Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.

abstract：:The description of ultrafast nonadiabatic chemical dynamics during molecular photo-transformations remains challenging because electronic and nuclear configurations impact each other and cannot be treated independently. Here we gain experimental insights, beyond the Born-Oppenheimer approximation, into the light-induc...

journal_title：Nature communications

authors： Lemke HT,Kjær KS,Hartsock R,van Driel TB,Chollet M,Glownia JM,Song S,Zhu D,Pace E,Matar SF,Nielsen MM,Benfatto M,Gaffney KJ,Collet E,Cammarata M

更新日期：2017-05-24 00:00:00

abstract：:Protein integration into biological membranes is a vital cellular event for all organisms. We previously reported an integration factor in the inner membrane of Escherichia coli, named MPIase (membrane protein integrase). Here we show that in contrast to previously identified integration factors that are proteins, MPI...

journal_title：Nature communications

authors： Nishiyama K,Maeda M,Yanagisawa K,Nagase R,Komura H,Iwashita T,Yamagaki T,Kusumoto S,Tokuda H,Shimamoto K

更新日期：2012-01-01 00:00:00

abstract：:Carbon and hydrogen are fundamental components of organic molecules and a fascinating plethora of functions can be generated using these two elements. Yet, realizing attractive electronic structures only by using carbon and hydrogen remains challenging. Herein, we report the synthesis and properties of the C70 fragmen...

journal_title：Nature communications

authors： Tanaka Y,Fukui N,Shinokubo H

更新日期：2020-08-03 00:00:00

abstract：:Optogenetics enables manipulation of biological processes with light at high spatio-temporal resolution to control the behavior of cells, networks, or even whole animals. In contrast to the performance of excitatory rhodopsins, the effectiveness of inhibitory optogenetic tools is still insufficient. Here we report a t...

journal_title：Nature communications

authors： Bernal Sierra YA,Rost BR,Pofahl M,Fernandes AM,Kopton RA,Moser S,Holtkamp D,Masala N,Beed P,Tukker JJ,Oldani S,Bönigk W,Kohl P,Baier H,Schneider-Warme F,Hegemann P,Beck H,Seifert R,Schmitz D

更新日期：2018-11-05 00:00:00

abstract：:The quantum noise of the vacuum limits the achievable sensitivity of quantum sensors. In non-classical measurement schemes the noise can be reduced to overcome this limitation. However, schemes based on squeezed or Schrödinger cat states require alignment of the relative phase between the measured interaction and the ...

journal_title：Nature communications

authors： Wolf F,Shi C,Heip JC,Gessner M,Pezzè L,Smerzi A,Schulte M,Hammerer K,Schmidt PO

更新日期：2019-07-02 00:00:00

abstract：:Integrin αVβ8, which like αVβ6 functions to activate TGF-βs, is atypical. Its β8 subunit binds to a distinctive cytoskeleton adaptor and does not exhibit large changes in conformation upon binding to ligand. Here, crystal structures, hydrogen-deuterium exchange dynamics, and affinity measurements on mutants are used t...

journal_title：Nature communications

authors： Wang J,Su Y,Iacob RE,Engen JR,Springer TA

更新日期：2019-12-02 00:00:00

abstract：:The emerging monolayer transition metal dichalcogenides have provided an unprecedented material platform for miniaturized opto-electronic devices with integrated functionalities. Although excitonic light-matter interactions associated with their direct bandgaps have received tremendous research efforts, wavefront engi...

journal_title：Nature communications

authors： Qin F,Liu B,Zhu L,Lei J,Fang W,Hu D,Zhu Y,Ma W,Wang B,Shi T,Cao Y,Guan BO,Qiu CW,Lu Y,Li X

更新日期：2021-01-04 00:00:00

abstract：:Predicting ecological effects of contaminants remains challenging because of the sheer number of chemicals and their ambiguous role in biodiversity-ecosystem function relationships. We evaluate responses of experimental pond ecosystems to standardized concentrations of 12 pesticides, nested in four pesticide classes a...

journal_title：Nature communications

authors： Rumschlag SL,Mahon MB,Hoverman JT,Raffel TR,Carrick HJ,Hudson PJ,Rohr JR

更新日期：2020-12-10 00:00:00

abstract：:Topological nodal line semimetals, a novel quantum state of materials, possess topologically nontrivial valence and conduction bands that touch at a line near the Fermi level. The exotic band structure can lead to various novel properties, such as long-range Coulomb interaction and flat Landau levels. Recently, topolo...

journal_title：Nature communications

authors： Feng B,Fu B,Kasamatsu S,Ito S,Cheng P,Liu CC,Feng Y,Wu S,Mahatha SK,Sheverdyaeva P,Moras P,Arita M,Sugino O,Chiang TC,Shimada K,Miyamoto K,Okuda T,Wu K,Chen L,Yao Y,Matsuda I

