Abstract：
OBJECTIVES:The aim of the study was to describe the experience with high-frequency oscillatory ventilation (HFOV) in a Portuguese Pediatric Critical Care Unit, and to evaluate whether HFOV allowed improvement in oxygenation and ventilation. METHODS:This was a retrospective observational cohort study of children ventilated by HFOV between January, 2002 and December, 2011. The following parameters were recorded: demographic and clinical data, and blood gases and ventilatory parameters during the first 48 hours of HFOV. RESULTS:80 children were included, with a median age of 1.5 months (min: one week; max: 36 months). Pneumonia (n=50; 62.5%) and bronchiolitis (n=18; 22.5%) were the main diagnoses. Approximately 40% (n=32) of the patients developed acute respiratory distress syndrome (ARDS). Conventional mechanical ventilation was used in 68 (85%) of patients prior to HFOV. All patients who started HFOV had hypoxemia, and 56 (70%) also presented persistent hypercapnia. Two hours after starting HFOV, a significant improvement in SatO2/FiO2 ratio (128±0.63 vs. 163±0.72; p<0.001) that was sustained up to 24 hours of HFOV and a decrease in FiO2 were observed. Since the beginning of HFOV, the mean PCO2 significantly decreased (87±33 vs. 66±25; p<0.001), and the pH significantly improved (7.21±0.17 vs. 7.32±0.15; p<0.001). Overall survival was 83.8%. CONCLUSIONS:HFOV enabled an improvement in hypercapnia and oxygenation. It is a safe option for the treatment of ARDS and severe small airway diseases.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Moniz M,Silvestre C,Nunes P,Abadesso C,Matias E,Loureiro H,Almeida Hdoi
10.1016/j.jped.2013.02.008subject
Has Abstractpub_date
2013-01-01 00:00:00pages
48-55issue
1eissn
0021-7557issn
1678-4782pii
S0021-7557(13)00009-0journal_volume
89pub_type
杂志文章abstract：OBJECTIVES:To show important aspects of gastroduodenal peptic ulcer and of Helicobacter pylori infection in children and adolescents. SOURCES:Technical textbooks and MEDLINE and LILACS databases including publications between 1966 and 2006. SUMMARY OF THE FINDINGS:The etiology of peptic ulcer in children and adolesce...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1529
更新日期：2006-09-01 00:00:00
abstract：:OBJECTIVES: To assess the implementation and the impact of the Breastfeeding Counselling Course WHO/UNICEF on knowledge and skills of health workers. METHODOLOGY: The implementation of the course was assessed by participant observation; the impact on participants was assessed with an experimental controlled study wher...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.267
更新日期：1999-03-01 00:00:00
abstract：OBJECTIVE:This study investigates the nutritional factors that determine the absence of anemia in infants from families with a low socioeconomic background submitted to a nutrition intervention program, as well as iron intake according to recommendations. METHODS:The study included 369 children from a cohort of inhabi...
journal_title：Jornal de pediatria
pub_type： 杂志文章,随机对照试验
doi：10.2223/JPED.1577
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:A review article was carried out, addressing the clinical and epidemiological characteristics of immune system deficiencies, which are associated with or predispose to recurrent infectious processes, autoimmune diseases, auto inflammatory diseases, or neoplasms, and which are classified as inborn errors of im...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2020.10.009
更新日期：2020-11-22 00:00:00
abstract：OBJECTIVE:To meta-analyze health-related quality of life in pediatric patients with chronic kidney disease in comparison to healthy patients according to the dimensions of the PedsQL instrument. SOURCES OF DATA:A systematic review was performed with meta-analysis for the mean difference in each of the health-related q...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2020.10.013
更新日期：2020-12-17 00:00:00
abstract：OBJECTIVE:Review the literature on excessive crying in young infants, also known as infantile colic, and its effects on family dynamics, its pathophysiology, and new treatment interventions. DATA SOURCE:The literature review was carried out in the Medline, PsycINFO, LILACS, SciELO, and Cochrane Library databases, usin...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2016.01.004
更新日期：2016-05-01 00:00:00
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journal_title：Jornal de pediatria
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更新日期：2020-10-26 00:00:00
abstract：OBJECTIVE:Total bilirubin is beneficial for protecting cardiovascular diseases in adults. The authors aimed to investigate the association of total bilirubin, red blood cell, and hemoglobin levels with the prevalence of high blood pressure in children and adolescents. METHODS:A total of 3776 students (aged from 6 to 1...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2017.07.018
更新日期：2018-01-01 00:00:00
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journal_title：Jornal de pediatria
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更新日期：2006-07-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.543
更新日期：1997-09-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.01.009
更新日期：2013-09-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.80
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:To report the results of open challenge tests performed in children fed with cow's milk-free diet. DESCRIPTION:Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1967
更新日期：2010-03-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.10.013
更新日期：2020-01-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.379
更新日期：1999-07-01 00:00:00
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pub_type： 杂志文章
doi：10.2223/jped.742
更新日期：1995-05-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.216
更新日期：2001-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jped.2017.04.006
更新日期：2018-01-01 00:00:00
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doi：10.2223/jped.32
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doi：
更新日期：2002-01-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
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doi：10.2223/JPED.2013
更新日期：2010-07-01 00:00:00
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pub_type： 杂志文章,评审
doi：
更新日期：2005-03-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2016.04.005
更新日期：2012-05-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.678
更新日期：1994-11-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.564
更新日期：1997-11-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.10.003
更新日期：2019-01-01 00:00:00
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journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2017.06.021
更新日期：2017-01-01 00:00:00
