Preoperative widespread pain sensitization and chronic pain after hip and knee replacement: a cohort analysis.

abstract：:Musculoskeletal disorders (MSDs) are highly prevalent, painful, and costly disorders. The MSD Cohort was created to characterize variation in pain, comorbidities, treatment, and outcomes among patients with MSD receiving Veterans Health Administration care across demographic groups, geographic regions, and facilities....

journal_title：Pain

authors： Goulet JL,Kerns RD,Bair M,Becker WC,Brennan P,Burgess DJ,Carroll CM,Dobscha S,Driscoll MA,Fenton BT,Fraenkel L,Haskell SG,Heapy AA,Higgins DM,Hoff RA,Hwang U,Justice AC,Piette JD,Sinnott P,Wandner L,Womack JA,Br

更新日期：2016-08-01 00:00:00

abstract：:Substance P (SP) plays a central role in the transduction of second messenger signals from primary afferent nociceptive terminals to second-order neurons in the spinal cord. We have tested a recombinant engineered diphtheria toxin/SP fusion protein (DAB389SP) in acute and chronic pain models in the rat. DAB389SP binds...

journal_title：Pain

authors： Benoliel R,Eliav E,Mannes AJ,Caudle RM,Leeman S,Iadarola MJ

更新日期：1999-02-01 00:00:00

abstract：:The ascending Method of Limits, used for the determination of pressure pain thresholds (PPT), is not a psychophysically robust method. The present study sought to determine if the examiner's expectancy, based on whether the measurement site was clinically 'painful' or 'non-painful', would bias the obtained PPT values....

journal_title：Pain

authors： Ohrbach R,Crow H,Kamer A

更新日期：1998-02-01 00:00:00

abstract：:The information from nociceptors is processed in the dorsal horn of the spinal cord by complex circuits involving excitatory and inhibitory interneurons. It is well documented that GluN2B and ERK1/2 phosphorylation contributes to central sensitization. Striatal-enriched protein tyrosine phosphatase (STEP) dephosphoryl...

journal_title：Pain

authors： Azkona G,Saavedra A,Aira Z,Aluja D,Xifró X,Baguley T,Alberch J,Ellman JA,Lombroso PJ,Azkue JJ,Pérez-Navarro E

更新日期：2016-02-01 00:00:00

abstract：:Recent studies indicate that reactive oxygen species (ROS) play an important role in neuropathic pain, predominantly through spinal mechanisms. Since the data suggest that ROS are involved in central sensitization, the present study examines the levels of activated N-methyl-d-aspartate (NMDA) receptors in the dorsal h...

journal_title：Pain

authors： Gao X,Kim HK,Mo Chung J,Chung K

更新日期：2007-10-01 00:00:00

abstract：:A mounting body of literature recommends that treatment for fibromyalgia (FM) encompass medications, exercise and improvement of coping skills. However, there is a significant gap in determining an effective counterpart to pharmacotherapy that incorporates both exercise and coping. The aim of this randomized controlle...

journal_title：Pain

authors： Carson JW,Carson KM,Jones KD,Bennett RM,Wright CL,Mist SD

更新日期：2010-11-01 00:00:00

abstract：:Network meta-analysis uses direct comparisons of interventions within randomized controlled trials and indirect comparisons across them. Network meta-analysis uses more data than a series of direct comparisons with placebo, and theoretically should produce more reliable results. We used a Cochrane overview review of a...

journal_title：Pain

authors： Moore RA,Derry S,Wiffen PJ,Banerjee S,Karan R,Glimm E,Wiksten A,Aldington D,Eccleston C

更新日期：2018-11-01 00:00:00

abstract：:Shoulder pain is common in primary care and has an unfavourable outcome in many patients. Information about predictors of outcome is scarce and inconsistent. The objective of this study was to develop clinical prediction rules for calculating the absolute risk of persistent shoulder symptoms for individual patients, 6...

journal_title：Pain

authors： Kuijpers T,van der Windt DAWM,Boeke JPA,Twisk JWR,Vergouwe Y,Bouter LM,van der Heijden GJMG

更新日期：2006-02-01 00:00:00

abstract：:Evidence has shown that electrical stimulation at the dorsal columns attenuated the "wind-up" phenomenon in dorsal horn neurons in nerve-injured rats. This study was aimed to test the effect of spinal cord stimulation (SCS) on temporal summation (TS), the clinical correlate of the wind-up phenomenon in patients with r...

journal_title：Pain

authors： Eisenberg E,Burstein Y,Suzan E,Treister R,Aviram J

更新日期：2015-03-01 00:00:00

abstract：:Iatrogenic Cushing's syndrome has been reported after the use of nasal, aerosol, oral, and intramuscular steroid preparations. Presented is a case of Cushing's syndrome due to an epidural injection of methylprednisolone. A 24-year-old man had left arm pain after an occupational injury. Electromyography revealed C7 rad...

