Open challenge for the diagnosis of cow's milk protein allergy.

Abstract:

OBJECTIVE:To report the results of open challenge tests performed in children fed with cow's milk-free diet. DESCRIPTION:Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow's milk open challenge tests were positive in 28 patients (23.1%). A clinical manifestation of cow's milk allergy different from the one presented at diagnosis occurred in 12 (24.9%) patients with positive challenge. Positive challenge was more frequent (p = 0.042) in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3%) when compared to those fed with other exclusion diets (14.5%). CONCLUSION:Open challenge allowed the interruption of exclusion diet in a significant proportion of the patients.

journal_name

J Pediatr (Rio J)

journal_title

Jornal de pediatria

authors

Correa FF,Vieira MC,Yamamoto DR,Speridião Pda G,de Morais MB

doi

10.2223/JPED.1967

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

163-6

issue

2

eissn

0021-7557

issn

1678-4782

journal_volume

86

pub_type

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