Pulsed electromagnetic fields increase osteogenetic commitment of MSCs via the mTOR pathway in TNF-α mediated inflammatory conditions: an in-vitro study.

abstract：:Close contacts between the endoplasmic reticulum membrane and the mitochondrial outer membrane facilitate efficient transfer of lipids between the organelles and coordinate Ca2+ signalling and stress responses. Changes to this coupling is associated with a number of metabolic disorders and neurodegenerative diseases i...

journal_title：Scientific reports

authors： Harmon M,Larkman P,Hardingham G,Jackson M,Skehel P

更新日期：2017-12-12 00:00:00

abstract：:Leptin has a central role in the maintenance of energy homeostasis, and its sensitivity is influenced by both the photoperiod and dietary polyphenols. The aim of this study was to investigate the effect of seasonal consumption of polyphenol-rich fruits on the hypothalamic leptin signaling system in non-obese and obese...

journal_title：Scientific reports

authors： Ibars M,Aragonès G,Ardid-Ruiz A,Gibert-Ramos A,Arola-Arnal A,Suárez M,Bladé C

更新日期：2018-09-11 00:00:00

abstract：:We conducted two online surveys about antibiotics targeted at the Japanese general population in March 2017 and February 2018. In total, 6,982 participants completed the questionnaire. Factors associated with knowledge of antibiotics, knowledge of antimicrobial resistance (AMR) and appropriate behavioural changes were...

journal_title：Scientific reports

authors： Tsuzuki S,Fujitsuka N,Horiuchi K,Ijichi S,Gu Y,Fujitomo Y,Takahashi R,Ohmagari N

更新日期：2020-02-26 00:00:00

abstract：:Ratchet is a device that produces direct current of particles when driven by an unbiased force. We demonstrate a simple scattering quantum ratchet based on an asymmetrical quantum tunneling effect in two-dimensional electron gas with Rashba spin-orbit interaction (R2DEG). We consider the tunneling of electrons across ...

journal_title：Scientific reports

authors： Ang YS,Ma Z,Zhang C

更新日期：2015-01-19 00:00:00

abstract：:The rare-earth monopnictide family is attracting an intense current interest driven by its unusual extreme magnetoresistance (XMR) property and the potential presence of topologically non-trivial surface states. The experimental observation of non-trivial surface states in this family of materials are not ubiquitous. ...

journal_title：Scientific reports

authors： Hosen MM,Dhakal G,Wang B,Poudel N,Singh B,Dimitri K,Kabir F,Sims C,Regmi S,Neff W,Sarkar AB,Agarwal A,Murray D,Weickert F,Gofryk K,Pavlosiuk O,Wiśniewski P,Kaczorowski D,Bansil A,Neupane M

更新日期：2020-07-31 00:00:00

abstract：:Heparan sulfate (HS) is a polysaccharide known to modulate many important biological processes, including Wnt signaling. However, the biochemical interaction between HS and Wnt molecules is not well characterized largely due to the lack of suitable methods. To determine the Wnt binding domain in HS, we used a Wnt sign...

journal_title：Scientific reports

authors： Gao W,Xu Y,Liu J,Ho M

更新日期：2016-05-17 00:00:00

abstract：:Gene expression profiles reflect the biologically diverse activities of cells under specific cell environments. Using the transcriptional response of cultured cells to blood composition, we developed a litmus gene assay to discriminate blood samples reflecting different sample qualities or disease conditions. This cel...

journal_title：Scientific reports

authors： Shim SM,Kim JH,Jeon JP

更新日期：2017-12-04 00:00:00

abstract：:We have previously shown that OX40L/OX40 interaction is critical for TCR-independent selective proliferation of Foxp3+ Tregs, but not Foxp3- effector T-cells (Teff), when CD4+ T-cells are co-cultured with GM-CSF derived bone marrow dendritic cells (G-BMDCs). Events downstream of OX40L/OX40 interaction in Tregs respons...

journal_title：Scientific reports

authors： Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Bhattacharya P,Sun Z,Epstein AL,Maker AV,Prabhakar BS

更新日期：2017-07-26 00:00:00

abstract：:Cooperative behaviors are common in humans, and they are the fundamental basis of our society. Theoretical and experimental studies have modeled environments where the behaviors of humans, or agents, have been restricted to analyze their social behavior. However, it is important that such studies can be generalized to...

journal_title：Scientific reports

authors： Takano M,Wada K,Fukuda I

更新日期：2015-07-28 00:00:00

abstract：:Migraine headache is often timed with the menstrual cycle. Some studies have reported reduced risk of breast cancer in migraineurs but most of those did not distinguish menstrually-related from non-menstrually-related migraine. To examine the possible associations between breast cancer and migraine overall and between...

journal_title：Scientific reports

authors： Shi M,DeRoo LA,Sandler DP,Weinberg CR

更新日期：2015-10-12 00:00:00

abstract：:The control of structural and chemical transitions in bimetallic nanoalloys at finite temperatures is one of the challenges for their use in advanced applications. Comparing Nested Sampling and Molecular Dynamics simulations, we investigate the phase changes of CuPt nanoalloys with the aim to elucidate the role of kin...