journal_title：Pain

authors： Tuel SM,Meythaler JM,Cross LL

更新日期：1990-01-01 00:00:00

abstract：:Pain symptoms of many disorders are reported to vary with menstrual stage. This study investigated how pain thresholds to electrical stimulation of the skin, subcutis and muscle tissue varied with menstrual stage in normal women and compared these variations with those in women with dysmenorrhea and in healthy men at ...

journal_title：Pain

authors： Giamberardino MA,Berkley KJ,Iezzi S,de Bigontina P,Vecchiet L

更新日期：1997-06-01 00:00:00

abstract：:Expectations modulate the subjective experience of pain by increasing sensitivity to nociceptive inputs, an effect mediated by brain regions such as the insula. However, it is still unknown whether the neural structures underlying pain expectancy hold sensory-specific information or, alternatively, code for modality-i...

journal_title：Pain

authors： Sharvit G,Corradi-DellʼAcqua C,Vuilleumier P

更新日期：2018-08-01 00:00:00

abstract：:For genetic research to contribute more fully to furthering our knowledge of neuropathic pain, we require an agreed, valid, and feasible approach to phenotyping, to allow collaboration and replication in samples of sufficient size. Results from genetic studies on neuropathic pain have been inconsistent and have met wi...

journal_title：Pain

authors： van Hecke O,Kamerman PR,Attal N,Baron R,Bjornsdottir G,Bennett DLH,Bennett MI,Bouhassira D,Diatchenko L,Freeman R,Freynhagen R,Haanpää M,Jensen TS,Raja SN,Rice ASC,Seltzer Z,Thorgeirsson TE,Yarnitsky D,Smith BH

更新日期：2015-11-01 00:00:00

abstract：:Questions concerning stump, phantom and other pain problems as well as demographic data were mailed to 5000 Americans whose amputations were connected with military service. Fifty-five percent responded and of these, 78% reported phantom pain. No predisposing factors, other than presence of stump pain, correlated with...

journal_title：Pain

authors： Sherman RA,Sherman CJ,Parker L

更新日期：1984-01-01 00:00:00

abstract：:With increasing concerns about the potential harm of long-term opioid therapy, there is a need for the development and implementation of alternative treatment strategies for patients with chronic pain who have been using opioids for a prolonged period of time. Based on the findings from a recent qualitative investigat...

journal_title：Pain

authors： Andrews NE,Strong J,Meredith PJ,Fleming JA

更新日期：2016-02-01 00:00:00

abstract：:The aim of the present study was to investigate changes in the plasma calcitonin gene-related peptide (CGRP) concentration and platelet serotonin (5-hydroxytriptamine, 5-HT) content during the immediate headache and the delayed genuine migraine attack provoked by nitroglycerin. Fifteen female migraineurs (without aura...

journal_title：Pain

authors： Juhasz G,Zsombok T,Modos EA,Olajos S,Jakab B,Nemeth J,Szolcsanyi J,Vitrai J,Bagdy G

更新日期：2003-12-01 00:00:00

abstract：:The purpose of this study was to examine racial/ethnic-related differences in a four-stage model of the processing of chronic pain. The subjects were 1557 chronic pain patients (White=1084, African American=473) evaluated at a pain management clinic at a large southeastern university medical center. Using an analysis ...

journal_title：Pain

authors： Riley JL 3rd,Wade JB,Myers CD,Sheffield D,Papas RK,Price DD

更新日期：2002-12-01 00:00:00

abstract：:Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular venous blood of adult migraineurs during acute migraine attacks, it remains unknown whether CGRP is increased outside of attacks in jugular or cubital venous blood. The aim of the present study was to compare interictal plasma lev...

journal_title：Pain

authors： Ashina M,Bendtsen L,Jensen R,Schifter S,Olesen J

更新日期：2000-05-01 00:00:00

abstract：:Chronic pain not only interferes with daily activities, it may also have a negative impact on the perceived integrity of one's self through self-discrepancies. Self-discrepancies are experienced distances between the actual self and self-guides that can exist from 2 perspectives (ie, own and other). Self-discrepancies...

journal_title：Pain

authors： Kindermans HPJ,Huijnen IPJ,Goossens MEJB,Roelofs J,Verbunt JA,Vlaeyen JWS

更新日期：2011-02-01 00:00:00

abstract：:A noxious cold stimulus can evoke multiple sensations each occurring with a different time course. We have performed psychophysical studies to identify the time course of five sensations evoked by a noxious cold stimulus applied to the hand. Subjects continuously rated either pain, ache, cold, heat or prickle sensatio...

