Abstract:
:This is the first study to investigate the impact of a second fibula flap or a soft tissue flap combined with bridging plate for a repeated segmental mandibulectomy reconstruction on flap outcomes in head and neck cancer patients. A retrospective comparative analysis (2007-2016) of 61 patients who underwent a second segmental mandibulectomy was performed. 20 patients underwent a fibula flap reconstruction whereas 41 had a soft tissue flap and plate reconstruction. No significant difference was seen in the operative time, total hospital stay, flap loss, re-exploration rates, plate exposure rate, or recipient site infection rate. On multivariate analysis, patients reconstructed with a soft tissue flap and bridging plate (odds ratio (OR) 3.997; 95% confidence interval (CI), 1.046-15.280, p = 0.043) and complications developed in previous surgery (OR 4.792; 95% CI, 1.120-20.493, p = 0.035) were shown to be independent predictors of a prolonged nasogastric tube dependence. The utilization of a soft tissue flap with plate is associated with comparative results of acute complication rate within 1 week, recipient site infection rate, and plate exposure rate to free fibula flaps alone. Free fibula flaps may result in a decreased risk for prolonged tube dependence compared to free soft tissue flap reconstructions.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lin JA,Loh CYY,Tsai CH,Chang KP,Wu JC,Kao HKdoi
10.1038/s41598-019-44467-xsubject
Has Abstractpub_date
2019-05-28 00:00:00pages
7951issue
1issn
2045-2322pii
10.1038/s41598-019-44467-xjournal_volume
9pub_type
杂志文章abstract::Collagen, the dominating material in the extracellular matrix, provides the strength, elasticity and mechanical stability to the organisms. The mechanical property of collagen is mainly dominated by its surrounding environments. However, the variation and origin of the mechanics of collagen fibril under different conc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46042
更新日期:2017-04-05 00:00:00
abstract::Water-soluble protein content (WSPC) is a critical factor in both soybean protein quality and functionality. However, the underlying genetic determinants are unclear. Here, we used 219 soybean accessions and 152 recombinant inbred lines genotyped with high-density markers and phenotyped in multi-environments to dissec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04685-7
更新日期:2017-07-11 00:00:00
abstract::Changes associated with cognitive function in the high-fat high-carbohydrate diet-induced prediabetes animal model and effect of exercise remain unclear. Rats were randomly assigned to the following groups (n = 6): non-diabetic (ND), prediabetic (PD), intermittent exercising PD (PD + IE) and regular exercising PD (PD ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72098-0
更新日期:2020-09-14 00:00:00
abstract::In this study, a rational combination of 200 pre-selected Carbohydrate-Active enzymes (CAZymes) and sulfatases were tested, individually or combined, according to their ability to degrade Chlorella vulgaris cell wall to access its valuable nutritional compounds. The disruption of microalgae cell walls by a four-enzyme...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41775-0
更新日期:2019-03-29 00:00:00
abstract::The aim of this study was to fabricate a novel polymer-free everolimus-eluting stent with nanostructure using a femtosecond laser (FSL). The stent were coated with everolimus (EVL) using FSL and electrospinning processes. The surface was rendered hydrophobic, which negatively affected both platelet adhesion (82.1%) an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25629-9
更新日期:2018-05-09 00:00:00
abstract::Autophagy is a lysosomal degradation pathway that plays an essential role in neuronal homeostasis and is perturbed in many neurological diseases. Transcriptional downregulation of fat was previously observed in a Drosophila model of the polyglutamine disease Dentatorubral-pallidoluysian atrophy (DRPLA) and this was sh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52684-7
更新日期:2019-11-06 00:00:00
abstract::In this study, we reported a new technique based on laser speckle flowgraphy to record the ocular blood flow in rabbits under deep anesthesia, and proposed parameters to characterize retinal ischemia. We applied the proposed technique to study the correlation of blood flow between the eyes of normal non-anesthetized a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24141-4
更新日期:2018-04-09 00:00:00
abstract::In this paper, we present a strategy to improve delivery of femtosecond laser pulses from a regenerative amplifier through a hollow core photonic crystal fiber for temporally focused wide-field two-photon endomicroscopy. For endomicroscope application, wide-field two-photon excitation has the advantage of requiring no...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06626
更新日期:2014-10-15 00:00:00
abstract::MircoRNA's (miR) have been recognised as important modulators of gene expression and potential biomarkers. However, they have been rarely investigated in bio fluids apart from blood. We investigated the association of miR-125b and miR-155 with complications of cirrhosis. Ascites was prospectively collected from patien...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40556
更新日期:2017-01-11 00:00:00
abstract::Understanding the molecular mechanism by which epithelial mesenchymal transition (EMT)-mediated cancer metastasis and how microRNA (miRNA) regulates lung cancer progression via Twist1-activated EMT may provide potential therapeutic targets for cancer therapy. Here we found that miR-33a, an intronic miRNA located withi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13677
更新日期:2015-09-02 00:00:00
abstract::The biliary tree is an essential component of transplantable human liver tissue. Despite recent advances in liver tissue engineering, attempts at re-creating the intrahepatic biliary tree have not progressed significantly. The finer branches of the biliary tree are structurally and functionally complex and heterogeneo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30433-6
更新日期:2018-08-15 00:00:00
abstract::The understanding of the relationship between topology and behaviour in interconnected networks would allow to charac- terise and predict behaviour in many real complex networks since both are usually not simultaneously known. Most previous studies have focused on the relationship between topology and synchronisation....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22617
更新日期:2016-03-04 00:00:00
abstract::Hypothermic oxygenated machine perfusion (HOPE) was introduced in liver transplantation (LT) to mitigate ischemia-reperfusion injury. Available clinical data mainly concern LT with donors after circulatory-determined death, whereas data on brain-dead donors (DBD) are scarce. To assess the impact of end-ischemic HOPE i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45843-3
