Abstract:
OBJECTIVES:To evaluate the possible effects of the introduction of the pneumococcal conjugate 10-valent vaccine schedule in the state of Parana on pneumococcal meningitis cases and to assess the distribution of serotypes among cases. METHOD:Cross-sectional study with retrospective data collection of cases of pneumococcal meningitis in the state of Paraná reported to Sistema de Informação de Agravos de Notificação (SINAN), from 1998 to 2011. A total of 1,339 cases of pneumococcal meningitis were analyzed; 1,205 cases from the pre-vaccine period (1998-2009) were compared to 134 cases from the post-vaccine period (2010-2011). Descriptive and comparative statistical analyses (chi-squared test and prevalence ratio) were performed using JMP 5.1.2 statistical software (JMP Statistical Discovery, North Carolina, USA) and EPI INFO 6 (Centers for Disease Control and Prevention, Georgia, EUA). RESULTS:There was a significant reduction in the mean rates of incidence and mortality in the general population. The analysis of cases in the pre- and post-vaccination periods in the age groups covered by vaccination (younger than 2 years) showed significant reductions in incidence rates (6.01 cases/100,000 to 2.49 cases/100,000 individuals) and mortality (1.85 cases/100,000 population to 0.47 cases/100,000 population), while the mean lethality rate did not change significantly. There was a significant reduction in cases whose serotypes are included in the vaccine (80.7% to 53.3%). CONCLUSION:Even after a short time of use, the 10-valent pneumococcal conjugate vaccine has already had a significant impact in reducing the incidence and mortality of meningitis cases among infants, as well as the reduction of cases whose serotypes are included in the vaccine.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Hirose TE,Maluf EM,Rodrigues COdoi
10.1016/j.jped.2014.07.002subject
Has Abstractpub_date
2015-03-01 00:00:00pages
130-5issue
2eissn
0021-7557issn
1678-4782pii
S0021-7557(14)00144-2journal_volume
91pub_type
杂志文章abstract::The acute inflammatory demyelinating polyneuropathy (Guillain-Barré Syndrome) might have a severe presentation but a good prognosis in children. It is an immune-mediated and inflammatory disorder of the peripheral nervous system. This retrospective study observed that GBS is frequently complicated by hypertension and ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.579
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:The modified shuttle test is a field test that avoids the ceiling effect, and there are no reports of a multidimensional assessment concerning physical activity in asthmatic patients. Thus, the aim was to evaluate functional capacity by MST, additionally to perform a multidimensional assessment as physical ac...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2018.07.011
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To determine the prevalence of innocent murmur among adolescents, and to evaluate the clinical features in comparison with echocardiogram (two-dimensional, M-mode, Doppler, and color-Doppler) in the assessment of heart murmurs. METHODS:The study was carried out from March to December, 1992, and involved high s...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.636
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:To assess the carotid intima-media thickness and factors associated with cardiovascular disease in children and adolescents with chronic kidney disease. MATERIAL AND METHODS:Observational, cross-sectional study carried out at the Universidade Federal de São Paulo (chronic kidney disease outpatient clinics) w...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2018.06.010
更新日期:2019-01-01 00:00:00
abstract::OBJECTIVES: Air pollution has been a significant worldwide problem with repercussions in the respiratory tract, along the years. The main objectives of this review are to present results from studies on the harmful effects of allergens as well as of pollutants over the respiratory tract.METHOD: Published studies were ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.481
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:Review the literature on excessive crying in young infants, also known as infantile colic, and its effects on family dynamics, its pathophysiology, and new treatment interventions. DATA SOURCE:The literature review was carried out in the Medline, PsycINFO, LILACS, SciELO, and Cochrane Library databases, usin...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2016.01.004
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To analyze the parents' perception of their infants hospitalization in a neonatal intensive care unit (NICU) and suggest a more humane and individualized care in this highly stressful environment. METHODS:We recorded and analyzed the interview of 20 young, low socioeconomic class couples having their first b...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.543
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:To describe the association between electronic devices in the bedroom with sedentary time and physical activity, both assessed by accelerometry, in addition to body mass index in children from São Caetano do Sul. METHODS:The sample consisted of 441 children. The presence of electronic equipment (television, ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2015.01.009
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of and factors associated with overweight in children under 4 years of age in Feira de Santana, state of Bahia, Brazil. METHODS:Cross-sectional study nested within a birth cohort of 793 children born in Feira de Santana, Brazil. Independent variables were related to infant charact...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2009
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:Assess the maternal socio-demographic factors associated with the frequency of use of child care services by low income families. METHODS:Cross-sectional analysis of 393 children between 12 and 16 months old who participated in a randomized field trial during their first year of life in a program of nutritio...