journal_title：Scientific reports

authors： Rossi K,Pártay LB,Csányi G,Baletto F

更新日期：2018-06-14 00:00:00

abstract：:The present study investigated the treatment and survival outcomes of patients with synchronous primary esophageal squamous cell carcinoma and gastric adenocarcinoma. The medical records of 10,783 patients with primary esophageal squamous cancer treated at our institution between 1995 and 2012 were retrospectively rev...

journal_title：Scientific reports

authors： Li X,Lin S,Zhang Y,Wang H

更新日期：2015-08-20 00:00:00

abstract：:Although numerous reports on nonprecious metal catalysts for replacing expensive Pt-based catalysts have been published, few of these studies have demonstrated their practical application in fuel cells. In this work, we report graphitic carbon nitride and carbon nanofiber hybrid materials synthesized by a facile and g...

journal_title：Scientific reports

authors： Kim OH,Cho YH,Chung DY,Kim MJ,Yoo JM,Park JE,Choe H,Sung YE

更新日期：2015-03-02 00:00:00

abstract：:Many environmental flow (e-flow) studies and applications have predominantly used state-(i.e., at a single time point) and rate-(i.e., temporal change) based demographic characteristics of species representing lower trophic levels (e.g., fish communities) to build flow-ecology relationships, rather than using a proces...

journal_title：Scientific reports

authors： Paudel S,Koprowski JL,Thakuri U,Sigdel R,Gautam RC

更新日期：2020-12-18 00:00:00

abstract：:Estimates suggest that at least half of all extant insect genera harbor obligate bacterial mutualists. Whereas an endosymbiotic relationship imparts many benefits upon host and symbiont alike, the intracellular lifestyle has profound effects on the bacterial genome. The obligate endosymbiont genome is a product of opp...

journal_title：Scientific reports

authors： Alleman A,Hertweck KL,Kambhampati S

更新日期：2018-09-07 00:00:00

abstract：:The excessive release and accumulation of glutamate in the brain is known to be associated with excitotoxicity. CE, an extract derived from the plant Coeloglossum viride var. Bracteatum, exerted neuroprotective effects against amyloid toxicity and oxidative stress in cortical neurons. The aims of this study are to exa...

journal_title：Scientific reports

authors： Pan RY,Ma J,Wu HT,Liu QS,Qin XY,Cheng Y

更新日期：2017-08-23 00:00:00

abstract：:Transient ischemia produces postischemic tingling sensation. Ischemia also produces nerve conduction block that may modulate spinal neural circuits. In the present study, reduced mechanical thresholds for hindpaw-withdrawal reflex were found in mice after transient hindpaw ischemia, which was produced by a high pressu...

journal_title：Scientific reports

authors： Watanabe T,Sasaki M,Komagata S,Tsukano H,Hishida R,Kohno T,Baba H,Shibuki K

更新日期：2015-07-13 00:00:00

abstract：:The objective of this study was to evaluate the stimulatory effects of Bacillus amyloliquefaciens SQR9 on dendritic cells (DCs) and to verify its ability to enhance the immune response by modulating DC maturation. The results demonstrated that B. amyloliquefaciens SQR9 can adhere to the nasal epithelium and be taken u...

journal_title：Scientific reports

authors： Huang L,Qin T,Yin Y,Gao X,Lin J,Yang Q,Yu Q

更新日期：2016-02-19 00:00:00

abstract：:Lung adenosquamous cell carcinomas (ASCs) is a rare variant of NSCLC with a poorer prognosis and fewer treatment option than the more common variants. PD-L1 expression is reported to be the predictor of clinical response in trials of NSCLC. In our study, PD-L1 expression was evaluated via immunohistochemistry using a ...

journal_title：Scientific reports

authors： Shi X,Wu S,Sun J,Liu Y,Zeng X,Liang Z

更新日期：2017-04-07 00:00:00

abstract：:This study aimed to determine the clinicopathological features of the subtypes of ampullary carcinoma (AC) to explore the indications for endoscopic papillectomy (EP) in early AC. Fifty-seven patients with AC who underwent curative resection were retrospectively reviewed. The 0/IA stages were significantly more common...

journal_title：Scientific reports

authors： Yamamoto K,Itoi T,Nagata N,Sofuni A,Tsuchiya T,Ishii K,Tanaka R,Tonozuka R,Honjo M,Mukai S,Asai Y,Matsunami Y,Yamaguchi H,Matsubayashi J,Joyama E,Nagakawa Y

更新日期：2021-01-12 00:00:00

abstract：:MDN1/Rea1, as an AAA-type ATPase, is predicted to be the largest protein involved in pre-ribosome maturation in most organisms. However, its function in plant growth and development is poorly understood. Here, we characterized a novel Arabidopsis mutant, dwarf &short root (dsr) 1, which shows pleiotropic developmental...