更新日期：2017-10-18 00:00:00

abstract：:Visual brain areas exhibit tuning characteristics well suited for image statistics present in our natural environment. However, visual sensation is an active process, and if there are any brain areas that ought to be particularly in tune with natural scene statistics, it would be sensory-motor areas critical for guidi...

journal_title：Nature communications

authors： Chen CY,Sonnenberg L,Weller S,Witschel T,Hafed ZM

更新日期：2018-07-20 00:00:00

abstract：:The microbial communities living in the human intestine can have profound impact on our well-being and health. However, we have limited understanding of the mechanisms that control this complex ecosystem. Here, based on a deep phylogenetic analysis of the intestinal microbiota in a thousand western adults, we identify...

journal_title：Nature communications

authors： Lahti L,Salojärvi J,Salonen A,Scheffer M,de Vos WM

更新日期：2014-07-08 00:00:00

abstract：:Acute myeloid leukaemia (AML) affects children and adults of all ages. AML remains one of the major causes of death in children with cancer and for children with AML relapse is the most common cause of death. Here, by modelling AML in vivo we demonstrate that AML is discriminated by the age of the cell of origin. Youn...

journal_title：Nature communications

authors： Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K

更新日期：2018-12-11 00:00:00

abstract：:Membranes with nano-apertures are versatile templates that possess a wide range of electronic, optical and biomedical applications. However, such membranes have been limited to silicon-based inorganic materials to utilize standard semiconductor processes. Here we report a new type of flexible and free-standing polymer...

journal_title：Nature communications

authors： Cho H,Kim J,Park H,Won Bang J,Seop Hyun M,Bae Y,Ha L,Yoon Kim D,Min Kang S,Jung Park T,Seo S,Choi M,Suh KY

更新日期：2014-01-01 00:00:00

abstract：:The concept of spin-torque-driven high-frequency magnetization dynamics, allows the potential construction of complex networks of non-linear dynamical nanoscale systems, combining the field of spintronics and the study of non-linear systems. In the few previous demonstrations of synchronization of several spin-torque ...

journal_title：Nature communications

authors： Lebrun R,Tsunegi S,Bortolotti P,Kubota H,Jenkins AS,Romera M,Yakushiji K,Fukushima A,Grollier J,Yuasa S,Cros V

更新日期：2017-06-12 00:00:00

abstract：:Loss of seed dispersal is a key agronomical trait targeted by ancient human selection and has been regarded as a milestone of crop domestication. In this study, in the legume crop soybean Glycine max (L.) Merr. which provides vegetable oils and proteins for humans, we show that the key cellular feature of the shatteri...

journal_title：Nature communications

authors： Dong Y,Yang X,Liu J,Wang BH,Liu BL,Wang YZ

更新日期：2014-01-01 00:00:00

abstract：:In nature, protein subunits on the capsids of many icosahedral viruses form rotational patterns, and mathematicians also incorporate asymmetric patterns into faces of polyhedra. Chemists have constructed molecular polyhedra with vacant or highly symmetric faces, but very little is known about constructing polyhedra wi...

journal_title：Nature communications

authors： Wang X,Wang Y,Yang H,Fang H,Chen R,Sun Y,Zheng N,Tan K,Lu X,Tian Z,Cao X

更新日期：2016-08-24 00:00:00

abstract：:Quantum computers promise to solve certain problems more efficiently than their digital counterparts. A major challenge towards practically useful quantum computing is characterizing and reducing the various errors that accumulate during an algorithm running on large-scale processors. Current characterization techniqu...

journal_title：Nature communications

authors： Erhard A,Wallman JJ,Postler L,Meth M,Stricker R,Martinez EA,Schindler P,Monz T,Emerson J,Blatt R

更新日期：2019-11-25 00:00:00

abstract：:Proteins are co-translationally inserted into the bacterial plasma membrane via the SecYEG translocon by lateral release of hydrophobic transmembrane segments into the phospholipid bilayer. The trigger for lateral opening of the translocon is not known. Here we monitor lateral opening by photo-induced electron transfe...

journal_title：Nature communications

authors： Ge Y,Draycheva A,Bornemann T,Rodnina MV,Wintermeyer W

更新日期：2014-10-15 00:00:00

abstract：:Nanopatterning by molecular self-assembly has been a topic of intense research in pursuit of 'bottom-up' methods of generating structures for use in nanotechnology. The systems most widely studied have been two- and three-dimensional morphologies of block copolymers. However, T- and X-shaped polyphilic liquid crystals...

journal_title：Nature communications

authors： Liu F,Kieffer R,Zeng X,Pelz K,Prehm M,Ungar G,Tschierske C

更新日期：2012-01-01 00:00:00

abstract：:Approximately half of the world's population lives in the tropics, and future changes in the hydrological cycle will impact not just the freshwater supplies but also energy production in areas dependent upon hydroelectric power. It is vital that we understand the mechanisms/processes that affect tropical precipitation...