更新日期:2019-06-27 00:00:00
abstract::Desert locusts (Schistocerca gregaria) show a dramatic form of socially induced phenotypic plasticity known as phase polyphenism. In the absence of conspecifics, locusts occur in a shy and cryptic solitarious phase. Crowding with conspecifics drives a behavioural transformation towards gregariousness that occurs withi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35608
更新日期:2016-10-18 00:00:00
abstract::There are only few studies that explore the ecological consequences of forest management on several organism groups. We studied the short-term effects of four forestry treatments including preparation cutting, clear-cutting, retention tree group and gap-cutting in a temperate managed forest on the assemblage structure...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35159-z
更新日期:2018-11-19 00:00:00
abstract::We present a model on the simulation of the measurement-device independent quantum key distribution (MDI-QKD) with phase randomized general sources. It can be used to predict experimental observations of a MDI-QKD with linear channel loss, simulating corresponding values for the gains, the error rates in different bas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04612
更新日期:2014-04-14 00:00:00
abstract::We report on the magnetic field control of a bipolar resistive switching in Ag/TiO2/FTO based resistive random access memory device through I-V characteristics. Essentially, in the presence of magnetic field and in the low resistance state, an abrupt change in the resistance of the device demands higher voltage, hinti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17607-4
更新日期:2017-12-08 00:00:00
abstract::The competitive multi-armed bandit (CMAB) problem is related to social issues such as maximizing total social benefits while preserving equality among individuals by overcoming conflicts between individual decisions, which could seriously decrease social benefits. The study described herein provides experimental evide...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48647-7
更新日期:2019-08-22 00:00:00
abstract::The extraction of renewable energy resources particularly from earth abundant materials has always been a matter of significance in industrial products. Herein, we report a novel simultaneous extraction of nano-silicon with activated carbons (nano-Si@ACs) from rice husk (RH) by chemical activation method. As-extracted...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39314
更新日期:2016-12-21 00:00:00
abstract::Multinational corporations use highly complex structures of parents and subsidiaries to organize their operations and ownership. Offshore Financial Centers (OFCs) facilitate these structures through low taxation and lenient regulation, but are increasingly under scrutiny, for instance for enabling tax avoidance. There...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06322-9
更新日期:2017-07-24 00:00:00
abstract::Conventional crystalline β-MnO2 usually exhibits poor electrochemical activities due to the narrow tunnels in its rutile-type structure. In this study, we synthesized a novel 2D β-MnO2 network with long-range order assembled by β-MnO2 nanowires and demonstrated that the novel 2D β-MnO2 network exhibits enhanced electr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02193
更新日期:2013-01-01 00:00:00
abstract::Neovascularization of the erectile tissue emerges as a beneficial curative approach to treat erectile dysfunction (ED). Here we for the first time report the unexpected role of vasohibin-1 (VASH1), mainly known as an anti-angiogenic factor, in restoring erectile function in diabetic mice. A diabetic patient has lower ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80925-7
更新日期:2021-01-13 00:00:00
abstract::The overall light energy to biomass conversion efficiency of plant photosynthesis is generally regarded as low. Forward genetic screens in Arabidopsis have yielded very few mutants with substantially enhanced photochemistry. Here, we report the isolation of a novel Arabidopsis mutant with a high operating efficiency o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03611-1
更新日期:2017-06-12 00:00:00
abstract::Surface incident solar radiation (Rs) of reanalysis products is widely used in ecological conservation, agricultural production, civil engineering and various solar energy applications. It is of great importance to have a good knowledge of the uncertainty of reanalysis Rs products. In this study, we evaluated the Rs e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60460-1
更新日期:2020-02-26 00:00:00
abstract:ABSTARCT:The stability and reactivity of clusters are closely related to their valence electronic configuration. Doping is a most efficient method to modify the electronic configuration and properties of a cluster. Considering that Cu and S posses one and six valence electrons, respectively, the S doped Cu clusters wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01444-6
更新日期:2017-05-02 00:00:00
abstract::The association between maternal cadmium (Cd) exposure during pregnancy and the increased risk of fetal growth restriction (FGR) remains controversial. The present study evaluated the association between maternal serum Cd level and risk of small for gestational age (SGA) infants in a Chinese population. The present st...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1038/srep22631
更新日期:2016-03-03 00:00:00
abstract::Circadian clocks are endogenous oscillators driving daily rhythms in physiology. The cell-autonomous clock is governed by an interlocked network of transcriptional feedback loops. Hundreds of clock-controlled genes (CCGs) regulate tissue specific functions. Transcriptome studies reveal that different organs (e.g. live...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05782
更新日期:2014-07-22 00:00:00
abstract::Although optimal therapy for myocardial infarction includes reperfusion to restore blood flow to the ischemic region, ischemia/reperfusion (IR) also initiates an inflammatory response likely contributing to adverse left ventricular (LV) extracellular matrix (ECM) remodeling. Galectin-3 (Gal-3), a β-galactoside-binding...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46119-6
更新日期:2019-07-03 00:00:00
abstract::We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mφs). Non-alcoholic steatohepatitis (NASH) is characterized not only by hepatic steatosis but also chronic inflammation and fibrosis. In the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34466
更新日期:2016-10-06 00:00:00
abstract::Geriatric trauma is a major socio-economic problem, especially among the aging Japanese society. Geriatric people are more vulnerable to trauma than younger people; thus, their outcomes are often severe. This study evaluates the characteristics of geriatric trauma divided by age in the Japanese population. We evaluate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76149-4
更新日期:2020-11-05 00:00:00