Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins.

abstract：:While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs in magnetic sorted IgM+ cell...

journal_title：Scientific reports

authors： Jenberie S,Thim HL,Sunyer JO,Skjødt K,Jensen I,Jørgensen JB

更新日期：2018-02-23 00:00:00

abstract：:Here, we report direct band gap transition for Gallium Phosphide (GaP) when alloyed with just 1-2 at% antimony (Sb) utilizing both density functional theory based computations and experiments. First principles density functional theory calculations of GaSbxP(1-x) alloys in a 216 atom supercell configuration indicate t...

journal_title：Scientific reports

authors： Russell HB,Andriotis AN,Menon M,Jasinski JB,Martinez-Garcia A,Sunkara MK

更新日期：2016-02-10 00:00:00

abstract：:Diabetes mellitus (DM) significantly increases myocardial ischemia/reperfusion (MI/R) injury. During DM, cardioprotection induced by conventional pre-conditioning (PreCon) is decreased due to impaired AMP-activated protein kinase (AMPK) signaling. The current study investigated whether PreCon with inhaled anesthetic s...

journal_title：Scientific reports

authors： Xie D,Zhao J,Guo R,Jiao L,Zhang Y,Lau WB,Lopez B,Christopher T,Gao E,Cao J,Ma X,Wang Y

更新日期：2020-01-08 00:00:00

abstract：:Accurate alignment of an intraocular lens (IOL) is indispensable for achieving accurate postoperative refractive outcomes. Thus, we evaluated decentration and tilt of single- and three-piece IOLs, as well as anterior chamber depth (ACD), at 3 hours, 24 hours, 2 weeks, and 4 weeks after cataract surgery, using swept-so...

journal_title：Scientific reports

authors： Sato T,Shibata S,Yoshida M,Hayashi K

更新日期：2018-07-06 00:00:00

abstract：:We propose a deep learning model - Probabilistic Prognostic Estimates of Survival in Metastatic Cancer Patients (PPES-Met) for estimating short-term life expectancy (>3 months) of the patients by analyzing free-text clinical notes in the electronic medical record, while maintaining the temporal visit sequence. In a si...

journal_title：Scientific reports

authors： Banerjee I,Gensheimer MF,Wood DJ,Henry S,Aggarwal S,Chang DT,Rubin DL

更新日期：2018-07-03 00:00:00

abstract：:Tobacco hairy root (HR) cultures, which have been widely used for the heterologous production of target compounds, have an innate capacity to bioconvert exogenous t-resveratrol (t-R) into t-piceatannol (t-Pn) and t-pterostilbene (t-Pt). We established genetically engineered HR carrying the gene encoding stilbene synth...

journal_title：Scientific reports

authors： Hidalgo D,Georgiev M,Marchev A,Bru-Martínez R,Cusido RM,Corchete P,Palazon J

更新日期：2017-12-21 00:00:00

abstract：:Many outbreaks of A(H1N1)pdm09 influenza have occurred in schools with a high population density. Containment of school outbreaks is predicted to help mitigate pandemic influenza. Understanding disease transmission characteristics within the school setting is critical to implementing effective control measures. Based ...

journal_title：Scientific reports

authors： Wang L,Chu C,Yang G,Hao R,Li Z,Cao Z,Qiu S,Li P,Wu Z,Yuan Z,Xu Y,Zeng D,Wang Y,Song H

更新日期：2014-08-07 00:00:00

abstract：:The adipokines chemerin and omentin-1 have been suggested to influence cardiovascular function. The study aimed to investigate the longitudinal association between chemerin, omentin-1 concentrations and risk of incident heart failure (HF), respectively. We conducted a case-cohort study nested within the European Prosp...

journal_title：Scientific reports

authors： Menzel J,di Giuseppe R,Biemann R,Wittenbecher C,Aleksandrova K,Eichelmann F,Fritsche A,Schulze MB,Boeing H,Isermann B,Weikert C

更新日期：2017-10-26 00:00:00

abstract：:The impact of environment on individuals is particularly critical. In evolutionary games, adopting the strategy of the neighbor who performs better is nontrivial for the survival and maintenance of cooperation, in that such an action may help the agents to obtain higher benefit and more obvious evolutionary advantages...

journal_title：Scientific reports

authors： Wu Y,Zhang S,Zhang Z

更新日期：2018-10-23 00:00:00

abstract：:In this paper, we present a strategy to improve delivery of femtosecond laser pulses from a regenerative amplifier through a hollow core photonic crystal fiber for temporally focused wide-field two-photon endomicroscopy. For endomicroscope application, wide-field two-photon excitation has the advantage of requiring no...

