroke....

journal_title：Scientific reports

authors： Rust R,Weber RZ,Grönnert L,Mulders G,Maurer MA,Hofer AS,Sartori AM,Schwab ME

更新日期：2019-12-27 00:00:00

abstract：:Our study focused on quantifying the alterations of streamflow at a weir site due to the construction of a mini-hydropower plant in the Gurugoda Oya (Sri Lanka), and evaluating the spatial responses of benthic macroinvertebrates to altered flow regime. The HEC-HMS 3.5 model was applied to the Gurugoda Oya sub-catchmen...

journal_title：Scientific reports

authors： Munasinghe DSN,Najim MMM,Quadroni S,Musthafa MM

更新日期：2021-01-12 00:00:00

abstract：:Worldwide, Bartonella infections are known to inflict a wide range of mammals and, within rodents alone, more than 20 Bartonella species have been detected. There is, however, a lack of studies on the presence of Bartonella spp. in rodents in the Baltic region. We analysed 580 individuals belonging to eight small rode...

journal_title：Scientific reports

authors： Mardosaitė-Busaitienė D,Radzijevskaja J,Balčiauskas L,Bratchikov M,Jurgelevičius V,Paulauskas A

更新日期：2019-08-26 00:00:00

abstract：:Pulsed electromagnetic fields (PEMFs) have been considered a potential treatment modality for fracture healing, however, the mechanism of their action remains unclear. Mammalian target of rapamycin (mTOR) signaling may affect osteoblast proliferation and differentiation. This study aimed to assess the osteogenic diffe...

journal_title：Scientific reports

authors： Ferroni L,Gardin C,Dolkart O,Salai M,Barak S,Piattelli A,Amir-Barak H,Zavan B

更新日期：2018-03-23 00:00:00

abstract：:Ammonia-oxidizing archaea (AOA) are recently found to participate in the ammonia removal processes in wastewater treatment plants (WWTPs), similar to their bacterial counterparts. However, due to lack of cultivated AOA strains from WWTPs, their functions and contributions in these systems remain unclear. Here we repor...

journal_title：Scientific reports

authors： Li Y,Ding K,Wen X,Zhang B,Shen B,Yang Y

更新日期：2016-03-31 00:00:00

abstract：:Nanotechnology can improve the performance of dental polymers. The objective of this study was to modify the surfaces of nanoparticles with silanes and proteins, characterize nanoparticles' agglomeration levels and interfaces between nanoparticles and the polymeric matrix. Undoped (n-TiO2), nitrogen-doped (N_TiO2) and...

journal_title：Scientific reports

authors： Esteban Florez FL,Trofimov AA,Ievlev A,Qian S,Rondinone AJ,Khajotia SS

更新日期：2020-06-17 00:00:00

abstract：:Heart failure is the most common cause of morbidity and hospitalization in the western civilization. Protein phosphatases play a key role in the basal cardiac contractility and in the responses to β-adrenergic stimulation with type-1 phosphatase (PP-1) being major contributor. We propose here that formation of transie...

journal_title：Scientific reports

authors： Singh S,Lämmle S,Giese H,Kämmerer S,Meyer-Roxlau S,Alfar EA,Dihazi H,Guan K,El-Armouche A,Richter F

更新日期：2018-12-07 00:00:00

abstract：:The quest to 'forward-engineer' and fabricate biological machines remains a grand challenge. Towards this end, we have fabricated locomotive "bio-bots" from hydrogels and cardiomyocytes using a 3D printer. The multi-material bio-bot consisted of a 'biological bimorph' cantilever structure as the actuator to power the ...

journal_title：Scientific reports

authors： Chan V,Park K,Collens MB,Kong H,Saif TA,Bashir R

更新日期：2012-01-01 00:00:00

abstract：:The natural peptide chensinin-1 doesnot exhibit its desired biological properties. In this study, the mutant MC1-1 was designed by replacing Gly in the chensinin-1 sequence with Trp. Mutants MC1-2 and MC1-3 were designed based on the MC1-1 sequence to investigate the specific role of His residues. The mutated peptides...

journal_title：Scientific reports

authors： Dong W,Mao X,Guan Y,Kang Y,Shang D

更新日期：2017-01-05 00:00:00

abstract：:Developmental neurotoxic compounds impair the developing human nervous system at lower doses than those affecting adults. Standardized test methods for assessing developmental neurotoxicity (DNT) require the use of high numbers of laboratory animals. Here, we use a novel assay that is based on the development of an in...

journal_title：Scientific reports

authors： Bode K,Nolte L,Kamin H,Desens M,Ulmann A,Bergmann GA,Betker P,Reitmeier J,Ripken T,Stern M,Meyer H,Bicker G

更新日期：2020-02-14 00:00:00