journal_title：Scientific reports

authors： Li PC,Yu SW,Li K,Huang JG,Wang XJ,Zheng CC

更新日期：2016-11-08 00:00:00

abstract：:Tumor progression, limited efficacy of current standard treatments, and the rise in patient mortality are associated with gene expression caused by the synergistic action of intratumoral hypoxia and HIF-1α activation. For this reason, recent investigations have focused on HIF-targeting therapeutic agents, with encoura...

journal_title：Scientific reports

authors： Mangraviti A,Raghavan T,Volpin F,Skuli N,Gullotti D,Zhou J,Asnaghi L,Sankey E,Liu A,Wang Y,Lee DH,Gorelick N,Serra R,Peters M,Schriefer D,Delaspre F,Rodriguez FJ,Eberhart CG,Brem H,Olivi A,Tyler B

更新日期：2017-11-02 00:00:00

abstract：:Chromosomal toxin-antitoxin (TA) systems are widespread genetic elements among bacteria, yet, despite extensive studies in the last decade, their biological importance remains ambivalent. The ability of TA-encoded toxins to affect stress tolerance when overexpressed supports the hypothesis of TA systems being associat...

journal_title：Scientific reports

authors： Rosendahl S,Tamman H,Brauer A,Remm M,Hõrak R

更新日期：2020-06-08 00:00:00

abstract：:The subjective experience of thermal pain follows the detection and encoding of noxious stimuli by primary afferent neurons called nociceptors. However, nociceptor morphology has been hard to access and the mechanisms of signal transduction remain unresolved. In order to understand how heat transducers in nociceptors ...

journal_title：Scientific reports

authors： Dezhdar T,Moshourab RA,Fründ I,Lewin GR,Schmuker M

更新日期：2015-12-07 00:00:00

abstract：:Anatomical features of first maxillary premolars may greatly affect endodontic and following restorative treatments. The aim of this study was to evaluate root canal configuration and root wall thickness of first maxillary premolars using a preexisting CBCT database. A CBCT database of 400 first maxillary premolar was...

journal_title：Scientific reports

authors： Kfir A,Mostinsky O,Elyzur O,Hertzeanu M,Metzger Z,Pawar AM

更新日期：2020-01-16 00:00:00

abstract：:Halogen bonding between a carbazole-based, pyridine-substituted organic semiconductor and a common halogen-bond donor (pentafluoroiodobenzene) yields efficient halogen-bond-driven fluorescence modulation in solution. Steady-state, time-resolved emission and absorption spectroscopy as well as density functional theory ...

journal_title：Scientific reports

authors： Salunke JK,Durandin NA,Ruoko TP,Candeias NR,Vivo P,Vuorimaa-Laukkanen E,Laaksonen T,Priimagi A

更新日期：2018-09-26 00:00:00

abstract：:In this study, the biocompatibility and in vitro degradation behaviour of a commercial zinc-based alloy (Zn-5 Al-4 Mg) were evaluated and compared with that of pure zinc for temporary orthopaedic implant applications. Biocompatibility tests were conducted using human alveolar lung epithelial cells (A549), which showed...

journal_title：Scientific reports

authors： Kannan MB,Moore C,Saptarshi S,Somasundaram S,Rahuma M,Lopata AL

更新日期：2017-11-15 00:00:00

abstract：:The Dirac materials, such as graphene and three-dimensional topological insulators, have attracted much attention because they exhibit novel quantum phenomena with their low energy electrons governed by the relativistic Dirac equations. One particular interest is to generate Dirac cone anisotropy so that the electrons...

journal_title：Scientific reports

authors： Feng Y,Wang Z,Chen C,Shi Y,Xie Z,Yi H,Liang A,He S,He J,Peng Y,Liu X,Liu Y,Zhao L,Liu G,Dong X,Zhang J,Chen C,Xu Z,Dai X,Fang Z,Zhou XJ

更新日期：2014-06-20 00:00:00

abstract：:To determine whether any brain MR abnormalities, including enlarged perivascular spaces (EPVS), were associated with disease activity in systemic lupus erythematosus (SLE) as an inflammatory activity. One hundred and thirty SLE patients with normal MR findings were assessed. With regard to MRI abnormalities, patients ...

journal_title：Scientific reports

authors： Miyata M,Kakeda S,Iwata S,Nakayamada S,Ide S,Watanabe K,Moriya J,Tanaka Y,Korogi Y

更新日期：2017-10-03 00:00:00

abstract：:IFI16 and AIM2 are important DNA sensors in antiviral immunity. To characterize these two molecules in a woodchuck model, which is widely used to study hepatitis B virus (HBV) infection, we cloned and analyzed the complete coding sequences (CDSs) of woodchuck IFI16 and AIM2, and found that AIM2 was highly conserved in...

journal_title：Scientific reports

authors： Yan Q,Li M,Liu Q,Li F,Zhu B,Wang J,Lu Y,Liu J,Wu J,Zheng X,Lu M,Wang B,Yang D

更新日期：2016-06-29 00:00:00