journal_title：Scientific reports

authors： Choi H,So PT

更新日期：2014-10-15 00:00:00

abstract：:Predation plays a central role in the lives of most organisms. Predators must find and subdue prey to survive and reproduce, whereas prey must avoid predators to do the same. The resultant antagonistic coevolution often leads to extreme adaptations in both parties. Few examples capture the imagination like a rapid str...

journal_title：Scientific reports

authors： Higham TE,Clark RW,Collins CE,Whitford MD,Freymiller GA

更新日期：2017-01-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Dainese E,Oddi S,Simonetti M,Sabatucci A,Angelucci CB,Ballone A,Dufrusine B,Fezza F,De Fabritiis G,Maccarrone M

更新日期：2020-03-31 00:00:00

abstract：:Enterococcus faecalis, an organism generally not pathogenic for healthy humans, has the potential to cause disease in susceptible hosts. While it seems to be equipped to interact with and circumvent host immune defense, most of the molecular and cellular mechanisms underlying the enterococcal infectious process remain...

journal_title：Scientific reports

authors： Nunez N,Derré-Bobillot A,Gaubert S,Herry JM,Deschamps J,Wei Y,Baranek T,Si-Tahar M,Briandet R,Serror P,Archambaud C

更新日期：2018-01-29 00:00:00

abstract：:Poor oral health is not only associated with diabetes and cardiovascular disease but adverse pregnancy outcomes. However the influence of dental caries on pregnancy is unknown. The aim of this study was to evaluate the association between dental caries and adverse pregnancy outcomes and the effect of treatment for den...

journal_title：Scientific reports

authors： Cho GJ,Kim SY,Lee HC,Kim HY,Lee KM,Han SW,Oh MJ

更新日期：2020-03-24 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) affects over 30% of adults in the United States. Bone morphogenetic protein (BMP) signaling is known to contribute to hepatic fibrosis, but the role of BMP signaling in the development of NAFLD is unclear. In this study, treatment with either of two BMP inhibitors reduced hepa...

journal_title：Scientific reports

authors： Thayer TE,Lino Cardenas CL,Martyn T,Nicholson CJ,Traeger L,Wunderer F,Slocum C,Sigurslid H,Shakartzi HR,O'Rourke C,Shelton G,Buswell MD,Barnes H,Neitzel LR,Ledsky CD,Li JP,Burke MF,Farber-Eger E,Perrien DS,Kumar R,

更新日期：2020-06-19 00:00:00

abstract：:We report a novel method to fabricate high quality 2-inch freestanding GaN substrate grown on cross-stacked carbon nanotubes (CSCNTs) coated sapphire by hydride vapor phase epitaxy (HVPE). As nanoscale masks, these CSCNTs can help weaken the interface connection and release the compressive stress by forming voids duri...

journal_title：Scientific reports

authors： Wei T,Yang J,Wei Y,Huo Z,Ji X,Zhang Y,Wang J,Li J,Fan S

更新日期：2016-06-24 00:00:00

abstract：:Quantum key distribution involving decoy-states is a significant application of quantum information. By using three-intensity decoy-states of single-photon-added coherent sources, we propose a practically realizable scheme on quantum key distribution which approaches very closely the ideal asymptotic case of an infini...

journal_title：Scientific reports

authors： Wang D,Li M,Guo GC,Wang Q

更新日期：2015-10-14 00:00:00

abstract：:In this report, a hand-held impulse-radar breast cancer detector is presented and the detectability of malignant breast tumors is demonstrated in the clinical test at Hiroshima University Hospital, Hiroshima, Japan. The core functional parts of the detector consist of 65-nm technology complementary metal-oxide-semicon...

journal_title：Scientific reports

authors： Song H,Sasada S,Kadoya T,Okada M,Arihiro K,Xiao X,Kikkawa T

更新日期：2017-11-27 00:00:00

abstract：:The irritant receptor TRPA1 was suggested to mediate analgesic, antipyretic but also pro-inflammatory effects of the non-opioid analgesic acetaminophen, presumably due to channel activation by the reactive metabolites parabenzoquinone (pBQ) and N-acetyl-parabenzoquinonimine (NAPQI). Here we explored the effects of the...

journal_title：Scientific reports

authors： Eberhardt MJ,Schillers F,Eberhardt EM,Risser L,de la Roche J,Herzog C,Echtermeyer F,Leffler A

更新日期：2017-10-06 00:00:00

abstract：:The autoimmune disorder Aicardi-Goutières syndrome (AGS) is characterized by a constitutive type I interferon response. SAMHD1 possesses both dNTPase and RNase activities and mutations in SAMHD1 cause AGS; however, how SAMHD1-deficiency causes the type I interferon response in patients with AGS remains unknown. Here, ...