journal_title：Nature communications

authors： Winter A,Zanchettin D,Miller T,Kushnir Y,Black D,Lohmann G,Burnett A,Haug GH,Estrella-Martínez J,Breitenbach SF,Beaufort L,Rubino A,Cheng H

更新日期：2015-07-14 00:00:00

abstract：:Mesostriatal dopaminergic neurons possess extensively branched axonal arbours. Whether action potentials are converted to dopamine output in the striatum will be influenced dynamically and critically by axonal properties and mechanisms that are poorly understood. Here, we address the roles for mechanisms governing rel...

journal_title：Nature communications

authors： Condon MD,Platt NJ,Zhang YF,Roberts BM,Clements MA,Vietti-Michelina S,Tseu MY,Brimblecombe KR,Threlfell S,Mann EO,Cragg SJ

更新日期：2019-09-19 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Giulimondi F,Digiacomo L,Pozzi D,Palchetti S,Vulpis E,Capriotti AL,Chiozzi RZ,Laganà A,Amenitsch H,Masuelli L,Peruzzi G,Mahmoudi M,Screpanti I,Zingoni A,Caracciolo G

更新日期：2020-03-31 00:00:00

abstract：:Systems-wide profiling of breast cancer has almost always entailed RNA and DNA analysis by microarray and sequencing techniques. Marked developments in proteomic technologies now enable very deep profiling of clinical samples, with high identification and quantification accuracy. We analysed 40 oestrogen receptor posi...

journal_title：Nature communications

authors： Tyanova S,Albrechtsen R,Kronqvist P,Cox J,Mann M,Geiger T

更新日期：2016-01-04 00:00:00

abstract：:The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats. In the present study we describe that the CeA neuronal ensemble that is activated by withdrawal from chronic alcohol exposure c...

journal_title：Nature communications

authors： de Guglielmo G,Kallupi M,Pomrenze MB,Crawford E,Simpson S,Schweitzer P,Koob GF,Messing RO,George O

更新日期：2019-03-18 00:00:00

abstract：:The ability to modulate nanoparticle (NP) assemblies with atomic precision is still lacking, which hinders us from creating hierarchical NP organizations with desired properties. In this work, a hierarchical fibrous (1D to 3D) assembly of Au NPs (21-gold atom, Au21) is realized and further modulated with atomic precis...

journal_title：Nature communications

authors： Li Q,Russell JC,Luo TY,Roy X,Rosi NL,Zhu Y,Jin R

更新日期：2018-09-24 00:00:00

abstract：:Acid-sensing ion channel 3 (ASIC3) is involved in acid nociception, but its possible role in neurosensory mechanotransduction is disputed. We report here the generation of Asic3-knockout/eGFPf-knockin mice and subsequent characterization of heterogeneous expression of ASIC3 in the dorsal root ganglion (DRG). ASIC3 is ...

journal_title：Nature communications

authors： Lin SH,Cheng YR,Banks RW,Min MY,Bewick GS,Chen CC

更新日期：2016-05-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Osuna-Cruz CM,Bilcke G,Vancaester E,De Decker S,Bones AM,Winge P,Poulsen N,Bulankova P,Verhelst B,Audoor S,Belisova D,Pargana A,Russo M,Stock F,Cirri E,Brembu T,Pohnert G,Piganeau G,Ferrante MI,Mock T,Sterck L,S

更新日期：2020-10-16 00:00:00

abstract：:The unusual electronic properties of diamondoids, the nanoscale relatives of diamond, make them attractive for applications ranging from drug delivery to field emission displays. Identifying the fundamental origin of these properties has proven highly challenging, with even the most advanced quantum many-body calculat...

journal_title：Nature communications

authors： Patrick CE,Giustino F

更新日期：2013-01-01 00:00:00

abstract：:The Human Proteome Organization (HUPO) launched the Human Proteome Project (HPP) in 2010, creating an international framework for global collaboration, data sharing, quality assurance and enhancing accurate annotation of the genome-encoded proteome. During the subsequent decade, the HPP established collaborations, dev...

journal_title：Nature communications

authors： Adhikari S,Nice EC,Deutsch EW,Lane L,Omenn GS,Pennington SR,Paik YK,Overall CM,Corrales FJ,Cristea IM,Van Eyk JE,Uhlén M,Lindskog C,Chan DW,Bairoch A,Waddington JC,Justice JL,LaBaer J,Rodriguez H,He F,Kostrzewa M

更新日期：2020-10-16 00:00:00

abstract：:Inflammation is recognized as one of the drivers of cancer. Yet, the individual immune components that possess pro- and anti-tumorigenic functions in individual cancers remain largely unknown. NKG2D is a potent activating immunoreceptor that has emerged as an important player in inflammatory disorders besides its well...

journal_title：Nature communications

authors： Sheppard S,Guedes J,Mroz A,Zavitsanou AM,Kudo H,Rothery SM,Angelopoulos P,Goldin R,Guerra N

更新日期：2017-01-27 00:00:00