journal_title：Pain

authors： Davis KD,Pope GE

更新日期：2002-07-01 00:00:00

abstract：:Visceral inflammation is thought to play an important role in the sensitization of low and high threshold mechanosensory and polymodal afferents and to recruit silent nociceptors. Yet, little is known about the potential role of the mediators involved in nociceptor sensitization to mechanical stimulation as compared t...

journal_title：Pain

authors： Roza C,Reeh PW

更新日期：2001-09-01 00:00:00

abstract：:The objective of this study was to examine pain as a predictor of frailty over 18 years of follow-up among older Mexican Americans who were nonfrail at baseline. Data were from a prospective cohort study of 1545 community-dwelling Mexican Americans aged ≥67 years from the Hispanic Established Populations for the Epide...

journal_title：Pain

authors： Sodhi JK,Karmarkar A,Raji M,Markides KS,Ottenbacher KJ,Al Snih S

更新日期：2020-01-01 00:00:00

abstract：:Chronic dry eye disease (DE) is associated with an unstable tear film and symptoms of ocular discomfort. The characteristics of symptoms suggest a key role for central neural processing; however, little is known about central neuroplasticity and DE. We used a model for tear deficient DE and assessed effects on eye bli...

journal_title：Pain

authors： Rahman M,Okamoto K,Thompson R,Katagiri A,Bereiter DA

更新日期：2015-05-01 00:00:00

abstract：:The field of pediatric pain research began in the mid-1970s and has undergone significant growth and development in recent years as evidenced by the variety of books, conferences, and journals on the topic and also the number of disciplines engaged in work in this area. Using categorical and bibliometric meta-trend an...

journal_title：Pain

authors： Caes L,Boerner KE,Chambers CT,Campbell-Yeo M,Stinson J,Birnie KA,Parker JA,Huguet A,Jordan A,MacLaren Chorney J,Schinkel M,Dol J

更新日期：2016-02-01 00:00:00

abstract：:Chronic postsurgical pain impacts most amputees, with more than half experiencing neuralgic residual limb pain. The transition from normal acute postamputation pain to chronic residual limb pain likely involves both peripheral and central inflammatory mechanisms. As part of the Veterans Integrated Pain Evaluation Rese...

journal_title：Pain

authors： Chamessian A,Van de Ven T,Buchheit T,Hsia HL,McDuffie M,Gamazon ER,Walsh C,Bruehl S,Buckenmaier C' 3rd,Shaw A

更新日期：2017-01-01 00:00:00

abstract：:The behavioral response to acute tissue injury is usually characterized by different phases, but the brain mechanisms underlying changes in pain-related behavior over time are still poorly understood. We aimed to analyze time-dependent changes in metabolic activity levels of 49 forebrain structures in the formalin pai...

journal_title：Pain

authors： Porro CA,Cavazzuti M,Lui F,Giuliani D,Pellegrini M,Baraldi P

更新日期：2003-07-01 00:00:00

abstract：:Current opinion concerning the pathophysiology of tension-type headache (TTH) and its related pericranial muscle tenderness proposes a primary role of central sensitization at the level of dorsalhorn/trigeminal nucleus as well as the supraspinal level. Investigation of these phenomena can be conducted using laser-evok...

journal_title：Pain

authors： de Tommaso M,Libro G,Guido M,Sciruicchio V,Losito L,Puca F

更新日期：2003-07-01 00:00:00

abstract：:Single units were recorded in dorsal roots or in the sciatic nerve of anaesthetised rats. It was shown by making sections, by stimulation and by collision that some ongoing nerve impulses were originating from the dorsal root ganglia and not from the central or peripheral ends of the axons. In a sample of 2731 intact ...

journal_title：Pain

authors： Wall PD,Devor M

更新日期：1983-12-01 00:00:00

abstract：:In a consecutive series of 227 psychiatric hospital admissions, data were recorded in respect of the complaint of pain. Eighty-six (38%) had pain. Fourty-four (19%) mentioned it spontaneously and 49 (22%) had no relevant physical cause. Women were affected more often than men (P less than 0.01) and tended to complain ...

journal_title：Pain

authors： Delaplaine R,Ifabumuyi OI,Merskey H,Zarfas J

更新日期：1978-04-01 00:00:00

abstract：:In the last decade, there has been burgeoning interest in the effectiveness of third-generation psychological therapies for managing fibromyalgia (FM) symptoms. The present study examined the effectiveness of acceptance and commitment therapy (ACT) on functional status as well as the role of pain acceptance as a media...

journal_title：Pain

authors： Luciano JV,Guallar JA,Aguado J,López-Del-Hoyo Y,Olivan B,Magallón R,Alda M,Serrano-Blanco A,Gili M,Garcia-Campayo J

更新日期：2014-04-01 00:00:00