journal_title：Scientific reports

authors： Oh C,Ryoo J,Park K,Kim B,Daly MB,Cho D,Ahn K

更新日期：2018-01-08 00:00:00

abstract：:For one-dimensional (1d) nonlinear atomic lattices, the models with on-site nonlinearities such as the Frenkel-Kontorova (FK) and ϕ4 lattices have normal energy transport while the models with inter-site nonlinearities such as the Fermi-Pasta-Ulam-β (FPU-β) lattice exhibit anomalous energy transport. The 1d Discrete N...

journal_title：Scientific reports

authors： Li S,Li N

更新日期：2018-03-28 00:00:00

abstract：:Solar cells based on epitaxial silicon layers as the absorber attract increasing attention because of the potential cost reduction. In this work, we studied the influence of the deposition rate on the structural properties of epitaxial silicon layers produced by plasma-enhanced chemical vapor deposition (epi-PECVD) us...

journal_title：Scientific reports

authors： Chen W,Cariou R,Hamon G,Léal R,Maurice JL,Cabarrocas PR

更新日期：2017-03-06 00:00:00

abstract：:Many animals use sounds produced by conspecifics for mate identification. Female insects and anuran amphibians, for instance, use acoustic cues to localize, orient toward and approach conspecific males prior to mating. Here we present a novel technique that utilizes multiple, distributed sound-indication devices and a...

journal_title：Scientific reports

authors： Aihara I,Bishop PJ,Ohmer MEB,Awano H,Mizumoto T,Okuno HG,Narins PM,Hero JM

更新日期：2017-09-05 00:00:00

abstract：:Cassava is one of the most important root crops as a reliable source of food and carbohydrates. Carbohydrate metabolism and starch accumulation in cassava storage root is a cascade process that includes large amounts of proteins and cofactors. Here, comparative proteomics were conducted in cassava root at nine develop...

journal_title：Scientific reports

authors： Wang X,Chang L,Tong Z,Wang D,Yin Q,Wang D,Jin X,Yang Q,Wang L,Sun Y,Huang Q,Guo A,Peng M

更新日期：2016-01-21 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are glutamate- and glycine-gated channels composed of two GluN1 and two GluN2 or/and GluN3 subunits. GluN3A expression is developmentally regulated, and changes in this normal pattern of expression, which occur in several brain disorders, alter synaptic maturation and function by ...

journal_title：Scientific reports

authors： Cummings KA,Popescu GK

更新日期：2016-03-22 00:00:00

abstract：:We developed a simple, scalable and high-throughput method for fabrication of large-area three-dimensional rose-like microflowers with controlled size, shape and density on graphene films by femtosecond laser micromachining. The novel biomimetic microflower that composed of numerous turnup graphene nanoflakes can be f...

journal_title：Scientific reports

authors： Shi X,Li X,Jiang L,Qu L,Zhao Y,Ran P,Wang Q,Cao Q,Ma T,Lu Y

更新日期：2015-11-30 00:00:00

abstract：:Synthesis of homogenous glycans in quantitative yields represents a major bottleneck to the production of molecular tools for glycoscience, such as glycan microarrays, affinity resins, and reference standards. Here, we describe a combined biological/enzymatic synthesis that is capable of efficiently converting microbi...

journal_title：Scientific reports

authors： Hamilton BS,Wilson JD,Shumakovich MA,Fisher AC,Brooks JC,Pontes A,Naran R,Heiss C,Gao C,Kardish R,Heimburg-Molinaro J,Azadi P,Cummings RD,Merritt JH,DeLisa MP

更新日期：2017-11-21 00:00:00

abstract：:Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1), located in mitochondria, can recognize cytoplasmic pattern recognition receptors and is tightly related to reactive oxygen species (ROS) production, mitochondrial function, apoptosis and inflammation. The present study was designed ...

journal_title：Scientific reports

authors： Yin H,Sun G,Yang Q,Chen C,Qi Q,Wang H,Li J

更新日期：2017-03-13 00:00:00

abstract：:Previous studies have established that an increased Th-9 response creates a hostile environment for nematode parasites. Given that IL-23, a cytokine required for maintenance of the IL-17-secreting phenotype, has inhibitory effects on IL-9 production, we hypothesized that reducing circulating IL-23 by treatment with an...

journal_title：Scientific reports

authors： Gomez-Samblas M,Bernal D,Bolado-Ortiz A,Vilchez S,Bolás-Fernández F,Espino AM,Trelis M,Osuna A

更新日期：2018-05-17 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is the only blood based protein biomarker at present, used for preoperative screening of advanced colorectal cancer (CRC) patients to determine the appropriate curative treatments and post-surveillance screening for tumour recurrence. Current diagnostics for CRC detection have several li...

journal_title：Scientific reports

authors： Shamsuddin SH,Jayne DG,Tomlinson DC,McPherson MJ,Millner PA

更新日期：2021-01-12 00:00:00