journal_title:Jornal de pediatria
pub_type: 杂志文章,随机对照试验
doi:10.2223/JPED.1966
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306, and rs2227307) and their ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2017.03.005
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To analyze the quality of life of children with stomas according to the children and mothers' point of view; to compare the results related to quality of life in both groups, and to verify the statistical associations between those aspects and children's demographic and clinical data. METHODS:After fulfillin...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. METHODS:Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis and 15 with clinical sepsis)...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2017.03.006
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To draw skinfold (SF) reference curves (subscapular, suprailiac, biceps, triceps) and to determine SF cutoff points for predicting the risk of metabolic syndrome (MetS) in children aged 6-10 years old. METHODS:This was a cross-sectional study with a random sample of 1480 children aged 6-10 years old, 52.2% ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2016.11.013
更新日期:2017-01-01 00:00:00
abstract::Immediate skin test reactions are the hallmark of atopic diseases. EMLA (eutectic mixture of local anesthetics) is a local anesthetic that reduces the pain and apprehension for skin testing. We studied EMLA effects on the skin prick test with allergen and histamine. Reactions were evaluated by means of wheal and flare...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.613
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVE:To analyze the influence of obesity status on immune cell count and concentration of the hormones cortisol and leptin, in order to establish a relationship among the variables analyzed. METHODS:We recruited 27 obese [body mass index (BMI) > or = 95th percentile] and 21 non-obese (BMI < or = 75th percentile) ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1845
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:To describe the characteristics of macrophage activation syndrome associated with juvenile idiopathic arthritis. DESCRIPTION:This is a retrospective study involving 462 patients with juvenile idiopathic arthritis. Seven (1.5%) of those patients suffered from systemic onset juvenile idiopathic arthritis and d...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To develop a predictive model capable of identifying which premature infants have the greatest probability of presenting bronchopulmonary dysplasia (BPD), based on assessment at the end of their first week of life. METHODS:Data were collected retrospectively from January 1998 to July 2001, and prospectively ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1599
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To determine the thyroid stimulating hormone (TSH) secretion in children with Down syndrome (DS), who do not present clinical and laboratory evidence of classical hypothyroidism and concomitant undetectable antibodies. METHODS:Fourteen children with DS with a mean age of 3.4 (+/- 1.8) years were studied. Pat...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:A review article was carried out, addressing the clinical and epidemiological characteristics of immune system deficiencies, which are associated with or predispose to recurrent infectious processes, autoimmune diseases, auto inflammatory diseases, or neoplasms, and which are classified as inborn errors of im...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2020.10.009
更新日期:2020-11-22 00:00:00
abstract:OBJECTIVE:To investigate the association between postpartum depression and the occurrence of exclusive breastfeeding. METHOD:This is a cross-sectional study conducted in the states of the Northeast region, during the vaccination campaign in 2010. The sample consisted of 2583 mother-child pairs, with children aged from...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2016.08.005
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to describe the experience with high-frequency oscillatory ventilation (HFOV) in a Portuguese Pediatric Critical Care Unit, and to evaluate whether HFOV allowed improvement in oxygenation and ventilation. METHODS:This was a retrospective observational cohort study of children ventil...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.02.008
更新日期:2013-01-01 00:00:00
abstract::OBJECTIVE: To review the use of corticosteroids in the treatment of newborns with chronic lung disease, adrenal insufficiency and upper airway edema. SOURCES: Review of the available medical literature on the use of corticosteroids in newborns. SUMMARY OF THE FINDINGS: Although there is evidence of short-term clinical...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.216
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate what effect the ingestion of sardines, rich in omega-3 series polyunsaturated fatty acids, has on the composition of breastmilk. METHODS:This was a prospective study of 31 nursing mothers under observation at the Hospital Guilherme Alvaro. Each was given 2 kg of ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1439
更新日期:2006-01-01 00:00:00
abstract::OBJECTIVE: Morbidity and mortality of premature infants have decreased considerably over the last decades, therefore, adequate nutrition of the premature is a major concern. Enteral feeding is the route of choice, but when it is not possible the parenteral route, which contains glucose as one of its main components, i...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.463
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:To correlate different methods of body composition assessment in overweight or obese schoolchildren, using deuterium oxide (D2O) dilution as a reference. METHODS:Percentage of total body water (%TBW), fat free mass (%FFM), and body fat (%BF) were assessed by D2O and tetrapolar electrical bioimpedance analysi...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2015.03.007
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:to evaluate neonatal sepsis as a risk factor for abnormal neuromotor and cognitive development in very low birth weight preterm infants at 12 months of corrected age. METHODS:this was a prospective cohort study that followed the neuromotor and cognitive development of 194 very low birth weight preterm infant...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.09.006
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:To determine if the number of involved anatomic areas can modify the standard risk groups in pediatric Hodgkin's lymphoma, identifying children who would benefit from a reduction in treatment intensity. METHODS:Retrospective study evaluating age, sex, histology, Ann-Arbor stage, presence of B symptoms, numb...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1891
更新日期:2009-05-01 00:00:00
abstract::OBJECTIVE: Evaluation of epidemiological, clinical and laboratory features of Plasmodium vivax malaria in children and adolescents. METHODS: This study was carried out in the Malaria Program of the Evandro Chagas Institute (Belém, Pará), from January 1995 to November 1996. 100 children and adolescents with the diagnos...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.295
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:Meningococcal disease continues to be a serious public health concern, being associated with high morbidity and mortality rates worldwide, particularly in Brazil. In addition to discussing recent changes in the global epidemiology of meningococcal disease, we also analyze the development and impact of new con...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1495
更新日期:2006-07-01 00:00:00